Testosterone decreases the expression of endometrial pinopode and L-selectin ligand (MECA-79) in adult female rats during uterine receptivity period

Mokhtar HM 1 , Giribabu N 1 , Muniandy S 2 , Salleh N 1

Affiliations 

  • 1 Department of Physiology, Faculty of Medicine, University of Malaya 50603 Lembah Pantai, Kuala Lumpur, Malaysia
  • 2 Department of Molecular Medicine, Faculty of Medicine, University of Malaya 50603 Lembah Pantai, Kuala Lumpur, Malaysia
Int J Clin Exp Pathol, 2014;7(5):1967-76.
PMID: 24966906

Abstract

Pinopode, a progesterone-dependent endometrial projection which appears during uterine receptivity period, participates in blastocyst implantation. Blastocyst loosely attaches to pinopode via L-selectin ligand (MECA-79). We hypothesized that pinopode and MECA-79 expressions were affected by testosterone. Therefore, the effect of testosterone on pinopode and MECA-79 expressions during uterine receptivity period were investigated.

* Title and MeSH Headings from MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.

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