Affiliations 

  • 1 CIIMAR/CIMAR-Interdisciplinary Centre of Marine and Environmental Research, University of Porto, Terminal de Cruzeiros do Porto de Leixões, Avenida General Norton de Matos, S/N, P 4450-208 Matosinhos, Portugal
  • 2 Centro de Biotecnologia Agrícola e Agro-alimentar do Alentejo (CEBAL), Instituto Politécnico de Beja (IPBeja), 7801-908 Beja, Portugal
  • 3 Federal Center for Integrated Arctic Research, Russian Academy of Sciences, Arkhangelsk 163000, Russia
  • 4 Department of Biological Sciences, University of Montreal, Montreal, Canada
  • 5 Center for Macroecology, Evolution and Climate, GLOBE Institute, University of Copenhagen, 2100 Copenhagen, Denmark
  • 6 Aquatic Systems Biology Unit, Technical University of Munich, TUM School of Life Sciences, D-85354 Freising, Germany
  • 7 Department of Environmental and Life Sciences-Biology, Karlstad University, 651 88 Karlstad, Sweden
  • 8 Research Associate, Institute of Systematics, Evolution, Biodiversity (ISYEB), National Museum of Natural History (MNHN), CNRS, SU, EPHE, 75005 Paris, France
  • 9 Centro de Investigação de Montanha (CIMO), Instituto Politécnico de Bragança, Bragança, Portugal
  • 10 GeneSEQ Sdn Bhd, Bandar Bukit Beruntung, Rawang 48300, Selangor, Malaysia
  • 11 Department of Neurosciences and Developmental Biology, University of Vienna, 1010 Vienna, Austria
DNA Res, 2021 May 02;28(2).
PMID: 33755103 DOI: 10.1093/dnares/dsab002

Abstract

Since historical times, the inherent human fascination with pearls turned the freshwater pearl mussel Margaritifera margaritifera (Linnaeus, 1758) into a highly valuable cultural and economic resource. Although pearl harvesting in M. margaritifera is nowadays residual, other human threats have aggravated the species conservation status, especially in Europe. This mussel presents a myriad of rare biological features, e.g. high longevity coupled with low senescence and Doubly Uniparental Inheritance of mitochondrial DNA, for which the underlying molecular mechanisms are poorly known. Here, the first draft genome assembly of M. margaritifera was produced using a combination of Illumina Paired-end and Mate-pair approaches. The genome assembly was 2.4 Gb long, possessing 105,185 scaffolds and a scaffold N50 length of 288,726 bp. The ab initio gene prediction allowed the identification of 35,119 protein-coding genes. This genome represents an essential resource for studying this species' unique biological and evolutionary features and ultimately will help to develop new tools to promote its conservation.

* Title and MeSH Headings from MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.