MyMedR

Fulltext Reimplantation of an Extruded Femoral Segment After Gamma Sterilization in A Type IIIA Supracondylar Femur Fracture: A Case Report

Aizah N, Su Y, Shaifulnizam C, MRos M

Malays Orthop J, 2014 Jul;8(2):66-8.

PMID: 25279099 MyJurnal DOI: 10.5704/MOJ.1407.015

Extruded bone is a rare complication of high energy open fractures, and there is only a handful of literature on reimplantation of the extruded segment. No clear guidelines exist regarding timing of reimplantation, stabilization of extruded bone segments, and also bone disinfection and sterilization techniques. Previous reports describe sterilization using thermal or chemical methods. We present a case of successful reimplantation of an extruded metaphyseal segment of femur after gamma sterilization in a fourteen- year old boy.

Matched MeSH terms: Adolescent

Variable clinical phenotypes in a family with homozygous c.1159G>A mutation in the thyroid peroxidase gene

Lee CC, Harun F, Jalaludin MY, Heh CH, Othman R, Kang IN, et al.

Horm Res Paediatr, 2014;81(5):356-60.

PMID: 24717978 DOI: 10.1159/000359922

Defects in the thyroid peroxidase (TPO) gene have been associated with goitrous congenital hypothyroidism (CH).

Matched MeSH terms: Adolescent

Cigarette smoking and the influencing factors among adolescents in a secondary school in Malaysia

Santhna LP, Khalid Z, Selamat S, Ho SE, Mat S

Clin Ter, 2013;164(6):507-12.

PMID: 24424214 DOI: 10.7417/CT.2013.1628

BACKGROUND: Smoking has always been a huge problem in Malaysia and its surrounding nations. The purpose of this study was to determine the prevalence of cigarette smoking and to identify the influencing factors associated with smoking habits among adolescents.

MATERIALS AND METHODS: This cross-sectional study was carried out on 226 respondents, using a questionnaire which had 4 sections: socio-demographic data, personal information, family information and social information. Data was analyzed using SPSS® version 16. For categorical variables, comparisons were made using Chi-square and for numerical variables a t-test was performed.

RESULTS: The current smoker prevalence rate was 20.8% which showed a significant association between smoking and individual factors: level of knowledge on the effects of smoking (p < 0.05), significant association was seen between smoking and marital status of parents, smoking status of male siblings and various other aspects of the individuals themselves.

CONCLUSIONS: Concerted efforts involving various parties should be taken to curb or prevent this problem or the number of teenage smokers in the country will increase. This in the long run will invite problems to the well being of the adolescents themselves, their families, community and the nation as a whole.

Matched MeSH terms: Adolescent

Fulltext The quality of life in hearing impaired adolescents after hearing aid application

Mohd Adibi SMA, Chen NR, Azmir NA, Solahan N, Ismail A, Anuar AZ, et al.

Med J Malaysia, 2013 Aug;68(4):315-22.

PMID: 24145259 MyJurnal

Hearing impairment in adolescents is a major public health problem. According to the World Health Organization (WHO) deafness and hearing impairment are common health problems throughout the world. Hearing impairment generally impairs emotional, social, communication and educational function. The aim of this study was to determine the correlation between duration of hearing aid use and improvements in the quality of life. The cross sectional study was conducted at Jalan Peel Primary Special School and Universiti Kebangsaan Malaysia Medical Center (UKMMC) from July 2010 until June 2011. A total of 21 students with hearing impairment involved in this study with mean age of 12.57 (10 to 19 years old). The subjects were divided into 2 groups: first-time hearing aid users and long standing hearing aid users. The hearing assessment was conducted in the first group and hearing aids were fitted. After 1 month hearing aid fitting, the questionnaires were distributed to both groups. Statistical analysis had showed no relation (p>0.05) between duration of hearing aid use and the improvement in the quality of life. However, regardless of the duration of hearing aid usage, there was improvement in the quality of life as shown by the scores of the questionnaires. In conclusion there was no significant relation between duration of hearing aid use and the improvement in the quality of life. Hearing aids were beneficial for hearing loss students regardless of the duration of the hearing aid usage.

Matched MeSH terms: Adolescent

Fulltext Single-center experience of von Willebrand disease (vWD) among patients with menorrhagia: a diagnosis which could be missed

Hassan R, Yusof WA, Hussain NH, Abdullah WZ

Indian J Hematol Blood Transfus, 2012 Sep;28(3):157-61.

PMID: 23997452 DOI: 10.1007/s12288-011-0135-6

Menorrhagia is one of the gynecological complaints, seen in women of reproductive age. In majority of cases no organic pathology is found. To date there is no consensus on application of von Willebrand disease (vWD) testing as part of the routine investigations in menorrhagia. Diagnosis of vWD is challenging. It is complicated by intra-individual variations in von Willebrand antigen, activity, and factor VIII levels due to fluctuation of these factor levels during the menstrual cycle or hormonal therapy. The aim of this study is to detect vWD presenting with menorrhagia among Malays attending gynecology clinic by using a standard panel of haemostatic profiles. Thirty Malay patients attending gynecology clinic with unexplained menorrhagia were included in this study. Haemostatic profile such as platelet count, prothrombin time, activated partial thromboplastin time (APTT), factor VIII assay, von Willebrand factor antigen, and von Willebrand factor activity, and collagen binding assay were measured in all patients. Pre- and post hormonal haemostatic profiles were also performed in the patients diagnosed as vWD. All patients had normal APTT. Based on von Willebrand factor work-up, vWD was diagnosed in four patients (13.3%). Three of them were Type 1 and the other one was Type 2M. Investigation for vWD is essential in patients with menorrhagia and thus the laboratories performing vWD testing should provide a complete panel of diagnostic work-up in order to reduce the interpretation error. Screening for vWD should be performed before hormonal treatment as haemostatic profile post treatment could mask the diagnosis.
Study site: Gynaecology clinic, Hospital of Universiti Sains Malaysia (HUSM), Kelantan, Malaysia

Matched MeSH terms: Adolescent

Kinetic asymmetries during running in male youth

Rumpf MC, Cronin JB, Mohamad IN, Mohamad S, Oliver JL, Hughes MG

Phys Ther Sport, 2014 Feb;15(1):53-7.

PMID: 23850007 DOI: 10.1016/j.ptsp.2013.03.001

A possible injury risk factor is limb asymmetry, which may differ across maturation given the adult growth spurt. The aim of this study is to quantify the magnitude of asymmetry in a number of kinetic variables during a running task in male youth of different maturity status.

Matched MeSH terms: Adolescent

Factors associated with illegal motorcycle street racing and help-seeking intention

Wong LP

Behav Med, 2012;38(2):54-63.

PMID: 22676631 DOI: 10.1080/08964289.2012.661804

The study aimed to identify the factors associated with street racing among the illegal motorcycle racers in Malaysia also known as the Mat Rempit, and their help-seeking intention. A total of 2,022 Mat Rempit were surveyed. The findings support the notion that experience-seeking, prestige-seeking, excitement-seeking, self-satisfaction, underestimate risk, and social influence were factors influencing illegal motorcycle street racing. The overall intention to seek help was extremely low. The majority (77.9%) reported that they would solve the problem themselves and 75.5% thought that illegal street racing is not big deal and would go away in time. Participants with neither (OR 0.41; 95% CI 0.27-0.62) or at least one parent who is strict (OR 0.52; 95% 0.37-0.73) were less likely to have high help-seeking intention than those with both parents who are strict. Study indicates a need for family-centered intervention to curb illegal street racing.

Matched MeSH terms: Adolescent

Fulltext Globe avulsion secondary to maxillofacial trauma

Norazah AR, Akmal HZ, Hashima H, Vasantha T, Samsudin A

Med J Malaysia, 2011 Oct;66(4):359-60.

PMID: 22299558 MyJurnal

We report a case of globe avulsion secondary to maxillofacial trauma and propose potential mechanisms of injury. This case highlights the importance of wearing proper safety attire, especially during motorcycling.

Matched MeSH terms: Adolescent

Fulltext Kleine Levin syndrome in Malaysia: first typical case

Bahari R, Ahmad SH

BMJ Case Rep, 2012;2012.

PMID: 22605587 DOI: 10.1136/bcr.08.2011.4679

A 13-year-old boy presented with a 2 weeks history of tearfulness, childish behaviour, separation anxiety, hypersomnia, hyperphagia and sexual disinhibition following a brief episode of fever. He had been experiencing the episodes since he was seven. The episodes lasted from a few days to 3 weeks and would normally occur once in a year. Most of the time it started with fever and resolved spontaneously. In the past he described auditory hallucination but not this time. Examination revealed a slightly overweight adolescent male appearing appropriate to his age. During the session he was restless, sleepy and burst into tears frequently. He constantly asked his mother when he could go home to sleep. He was very childish and clung to his mother. He was given a trial of risperidone 1 mg to be taken once a day for 3 days. On follow-up he had completely recovered.

Matched MeSH terms: Adolescent

Fulltext Chronic rectal bleeding in Proteus syndrome

Siow SL, Sim NK

Med J Malaysia, 2010 Dec;65(4):313-4.

PMID: 21901955

Proteus Syndrome is a rare congenital hamartomatous disorder that typically manifests itself in overgrowth, vascular malformation and disregulation of fatty tissue. The tissues affected are commonly the limbs but can be of any tissue. Vascular anomalies are common and appear at random sites on the body. Diagnosis is often difficult leading to wrong treatment. We describe a case of a 17-year-old girl with Proteus syndrome presented with symptomatic anaemia secondary to chronic rectal bleeding. Computed Tomography Angiogram of Abdomen and Pelvis confirmed the presence of rectal vascular malformations.

Matched MeSH terms: Adolescent

Quality of life of multiethnic adolescents living with a parent with cancer

Ainuddin HA, Loh SY, Low WY, Sapihis M, Roslani AC

Asian Pac J Cancer Prev, 2012;13(12):6289-94.

PMID: 23464447

BACKGROUND: Research evidence suggests a debilitating impact of the diagnosis of cancer on the quality of life of the afflicted individuals, their spouses and their families. However, relatively few studies have been carried out on the impact on the QOL of adolescents living with parents diagnosed with cancer. This paper presents a sub- analysis on the impact of parental cancer (colorectal, breast and lung) on adolescents.

MATERIALS AND METHODS: This is a cross-sectional study on adolescents aged 13-18 years old. Upon ethical clearance obtained from UMMC Medical Ethics Committee, patients with colorectal, breast or lung cancer and their adolescent children were recruited from the Clinical Oncology Unit of University of Malaya Medical Centre. Respondents who gave consent completed a demographic questionnaire and the Pediatric Quality of Life Inventory, via the post, email, home visit or meetings at the clinics.

RESULTS: 95 adolescents from 50 families responded, giving a response rate of 88 percent. The adolescent's mean age was 16 years (ranging between 13-18 years). Adolescents with parental cancer had the lowest mean score in emotional functioning (p<0.05). Male adolescents had significantly higher quality of life overall and in physical functioning compared to female adolescents. Adolescents with a father with cancer had better school functioning compared to adolescents whose mothers had cancer. Families with household income of RM 5000 and above have significantly better quality of life compared to families with lower household income.

CONCLUSIONS: Adolescent sons and daughters of parents with a cancer diagnosis show lowered QOL, particularly with reference to emotional functioning and school performance. Addressing the needs of this young group has been slow and warrants special attention. Revisiting the risk and resilience factors of adolescents might also inform tailored programs to address the needs of this neglected adolescent population.

Matched MeSH terms: Adolescent

Fulltext Two-stage surgery for a large cervical dumbbell tumour in neurofibromatosis 1: a case report

Mohd Ariff S, Joehaimey J, Ahmad Sabri O, Abdul Halim Y

Malays Orthop J, 2011 Nov;5(3):24-7.

PMID: 25279032 MyJurnal DOI: 10.5704/MOJ.1111.003

Spinal neurofibromas occur sporadically and typically occur in association with neurofibromatosis 1. Patients afflicted with neurofibromatosis 1 usually present with involvement of several nerve roots. This report describes the case of a 14- year-old child with a large intraspinal, but extradural tumour with paraspinal extension, dumbbell neurofibroma of the cervical region extending from the C2 to C4 vertebrae. The lesions were readily detected by MR imaging and were successfully resected in a two-stage surgery. The time interval between the first and second surgery was one month. We provide a brief review of the literature regarding various surgical approaches, emphasising the utility of anterior and posterior approaches.

Matched MeSH terms: Adolescent

Effect of pubertal developmental stages and lower limb kinetics during vertical jump task in Sepak Takraw sport

Leonard Joseph H, Roslizawati N, Safrusahar MY, Efri NM, Das S, Baharudin O, et al.

Clin Ter, 2009;160(5):403-7.

PMID: 19997687

Sepak Takraw is a sport which actively involves the lower limb. A cross sectional study was performed to investigate the lower limb kinetics (ground reaction force, flight time and contact time) involved during the vertical jumping and landing task between the early pubertal and late pubertal stages in National level Sepak Takraw athletes in Malaysia. Twenty athletes (8 pre pubertal and 12 late pubertal) with no previous history of any physical injuries were taken for the study. The kinetics data of the vertical jump task was calculated using a force platform 3-AMTI Biomechanics Force Platform. The Silicon ProCoach (Chart 5 software) was used to collect the ground reaction force signals, flight time and contact time. The results showed a non-significant decrease in peak ground reaction force in the post pubertal group as compared to the pre pubertal group (t(18)=0.659, p=0.518,CI(95)(-2.54, 4.86). Comparison of flight time between the two age groups showed a significant increase in the post pubertal group with mean and SD (0.7773 + or - 0.03) as compared to the pre pubertal group mean and SD (0.7296 + or - 0.05), which was statistically considered significant (p<0.05) (t(18)=-2.401, p<0.05,CI(95)(-0.089, -0.005). The findings from this study demonstrated that the flight time of the vertical jump task differed between the pre and post pubertal athletes with the post pubertal group having an improved ability in maintaining longer duration of flight phase.

Matched MeSH terms: Adolescent

Chan LL, Lin HP, Chong LA, Hany A, Ariffin AW

Med J Malaysia, 2009 Jun;64(2):124-9.

PMID: 20058571

Children who would benefit from a haematopoietic stem cell transplantation often lacked a compatible sibling donor. Unrelated cord blood transplantation was offered as an alternative donor source for patients with a variety of malignant and non-malignant diseases who had no further treatment options. Cord blood units were sourced from various international cord blood registries. The median nucleated and CD34+ cell doses were 8.7 x 10(7)/kg and 2.6 x 10(5)/kg respectively. In spite of adequate cell doses, a high rate of non-engraftment of 32% was observed. Acute graft-versus-host disease (GVHD) occurred in 14 out of the 15 patients who engrafted with 53% being grade III to IV GVHD. The five year disease free survival was 40.7% with infection and GVHD being the commonest causes of death. The five year disease free survival was 20.5% and 60.7% for malignant and non-malignant diseases respectively.

Matched MeSH terms: Adolescent

Fulltext Routine histological examination for nasal polyp specimens: is it necessary?

Irfan M, Shamim AK

Med J Malaysia, 2009 Mar;64(1):59-60.

PMID: 19852324 MyJurnal

Nasal polyp is one of the common causes of nasal obstruction. The diagnosis is usually made on clinical ground and rarely needs histological examination. However, when a candidate is selected for the surgical option of polyp removal, there is tendency to send all specimens for routine histological examination. The objective of this study was to assess the necessity of routinely performed histological examination in all nasal polyp specimens. A retrospective review of all nasal polyp histological reports was done from patients who underwent polypectomy or functional endoscopic sinus surgery in Universiti Sains Malaysia Hospital between January 2000 to July 2006. It consisted of 95 patients. Majority of the reports came back as inflammatory nasal polyp (93.6%) and other varieties of benign nasal mass (5.3%). However, one specimen was noted to be malignant (1.1%). In conclusion all nasal polyp specimens should be sent for histological examination in order to confirm the diagnosis.

Matched MeSH terms: Adolescent

Fulltext Surgical management of a massive facial hemangioma

Baharudin A, Samsudin AR, Halim AS, Shafie MA

Med J Malaysia, 2007 Aug;62(3):254-5.

PMID: 18246921 MyJurnal

Hemangiomas are the most common congenital lesions in man and occur predominantly in the head and neck region. Massive hemangioma especially near vital organs or structures pose a challenge to surgeons. With the availability of expertise in embolization of feeding vessel of the hemangioma and reconstructive techniques we were able to manage successfully a complicated case of massive facial hemangioma.

Matched MeSH terms: Adolescent

Spectrum of inherited metabolic disorders in Malaysia

Thong MK, Yunus ZM

Ann Acad Med Singap, 2008 Dec;37(12 Suppl):66-5.

PMID: 19904455

Issues pertaining to the diagnosis and management of inborn errors of metabolism (IEM) in Malaysia included low awareness of atypical and variable presentations in IEMs leading to delayed diagnosis or treatment, absence of reliable population data on IEMs and involvement of multiple siblings in the same family due to consanguinity. The importance of careful family history taking and genetic counselling are emphasised. Selected testing of ill infants and children for IEM yielded a positive 2% (264/13,500) results for IEMs in Malaysia. Out of the 264 patients, the spectrum of IEMs in Malaysia included organic acidurias (98), aminoacidopathies (78), urea cycle defects (54), neurotransmitter conditions (12) and lysosomal disorders, mainly mucopolysaccharidosis (14). Confirmatory studies of IEMs are an important aspect of management of IEMs. There is a need for more metabolic specialists and funding for diagnosis and treatment of IEMs in Malaysia. Long-term care issues and cost-effectiveness of IEM therapy, supportive and preventive aspects will need further studies in Malaysia.

Matched MeSH terms: Adolescent

Fulltext Insulinoma in Saudi Arabia: a twenty-year hospital study

Fouda MA, Malabu UH

Med J Malaysia, 2008 Jun;63(2):182-4.

PMID: 18942316

The study was designed to assess retrospectively clinical pattern of insulinoma at a national referral center in the Kingdom of Saudi Arabia. All cases of insulinoma recorded at King Khalid University Hospital Riyadh between January 1987 and December 2006 were reviewed. During the 20-year period five patients were seen comprising three females (ages 38, 40, and 70 years) and two males (17 and 34 years). The duration of symptoms prior to diagnosis ranged between one and eight years. The commonest mode of presentation before diagnosis was inability to observe Ramadan fasting. Other notable symptoms included dizziness and loss of consciousness. All the five patients proceeded to operation. At surgery all were found to be benign tumors. Post-operatively, three of the patients developed pseudocyst, which resolved upon undergoing second surgery. Though clinical presentation of insulinoma in Saudi subjects is similar to those reported in the literature, our study revealed prominent symptoms occurring during yearly ramadan religious fast could be a useful information in history taking. Further studies on a larger population are needed to further characterize our findings.

Matched MeSH terms: Adolescent

Fulltext A study of changes in the body composition components in the patients with pulmonary tuberculosis

Sharma G, Koley S, Sandhu JS, Kajal NC, Jorawar S

Med J Malaysia, 2008 Jun;63(2):118-21.

PMID: 18942296

The present study deals with the analysis of body composition components of 86 randomly selected patients with confirmed pulmonary tuberculosis aged 16- 70 years collected from the District Tuberculosis Centre and Hospital, Amritsar. An adequate number of controls were also taken for comparison. The findings of the present study showed highly significant differences (p < or = 0.001) in all the twelve kinanthropometric variables except height. When the data was further analyzed between sputum negative and sputum positive patients with pulmonary tuberculosis, highly significant differences (p < or = 0.001) were found only in total body fat and statistically significant differences (p < or = 0.05) were observed in weight, chest circumference in normal position, abdominal circumference, right calf and buttock circumferences. It may be concluded that TB patients were more malnourished than normal people. Thus, special nutritional care should be taken to the TB patients to give them a better quality of life.

Matched MeSH terms: Adolescent

Growing wealth and growing pains: child and adolescent psychiatry in Hong Kong, Malaysia and Singapore

Tan S, Fung D, Hung SF, Rey J

Australas Psychiatry, 2008 Jun;16(3):204-9.

PMID: 18568628 DOI: 10.1080/10398560701874283

Several Asian regions have undergone a dramatic transformation, some becoming very affluent. This paper aims to ascertain how countries that are becoming wealthy have dealt with child and adolescent mental health issues.

Matched MeSH terms: Adolescent; Adolescent Psychiatry/manpower; Adolescent Psychiatry/organization & administration*

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