Displaying publications 1 - 20 of 162 in total

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  1. Alhabshi SM, Rahmat K, Abdul Halim N, Aziz S, Radhika S, Gan GC, et al.
    Ultrasound Med Biol, 2013 Apr;39(4):568-78.
    PMID: 23384468 DOI: 10.1016/j.ultrasmedbio.2012.10.016
    The purpose of this study was to evaluate the diagnostic value of qualitative and semi-quantitative assessment of ultrasound elastography in differentiating between benign and malignant breast lesions. This prospective study was conducted in two tertiary medical centers. Consecutive B-mode ultrasound and real-time elastographic images were obtained for 67 malignant and 101 benign breast lesions in 168 women. Four experienced radiologists analyzed B-mode ultrasound alone and B-mode ultrasound combined with elastography independently. Conventional ultrasound findings were classified according to the American College of Radiology Breast Imaging Reporting and Data System classification. The elastographic assessment was based on qualitative and semi-quantitative parameters (i.e., strain pattern, width ratio, strain ratio). The sensitivity and specificity of combined elastography and conventional ultrasound were significantly higher than that of conventional ultrasound alone. The sensitivity, specificity, positive predictive value and negative predictive value was 97%, 61.4%, 62.5% and 96.8%, respectively, for conventional ultrasound and 100%, 93%, 99% and 90%, respectively, for combined technique. The semi-quantitative assessment with strain ratio and width ratio in elastography were the most useful parameters in differentiating between benign and malignant breast lesions. Cut-off point values for width ratio of more than 1.1 and strain ratio of more than 5.6 showed a high predictive value of malignancy with specificities of 84% and 76%, respectively (p 
    Matched MeSH terms: Image Interpretation, Computer-Assisted/methods*
  2. Raghavendra U, Rajendra Acharya U, Gudigar A, Hong Tan J, Fujita H, Hagiwara Y, et al.
    Ultrasonics, 2017 05;77:110-120.
    PMID: 28219805 DOI: 10.1016/j.ultras.2017.02.003
    Thyroid is a small gland situated at the anterior side of the neck and one of the largest glands of the endocrine system. The abrupt cell growth or malignancy in the thyroid gland may cause thyroid cancer. Ultrasound images distinctly represent benign and malignant lesions, but accuracy may be poor due to subjective interpretation. Computer Aided Diagnosis (CAD) can minimize the errors created due to subjective interpretation and assists to make fast accurate diagnosis. In this work, fusion of Spatial Gray Level Dependence Features (SGLDF) and fractal textures are used to decipher the intrinsic structure of benign and malignant thyroid lesions. These features are subjected to graph based Marginal Fisher Analysis (MFA) to reduce the number of features. The reduced features are subjected to various ranking methods and classifiers. We have achieved an average accuracy, sensitivity and specificity of 97.52%, 90.32% and 98.57% respectively using Support Vector Machine (SVM) classifier. The achieved maximum Area Under Curve (AUC) is 0.9445. Finally, Thyroid Clinical Risk Index (TCRI) a single number is developed using two MFA features to discriminate the two classes. This prototype system is ready to be tested with huge diverse database.
    Matched MeSH terms: Image Interpretation, Computer-Assisted/methods*
  3. Moghaddasi Z, Jalab HA, Md Noor R, Aghabozorgi S
    ScientificWorldJournal, 2014;2014:606570.
    PMID: 25295304 DOI: 10.1155/2014/606570
    Digital image forgery is becoming easier to perform because of the rapid development of various manipulation tools. Image splicing is one of the most prevalent techniques. Digital images had lost their trustability, and researches have exerted considerable effort to regain such trustability by focusing mostly on algorithms. However, most of the proposed algorithms are incapable of handling high dimensionality and redundancy in the extracted features. Moreover, existing algorithms are limited by high computational time. This study focuses on improving one of the image splicing detection algorithms, that is, the run length run number algorithm (RLRN), by applying two dimension reduction methods, namely, principal component analysis (PCA) and kernel PCA. Support vector machine is used to distinguish between authentic and spliced images. Results show that kernel PCA is a nonlinear dimension reduction method that has the best effect on R, G, B, and Y channels and gray-scale images.
    Matched MeSH terms: Image Interpretation, Computer-Assisted
  4. Zakaria NM, Yusoff NI, Hardwiyono S, Nayan KA, El-Shafie A
    ScientificWorldJournal, 2014;2014:594797.
    PMID: 25276854 DOI: 10.1155/2014/594797
    Enhanced resonance search (ERS) is a nondestructive testing method that has been created to evaluate the quality of a pavement by means of a special instrument called the pavement integrity scanner (PiScanner). This technique can be used to assess the thickness of the road pavement structure and the profile of shear wave velocity by using the principle of surface wave and body wave propagation. In this study, the ERS technique was used to determine the actual thickness of the asphaltic pavement surface layer, while the shear wave velocities obtained were used to determine its dynamic elastic modulus. A total of fifteen locations were identified and the results were then compared with the specifications of the Malaysian PWD, MDD UKM, and IKRAM. It was found that the value of the elastic modulus of materials is between 3929 MPa and 17726 MPa. A comparison of the average thickness of the samples with the design thickness of MDD UKM showed a difference of 20 to 60%. Thickness of the asphalt surface layer followed the specifications of Malaysian PWD and MDD UKM, while some of the values of stiffness obtained are higher than the standard.
    Matched MeSH terms: Image Interpretation, Computer-Assisted/methods
  5. Imran M, Hashim R, Noor Elaiza AK, Irtaza A
    ScientificWorldJournal, 2014;2014:752090.
    PMID: 25121136 DOI: 10.1155/2014/752090
    One of the major challenges for the CBIR is to bridge the gap between low level features and high level semantics according to the need of the user. To overcome this gap, relevance feedback (RF) coupled with support vector machine (SVM) has been applied successfully. However, when the feedback sample is small, the performance of the SVM based RF is often poor. To improve the performance of RF, this paper has proposed a new technique, namely, PSO-SVM-RF, which combines SVM based RF with particle swarm optimization (PSO). The aims of this proposed technique are to enhance the performance of SVM based RF and also to minimize the user interaction with the system by minimizing the RF number. The PSO-SVM-RF was tested on the coral photo gallery containing 10908 images. The results obtained from the experiments showed that the proposed PSO-SVM-RF achieved 100% accuracy in 8 feedback iterations for top 10 retrievals and 80% accuracy in 6 iterations for 100 top retrievals. This implies that with PSO-SVM-RF technique high accuracy rate is achieved at a small number of iterations.
    Matched MeSH terms: Image Interpretation, Computer-Assisted/methods*
  6. Gan HS, Swee TT, Abdul Karim AH, Sayuti KA, Abdul Kadir MR, Tham WK, et al.
    ScientificWorldJournal, 2014;2014:294104.
    PMID: 24977191 DOI: 10.1155/2014/294104
    Well-defined image can assist user to identify region of interest during segmentation. However, complex medical image is usually characterized by poor tissue contrast and low background luminance. The contrast improvement can lift image visual quality, but the fundamental contrast enhancement methods often overlook the sudden jump problem. In this work, the proposed bihistogram Bezier curve contrast enhancement introduces the concept of "adequate contrast enhancement" to overcome sudden jump problem in knee magnetic resonance image. Since every image produces its own intensity distribution, the adequate contrast enhancement checks on the image's maximum intensity distortion and uses intensity discrepancy reduction to generate Bezier transform curve. The proposed method improves tissue contrast and preserves pertinent knee features without compromising natural image appearance. Besides, statistical results from Fisher's Least Significant Difference test and the Duncan test have consistently indicated that the proposed method outperforms fundamental contrast enhancement methods to exalt image visual quality. As the study is limited to relatively small image database, future works will include a larger dataset with osteoarthritic images to assess the clinical effectiveness of the proposed method to facilitate the image inspection.
    Matched MeSH terms: Image Interpretation, Computer-Assisted/methods*
  7. Rassem TH, Khoo BE
    ScientificWorldJournal, 2014;2014:373254.
    PMID: 24977193 DOI: 10.1155/2014/373254
    Despite the fact that the two texture descriptors, the completed modeling of Local Binary Pattern (CLBP) and the Completed Local Binary Count (CLBC), have achieved a remarkable accuracy for invariant rotation texture classification, they inherit some Local Binary Pattern (LBP) drawbacks. The LBP is sensitive to noise, and different patterns of LBP may be classified into the same class that reduces its discriminating property. Although, the Local Ternary Pattern (LTP) is proposed to be more robust to noise than LBP, however, the latter's weakness may appear with the LTP as well as with LBP. In this paper, a novel completed modeling of the Local Ternary Pattern (LTP) operator is proposed to overcome both LBP drawbacks, and an associated completed Local Ternary Pattern (CLTP) scheme is developed for rotation invariant texture classification. The experimental results using four different texture databases show that the proposed CLTP achieved an impressive classification accuracy as compared to the CLBP and CLBC descriptors.
    Matched MeSH terms: Image Interpretation, Computer-Assisted/methods*
  8. Abdullah MZ, Yin W, Bilal M, Armitage DW, Mackin R, Peyton AJ
    Rev Sci Instrum, 2007 Aug;78(8):084703.
    PMID: 17764343
    This article addresses time-domain ultrawide band (UWB) electromagnetic tomography for reconstructing the unknown spatial characteristic of an object from observations of the arrivals of short electromagnetic (EM) pulses. Here, the determination of the first peak arrival of the EM traces constitutes the forward problem, and the inverse problem aims to reconstruct the EM property distribution of the media. In this article, the finite-difference time-domain method implementing a perfectly matched layer is used to solve the forward problem from which the system sensitivity maps are determined. Image reconstruction is based on the combination of a linearized update and regularized Landweber minimization algorithm. Experimental data from a laboratory UWB system using targets of different contrasts, sizes, and shapes in an aqueous media are presented. The results show that this technique can accurately detect and locate unknown targets in spite of the presence of significant levels of noise in the data.
    Matched MeSH terms: Image Interpretation, Computer-Assisted/methods*
  9. Harwant S
    Med J Malaysia, 2001 Dec;56 Suppl D:48-53.
    PMID: 14569767
    Non-traumatic, progressing sagittal plane deformities are uncommon, but can lead to neurological deficit if untreated. The currently used Cobb method in assessing sagittal spinal curves is based on measuring the tilt of the end vertebrae. This study describes a method which quantifies the apex of the sagittal curve based on the apical quality as measured by the radius of curvature. Both this and the Cobb methods are compared to determine which has relevance in determining neurological deficit. Radiographs of 36 consecutive patients diagnosed with congenital kyphosis were reviewed. Twenty-four had normal neurology and 12 had neurological deficit as a result of sagittal curve progression. Both groups of patients had their weight bearing lateral radiographs analysed to measure the sagittal curve by the usual Cobb method and the Radius of Curvature method. There was no difference for the Cobb values for negative neurology and patients with positive neurological deficit (p = 0.3). There was a difference in these two groups when the radius of curvature method was used (p < 0.0005). The Radius of Curvature method has more relevance than Cobb method in quantifying sagittal plane deformity in congenital kyphosis when assessing neurological deficit.
    Matched MeSH terms: Radiographic Image Interpretation, Computer-Assisted*
  10. Cheah PL, Looi LM
    Malays J Pathol, 2007 Jun;29(1):37-40.
    PMID: 19105327 MyJurnal
    Hepatocellular carcinoma (HCC) ranks as the fifth most common cancer with an increasing frequency worldwide. "Nuclear atypia", one of the critical features in histological diagnosis of malignancy and grading of the tumour, is generally ascertained through eyeballing. A study was conducted at the Department of Pathology, University of Malaya Medical Centre to assess whether nuclear area, (surrogate measure for nuclear size) and standard deviation (surrogate measure for nuclear pleomorphism) when objectively measured via computer-linked image analysis differs between (1) benign and malignant liver cells and (2) different grades of HCC. A 4-microm thick H&E stained section of 52 histologically re-confirmed HCC with 36 having benign, non-dysplastic surrounding liver were analysed using the Leica Q550 CW system. 10 consecutive non-overlapping, non-mitotic and non-apoptotic nuclei of HCC and surrounding benign hepatocytes respectively were manually traced at 400x magnification on the computer monitor and the nuclear area for the particular cell computed in arbitrary units by the Leica QWIN software. A total of 360 benign hepatocytic nuclei, 240 low grade HCC and 280 high grade HCC nuclei were traced. The mean nuclear area of the benign hepatocytes (37.3) was significantly smaller (p < 0.05) than that of both low grade (65.2) and high grade HCC (80.0). In addition, the mean nuclear area of high grade HCC was significantly larger (p < 0.05) than the low grade HCC. SD of the nuclear areas was lowest in benign hepatocytes (9.3), intermediate in low grade HCC (25.0) and highest in high grade HCC (25.6). These findings indicate that computer-linked nuclear measurement may be a useful adjunct in differentiating benign from malignant hepatocytes, in particular in small biopsies of well-differentiated tumours, and in predicting survival after surgical resection and transplant.
    Matched MeSH terms: Image Interpretation, Computer-Assisted*
  11. Mahmood WA, Watson CJ, Ogden AR, Hawkins RV
    Int J Prosthodont, 1992 Jul-Aug;5(4):359-66.
    PMID: 1520458
    Image analysis was used to determine masticatory efficiency and performance before and after placement of immediate dentures. Sections of cored carrot were used as the test food and the particle size of chewed expectorated food was measured using image analysis. Measurements were shown to be accurate and reproducible. Masticatory function of immediate-denture patients was also compared with a similar number of dentate individuals and experienced complete-denture wearers. Dentate subjects were significantly (P less than .01) more efficient at masticating the test food than were the complete- or immediate-denture wearers. The new method of measurement removes the necessity for the unpleasant and unhygienic sieving process previously used in this type of study.
    Matched MeSH terms: Image Interpretation, Computer-Assisted*
  12. Rajion ZA, Townsend GC, Netherway DJ, Anderson PJ, Yusof A, Hughes T, et al.
    Cleft Palate Craniofac J, 2006 Sep;43(5):513-8.
    PMID: 16986980
    To investigate anatomical variations and abnormalities of cervical spine morphology in unoperated infants with cleft lip and palate.
    Matched MeSH terms: Image Interpretation, Computer-Assisted
  13. Lau S, Ng KH, Abdul Aziz YF
    Br J Radiol, 2016 Oct;89(1066):20160258.
    PMID: 27452264 DOI: 10.1259/bjr.20160258
    OBJECTIVE: To investigate the sensitivity and robustness of a volumetric breast density (VBD) measurement system to errors in the imaging physics parameters including compressed breast thickness (CBT), tube voltage (kVp), filter thickness, tube current-exposure time product (mAs), detector gain, detector offset and image noise.

    METHODS: 3317 raw digital mammograms were processed with Volpara(®) (Matakina Technology Ltd, Wellington, New Zealand) to obtain fibroglandular tissue volume (FGV), breast volume (BV) and VBD. Errors in parameters including CBT, kVp, filter thickness and mAs were simulated by varying them in the Digital Imaging and Communications in Medicine (DICOM) tags of the images up to ±10% of the original values. Errors in detector gain and offset were simulated by varying them in the Volpara configuration file up to ±10% from their default values. For image noise, Gaussian noise was generated and introduced into the original images.

    RESULTS: Errors in filter thickness, mAs, detector gain and offset had limited effects on FGV, BV and VBD. Significant effects in VBD were observed when CBT, kVp, detector offset and image noise were varied (p 

    Matched MeSH terms: Radiographic Image Interpretation, Computer-Assisted
  14. Acharya UR, Molinari F, Sree SV, Swapna G, Saba L, Guerriero S, et al.
    Technol Cancer Res Treat, 2015 Jun;14(3):251-61.
    PMID: 25230716 DOI: 10.1177/1533034614547445
    Ovarian cancer is the most common cause of death among gynecological malignancies. We discuss different types of clinical and nonclinical features that are used to study and analyze the differences between benign and malignant ovarian tumors. Computer-aided diagnostic (CAD) systems of high accuracy are being developed as an initial test for ovarian tumor classification instead of biopsy, which is the current gold standard diagnostic test. We also discuss different aspects of developing a reliable CAD system for the automated classification of ovarian cancer into benign and malignant types. A brief description of the commonly used classifiers in ultrasound-based CAD systems is also given.
    Matched MeSH terms: Image Interpretation, Computer-Assisted/methods
  15. Yusof MI, Hassan E, Abdullah S
    Surg Radiol Anat, 2011 Mar;33(2):109-15.
    PMID: 20658232 DOI: 10.1007/s00276-010-0704-7
    Posterior translation of the spinal cord occurs passively following laminoplasty with the presence lordotic spine and availability of a space for the spinal cord to shift. This study is to predict the distance of posterior spinal cord migration after expansive laminoplasty at different cervical levels based on measurement of posterior translation of the spinal cord in normal cervical morphometry.
    Matched MeSH terms: Image Interpretation, Computer-Assisted
  16. Abdullah B, Rajet KA, Abd Hamid SS, Mohammad WM
    Sleep Breath, 2011 Dec;15(4):747-54.
    PMID: 20957444 DOI: 10.1007/s11325-010-0431-7
    OBJECTIVES: We aimed to evaluate the severity of upper airway obstruction at the retropalatal and retroglossal regions in obstructive sleep apnea (OSA) patients.

    METHODOLOGY: This is a descriptive cross-sectional study at the Sleep Clinic, Department of Otorhinolaryngology-Head and Neck Surgery. Flexible nasopharyngolaryngoscopy was performed in seated erect and supine position. Retropalatal and retroglossal regions were continuously recorded during quiet breathing and Mueller's maneuver in both positions. Captured images were measured using Scion Image software and narrowing rate was calculated. Level of each site was classified based on Fujita classification and severity of obstruction using Sher scoring system for Mueller's maneuver.

    RESULTS: A total of 59 patients participated in this study. Twenty-nine (49.2%) participants had type 1 (retropalatal) obstruction, 23 (38.9%) had type 2 (retropalatal and retroglossal), and seven (11.9%) in type 3 (retroglossal) obstruction. Fifty (84.7%) of the patients have severe obstruction at the retropalatal region in supine position (SRP) followed by 35 (59.3%) at retropalatal region in erect position (ERP), 27 (45.8%) at retroglossal region in supine position (SRG) and eight (13.5%) at retroglossal region in erect position (ERG). The average oxygen saturation showed significant association in ERP (P = 0.012) and SRP (P < 0.001), but not significant in ERG and SRG.

    CONCLUSIONS: Videoendoscopy utilizing flexible nasopharyngolaryngoscopy and Scion Image software is reliable, minimally invasive, and useful as an office procedure in evaluating the multilevel obstruction of upper airway in OSA patients. The retropalatal region has more severe obstruction compared with retroglossal region either in erect or supine position.

    Matched MeSH terms: Image Interpretation, Computer-Assisted/instrumentation
  17. Malik AS, Humayun J, Kamel N, Yap FB
    Skin Res Technol, 2014 Aug;20(3):322-31.
    PMID: 24329769 DOI: 10.1111/srt.12122
    BACKGROUND: More than 99% acne patients suffer from acne vulgaris. While diagnosing the severity of acne vulgaris lesions, dermatologists have observed inter-rater and intra-rater variability in diagnosis results. This is because during assessment, identifying lesion types and their counting is a tedious job for dermatologists. To make the assessment job objective and easier for dermatologists, an automated system based on image processing methods is proposed in this study.
    OBJECTIVES: There are two main objectives: (i) to develop an algorithm for the enhancement of various acne vulgaris lesions; and (ii) to develop a method for the segmentation of enhanced acne vulgaris lesions.
    METHODS: For the first objective, an algorithm is developed based on the theory of high dynamic range (HDR) images. The proposed algorithm uses local rank transform to generate the HDR images from a single acne image followed by the log transformation. Then, segmentation is performed by clustering the pixels based on Mahalanobis distance of each pixel from spectral models of acne vulgaris lesions.
    RESULTS: Two metrics are used to evaluate the enhancement of acne vulgaris lesions, i.e., contrast improvement factor (CIF) and image contrast normalization (ICN). The proposed algorithm is compared with two other methods. The proposed enhancement algorithm shows better result than both the other methods based on CIF and ICN. In addition, sensitivity and specificity are calculated for the segmentation results. The proposed segmentation method shows higher sensitivity and specificity than other methods.
    CONCLUSION: This article specifically discusses the contrast enhancement and segmentation for automated diagnosis system of acne vulgaris lesions. The results are promising that can be used for further classification of acne vulgaris lesions for final grading of the lesions.
    KEYWORDS: acne grading; acne lesions; acne vulgaris; enhancement; segmentation
    Matched MeSH terms: Image Interpretation, Computer-Assisted/methods*
  18. Ramli R, Malik AS, Hani AF, Jamil A
    Skin Res Technol, 2012 Feb;18(1):1-14.
    PMID: 21605170 DOI: 10.1111/j.1600-0846.2011.00542.x
    INTRODUCTION: This paper presents a comprehensive review of acne grading and measurement. Acne is a chronic disorder of the pilosebaceous units, with excess sebum production, follicular epidermal hyperproliferation, inflammation and Propionibacterium acnes activity. Most patients are affected with acne vulgaris, which is the prevalent type of acne. Acne vulgaris consists of comedones (whitehead and blackhead), papules, pustules, nodules and cysts.
    OBJECTIVES: To review and identify the issues for acne vulgaris grading and computational assessment methods. To determine the future direction for addressing the identified issues.
    METHODS: There are two main methods of assessment for acne severity grading, namely, lesion counting and comparison of patient with a photographic standard. For the computational assessment method, the emphasis is on computational imaging techniques.
    RESULTS: Current acne grading methods are very time consuming and tedious. Generally, they rely on approximation for counting lesions and hence the assessment is quite subjective, with both inter and intra-observer variability. It is important to accurately assess acne grade to evaluate its severity as this influences treatment selection and assessment of response to therapy. This will further help in better disease management and more efficacious treatment.
    CONCLUSION: Semi-automated or automated methods based on computational imaging techniques should be devised for acne grade assessment.
    Matched MeSH terms: Image Interpretation, Computer-Assisted/methods*
  19. Mohafez H, Ahmad SA, Hadizadeh M, Moghimi S, Roohi SA, Marhaban MH, et al.
    Skin Res Technol, 2018 Feb;24(1):45-53.
    PMID: 28557064 DOI: 10.1111/srt.12388
    PURPOSE: We aimed to develop a method for quantitative assessment of wound healing in ulcerated diabetic feet.

    METHODS: High-frequency ultrasound (HFU) images of 30 wounds were acquired in a controlled environment on post-debridement days 7, 14, 21, and 28. Meaningful features portraying changes in structure and intensity of echoes during healing were extracted from the images, their relevance and discriminatory power being verified by analysis of variance. Relative analysis of tissue healing was conducted by developing a features-based healing function, optimised using the pattern-search method. Its performance was investigated through leave-one-out cross-validation technique and reconfirmed using principal component analysis.

    RESULTS: The constructed healing function could depict tissue changes during healing with 87.8% accuracy. The first principal component derived from the extracted features demonstrated similar pattern to the constructed healing function, accounting for 86.3% of the data variance.

    CONCLUSION: The developed wound analysis technique could be a viable tool in quantitative assessment of diabetic foot ulcers during healing.

    Matched MeSH terms: Image Interpretation, Computer-Assisted/methods
  20. Idroas M, Rahim RA, Green RG, Ibrahim MN, Rahiman MH
    Sensors (Basel), 2010;10(10):9512-28.
    PMID: 22163423 DOI: 10.3390/s101009512
    This research investigates the use of charge coupled device (abbreviated as CCD) linear image sensors in an optical tomographic instrumentation system used for sizing particles. The measurement system, consisting of four CCD linear image sensors are configured around an octagonal shaped flow pipe for a four projections system is explained. The four linear image sensors provide 2,048 pixel imaging with a pixel size of 14 micron × 14 micron, hence constituting a high-resolution system. Image reconstruction for a four-projection optical tomography system is also discussed, where a simple optical model is used to relate attenuation due to variations in optical density, [R], within the measurement section. Expressed in matrix form this represents the forward problem in tomography [S] [R] = [M]. In practice, measurements [M] are used to estimate the optical density distribution by solving the inverse problem [R] = [S](-1)[M]. Direct inversion of the sensitivity matrix, [S], is not possible and two approximations are considered and compared-the transpose and the pseudo inverse sensitivity matrices.
    Matched MeSH terms: Image Interpretation, Computer-Assisted/instrumentation*; Image Interpretation, Computer-Assisted/methods*
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