Sarcopenia with co-existent type 2 diabetes mellitus is associated with worse clinical outcomes among hospitalised cardiac patients

Sundar VV 1 , Ong SH 2 , Easaw MEPM 3 , Chee WSS 4

Affiliations 

  • 1 Department of Nutrition and Dietetics, School of Health Sciences, International Medical University, No.126, Jalan Jalil Perkasa 19, Bukit Jalil, 57000, Kuala Lumpur, Malaysia; Dietetics and Food Services, National Heart Institute, 145, Jalan Tun Razak, 50400, Kuala Lumpur, Malaysia. Electronic address: vatana@ijn.com.my
  • 2 Department of Nutrition and Dietetics, School of Health Sciences, International Medical University, No.126, Jalan Jalil Perkasa 19, Bukit Jalil, 57000, Kuala Lumpur, Malaysia. Electronic address: ongshuhwa@imu.edu.my
  • 3 Department of Nutrition and Dietetics, School of Health Sciences, International Medical University, No.126, Jalan Jalil Perkasa 19, Bukit Jalil, 57000, Kuala Lumpur, Malaysia. Electronic address: maryeasaw@imu.edu.my
  • 4 Department of Nutrition and Dietetics, School of Health Sciences, International Medical University, No.126, Jalan Jalil Perkasa 19, Bukit Jalil, 57000, Kuala Lumpur, Malaysia. Electronic address: winnie_chee@imu.edu.my
Clin Nutr ESPEN, 2021 12;46:380-385.
PMID: 34857224 DOI: 10.1016/j.clnesp.2021.08.039

Abstract

BACKGROUND & AIMS: Sarcopenia has been shown associated with functional decline, disability, poorer quality of life and mortality. However, there are limited studies among hospitalised cardiac patients in Malaysia. This study aimed to identify the association of sarcopenia and type 2 diabetes mellitus (T2DM) with clinical outcomes among hospitalised cardiac patients.

METHODS: This prospective observational study assessed 100 patients who were admitted to the general wards at the National Heart Institute. We measured handgrip strength, body composition using bioelectrical impedance analysis (BIA) and recorded the length of stay (LOS), unplanned readmission and incidence of infection within 90 days after discharge. Logistic regression analysis at a significant level p 

* Title and MeSH Headings from MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.

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