Displaying publications 41 - 60 of 148 in total

Abstract:
Sort:
  1. Fulltext Melioidosis: a potentially life threatening infection
    How SH, Liam CK
    Med J Malaysia, 2006 Aug;61(3):386-94: quiz 395.
    PMID: 17240600
    Melioidosis is caused by the gram-negative bacillus, Burkholderia pseudomallei. It is endemic in tropical Australia and in Southeast Asian countries. The overall mortality from this infection remains extremely high despite recent advancement in its treatment. This review discuss about clinical manifestations, diagnosis and management of melioidosis.
  2. Gemcitabine and carboplatin in the treatment of locally advanced and metastatic non-small cell lung cancer
    Leow CH, Liam CK
    Respirology, 2005 Nov;10(5):629-35.
    PMID: 16268917
    The aim of the study was to evaluate the response, survival advantage and toxicity profile of gemcitabine-carboplatin combination cytotoxic chemotherapy in patients with locally advanced and metastatic non-small cell lung cancer (NSCLC).
  3. Mucinous carcinoma (colloid carcinoma) of the lung diagnosed by fine needle aspiration cytology: a case report
    Jayaram G, Yaccob R, Liam CK
    Malays J Pathol, 2003 Jun;25(1):63-8.
    PMID: 16196380
    Mucinous carcinoma of the lung, also known as colloid carcinoma, is an uncommon tumour that is rarely encountered in fine needle aspiration (FNA) cytological practice. A 64-year-old Chinese male presenting with blood stained sputum and hoarseness of voice was discovered to have a 3 cm sized mass in the left lung. Neither bronchial washings nor transthoracic FNA yielded positive results at this stage. Six months later the patient returned to the hospital with a larger tumour and mediastinal lymphadenopathy. Transbronchial lymph node FNA, reported as negative for malignancy showed normal, hyperplastic and mildly atypical bronchial epithelial cells as well as a few single cells and extracellular mucin. Transthoracic FNA of the lung lesion performed under computed tomographic guidance showed characteristic cytological features of this tumour, establishing the diagnosis.
  4. Fulltext Community acquired pneumonia--a Malaysian perspective
    Liam CK
    Med J Malaysia, 2005 Jun;60(2):249-65; quiz 266.
    PMID: 16114172
  5. The direct cost of treating bronchial asthma in a teaching hospital in Malaysia
    Chan PW, Hussain S, Ghani NH, Debruyne JA, Liam CK
    Southeast Asian J. Trop. Med. Public Health, 2002 Sep;33(3):600-3.
    PMID: 12693597
    A pilot study to evaluate the direct cost of treating 51 adults and 50 children with bronchial asthma was conducted. All aspects of the medical care provided over a 6-month period were considered. The mean treatment costs per month were US dollars 22.97 (adults) and US dollars 15.56 (children). The cost of maintenance therapy accounted for 55.5% and 73.4% of the total direct cost treatment for adults and children respectively. Only 27 (52.9%) adults and 17 (34.0%) children paid for their inhaled prophylactic drugs, amounting to 12.3% of the total maintenance therapy costs. Thirteen (25.4%) adults and 9 (18.0%) children were using alternative therapy at a monthly cost of US dollars 41.50 and US dollars 16.77 respectively. A substantial proportion of the direct cost of asthma treatment is heavily subsidized in Malaysia. Adequate attention to the allocation of the health budget, to ensure the optimal provision of health care, is warranted.
  6. Fulltext Current trends in the management of chronic obstructive pulmonary disease
    Liam CK
    Med J Malaysia, 2000 Jun;55(2):285-92; quiz 293.
    PMID: 19839165
  7. The causes of haemoptysis in malaysian patients aged over 60 and the diagnostic yield of different investigations
    Wong CM, Lim KH, Liam CK
    Respirology, 2003 Mar;8(1):65-8.
    PMID: 12856744
    OBJECTIVE: In southeast Asia, pulmonary tuberculosis (TB) is the most frequently presumed diagnosis for haemoptysis. This study was designed to assess the causes of haemoptysis, the diagnostic yield of causes in different diagnostic modalities and the distribution of older patients.

    METHODS: All patients presenting to the University of Malaya Medical Centre, Kuala Lumpur, Malaysia with haemoptysis were recruited prospectively and evaluated.

    RESULTS: One hundred and sixty patients were evaluated for haemoptysis; 71 (44.4%) were aged 60 years or more. Significantly more patients smoked in the older age group (P = 0.002). The main causes of haemoptysis in the older patients were bronchogenic carcinoma (49.3%), pneumonia (11.3%), bronchiectasis (8.6%), cryptogenic (5.6%) and active TB (4.2%). Significantly more older patients had carcinoma (P < 0.001), while the younger patients more often had TB (P < 0.001). Chest pain was significantly more common in the older patients (P = 0.025), particularly in patients with carcinoma. Bronchoscopy alone or combined with CT of the thorax was significantly more diagnostic in the older patient (P = 0.006).

    CONCLUSION: Bronchogenic carcinoma is the commonest cause of haemoptysis in patients aged 60 years and above. Presumptive anti-TB therapy should not be encouraged despite the regional high prevalence of TB.

  8. Metastatic lung cancer in pregnancy
    Wong CM, Lim KH, Liam CK
    Respirology, 2003 Mar;8(1):107-9.
    PMID: 12856752
    Pregnancy complicated by lung cancer has been rarely reported. The regional incidence of this complex situation is likely to increase in the future and optimal management needs to be established to better deal with this situation. We report two patients with metastatic lung cancer complicating pregnancy to highlight the evaluation and management difficulties associated with this problem and to contribute to the limited information in the literature.
  9. Massive pleural effusions in cryptococcal meningitis
    Wong CM, Lim KH, Liam CK
    Postgrad Med J, 1999 May;75(883):297-8.
    PMID: 10533638
    Cryptococcal infection uncommonly presents with pulmonary manifestations and even more rarely so as massive bilateral effusions. Pleural involvement is usually associated with underlying pulmonary parenchymal lesions and is unusual while on antifungal therapy. We report a patient with cryptococcal meningitis who, while on intravenous 5-flucytosine and amphotericin B, developed life-threatening bilateral massive pleural effusions with evidence of spontaneous resolution, consistent with prior hypothesis of antigenic stimulation as the cause of pleural involvement.
  10. Fulltext Assessment and management of chronic cough
    Wong CMM, Lim KH, Liam CK
    Med J Malaysia, 2002 Dec;57(4):515-23; quiz 524-5.
    PMID: 12733182
  11. Fulltext Risk of tuberculosis to healthcare workers
    Liam CK
    Med J Malaysia, 2001 Mar;56(1):107-11; quiz 112.
    PMID: 11503290
  12. Fulltext Is snoring a health risk?
    Liam CK
    Med J Malaysia, 1999 Mar;54(1):155-9; quiz 160.
    PMID: 10972023
  13. Common fears of patients undergoing bronchoscopy
    Poi PJ, Chuah SY, Srinivas P, Liam CK
    Eur Respir J, 1998 May;11(5):1147-9.
    PMID: 9648970
    In the world of medical literature, little has been reported about the fears of patients undergoing bronchoscopy. The aim of this study was to identify the common fears of patients undergoing fibreoptic bronchoscopy and to determine whether any factors might contribute to reducing these fears. One hundred and four consecutive patients undergoing bronchoscopy were interviewed. Sixty one patients expressed fear about the procedure, as follows: afraid of pain (33); afraid of breathing difficulties (11); afraid of oropharyngeal irritation (5); afraid of the bronchoscopy findings (2); afraid of sedation, cross-infection and nasal lignocaine spray, respectively (3); and unable to be specific (7). There was no difference between the "no fear" and "fearful" groups in ethnicity, source of referral, education, previous endoscopy, doctors' explanation and the patients' understanding of the procedure and its indication. "Fearful" patients were significantly younger (t=2.082, p=0.037) and female (chi2=4.180, p=0.038). Doctors were more likely to explain the indication for bronchoscopy than how it would be performed (chi2=6.403; p=0.011), and patients were more likely to understand why they needed a bronchoscopy than how it would be performed (chi2=21.505; p<0.001). Fear preceding bronchoscopy is independent of patients' demographic features except for age and gender. Doctors tend to explain "why" but not "how" the procedure is performed. Provision of detailed information about sensations that are likely to be experienced in bronchoscopy could be used to allay some of these common fears.
  14. Fulltext Clubbing of the fingers in patients with primary lung cancer
    Liam CK
    Med J Malaysia, 1997 Jun;52(2):186-7.
    PMID: 10968082
  15. Fulltext Septicaemic pulmonary melioidosis with cutaneous pustules
    Liam CK
    Med J Malaysia, 1993 Jun;48(2):248-9.
    PMID: 8350807
  16. Fulltext Cor pulmonale due to obstructive sleep apnoea
    Liam CK
    Med J Malaysia, 1993 Sep;48(3):347-50.
    PMID: 8183151
    A 47 year old man with a long history of chronic loud snoring and daytime sleepiness presented with hypercapnic respiratory failure and right ventricular failure. The diagnosis of obstructive sleep apnoea (OSA) leading to the 'obesity-hypoventilation syndrome', was supported by the findings of an overnight cardio-respiratory monitoring during sleep. His symptoms and arterial blood gases improved following treatment with nocturnal nasal continuous positive airway pressure (CPAP).
  17. Fulltext A portal recording system for the assessment of patients with sleep apnoea syndrome
    Liam CK
    Med J Malaysia, 1996 Mar;51(1):82-8.
    PMID: 10967984
    The gold standard for the diagnosis and evaluation of sleep apnoea is overnight polysomnography. However, full polysomnography is an expensive and labour intensive procedure which requires the patient to sleep overnight in a hospital sleep laboratory. This paper describes the use of a commercial ambulatory microprocessor based system (Edentrace II) for the evaluation of fifteen patients aged 24 to 68 years with clinical features suggestive of sleep apnoea syndrome. With this portable recording system, sleep studies can be carried out unattended in a hospital ward and computer-assisted scoring of respiratory events can be performed.
    Study site: Chest clinic, wards, University Malaya Medical Centre (UMMC), Kuala Lumpur, Malaysia
  18. Development of Aeromonas hydrophila bacteremia in a patient recovering from cholera
    Riley PA, Parasakthi N, Liam CK
    Clin Infect Dis, 1996 May;22(5):867-8.
    PMID: 8722957
  19. Fulltext Intrapulmonary bronchogenic cyst presenting with haemoptysis
    Liam CK
    Med J Malaysia, 1994 Dec;49(4):404-5.
    PMID: 7674976
    A 36-year-old man presented with haemoptysis and his admission chest radiograph showed a large thin walled cystic lesion with an air-fluid level in the left lower lobe. The pathological diagnosis of the lesion, which was removed by a left lower lobe resection, was an intrapulmonary bronchogenic cyst.
  20. Fulltext Significant morbidity associated with asthma: a need for increased doctor and patient education
    Liam CK
    Med J Malaysia, 2003 Oct;58(4):471-4.
    PMID: 15190620
Related Terms
Filters
Contact Us

Please provide feedback to Administrator (afdal@afpm.org.my)

External Links