Displaying publications 3261 - 3280 of 55738 in total

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  1. Ullah MA, Islam MT, Alam T, Ashraf FB
    Sensors (Basel), 2018 Dec 01;18(12).
    PMID: 30513719 DOI: 10.3390/s18124214
    This paper demonstrates the performance of a potential design of a paper substrate-based flexible antenna for intrabody telemedicine systems in the 2.4 GHz industrial, scientific, and medical radio (ISM) bands. The antenna was fabricated using 0.54 mm thick flexible photo paper and 0.03 mm copper strips as radiating elements. Design and performance analyses of the antenna were performed using Computer Simulation Technology (CST) Microwave Studio software. The antenna performances were investigated based on the reflection coefficient in normal and bent conditions. The total dimensions of the proposed antenna are 40 × 35 × 0.6 mm³. The antenna operates at 2.33⁻2.53 GHz in the normal condition. More than an 8% fractional bandwidth is expressed by the antenna. Computational analysis was performed at different flexible curvatures by bending the antenna. The minimum fractional bandwidth deviation is 5.04% and the maximum is 24.97%. Moreover, it was mounted on a homogeneous phantom muscle and a four-layer human tissue phantom. Up to a 70% radiation efficiency with a 2 dB gain was achieved by the antenna. Finally, the performance of the antenna with a homogeneous phantom muscle was measured and found reliable for wearable telemedicine applications.
    Matched MeSH terms: Humans
  2. Sinha NK, Bhardwaj A
    Clin Orthop Surg, 2019 12;11(4):495.
    PMID: 31788175 DOI: 10.4055/cios.2019.11.4.495
    Matched MeSH terms: Humans
  3. Ganesananthan S, Rajvinder S, Anil R, Kiew KK, Ng KL, Rosaida MS, et al.
    Med J Malaysia, 2004;59 Suppl C:48.
    Background: Achalasia cardia is an uncommon disease that is often detected late and is associated with significant morbidity. It is a primary esophageal motility disorder diagnosed based on a good history, barium swallow, upper endoscopy and a standard esophageal manometry.
    Materials and Methods: We reviewed complete available records of treatment naïve patients with achalasia cardia from 1st January 2000 till April 2004.
    Results: A total of 40 patients, with average presenting age at 44±16 (range 19-73) years with 14 males: 26 females with 20 Malays: 15 Chinese: 5 Indians, were suitable for further analysis. The classical symptom of dysphagia to liquids and solids were noted in all cases (100%). These patients learnt that water and sometimes-aerated drinks aid in flushing food down. Symptoms of regurgitation (36 patients-90%), heartburn (15 patients-37.5%), weight loss (10 patients–25%), nocturnal cough (16 patient-40%), retrosternal chest discomfort (2 patient-5%) and hemetemesis (2 patient-5%) was noted. One patient had aspiration pneumonia and another had concomitant active pulmonary tuberculosis and 8 had concomitant constipation (20%). In this series the duration of illness before diagnosis was 5±6 (range
    0.3- 30) years and their presenting weight was 53±13 (range 33-82) kg. Barium swallow diagnosed achalasia in 27 patients (67.5%) and a dysmotility disorder in 7 cases (17.5%). There were 10 patients with mega-esophagus and two had epiphrenic diverticulum. There was no pseudoachalasia. Standard esophageal manometry, performed in 36 cases, demonstrated aperistalsis with one vigorous achalasia. The manometric assembly failed to pass through the sphincter in 14 cases and hence LOS assessment was not possible. Four cases demonstrated normal LOS pressure but demonstrated incomplete relaxation (normotensive achalasia). Pneumatic dilatation was performed in 38 newly cases without any complications with excellent symptomatic relief and a 3-12 month post procedural weight gain of 7±5 (range: 0-19) kg. Six patients required a second dilatation and another required two further dilatation. The durability of the total 45 pneumatic dilatations during this short study period was excellent at 24±12 (range 2-48) months.
    Conclusion: A primary esophageal motility disorder must be excluded in any patients who present with dysphagia, with or without regurgitation and a "normal" upper endoscopy. Achalasia is not uncommon, often delayed in diagnosis and has a varied presentation. Although there is no cure for achalasia, but early detection and treatment certainly relieves symptoms and prevents complications. Pneumatic dilatation in our center has excellent durability without any complications.
    Matched MeSH terms: Humans
  4. Ganesananthan S, Kew ST, Ngau YY, Ong J, Matvinder S, Liew SH, et al.
    Med J Malaysia, 2001;56 Suppl A:47.
    Matched MeSH terms: Humans
  5. Linnell RM
    Lancet, 1914;184:127-8.
    DOI: 10.1016/S0140-6736(01)19747-3
    Matched MeSH terms: Humans
  6. Keith RD
    Lancet, 1913;182:1117-8.
    DOI: 10.1016/S0140-6736(01)79352-X
    Matched MeSH terms: Humans
  7. Woodward TE, Smadel JE, Ley HL, Green R, Mankikar DS
    Ann Intern Med, 1948;29:131-4.
    DOI: 10.7326/0003-4819-29-1-131
    A NEW antibiotic Chloromycetin has been clinically tested in the treatment of typhoid fever and has been found to exhibit significant chemotherapeutic effects. A description of the results in 10 cases is submitted as a preliminary report.
    Matched MeSH terms: Humans
  8. Dawson A, Rashid A, Shuib R, Wickramage K, Budiharsana M, Hidayana IM, et al.
    Aust N Z J Public Health, 2020 Feb;44(1):8-10.
    PMID: 31825567 DOI: 10.1111/1753-6405.12956
    Matched MeSH terms: Humans
  9. Maisarah AS, Nurul Ajilah MK, Siti Amalina MR, Norazuroh MN
    This literature review focuses on the implementation of biomedical ethics in Malaysia based on the government and institutional settings. Insights of the development of biomedical ethics and the responsible entities, particularly the clinical trials that become the emerging field of interest by the government to boost the biomedical research in Malaysia are provided. Some issues and their implications for research and ethical review process in Malaysia are also elucidated. The review indicates the advancement of policies by the government in implementing the biomedical ethics with some affairs that should be a matter to be concerned.
    Keywords: Biomedical, ethics, implementation, standards, research ethic committee, good laboratory practice.
    Matched MeSH terms: Humans
  10. Citation:
    Ethical Professional Practice Guidelines. Kuala Lumpur: Academy of Medicine Malaysia; 2016
    Matched MeSH terms: Humans
  11. Pyvovar SM, Rudyk IS, Kopytsya MP, Lozyk TV, Galchinskaya VY, Bondar TM
    Pol Merkur Lekarski, 2019 Nov 29;47(281):170-176.
    PMID: 31812970
    The course of heart failure (HF) and its progression is associated with comorbidities, genetic factors and a dynamics of a number of biomarkers. The low triiodothyronine syndrome (LT3S) is observed in some patients with HF. Extremely little data are available in the literature regarding the effect of β-adrenoreceptors (β-AR) genes polymorphisms on the development of LT3S and many contradictory results about their association with HF course. This encourages new research in this area.

    AIM: The aim of study was to evaluate the relationship of β-adrenergic receptors gene polymorphisms with low triiodothyronine syndrome in patients with a heart failure.

    MATERIALS AND METHODS: 354 patients with HF on a background of postinfarction cardiosclerosis were included to the study. At 89 (25.1%) patients LT3S was diagnosed. The course of HF was studied for 2 years. Mean levels of thyroid stimulating hormone (TSH), free T3f and T4f were evaluated. Genotyping of 4 single nucleotide polymorphisms (Gly389Arg of β1-AR gene, Ser49Gly of β1-AR gene, Gln27Glu of β2- AR gene and Ser275 of GNβ3 gene) was performed by polymerase chain reaction. Genetic and epidemiological analysis was performed using the SNPStats program.

    RESULTS: The risk of LT3S in patients with HF increases with homozygous G/G variant of Gln27Glu polymorphism of the β2-AR gene (OR=2.21, p=0.037), described as a recessive model of inheritance. There was a tendency to increase the risk of LT3S development in the presence of the genotype C/T of the Ser275 polymorphism of the GNb3 gene (OR=1.75, p=0.054), described as an over-dominant model. The genotype C/G of the Gln27Glu polymorphism of the β2-AR gene was associated with a decreased risk of LT3S development (OR=0.54, p=0.037), described as over-dominant model. Patients with HF carriers the A allele (A/GA/A) of the Ser49Gly polymorphism of the β1-AR gene have a lower risk of repeated hospitalization due to HF decompensation (OR=0.50, p=0.032), described as a dominant model. There was a tendency to increase the risk of re-hospitalization in the G-allele (C/GG/ G) variant of the Gln27Glu polymorphism of the β2-AR gene (OR=1.68, p=0.057), described as a dominant heredity model. At patients with HF in combination with LT3S the risk of re-hospitalization increases at C/G variant of the Gln27Glu polymorphism of β2-AR gene (OR=1.25, p=0.025), described as an over-dominant model.

    CONCLUSIONS: The results suggest that congenital genetic alterations in β-adrenergic pathways may be associated with the development of LT3S in patients with HF and the features of the HF course.

    Matched MeSH terms: Humans
  12. Mustapha MS
    Adequate consumption of Omega-3 fatty acids are essential during pregnancy because they play an important role in the development offetal brain and retina. The rate of growth remains high during the first year of life. Omega-3 is converted inside the body into longer chain polyunsaturated fatty acids docosahexanoic acid (DHA) and eicosapentaenoic acid (EPA). DHA and EPA are primarily derived from fish and algae. DHA is essential for the growth and functional development of the brain in infants. DHA is also required for the maintenance of normal brain function in adults. The inclusion of adequate amount of DHA in the diet improved learning ability, whereas deficiencies of DHA are associated with deficits in learning. DHA is readily taken up by the brain in preference to other fatty acids. The turnover of DHA in the brain is very fast, more so than is generally realized. The visual acuity of healthy, full-term, formula-fed infants is increased when their formula includes DHA. However, health professionals and the general public in Malaysia may not be aware about the importance, sources or the quantities required for these essential fat components in foods. This review discusses the benefits of omega-3 consumption with particular emphasis during pregnancy and the first year of life. This review will also attempt to discuss sources of omega-3 fatty acids in Malaysia with the aim to achieve the recommended nutrient intakes foromega-3 fatty acids.
    Keywords: Omega 3 fatty acids, Lactation in Pregnancy, Sources of Omega-3 FA
    Matched MeSH terms: Humans
  13. Tan YM, Chan SG
    Caring behaviours presented by the nurses while providing care is the essence of nursing. However, operation theatre nurses must also adhere to the nursing value in social sciences and humanities to address the patient's needs. The concern of the nurses should not only be for the basic life sustaining needs but also for physiological, psychological, socio cultural and spiritual dimension ofpatient's human responses. The purposes of this study were to determine the perception regarding caring behaviours and the level of caring among the Operation theatre nurses in Hospital Universiti Sains Malaysia. In addition, there were associations when the determination between demographic variables like genders and years of experience of the nurses in relation to their caring behaviours is necessary. It isa quantitative, descriptive survey design and 95 nurses participated in the study. The revised Wolfs Caring Behaviours Inventory was used to measure the dimensions of caring. "Professional knowledge and skill" was identified to be the highest among the five dimensions of caring that was being measured. Findings show that the nurses demonstrated a high level of caring behaviours during their course of work. However, none of the demographic factors studied were significantly associated to their caring behaviours.
    Keywords: Caring attitudes, Caring behaviours, Dimensions of caring
    Matched MeSH terms: Humans
  14. Lai PK, Lim PH
    The evolution of nursing profession and education has taken its pace over the past years. Therefore, with the changes in nursing education over the years, the level of professional socialization among the students has become an area of interest. The objectives of this pilot study were to explore and compare the level of professional socialization between the diploma and degree nursing students (first year and final year) using the measuring tool of NPVS-R as well as to identify the demographic variables related to the level of professional socialization among the nursing students. From this pilot study, it was found that there was no significant difference in the level of professional socialization between the diploma and degree nursing students (p = 0.133). With regards to the demographic variables related to the level of professional socialization, significant difference was found only for the variable of father's educational level (p = 0 .035).
    Keywords: Professional Socialization, Diploma and Degree Nursing Students, Nursing Education
    Matched MeSH terms: Humans
  15. Leong SW, Chan SG
    Clinical practice is an essential component of the nursing student's training. The practice allows nursing students the opportunity to relate theory into practice during nursing care to the patients. The aim of this project was to determine perceptions of clinical placement experience with respect to clinical practice, enhancement of learning and hindrance among nursing students. A total 254 participants undergoing training at Nursing College Kubang Kerian participated in this project. They were selected using the Raosoft sample size calculator. Survey questionnaires were distributed to 80 participants from first year, 88 from second year and 86 participants from third year. The questionnaire consisting of 25 items with 5-point Likert Scale responses was used to measure nursing students' perceptions towards nurses during their clinical placement experience. In addition, demographic factors such as age groups, ethnicity, educational levels and years of training were examined. The items were pilot-tested and the Cronbach Alpha values obtained for clinical practice, enhancement of learning and hindrance consisting of 0.80, 0.80 and 0.83 respectively. The final data was analysed using both descriptive and inferential statistics. Non-parametric Kruskal Wallis was used to make comparisons where sub samples were imbalanced. The level of significance was set at 0.05. The results indicate that nursing students perceived their clinical placement positively. Perceptions towards clinical practice were significantly different between nurses based on their residential areas and years of training. The results of this study revealed that there were challenges for the nursing educators, clinical instructors and other health providers in achieving a supportive clinical environment for the nursing students.
    Keywords: Nursing, Clinical Placement, , Clinical Practice, Enhancement or Hindrance in learning
    Matched MeSH terms: Humans
  16. Dougall D, Abraham EP
    Nature, 1955;176:256.
    DOI: 10.1038/176256a0
    WHILE studying the antibacterial products of a species of Streptomyces (N.C.I.B. 8697) sent by Dr. R. Green from Malaya, we have isolated an orange-red coloured basic substance which is very active against a variety of bacteria and is highly toxic to mice. The antibiotic was extracted from the culture fluid into chloroform, at pH 6, and re-extracted into water at pH 2, or extracted into trichloroethylene, at pH 8.5, and re-extracted into water at pH 3.5. It was purified by counter-current distribution in a solvent system consisting of trichloroethylene and 0.1 M sodium citrate buffer, pH. 5.95. In this system its partition coefficient, K (Combining double low line concentration in trichloroethylene/concentration in water), was 0.98. The purified product yielded a crystalline hydrochloride, reineckate and picrate. The behaviour of this antibiotic suggests that it is identical with, or very closely related to, xanthomycin A - a substance which has been isolated from species of Streptomyces1, and stated to have quinonoid properties2. We wish to record, however, that it is a stronger base than xanthomycin A has been reported to be and that it yields two simple bases on hydrolysis which have not been described as degradation products of xanthomycin A. © 1955 Nature Publishing Group.
    Matched MeSH terms: Humans
  17. Smadel JE, Bailey CA, Diercks FH
    Am J Hyg, 1950;51:229-41.
    DOI: 10.1093/oxfordjournals.aje.a119387
    Two field trials were conducted in Malaya in which 75 volunteers were exposed in hyperendemic areas of scrub typhus. Thirty-four of these individuals received chloromycetin prophylactically for a total period of 3 weeks during and following exposure. They did not show clinical evidence of scrub typhus throughout the period of prophylaxis or the ensuing 5 days. However, scrub typhus developed in 15 volunteers in the prophylactic groups of the two trials 5 to 14 days after drug was discontinued. Although the attack rate among the volunteers in the two field trials varied markedly, there was no essential difference in the ultimate infection rates among the controls and those given prophylaxis in each test. Scrub typhus when it developed among volunteers in the prophylactic group was not significantly different from the disease in the controls except for the absence of eschar formation. Relapses were prominent features of the disease in the volunteers of both prophylactic and control groups. These had not been observed previously in untreated cases of scrub typhus or in naturally occurring cases which were treated with chloromycetin. Fifty-four per cent of the 37 persons in the two trials who contracted scrub typhus suffered one or more relapses. Various factors probably contributed to this phenomenon but the opinion is that the short course of chloromycetin therapy given very early in the illness probably was an important factor. Ten volunteers had received experimental scrub typhus vaccine during earlier investigations because of possible exposure to infection. The vaccination did not influence the incidence of infection or the course of the disease in those persons developing scrub typhus. Prolonged administration of chloromycetin as a prophylactic measure and its use in the treatment of the initial attacks of scrub typhus, as well as the relapses, indicated that the drug is of low toxicity for man, and that drug fast strains of Rickettsia tsutsugamushi are not readily produced.
    Matched MeSH terms: Humans
  18. Balakrishnan S, Hussein HB
    PMID: 585738
    Matched MeSH terms: Humans
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