MyMedR

Fulltext The first annual report of the National Eye Database 2007

Citation: The first annual report of the National Eye Database 2007. Goh PP, Hussein E, Mustari Z, Ismail M, editors. Kuala Lumpur: Clinical Research Centre; 2008

Matched MeSH terms: Eye Diseases

Abstracts of the 20th Asia Pacific Academy of Ophthalmology Congress, Kuala Lumpur, Malaysia, 27-31 March 2005

Am J Ophthalmol, 2005 Apr;139(4 Suppl):S1-71.

PMID: 16729358

Matched MeSH terms: Eye Diseases*

Medicine in Malaysia: ophthalmology

Selvarajah S

Med J Malaysia, 1995 May;50 Suppl A:S79-85.

PMID: 10968023

Matched MeSH terms: Eye Diseases/epidemiology

Investigation of ophthalmological conditions in Kelantan

McPherson HJ

Med J Malaya, 1965 Dec;20(2):126-31.

PMID: 4221973

Matched MeSH terms: Eye Diseases*

Revisiting the role of erythropoietin for treatment of ocular disorders

Shirley Ding SL, Leow SN, Munisvaradass R, Koh EH, Bastion ML, Then KY, et al.

Eye (Lond), 2016 Oct;30(10):1293-1309.

PMID: 27285322 DOI: 10.1038/eye.2016.94

Erythropoietin (EPO) is a glycoprotein hormone conventionally thought to be responsible only in producing red blood cells in our body. However, with the discovery of the presence of EPO and EPO receptors in the retinal layers, the EPO seems to have physiological roles in the eye. In this review, we revisit the role of EPO in the eye. We look into the biological role of EPO in the development of the eye and the physiologic roles that it has. Apart from that, we seek to understand the mechanisms and pathways of EPO that contributes to the therapeutic and pathological conditions of the various ocular disorders such as diabetic retinopathy, retinopathy of prematurity, glaucoma, age-related macular degeneration, optic neuritis, and retinal detachment. With these understandings, we discuss the clinical applications of EPO for treatment of ocular disorders, modes of administration, EPO formulations, current clinical trials, and its future directions.

Matched MeSH terms: Eye Diseases/drug therapy*; Eye Diseases/etiology; Eye Diseases/physiopathology; Eye Diseases/prevention & control

[Report of an ophthalmologic medical mission in Malaysia and Cambodia (January-February 1969)]

Guillaumat L

Bull Soc Ophtalmol Fr, 1969 May-Jun;69(5-6):554-9.

PMID: 5399666

Matched MeSH terms: Eye Diseases*

Intraocular parasitism

Rose L

Med J Malaya, 1965 Sep;20(1):65-7.

PMID: 4221425

Matched MeSH terms: Eye Diseases/complications*

The diabetic: his ocular complications and his visual prognosis

SINGH P

Med J Malaya, 1955 Sep;10(1):83-6.

PMID: 13287497

Matched MeSH terms: Eye Diseases*

Vitreous Humor: Composition, Characteristics and Implication on Intravitreal Drug Delivery

Mishra D, Gade S, Glover K, Sheshala R, Singh TRR

Curr Eye Res, 2023 Feb;48(2):208-218.

PMID: 36036478 DOI: 10.1080/02713683.2022.2119254

Purpose: Intravitreal administration of drug molecules is one of the most common routes for treating posterior segment eye diseases. However, the properties of vitreous humour changes with the time. A number of ocular complications such as liquefaction of the vitreous humour, solidification of the vitreous humour in the central vitreous cavity and detachment of the limiting membrane due to the shrinking of vitreous humour are some of the factors that can drastically affect the efficacy of therapeutics delivered via intravitreal route. Although significant research has been conducted for studying the properties of vitreous humour and its changes during the ageing process, there have been limited work to understand the effect of these changes on therapeutic efficacy of intravitreal drug delivery systems. Therefore, in this review we discussed both the coomposition and characteristics of the vitreous humour, and their subsequent influence on intravitreal drug delivery.Methods: Articles were searched on Scopus, PubMed and Web of Science up to March 2022.Results: In this review, we discussed the biological composition and biomechanical properties of vitreous humour, methods to study the properties of vitreous humour and the changes in these properties and their relevance in ocular drug delivery field, with the aim to provide a useful insight into these aspects which can aid the process of development of novel intravitreal drug delivery systems.Conclusions: The composition and characteristics of the vitreous humour, and how these change during natural aging processes, directly influence intravitreal drug delivery. This review therefore highlights the importance of understanding the properties of the vitreous and identifies the need to achieve greater understanding of how changing properties of the vitreous affect the therapeutic efficacy of drugs administered for the treatment of posterior eye diseases.

Matched MeSH terms: Eye Diseases*

Fulltext Parents' knowledge and practices of child eye health care: A scoping review

Ghani NDH, Mohamad Fadzil N, Mohammed Z, Abd Rahman MH, Che Din N

PLoS One, 2024;19(11):e0313220.

PMID: 39541317 DOI: 10.1371/journal.pone.0313220

BACKGROUND: Treating children's eyes is not just a privilege for a child, it is an essential requirement for their visual health. Parents, as caregivers, have a paramount responsibility to make decisions regarding their children's eye health. Thus, this review aims to identify and summarise published information about parents' knowledge and practices on children's eye health care.

METHODS: Relevant articles searches were performed through a systematic search of databases (EBSCOhost, PubMed, and Scopus) using the keywords 'knowledge', 'practice', 'parent', 'eye', 'problem', and 'children'. This review was conducted and reported in line with the PRISMA-ScR. The methodological quality of the listed studies was assessed using A Modified McMaster Critical Review form based on the total score.

RESULT: From a total of 235 studies retrieved through literature review and pearling, 219 remained after removing duplicates. After screening titles and abstracts, 204 irrelevant studies were excluded, leaving 15. After a detailed full-text review, four studies were excluded due to not meeting inclusion criteria. Thus, this review includes the remaining 11 studies. All eleven studies (n = 11) show that parents's knowledge and practices vary. Some parents display good knowledge regarding children's eye health care, for example, understanding the importance of wearing spectacles, the significance of children having normal vision, and where to seek eye examinations. Five studies (n = 5) showed that parents have good practices such as consulting doctors and seeking eye examinations and treatment at the hospital. Six studies (n = 6) showed that parents have misconceptions regarding knowledge, practices, and treatment of children's eye health.

CONCLUSION: This scoping review found that parents' knowledge and practices regarding children's eye health are poor. Parents' perceptions and practices about the cause and treatment of eye problems were tainted with misconceptions. Therefore, implementing structured programs to enhance awareness and promote the adoption of healthy practices for children's eye health is required.

Matched MeSH terms: Eye Diseases/therapy

Fulltext Giant cell arteritis with panocular involvement in an Indian male

Fathilah J, Jamaliah R

Med J Malaysia, 2003 Mar;58(1):111-4.

PMID: 14556335

A case of giant cell arteritis with systemic and panocular involvement is reported here. This elderly Indian male presented with symptoms of unilateral temporal headache and intermittent jaw claudication for a month followed by diplopia and blurring of vision and later loss of vision in the right eye. The right eye showed some limitation of ocular movements, presence of relative afferent pupil defect, anterior segment ischaemic changes and anterior ischaemic optic neuropathy. Visual evoked potential showed an absent P1 wave while the left eye with normal 6/6 vision sowed a prolonged P1 wave. Fundus fluoresceine angiography showed delay in choroidal perfusion. His erythrocyte sedimentation rate (ESR) was 120 mm/hr and he was started on oral prednisolone. Superficial temporal artery biopsy obtained one week after starting steroids was positive for giant cell arteritis. Steroids led to the resolution of optic disc swelling, disappearance of anterior segment signs, full recovery of right ocular movements and no further deterioration of the fellow eye. On steroids, he developed insomnia and progressive myopathy which resolved and is now symptom free at lower doses of steroids.

Matched MeSH terms: Eye Diseases/diagnosis*; Eye Diseases/etiology*; Eye Diseases/therapy

EBM Commentary. Is antibiotic eye drops essential for conjunctivitis?

Loh KY, Tee CT

Family Physician, 2005;13:18-18.

Matched MeSH terms: Eye Diseases

Eye injuries

Chandran S

Family Practitioner, 1976;2:7-9.

Matched MeSH terms: Eye Diseases

Treatment viability of stem cells in ophthalmology

Jeganathan VS, Palanisamy M

Curr Opin Ophthalmol, 2010 May;21(3):213-7.

PMID: 20393292 DOI: 10.1097/ICU.0b013e32833867ad

Adult ocular stem cells have the potential to restore vision in patients previously deemed incurable. This review summarizes strides in stem cell research and stumbling blocks that must be overcome to enable treatment viability in ophthalmology.

Matched MeSH terms: Eye Diseases/therapy*

Fulltext The dimensions of ocular morbidity amongst the nursing home geriatrics population

Normalina M, Zainal M

Med J Malaysia, 1998 Sep;53(3):239-44.

PMID: 10968160

A cross-sectional prevalence study amongst a nursing home elderly population was carried out at Rumah Sri Kenangan, Seremban, Negeri Sembilan between June 1995 until June 1996. A total of 204 cases of 60 years and older were examined in order to determine the ocular morbidity amongst them. It was found that 47.5% had low vision and 19.1% were legally blind. Cataract was found to be the leading cause of low vision and blindness occurring in 81.4% and 74.3% respectively. Glaucoma occurred in 1% of those who had low vision and none due to macular degeneration or diabetic retinopathy. The magnitude of visual impairment and blindness in this nursing home is high but is preventable and avoidable.

Matched MeSH terms: Eye Diseases/epidemiology*

Causes of blindness in Singapore

Lim KH

Med J Malaysia, 1975 Jun;29(4):263-9.

PMID: 1196175

Matched MeSH terms: Eye Diseases/complications

Fulltext Curcumin Metabolite Tetrahydrocurcumin in the Treatment of Eye Diseases

Kao YW, Hsu SK, Chen JY, Lin IL, Chen KJ, Lee PY, et al.

Int J Mol Sci, 2020 Dec 28;22(1).

PMID: 33379248 DOI: 10.3390/ijms22010212

Curcumin is one of the most valuable natural products due to its pharmacological activities. However, the low bioavailability of curcumin has long been a problem for its medicinal use. Large studies have been conducted to improve the use of curcumin; among these studies, curcumin metabolites have become a relatively new research focus over the past few years. Additionally, accumulating evidence suggests that curcumin or curcuminoid metabolites have similar or better biological activity than the precursor of curcumin. Recent studies focus on the protective role of plasma tetrahydrocurcumin (THC), a main metabolite of curcumin, against tumors and chronic inflammatory diseases. Nevertheless, studies of THC in eye diseases have not yet been conducted. Since ophthalmic conditions play a crucial role in worldwide public health, the prevention and treatment of ophthalmic diseases are of great concern. Therefore, the present study investigated the antioxidative, anti-inflammatory, antiangiogenic, and neuroprotective effects of THC on four major ocular diseases: age-related cataracts, glaucoma, age-related macular degeneration (AMD), and diabetic retinopathy (DR). While this study aimed to show curcumin as a promising potential solution for eye conditions and discusses the involved mechanistic pathways, further work is required for the clinical application of curcumin.

Matched MeSH terms: Eye Diseases/drug therapy*

Complications in cataract surgery

Singh K

Med J Malaysia, 1976 Sep;31(1):38-41.

PMID: 1088175

Matched MeSH terms: Eye Diseases/etiology

Preventive ophthalmology

Singh A

Med J Malaysia, 1977 Sep;32(1):45-7.

PMID: 609343

Matched MeSH terms: Eye Diseases/prevention & control*

Fulltext Orbital compartment syndrome in idiopathic orbital inflammatory disease: A case report

Tiong KI, Aziz S, Hazlita I

Med J Malaysia, 2015 Oct;70(5):316-7.

PMID: 26556124 MyJurnal

Orbital compartment syndrome (OCS) is a visual threatening ocular emergency. We report a 50-year-old male with acute presentation of OCS, a rare manifestation of idiopathic orbital inflammatory disease. At presentation, high intraocular pressure was reduced by prompt lateral canthotomy and cantholysis. The disease responded to systemic steroids and treatment resulted in good visual outcome. Detail evaluation and early detection and treatment are mandatory to prevent permanent vision loss.
Keywords: Sarawak General Hospital

Matched MeSH terms: Eye Diseases

Displaying publications 21 - 40 of 88 in total