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Fulltext Investigating the relationship between post- traumatic stress disorder (PTSD) symptoms and emotional intelligence among adolescent refugees from the Middle East

Siti Raudzah Ghazali

ASEAN Journal of Psychiatry, 2014;15(2):220-224.
MyJurnal

Objective: The objective of this study was to establish the relationship between symptoms of PTSD and various scores of emotional intelligence scales. This study employed a cross-sectional research design. Participants were recruited from the local community health centre in Dearborn, Michigan, USA. The Child Posttraumatic Stress Reaction Index (CPTS-RI) measured the presence of PTSD symptoms and the Adolescents Multifactor Emotional Intelligence Scale (AMEIS) measured emotional intelligence. Results: The findings suggest an inverse relationship between PTSD severity and emotional intelligence. The PTSD score was negatively correlated with all AMEIS subscales. Two significant negative correlations were found in the tasks of using emotion and understanding emotion. Conclusion: Findings suggest that individuals with severe PTSD symptoms appear to lack the abilities to understand and use emotions. These findings might be useful in identifying factors that may contribute to decreasing the severity of PTSD symptoms of these children. Implications of the findings were discussed, and recommendations for future research are presented. ASEAN Journal of Psychiatry, Vol. 15 (2), July - December 2014: 220-224.

Matched MeSH terms: Stress Disorders, Post-Traumatic
Fulltext Translation and validation of the Malay post traumatic stress disorder checklist for civilians

Rafidah Bahari, Muhammad N Mohamad Alwi, Muhammad R Ahmad, Ismail Mohd Saiboon

ASEAN Journal of Psychiatry, 2015;16(2):203-211.
MyJurnal

There are a number of validated questionnaires available for the screening of Post-Traumatic Stress Disorder (PTSD), and the PTSD Checklist for Civilians is one of them. However, none was translated into the Malay Language and validated for use in the Malaysian population. The aim of this study is to translate and validate the Malay PTSD Checklist for Civilians (MPCL-C). Methods: The PCL-C was translated into the Malay Language and back-translated. The reliability and validity of the MPCL-C were then determined by administering them to those who presented at the emergency department for motor vehicle accident at least one month before. Results: The MPCL-C has good face and content validity. In terms of reliability, it is also good, with Chronbach’s alpha values of 0.90, 0.77, 0.75 and 0.74 for the full scale, re-experiencing, avoidance and arousal domains respectively. Conclusions: The MPCL-C is a valid and reliable instrument to screen for PTSD in motor vehicle accident victims for the studied population.

Matched MeSH terms: Stress Disorders, Post-Traumatic
Fulltext Post-traumatic stress disorder and its associated factors among school-going children exposed to a tsunami disaster in Malaysia

Idris, I.B., Shamsudin K., Aniza, I, Khairani, O, Rahmah M.A.

Malaysian Journal of Public Health Medicine, 2015;15(3):112-121.
MyJurnal

Posttraumatic stress disorder (PTSD) is a psychiatric diagnosis made when someone including children who experiences traumatic stressor. Those who are exposed to a more severe trauma have highest level of PTSD. The aim of this study was to measure the prevalence of PTSD and its associated factors among 219 children who were affected by a form of natural disaster which is the tsunami waves in a rural area in Malaysia. A cross sectional study was carried out among children aged 10-12 years 6 months after the traumatic event. Child Posttraumatic Stress Disorder –Reaction Index (CPTSD-RI) was used as a screening instrument which was answered by the affected children through a self-administered questionnaire. Forty six percent of these children had PTSD symptoms; 31.1% of these children had mild, 11.4% had moderate, 3.7% had severe PTSD and none had very severe PTSD. Result also showed that 91.8% had re-experiencing symptoms, 28.3% had numbing/avoidance symptoms and 49.3% had hyperarousal symptoms. Children with low social support (Adj OR = 2.3 (95% CI: = 1.3- 4.2)), and children who experienced deaths among someone close to them (Adj OR = 3.7 (95% CI =1.2 - 11.5)) were more likely to have symptoms of PTSD. This showed that children are at higher risk of developing PTSD as early as 6 months after the event and thus early intervention should be offered to them. Future longitudinal study can be carried out among affected children to assess whether these PTSD symptoms persist over time.

Matched MeSH terms: Stress Disorders, Post-Traumatic
Fulltext Epigenetics, mental health and transgenerational epigenetic effects

Lake, H., Pridmore, S.

Malaysian Journal of Psychiatry, 2014;23(1):89-100.
MyJurnal

Objective: to review the field of epigenetics, and present basic and recent material that may be of interest to clinical psychiatrists. We include basic molecular mechanism, a consideration of findings related to mental disorders, evidence of sustained effects, and the evidence for and implications of transgenerational epigenetic modifications. Method: we examined all the available papers for the last five years identified by PubMed using the words ‘epigenetics’ and ‘epigenetics psychiatry’, and the available leading specialized textbooks. Results: we report on molecular mechanisms including DNA and histone modifications, and non-coding RNAs. While some modifications are short-lived, others are life-long. Depression, suicide, schizophrenia, PTSD, borderline personality disorder and drug addiction are among the conditions for which epigenetic involvement has been proposed. Transgenerational epigenetics enables the environmental experience of one generation to be non-genetically inherited by subsequent generations. This has been molecularly demonstrated in laboratory animals and epidemically suggested in humans. Conclusions: epigenetics provides a new way of understanding human behavior and points to potential therapies for mental disorders. Should it transpire that transgenerational epigenetic modifications apply with force in humans as they do to laboratory animals, this will emphasize the need for cultural shift, safe societies with ample opportunities.

Matched MeSH terms: Stress Disorders, Post-Traumatic
Fulltext Dental health status and oral health behavior among university students from five ASEAN countries

Peltzer K, Pengpid S

Nagoya J Med Sci, 2017 02;79(2):123-133.
PMID: 28626248 DOI: 10.18999/nagjms.79.2.123

The aim of this study was to investigate dental health status and oral health behavior and associated factors among university students in five ASEAN countries (Indonesia, Malaysia, Myanmar, Thailand and Vietnam). Using anonymous questionnaires, data were collected from 3,344 undergraduate university students (mean age 20.5, SD=1.6; 58.3% female) from five ASEAN countries. Results indicate that 27.7% of students reported to have sometimes, most of the time or always having tooth ache in the past 12 months, 39.4% reported to have one or more cavities, 20.3% did not brush their teeth twice or more times a day, and 30.9% had never been to a dentist (or did not know it). In multivariate logistic regression analysis, older age, living in a lower middle income country, consumption of chocolate or candy, having made a dental care visit, and poor mental health was associated with tooth ache in the past 12 months. Being male, being 20 to 21 years old, coming from a wealthier family background, living in a lower middle income country, frequent consumption of soft drinks, not having consulted with a dentist in the past 12 months and weak beliefs in the benefits of tooth brushing were associated with inadequate tooth brushing frequency (

Matched MeSH terms: Stress Disorders, Post-Traumatic/epidemiology
Fulltext Enhanced Contextual Fear Memory and Elevated Astroglial Glutamate Synthase Activity in Hippocampal CA1 BChE shRNA Knockdown Mice

Chen S, Lin Z, Tan KL, Chen R, Su W, Zhao H, et al.

Front Psychiatry, 2020;11:564843.
PMID: 33061920 DOI: 10.3389/fpsyt.2020.564843

Butyrylcholinesterase (BChE) efficiently hydrolyzes acetylcholine (ACh) at high concentrations when acetylcholinesterase (AChE) is substrate-inhibited. Recent studies have shown that BChE also has a function that is independent of ACh, but it has not been fully explored. Low BChE expression is accompanied with higher stress-induced aggression and ghrelin levels in stress models, and BChE knockout mice exhibit cognitive and memory impairments. However, the role of BChE in posttraumatic stress disorder (PTSD) remains unclear. In the present study, we investigated the role of BChE in contextual fear memory and its regulatory effect on the expression of factors related to the glutamate (Glu)-glutamine (Gln) cycle via knockdown studies. We used AAVs and lentiviruses to knockdown BChE expression in the mouse hippocampal CA1 region and C8D1A astrocytes. Our behavioral data from those mice injected with AAV-shBChE in the hippocampal CA1 region showed strengthened fear memory and increased dendritic spine density. Elevated Glu levels and glutamine synthetase (GS) enzyme activity were detected in contextual fear conditioned-BChE knockdown animals and astrocytes. We observed that an AAV-shBChE induced lowering of BChE expression in the hippocampus CA1 region enhanced contextual fear memory expression and promoted the astrocytic Glu-Gln cycle but did not elevate ACh-hydrolyzing activity. This study provides new insight into the regulatory role of BChE in cognition and suggests potential target for stress-related psychiatric disorder such as PTSD where patients experience fear after exposure to severe life-threatening traumatic events.

Matched MeSH terms: Stress Disorders, Post-Traumatic
Fulltext High carbonated soft drink consumption is associated with externalizing but not internalizing behaviours among university students in five ASEAN states

Pengpid S, Peltzer K

Psychol Res Behav Manag, 2019;12:585-592.
PMID: 31534377 DOI: 10.2147/PRBM.S209611

Background: The investigation aimed to estimate the association between carbonated soft drink consumption frequency and externalizing and internalizing behaviour among university students in five ASEAN counties.
Methods: A cross-sectional survey included 3353 university students from Indonesia, Malaysia, Myanmar, Thailand and Vietnam, median age 20 years (interquartile range 3 years).
Results: In all five ASEAN countries, the study found a prevalence no soft drink consumption in the past 30 days of 20.3%, less than one time a day 44.7%, once a day 25.4% and two or more times a day 9.6%. In the adjusted logistic regression analysis, higher frequency of soft drink consumption (one and/or two or more times a day) was associated with externalizing behaviour (in physical fight, injury, current tobacco use, problem drinking, drug use, pathological internet use and gambling behaviour), and higher frequency of soft drink consumption (two or more times a day) was associated with depression in females, but no association was found for the general student population in relation to internalizing behaviour (depression, posttraumatic stress disorder, suicidal ideation, suicide plan, suicide attempt and sleeping problem).
Conclusions: Findings suggest that carbonated soft drink consumption is associated with a number of externalizing but not internalizing health risk behaviours.

Matched MeSH terms: Stress Disorders, Post-Traumatic
Fulltext The Malay posttraumatic stress disorder checklist for DSM-5 (MPCLC-5) as screening tool for ptsd: determination of cut-off point against clinician administered PTSD scale for DSM-5 (CAPS-5)

Muhammad Najib Mohamad Alwi, Rafidah Bahari

Malaysian Journal of Medicine and Health Sciences, 2020;16(107):13-17.
MyJurnal

Introduction: Posttraumatic stress disorder (PTSD) is a mental health condition which develops following exposure to life-threatening events. This cross-sectional study was conducted among adult patients from all walks of life who had injuries related to motor vehicle accidents to determine the cut-off point of the Malay Posttraumatic Stress Disorder Checklist For DSM-5 (MPCLC-5) for its use as a screening tool for PTSD in the Malaysian population. Methods: Using convenient sampling method, 204 subjects who fulfilled the inclusion criteria were recruited and they were given the 17 item self-rated MPCLC-5 to fill up. Subsequently, trained personnel administered the gold standard Clinician Administered PTSD Scale for DSM 5 (CAPS-5). ROC curve analysis was done to determine appropriate cut-off point for the MPCLC-5. Results: Cut off point of 42/43 would yield the most preferable sensitivity and specificity for MPCLC-5 when compared to CAPS-5 (Sensitivity: 67.56% (95%CI 55.68% to 78.00%); Specificity : 80% (95% CI 72.08% to 86.50%) ). Conclusion: The easy to administer MPCLC-5 is suitable for screening of PTSD among local patients with a proposed cut off point of 42/43.

Matched MeSH terms: Stress Disorders, Post-Traumatic
Fulltext The prevalence and factors influencing posttraumatic stress disorders (PTSD) among helpseeking women experiencing domestic violence in Malaysia

Normah Che Din, Soo, Siew Bee, Subramaniam, Ponnusamy, Ng, Lai Oon

ASEAN Journal of Psychiatry, 2010;11(2):158-170.
MyJurnal

Objective: The aim of the study is to examine the prevalence and factors influencing PTSD among a sample of help-seeking women experiencing domestic violence. Methods: This was a cross-sectional survey study of 40 women in two shelters in Malaysia from 2007 to 2008. Measures include the Detailed Assessment of Posttraumatic Stress; the Measure of Wife Abuse; the Posttraumatic Cognitions Inventory; the Coping Scale for Adults; and the Provision of Social Relations. Results: Results showed that 60% of subjects
exhibited patterns of symptoms consistent with the diagnosis of PTSD. The most prominent posttraumatic symptoms reported were re-experience, avoidance, dissociative responses, and symptoms of increased arousal. Both negative appraisals about themselves and self blame for the abusive situations were positively associated with increased tendency to develop PTSD. The greater use of optimism coping style and the higher quality social
support appeared to lead to a significantly reduced tendency of developing PTSD. Negative appraisals about themselves were found to be the strongest positive predictor of PTSD [R² = 0.32, F(1,38)=17.67, p

Matched MeSH terms: Stress Disorders, Post-Traumatic
Fulltext Incidence and demographical characteristics of patients with post-traumatic stress disorder due to motor vehicle accidents

Bahari R, Mohamad Alwi MN, Ahmad MR, Mohd Saiboon I

Malays Fam Physician, 2017;12(3):2-7.
PMID: 29527273 MyJurnal

Introduction: Motor vehicle accidents (MVAs) are daily occurrences in Malaysia but the extent to which victims are psychologically affected is not well known. The objective of this study is to determine the incidence and demographic characteristics of patients with post-traumatic stress disorder (PTSD) due to MVAs at a university hospital in Malaysia.
Methods: Patients presenting to the emergency department from August to October 2014 due to MVA-related injuries were recruited. After a period of at least one month, they were followed-up and screened using the validated Malay Post Traumatic Stress Disorder Checklist Civilian version. A score of 30 was chosen as the cut-off point for PTSD.
Results: In total, 112 patients presented to the emergency department following MVAs during the study period. Of these, 60.7% agreed for the follow-up. Among the respondents, the mean age was 26 years, 91.2% were males, 66.2% were married, 85.3% were Malays and 88.3% were Muslims. The calculated incidence of PTSD was 7.4%. There was no significant difference noted between the PTSD and non-PTSD groups.
Conclusion: A considerable number of MVA victims in Malaysia may develop PTSD after the accident. Further research is needed to explore the factors that contribute or protect to develop the condition.

Matched MeSH terms: Stress Disorders, Post-Traumatic

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