Affiliations 

  • 1 South Asian Clinical Toxicology Research Collaboration, Faculty of Medicine, 54692University of Peradeniya, Peradeniya, Sri Lanka
  • 2 Department of Community Medicine, Faculty of Medicine, 54692University of Peradeniya, Peradeniya, Sri Lanka
  • 3 Department of Pharmacology, Faculty of Medicines, 4334University of Ruhuna, Galle, Sri Lanka
J Child Health Care, 2023 Mar;27(1):105-115.
PMID: 34719983 DOI: 10.1177/13674935211046101

Abstract

Caregivers are primarily responsible for the administration of Over The Counter (OTC) medications in children. This study examines the mothers' ability to determine and measure paracetamol doses for children aged between 1 and 5 years. A contrived observational study was conducted for mothers of preschool aged children at two Public Health Midwifery (PHM) areas in Southern province, Sri Lanka. Stratified random sampling was used. Only 26.9% (n = 95, 95% CI = 22.5%-31.7%) of the 353 participants correctly determined and measured the doses of paracetamol. Errors were frequently made in both determining and measuring dose together (n = 113, 32.0%, 95% CI = 27.3%-37.1%), determining only (n = 94, 26.6%, 95% CI = 22.2%-31.5%) and measurement only (n = 51, 14.4%, 95% CI = 11.1%-18.5%). Dose determined errors were not significantly associated with maternal education, number of children in the family, total monthly income and age of the index child. Similarly measuring errors were not significantly associated with mothers' education, income of the family and number of children in the family. However, there was a weak positive correlation between measuring errors and age of the index child. The study suggests that mothers made errors when determining doses and measuring doses of paracetamol. Results emphasize importance of clear, concise guardian information leaflet and healthcare professionals' guidance to minimize dosing errors of child medication.

* Title and MeSH Headings from MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.