MyMedR

Glucose-6-phosphate dehydrogenase enzyme activity of normal term Malaysian neonates of different ethnic origins

Boo NY, Ainoon BO, Ooi LH, Cheong SK, Haliza BM

J Paediatr Child Health, 1994 Jun;30(3):273-4.

The cord blood glucose-6-phosphate dehydrogenase (G6PD) enzyme activity of 262 normal term Malaysian neonates (92 Malays, 96 Chinese and 74 Indians) was quantitatively determined by the World Health Organisation method. Analysis of variance for the levels of G6PD enzyme activity by ethnic origin and sex showed that there was a significant difference between mean levels of enzyme activity in the three ethnic groups (P = 0.03) but no difference between the sexes (P = 0.36). Multiple range analysis showed that Malays had significantly higher mean levels of G6PD enzyme activity than those of Chinese (P = 0.01). There was no significant difference between the mean levels of G6PD enzyme activity of Chinese and Indians (P = 0.52), nor was there any difference between those of Malays and Indians (P = 0.08). The difference in levels of G6PD enzyme activity among the different ethnic groups could be due to the existence of different G6PD variants.

Matched MeSH terms: India/ethnology

Cephalometric ideals in Chinese, Malay and Indian ethnic groups

Lew KK

Asian J Aesthet Dent, 1994;2(1):35-8.

PMID: 9063112

Cephalometric data from 105 female subjects (35 Chinese, 35 Malay and 35 Indian) with good occlusion and aesthetic pleasing facial profiles (determined by a trained clinician and endorsed by the lay public) were analysed using the Steiner analysis. Statistical analysis of the data showed that while the cephalometric ideals of the Chinese and the Malay ethnic groups were rather similar, cephalometric differences existed between the Chinese and Indians as well as the Malays and Indians. Compared to the Chinese and Malays, the Indians appeared to have less prognathic mandibles and maxillae, less protrusive and proclined upper and lower incisors and also less protrusive upper and lower lips. These differences demonstrate intrinsic ethnic differences and emphasize the need to treat patients of different ethnic groups using cephalometric norms which are peculiar to their own group.

Matched MeSH terms: India/ethnology

Risk factors for accidental poisoning in urban Malaysian children

Azizi BH, Zulkifli HI, Kasim MS

Ann Trop Paediatr, 1993;13(2):183-8.

PMID: 7687115

In a case control study, 70 children consecutively hospitalized for acute ingestion of poisons were compared with 140 other hospitalized children matched for age. Children aged less than 3 years and boys were most often the victims. Univariate analysis identified Indian race, having a parent younger than 21 years, residing at present address for less than 1 year and living in a household with more than five occupants as significant risk factors. Experience of a recent stressful event in the family barely failed to reach the level of significance. Logistic regression analysis confirmed that Indian race, having a parent younger than 21 years and residing less than 1 year at the present address were independent predictors of acute poisoning. Positive interactions were noted between Indian race and duration of residence and between parental age and duration of residence. Knowledge of risk factors and their interactions may be useful in planning preventive measures against childhood poisoning.

Matched MeSH terms: India/ethnology

Clinical patterns of X linked agammaglobulinemia in Malaysian children

Noh LM, Ismail Z, Zainudin BM, Low SM, Azizi BH, Noah RM, et al.

Acta Paediatr Jpn, 1995 Jun;37(3):331-5.

PMID: 7645382

X linked agammaglobulinemia (XLA) is rarely reported from developing countries especially from South East Asia. It appears that X linked agammaglobulinemia is less common in certain ethnic groups. It is very uncommon in black people in USA and South Africa. In multiracial Malaysia we have documented five XLA in Malays and Indians but not in the Chinese that constitute about 31% of the population. First degree relatives afflicted with XLA or other primary immunodeficiencies occurred more often in our study. All showed lung involvement although the etiologic organisms involved were atypical, being Gram negative.

Matched MeSH terms: India/ethnology

Impact of cyclosporine dose on renal allograft function in an Asian population

Vathsala A, Lee WT, Lim CH

Transplant Proc, 1994 Oct;26(5):2507-8.

PMID: 7940768

Matched MeSH terms: India/ethnology

Fulltext Circumstances surrounding accidental poisoning in children

Azizi BH, Zulkifli HI, Kassim MS

Med J Malaysia, 1994 Jun;49(2):132-7.

PMID: 8090091

Circumstances surrounding accidental ingestion of poisons were investigated in families of 70 hospitalised children. Indian children were more likely to be hospitalised for poisoning. Poor safety measures directly contributed to poisoning incidents. Poisons had not been stored safely and only in 12.9 per cent of families were the poisons allegedly kept in cupboards. Kerosene had been ingested from soft drink containers in 70 per cent of instances. Medications had been taken mainly from plastic envelopes (57.9%) or bottles (31.6%). Safety practices in the homes of cases and 140 controls were compared. As a whole parents of victims had poor safety practices when compared with parents of controls. Poisoning incidents were discovered by mothers in 75.0 per cent of the cases. Vomiting was induced by parents in 32.3 per cent of cases involving medications and non-volatile items, and in 41.6 per cent of kerosene ingestions. Before hospitalisation 59.4 per cent were brought to general practitioners and 22.7 per cent to government clinics. Mothers were the main attendants when children were brought for medical care. This study highlights the need for measures to prevent childhood poisoning and reduce its morbidity. Household products and medications should be made safer to children through improved packaging, prescribing instructions and education. Safety and first aid education may be directed towards parents, particularly mothers, through the media and health facilities.

Matched MeSH terms: India/ethnology

Atopic eczema in a multiracial country (Malaysia)

Jaafar RB, Pettit JH

Clin Exp Dermatol, 1993 Nov;18(6):496-9.

PMID: 8252784

A total of 14,342 patients with skin diseases who had attended either the National University of Malaysia skin clinic or a private dermatological office were analysed. Five hundred and thirty-four cases (3.7%) had atopic eczema, the prevalence being highest among the Malays (4.3%). The prevalence of atopic eczema among clinic attenders is lower in all three major Malaysian races when compared with studies from England.

Matched MeSH terms: India/ethnology

Coronary artery disease in Asians

Rajadurai J, Arokiasamy J, Pasamanickam K, Shatar A, Mei Lin O

Aust N Z J Med, 1992 Aug;22(4):345-8.

PMID: 1445022

From available studies, there appears to be a racial preponderance of coronary artery disease (CAD) among Indians when compared to other ethnic groups. We found that this racial difference exists even in a young Asian population with premature atherosclerosis. In this small series, these racial differences could not be explained by the commonly known risk factors for coronary artery disease--smoking, hypertension, diabetes and hypercholesterolaemia, findings similar to those found in older patients elsewhere. Only fasting triglyceride levels were significantly higher among young Indians compared to non Indians (p less than 0.02) although the importance of this finding as a risk factor for CAD remains controversial. The majority of these young patients were treated medically and their one year survival was good.

Matched MeSH terms: India/ethnology

Cross-cultural variations in dental knowledge among antenatal mothers

Esa R, Razak IA, Jalalludin RL

Odontostomatol Trop, 1992 Mar;15(1):19-23.

PMID: 1287607

This study evaluates the level of dental knowledge among 328 antenatal mothers from different ethnic groups and ascertains the importance of the various sources of dental information. The mothers were interviewed based on a structured questionnaire. Most mothers knew about the number of sets of teeth they possessed throughout their life. This was most evident among the Chinese and least among the Malays. Only 42.7% of the mothers interviewed were positive about the preservation of their teeth throughout life. This belief was highest among the Chinese followed by the Indians. However about 40% of the Chinese believed that tooth decay is hereditary. Generally the principal sources of dental information cited by most mothers were television or radio followed by dentists, school and family. This order of importance was similarly observed among the Malays and Chinese. However, among Indians, family members represent the second most important source of dental information. The implications of these findings are discussed.

Matched MeSH terms: India/ethnology

Lung function reference values in Singaporean children aged 6-18 years

Connett GJ, Quak SH, Wong ML, Teo J, Lee BW

Thorax, 1994 Sep;49(9):901-5.

PMID: 7940431

A study was undertaken to produce reference values of lung function in Chinese children and a means of calculating adjusted standard deviation scores of lung function for Malay and Indian ethnic groups.

Matched MeSH terms: India/ethnology

Fulltext Rheumatic heart disease in Malaysia

Jamal F, Mohd Salleh H, Tan SP

World Health Forum, 1994;15(1):56-7.

PMID: 8141979

Matched MeSH terms: India/ethnology

Lipid profiles in healthy fertile Singaporean women

Loke DF, Viegas OA, Ratnam SS

Gynecol. Obstet. Invest., 1993;36(2):108-13.

PMID: 8225044

Serum lipid profiles were studied in 167 healthy fertile Singaporean women, aged between 18 and 40 and comprising 114 Chinese, 28 Malays and 25 Indians. Parity or ethnic differences did not affect lipid concentrations. Except for triglycerides which showed a decreasing trend, there was no significant variation in lipid concentrations with age. However, all lipid concentrations except HDL cholesterol (which decreased) appeared to increase with body mass index. Compared with other populations, these Singaporean women appeared to have higher mean concentrations of total cholesterol and lower mean concentrations of HDL cholesterol. The possibility that these differences could have contributed to the increasing incidence of coronary heart disease in Singapore is discussed.

Matched MeSH terms: India/ethnology

Fulltext Morbidity and mortality of infants of diabetic mothers born at the Maternity Hospital, Kuala Lumpur

Boo NY

Med J Malaysia, 1992 Mar;47(1):56-9.

PMID: 1387451

A prospective study was carried out in the Maternity Hospital, Kuala Lumpur in 1989 to determine the morbidity and mortality of infants of diabetic mothers. Out of 24,856 neonates born during the study period, 54 neonates (2.2 per 1000 livebirths) were born to mothers who were diagnosed to have diabetes mellitus before the current pregnancy or who had impaired glucose tolerance test during the current pregnancy. Almost a third (29.6 percent) of these infants of diabetic mothers had birthweight of 4000 grams and above, and 37.0 percent of the 54 babies were large-for-gestational age. Hypoglycemia occurred in 9/54 (16.7 percent) of the neonates, respiratory distress syndrome in 5/54 (9.3 percent), shoulder dystocia in 7/54 (13.0 percent), and congenital abnormalities in 4/54 (7.4 percent). Three (5.6 percent) neonates died during the neonatal period. The results of this study suggest a need to intensify control of maternal diabetes mellitus during pregnancy in order to reduce the rates of morbidity and mortality of their infants.

Matched MeSH terms: India/ethnology

Fulltext Family characteristics of suicides in Cameron Highlands: a controlled study

Maniam T

Med J Malaysia, 1994 Sep;49(3):247-51.

PMID: 7845274

Cameron Highlands has one of the highest suicide rates in the world, especially among Indians. Forty Indian families (19 suicides; 21 controls) were studied to compare family characteristics such as income, overcrowding, birth order of index cases of suicide, family history of suicidal behaviour or mental illness, marital disharmony, presence of alcohol abuse, availability of, and knowledge about, weedicides/insecticides, talk/threat of suicide among family members and experience of significant losses in the past year. Controls were matched for age, sex and educational level with the index cases of suicide. A significant difference was only found for one of the above factors, namely increased experience of significant losses in the past year in the family of index cases of suicide. More than 75% in both groups had alcohol related problems. About equal proportions in each group had a family history of suicidal behaviour and mental illness. There was more marital disharmony in families of suicides but this failed to reach significance. These results and methodological limitations of this study are discussed.

Matched MeSH terms: India/ethnology

Fulltext The role of prophylactic antibiotics in caesarean section--a randomised trial

Ng NK, Sivalingam N

Med J Malaysia, 1992 Dec;47(4):273-9.

PMID: 1303479

A prospective randomised controlled study was conducted over a 6 month period on the value of administering prophylactic antibiotics in patients undergoing emergency caesarean section at the Ipoh General Hospital. A total of 222 patients were randomised to receive 24 hours of ampicillin (500 mg per dose), cefoperazone (1 gm per dose) or no antibiotics. In all parameters of patient morbidity, the group receiving cefoperazone showed significantly better results as compared to the group not receiving antibiotics. The ampicillin group also had favourable results but generally not achieving statistical significance. Prophylactic antibiotics appear to be beneficial and consideration should be given to make it a routine in all emergency caesarean sections.

Matched MeSH terms: India/ethnology

Assessment of skin types, skin colours and cutaneous responses to ultraviolet radiation in an Asian population

Wee LK, Chong TK, Quee DK

Photodermatol Photoimmunol Photomed, 1997 Oct-Dec;13(5-6):169-72.

PMID: 9542751

Ninety normal individuals were included in this study on skin types, skin colours and cutaneous responses to ultraviolet radiation. Skin types were recorded using Fitzpatrick's classification, skin colours were measured using the Minolta Chromameter CR-300, and cutaneous responses to UV radiation were measured in terms of minimal erythema dose (MED) to UVA, UVB and the immediate pigment darkening dose to UVA (IPDDA). Skin colour measurements were taken from the right cheek to represent facultative skin colours, and from the buttock to represent constitutive skin colours. The colours measured were expressed by the L x a x b colour space. Skin types and some colour parameters (L and b from covered parts of body) correlated fairly well with the minimal erythema doses (MED) to UVA and UVB. Skin colour measurements are more objective than skin type assessment and could be better markers of photosensitivity. However, there is still considerable overlap in MEDs for persons with different skin colours, and further studies of these parameters are warranted. Our MEDs are higher than other reports on similar skin types and skin colours. This could be due to differences in methodology, genetic make-up or acclimatization from chronic sun exposure. This illustrates the importance of local controls for each institution dealing with photosensitive disorders.

Matched MeSH terms: India/ethnology

Breastfeeding at 6 weeks and predictive factors

Chye JK, Zain Z, Lim WL, Lim CT

J Trop Pediatr, 1997 10;43(5):287-92.

PMID: 9364127 DOI: 10.1093/tropej/43.5.287

Despite the numerous changes made in accordance with the Baby Friendly Hospital Initiative at the University Hospital, Kuala Lumpur, the low rates of breastfeeding have persisted. This study aims to examine the current trend in infant feeding, and the influences of some perinatal and sociodemographic factors on breastfeeding. Five-hundred mothers with singleton pregnancies and healthy infants were interviewed at 6 weeks post-partum. Only 124 (25 per cent) mothers were practising exclusive breastfeeding (EBF), and 132 (26 per cent) mothers were using exclusive infant formula feeding (EIF). On logistic regression analyses, mothers who followed EBF were more likely to have had antenatal plans to breastfeed (Odds ratio 2.44, 95 per cent confidence interval 1.75-3.45), not in paid employment post-natally (OR 1.76, 95 per cent CI 1.31-2.36), of older age group (> 27 years) (OR 1.48, 95 per cent CI 1.13-1.93), had female infants (OR 1.38, 95 per cent CI 1.05-1.80) and of Indian ethnicity (compared to Chinese) (OR 3.87, 95 per cent CI 2.16-6.89). Breastfeeding difficulties were associated with decreased odds of EBF (OR 0.21, 95 per cent CI 0.13-0.34). Parental education, fathers' ages and incomes, primigravida status, Caesarean section, present of episiotomy, late first breastfeed, phototherapy, and length of hospital stay were not significant predictors of failure of EBF. In comparison, predictive factors for increased use of EIF were mothers who have had breastfeeding difficulties, < or = 9 years of schooling, and of Chinese descent. In conclusions, the overall rate of EBF by 6 weeks of age in infants born in this urban hospital had remained poor. The adverse factors for EBF identified in this study warrant further in-depth studies to determine effective ways of improving EBF rates.

Matched MeSH terms: India/ethnology

Incidence of postnatal depression in Malaysian women

Kit LK, Janet G, Jegasothy R

J Obstet Gynaecol Res, 1997 Feb;23(1):85-9.

PMID: 9094824

OBJECTIVE: To determine the incidence of postnatal depression of Malaysias women at 6 week postpartum and a survey of their sociocultural practices.

METHODS: A hundred and fifty-four women who were 6 weeks postpartum attending the postnatal clinic between May and July 1995 at Maternal and Child Health Clinic, Seremban, Malaysia. Maternal socio-demography, depression by Edinburgh Postnatal Depression Scale (EPDS), postnatal care and practices e.g. pantang larang (prohibited behaviour and practices), diet and partnering were evaluated.

RESULTS: Postnatal depression was 3.9%. Indians had the highest rate at 8.5% as compared to Malays (3.0%) and none in Chinese (p < 0.05). There were no demographic differences in the study groups. Average score of EPDS was 4.05 which ranged from 0 to 20. During the confinement 85.7% of women took special diet; 64.3% followed pantang larang and 78.8% had someone to look after them. The incidence of postnatal depression is low in Malaysia at 3.9%. Majority of Malaysian women still observed the traditional postnatal beliefs and practices.

Matched MeSH terms: India/ethnology

Fulltext Drinking habits of Malaysians in general practice

Maniam T

Med J Malaysia, 1994 Dec;49(4):369-74.

PMID: 7674973

Five hundred and sixty-two consecutive attenders at an urban general practice were studied using the Consumption Index which has been successfully used in a general hospital sample. Seventy per cent of Chinese, 11% of Malays and 42% of Indians have used or are currently using alcohol-a vast majority of them were social drinkers. Among those who ever drank, 6% of Chinese and 22% of Malays drank more than 14 units per week. The hypotheses that more Indians used alcohol and used it more heavily were not supported in this urban sample. Possible explanations for these findings and the limitations of this study are discussed.

Matched MeSH terms: India/ethnology

Fulltext A comparative study of branch retinal vein occlusion and central vein occlusion amongst Malaysian patients

Teoh SL, Amarjeet K

Med J Malaysia, 1993 Dec;48(4):410-5.

PMID: 8183164

A retrospective study of 95 patients with retinal vein occlusion was carried out to determine the clinical presentation and pattern of distribution in the local Malaysian population. There was no significant difference found in its distribution with regards to sex. In comparing branch retinal vein occlusion with central retinal vein occlusion, no significant differences were found in its racial distribution. Branch retinal vein occlusion occurred more commonly among the older patients whereas the converse is true for central retinal vein occlusion. Reduced vision represents the commonest mode of presentation. Hypertension, diabetes mellitus, hyperlipidaemia and haematological disorders are important associated systemic conditions.

Matched MeSH terms: India/ethnology

Displaying publications 261 - 280 of 956 in total