Affiliations 

  • 1 Department of Physics, Faculty of Science, University of Malaya, 50603, Kuala Lumpur, Malaysia
  • 2 Department of Physics, Faculty of Science, University of Malaya, 50603, Kuala Lumpur, Malaysia. Electronic address: s.fairus@um.edu.my
  • 3 Clinical Oncology Unit, Faculty of Medicine, University of Malaya, 50603, Kuala Lumpur, Malaysia
  • 4 Department of Physics, Princess Nourah Bint Abdulrahman University, Riyadh, Saudi Arabia
  • 5 Department of Physics, University of Surrey, Guildford, GU2 7XH, UK; Sunway University, Centre for Biomedicals Physics, Jalan Universiti, 46150, PJ, Malaysia
Appl Radiat Isot, 2021 Oct;176:109814.
PMID: 34175543 DOI: 10.1016/j.apradiso.2021.109814

Abstract

Brachytherapy is commonly used in treatment of cervical, prostate, breast and skin cancers, also for oral cancers, typically via the application of sealed radioactive sources that are inserted within or alongside the area to be treated. A particular aim of the various brachytherapy techniques is to accurately transfer to the targeted tumour the largest possible dose, at the same time minimizing dose to the surrounding normal tissue, including organs at risk. The dose fall-off with distance from the sources is steep, the dose gradient representing a prime factor in determining the dose distribution, also representing a challenge to the conduct of measurements around sources. Amorphous borosilicate glass (B2O3) in the form of microscope cover slips is recognized to offer a practicable system for such thermoluminescence dosimetry (TLD), providing for high-spatial resolution (down to 

* Title and MeSH Headings from MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.