Displaying publications 61 - 80 of 284 in total

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  1. Wilson RG
    J R Nav Med Serv, 1973;59(1):30-4.
    PMID: 4147205
    Matched MeSH terms: Great Britain
  2. Griffiths DA
    Can J Microbiol, 1966 Feb;12(1):149-63.
    PMID: 5923132
    Matched MeSH terms: Great Britain
  3. Bakri NN, Tsakos G, Masood M
    Br Dent J, 2018 07 27;225(2):153-158.
    PMID: 30050198 DOI: 10.1038/sj.bdj.2018.529
    Objective: The primary objective of this study was to examine the association between smoking and oral health-related quality of life (OHRQoL) among dentate people aged 16 years and above in England.
    Methods: Cross-sectional study, based on the Adult Dental Health Survey (ADHS) 2009. ADHS 2009 involved data collection from 11,380 face-to-face interviews and 6,469 dental examinations from England, Wales and Northern Ireland. This study focuses on the dentate sample from England, consisting of 5,622 individuals who underwent dental examination. OHRQoL was measured by two indices; Oral Health Impact Profile-14 (OHIP-14) and Oral Impacts on Daily Performance (OIDP). Unadjusted and adjusted zero-inflated regression models were used. Adjustment was sequentially done for socio-demographics, clinical oral conditions and self-reported general health.
    Results: Prevalence of those who had never smoked, past smokers and current smokers were 45.6%, 35.3% and 19.2% respectively. Current smokers had considerably higher mean OHIP-14 and OIDP scores than non-smokers. There was a statistically significant association between smoking and OHRQoL (both OHIP-14 and OIDP) even in the fully adjusted models. Current smokers were more likely to report worse OHRQoL compared to those who had never smoked in both OHIP-14 and OIDP score. There was no statistically significant difference between past smokers with those who had never smoked in reporting OHIP-14 and OIDP. Among those reporting OHRQoL, there was a stepwise gradient risk of reporting no oral impact, where the probability was higher among those who had never smoked, followed by past smokers and current smokers both in OHIP-14 and OIDP.
    Conclusion: Smoking was independently associated with worse OHRQoL, even after adjusting for a range of socio-demographic factors, clinical oral conditions and self-reported general health.
    Matched MeSH terms: Great Britain
  4. Yu H, Zahidi I, Liang D
    Environ Res, 2023 May 15;225:115613.
    PMID: 36870554 DOI: 10.1016/j.envres.2023.115613
    Dartford, a town in England, heavily relied on industrial production, particularly mining, which caused significant environmental pollution and geological damage. However, in recent years, several companies have collaborated under the guidance of the local authorities to reclaim the abandoned mine land in Dartford and develop it into homes, known as the Ebbsfleet Garden City project. This project is highly innovative as it not only focuses on environmental management but also provides potential economic benefits, employment opportunities, builds a sustainable and interconnected community, fosters urban development and brings people closer together. This paper presents a fascinating case that employs satellite imagery, statistical data, and Fractional Vegetation Cover (FVC) calculations to analyse the re-vegetation progress of Dartford and the development of the Ebbsfleet Garden City project. The findings indicate that Dartford has successfully reclaimed and re-vegetated the mine land, maintaining a high vegetation cover level while the Ebbsfleet Garden City project has advanced. This suggests that Dartford is committed to environmental management and sustainable development while pursuing construction projects.
    Matched MeSH terms: Great Britain
  5. Longhurst P, Swami V
    J Affect Disord, 2023 Aug 01;334:121-128.
    PMID: 37156268 DOI: 10.1016/j.jad.2023.04.142
    BACKGROUND: Research has increasingly examined the ways in which internal bodily experiences influence body image, including the relationship between alexithymia - the reduced ability to identify and describe one's own emotional feelings and bodily sensations - and negative body image. However, relationships between facets of alexithymia and positive body image remain unexplored.

    METHODS: To bridge this gap in the literature, we assessed relationships between facets of alexithymia and multiple, core indices of positive body image in an online sample of adults from the United Kingdom. A total of 395 participants (226 women, 169 men) aged 18 to 84 years completed measures of alexithymia, body appreciation, functionality appreciation, body image flexibility, body acceptance by others, and positive rational acceptance.

    RESULTS: Once the effects of age had been accounted for, alexithymia was significantly and negatively associated with all five body image constructs in hierarchical multiple regressions. In the final models, the alexithymia facet of Difficulties Identifying Feeling emerged as a significant and negative predictor of all indices of positive body image.

    LIMITATIONS: The use of cross-sectional data limits the causal conclusions that can be drawn.

    CONCLUSIONS: These findings extend previous work by demonstrating the unique relationship between alexithymia and positive body image, providing important implications for body image research and practice.

    Matched MeSH terms: Great Britain
  6. Osterrieder A, Cuman G, Pan-Ngum W, Cheah PK, Cheah PK, Peerawaranun P, et al.
    BMJ Open, 2021 Jul 20;11(7):e046863.
    PMID: 34285007 DOI: 10.1136/bmjopen-2020-046863
    OBJECTIVES: To understand the impact of COVID-19 and public health measures on different social groups, we conducted a mixed-methods study in five countries ('SEBCOV-social, ethical and behavioural aspects of COVID-19'). Here, we report the results of the online survey.

    STUDY DESIGN AND STATISTICAL ANALYSIS: Overall, 5058 respondents from Thailand, Malaysia, the UK, Italy and Slovenia completed the self-administered survey between May and June 2020. Poststratification weighting was applied, and associations between categorical variables assessed. Frequency counts and percentages were used to summarise categorical data. Associations between categorical variables were assessed using Pearson's χ2 test. Data were analysed in Stata 15.0 RESULTS: Among the five countries, Thai respondents reported having been most, and Slovenian respondents least, affected economically. The following factors were associated with greater negative economic impacts: being 18-24 years or 65 years or older; lower education levels; larger households; having children under 18 in the household and and having flexible/no income. Regarding social impact, respondents expressed most concern about their social life, physical health, mental health and well-being.There were large differences between countries in terms of voluntary behavioural change, and in compliance and agreement with COVID-19 restrictions. Overall, self-reported compliance was higher among respondents who self-reported a high understanding of COVID-19. UK respondents felt able to cope the longest and Thai respondents the shortest with only going out for essential needs or work. Many respondents reported seeing news perceived to be fake, the proportion varying between countries, with education level and self-reported levels of understanding of COVID-19.

    CONCLUSIONS: Our data showed that COVID-19 and public health measures have uneven economic and social impacts on people from different countries and social groups. Understanding the factors associated with these impacts can help to inform future public health interventions and mitigate their negative consequences.

    TRIAL REGISTRATION NUMBER: TCTR20200401002.

    Matched MeSH terms: Great Britain
  7. Davenport C, Swami V
    Issues Ment Health Nurs, 2023 Dec;44(12):1188-1199.
    PMID: 37819864 DOI: 10.1080/01612840.2023.2262574
    Understandings of paternal postnatal depression (PND) in fathers from the United Kingdom (UK) have received limited attention, particularly in view of changing dynamics of contemporary parenthood. To rectify this, eight UK fathers with PND took part in one-to-one interviews, with Interpretative Phenomenological Analysis used to understand their lived experiences. Our findings demonstrate that UK fathers with PND experienced extremely distressing emotions, including anger and misery, after their babies are born. Their working practices were highly relevant to their fatherhood, with working considered a key responsibility and a source of stress, but also a "legitimate" escape from the home. Fathers' relationships with their partners were experienced as less intimate and conflicted. Fathers often hid their feelings to protect their partners, but also reported their partners as being aware of their challenging and difficult emotions. Healthcare providers should be professionally curious about fathers' mental health and consider the assistance of mothers in identifying cases of paternal PND.
    Matched MeSH terms: Great Britain
  8. Swami V, Voracek M, Todd J, Furnham A, Horne G, Tran US
    Body Image, 2024 Mar;48:101685.
    PMID: 38382233 DOI: 10.1016/j.bodyim.2024.101685
    Previous work has supported direct, positive associations between body appreciation and positive mental health, but has largely neglected to examine possible indirect mechanistic pathways. Here, we propose one relevant mediational pathway, wherein body appreciation is associated with positive mental health via positive self-beliefs (i.e., cognitions that lead individuals to view themselves, their lives, and/or their futures under a positive outlook). To test this hypothesis, we asked an online sample of 496 adults (249 women, 247 men) from the United Kingdom to complete measures of body appreciation, positive self-beliefs, and positive mental health. Participants also completed measures of self-efficacy and resilience, and provided their demographic information. Correlational analysis revealed significant, positive, and strong associations between body appreciation and facets of positive self-beliefs and positive mental health, respectively. Structural equation modelling showed that positive self-beliefs mediated the association between body appreciation and positive mental health after controlling for self-efficacy and resilience. This model was robust across women and men separately, and the mediational effects remained intact in sensitivity and robustness analyses. We discuss ways in which greater body appreciation may help individuals develop and maintain positive self-beliefs, which in turn shape mental health outcomes.
    Matched MeSH terms: Great Britain
  9. Thomas AG, Harrison S, Mogilski JK, Stewart-Williams S, Workman L
    Arch Sex Behav, 2024 Feb;53(2):611-627.
    PMID: 38030825 DOI: 10.1007/s10508-023-02749-6
    Polygamy is a form of "one-sided" consensually non-monogamous relationship where one person has multiple committed partners, each of whom is only involved with that one person. It was likely a reoccurring feature of ancestral mating that posed adaptive problems for our ancestors. Yet polygamy, and multi-partnering more generally, is understudied in Western cultures, raising questions about the existence of polygamous interest and whether this is calibrated adaptively to personal conditions. In two studies, we examined polygamous interest in two heterosexual online samples from the UK. In Study 1 (N = 393), modest interest was found for polygamous relationships overall. Men were six times more open to polygyny than women, but there was little sex difference in openness to polyandry. Further analysis revealed that all forms of multi-partnering were undesirable relative to singlehood and monogamy; however, consensual multi-partner relationships were less undesirable than non-consensual ones. Sex differences were largest for polygyny and arrangements where men had agreed access to a casual partner alongside a committed one, yet these were two of the most acceptable forms of multi-partnering when men and women's responses were combined. Sociosexuality positively predicted interest in most forms of multi-partnering. Study 2 (N = 735) focused on polygyny and added status-linked traits as predictors. The results of Study 1 were broadly replicated, though the status-linked traits did not predict polygynous interest specifically. Instead, sociosexuality and male intrasexual competitiveness uniquely predicted general interest in multi-partner relationships. Overall, interest in polygamy appears to emerge despite social discouragement and sex differences in interest track the relative costs and benefits associated with it. However, there is no strong evidence that polygamous interest is uniquely calibrated to personal conditions when compared to other forms of multi-partnering.
    Matched MeSH terms: Great Britain
  10. Skinner HG
    Proc R Soc Med, 1970 May;63(5):523-5.
    PMID: 5453443
    Matched MeSH terms: Great Britain
  11. Jahangir CA, Page DB, Broeckx G, Gonzalez CA, Burke C, Murphy C, et al.
    J Pathol, 2024 Mar;262(3):271-288.
    PMID: 38230434 DOI: 10.1002/path.6238
    Recent advances in the field of immuno-oncology have brought transformative changes in the management of cancer patients. The immune profile of tumours has been found to have key value in predicting disease prognosis and treatment response in various cancers. Multiplex immunohistochemistry and immunofluorescence have emerged as potent tools for the simultaneous detection of multiple protein biomarkers in a single tissue section, thereby expanding opportunities for molecular and immune profiling while preserving tissue samples. By establishing the phenotype of individual tumour cells when distributed within a mixed cell population, the identification of clinically relevant biomarkers with high-throughput multiplex immunophenotyping of tumour samples has great potential to guide appropriate treatment choices. Moreover, the emergence of novel multi-marker imaging approaches can now provide unprecedented insights into the tumour microenvironment, including the potential interplay between various cell types. However, there are significant challenges to widespread integration of these technologies in daily research and clinical practice. This review addresses the challenges and potential solutions within a structured framework of action from a regulatory and clinical trial perspective. New developments within the field of immunophenotyping using multiplexed tissue imaging platforms and associated digital pathology are also described, with a specific focus on translational implications across different subtypes of cancer. © 2024 The Authors. The Journal of Pathology published by John Wiley & Sons Ltd on behalf of The Pathological Society of Great Britain and Ireland.
    Matched MeSH terms: Great Britain
  12. Lim PY, Huxley JN, Willshire JA, Green MJ, Othman AR, Kaler J
    Prev Vet Med, 2015 Mar 1;118(4):370-7.
    PMID: 25579605 DOI: 10.1016/j.prevetmed.2014.12.015
    Recent studies have reported associations between lameness and body condition score (BCS) in dairy cattle, however the impact of change in the dynamics of BCS on both lameness occurrence and recovery is currently unknown. The aim of this longitudinal study was to investigate the effect of change in BCS on the transitions from the non-lame to lame, and lame to non-lame states. A total of 731 cows with 6889 observations from 4 UK herds were included in the study. Mobility score (MS) and body condition score (BCS) were recorded every 13-15 days from July 2010 until December 2011. A multilevel multistate discrete time event history model was built to investigate the transition of lameness over time. There were 1042 non-lame episodes and 593 lame episodes of which 50% (519/1042) of the non-lame episodes transitioned to the lame state and 81% (483/593) of the lame episodes ended with a transition to the non-lame state. Cows with a lower BCS at calving (BCS Group 1 (1.00-1.75) and Group 2 (2.00-2.25)) had a higher probability of transition from non-lame to lame and a lower probability of transition from lame to non-lame compared to cows with BCS 2.50-2.75, i.e. they were more likely to become lame and if lame, they were less likely to recover. Similarly, cows who suffered a greater decrease in BCS (compared to their BCS at calving) had a higher probability of becoming lame and a lower probability of recovering in the next 15 days. An increase in BCS from calving was associated with the converse effect, i.e. a lower probability of cows moving from the non-lame to the lame state and higher probability of transition from lame to non-lame. Days in lactation, quarters of calving and parity were associated with both lame and non-lame transitions and there was evidence of heterogeneity among cows in lameness occurrence and recovery. This study suggests loss of BCS and increase of BCS could influence the risk of becoming lame and the chance of recovery from lameness. Regular monitoring and maintenance of BCS on farms could be a key tool for reducing lameness. Further work is urgently needed in this area to allow a better understanding of the underlying mechanisms behind these relationships.
    Matched MeSH terms: Great Britain/epidemiology
  13. Tullo ES, Young TJ
    Int Psychogeriatr, 2014 Jan;26(1):165-71.
    PMID: 24135153 DOI: 10.1017/S1041610213001737
    BACKGROUND: The changing demographics of societies mean that medical students worldwide must be sufficiently prepared to care competently for patients with dementia through development of appropriate knowledge, skills, and attitudes. No previous research had explored undergraduate medical students' attitudes toward people with dementia.
    METHODS: An adapted version of the Approaches to Dementia Questionnaire (ADQ) was completed by 501 medical undergraduates in years 1, 3, and 5 of their degree programs in the UK and Malaysia. Non-parametric statistical analysis focused on any differences between year groups and geographical locations.
    RESULTS: The mean ADQ response indicated a generally positive attitude across the sample, comparable with other healthcare professionals previously surveyed. Year 3 and year 5 students expressed significantly more positive attitudes than year 1 students. Year 1 students based in the UK expressed significantly more positive attitudes than year 1 student based in Malaysia, but there were no significant differences between year 3 students based in different locations.
    CONCLUSION: The more positive attitudes found amongst year 3 and year 5 students compared to year 1 may be a result of teaching emphasizing a person-centered approach. The differences between entry-level students from Malaysia and the UK may reflect variance in cultural norms and expectations, or the ADQ's "Western" origin. Medical schools aiming to equip students with dementia-specific skills and knowledge can draw on the generally positive attitudes found in this study.
    Matched MeSH terms: Great Britain/epidemiology
  14. Khiun LK
    PMID: 20836261
    Matched MeSH terms: Great Britain/ethnology
  15. Veerapen K, Mangat G, Watt I, Dieppe P
    Br J Rheumatol, 1993 Jul;32(7):541-5.
    PMID: 8339122
    Seventy consecutive patients with definite or classical RA attending a University Hospital Rheumatology Clinic in Malaysia, were compared with an age, sex, disease duration matched group of RA patients seen in a British University Hospital. There were no differences in measures of disease activity, overall functional status or serological status in the two groups. However significant differences were seen in both the articular and extra-articular manifestations of the disease in the two countries. British patients had more severe disease in the feet, and a higher prevalence of nodules, vasculitis and pulmonary fibrosis. The Malaysian population had fewer erosions, more frequent involvement of the wrists and cervical spine, and a much higher incidence of secondary sicca syndrome. Radiographic changes were generally milder in Malaysian patients. Possible reasons for these differences in the expression of RA in the two countries are discussed.
    Matched MeSH terms: Great Britain/epidemiology
  16. Voracek M, Loibl LM, Swami V, Vintilă M, Kõlves K, Sinniah D, et al.
    Suicide Life Threat Behav, 2008 Dec;38(6):688-98.
    PMID: 19152299 DOI: 10.1521/suli.2008.38.6.688
    The genetics of suicide is increasingly recognized and relevant for mental health literacy, but actual beliefs may lag behind current knowledge. We examined such beliefs in student samples (total N = 686) from Estonia, Malaysia, Romania, the United Kingdom, and the United States with the Beliefs in the Inheritance of Risk Factors for Suicide Scale. Cultural effects were small, those of key demographics nil. Several facets of construct validity were demonstrated. Marked differences in perceived plausibility of evidence about the genetics of suicide according to research design, observed in all samples, may be of general interest for investigating lay theories of abnormal behavior and communicating behavioral and psychiatric genetic research findings.
    Matched MeSH terms: Great Britain/epidemiology
  17. Xiao B, Deng X, Ng EY, Allen JC, Lim SY, Ahmad-Annuar A, et al.
    JAMA Neurol, 2018 01 01;75(1):127-128.
    PMID: 29131875 DOI: 10.1001/jamaneurol.2017.3363
    Matched MeSH terms: Great Britain/epidemiology
  18. Aladwani M, Lophatananon A, Robinson F, Rahman A, Ollier W, Kote-Jarai Z, et al.
    PLoS One, 2020;15(9):e0238928.
    PMID: 32941451 DOI: 10.1371/journal.pone.0238928
    INTRODUCTION: Previous evidence has suggested a relationship between male self-reported body size and the risk of developing prostate cancer. In this UK-wide case-control study, we have explored the possible association of prostate cancer risk with male self-reported body size. We also investigated body shape as a surrogate marker for fat deposition around the body. As obesity and excessive adiposity have been linked with increased risk for developing a number of different cancers, further investigation of self-reported body size and shape and their potential relationship with prostate cancer was considered to be appropriate.

    OBJECTIVE: The study objective was to investigate whether underlying associations exist between prostate cancer risk and male self-reported body size and shape.

    METHODS: Data were collected from a large case-control study of men (1928 cases and 2043 controls) using self-administered questionnaires. Data from self-reported pictograms of perceived body size relating to three decades of life (20's, 30's and 40's) were recorded and analysed, including the pattern of change. The associations of self-identified body shape with prostate cancer risk were also explored.

    RESULTS: Self-reported body size for men in their 20's, 30's and 40's did not appear to be associated with prostate cancer risk. More than half of the subjects reported an increase in self-reported body size throughout these three decades of life. Furthermore, no association was observed between self-reported body size changes and prostate cancer risk. Using 'symmetrical' body shape as a reference group, subjects with an 'apple' shape showed a significant 27% reduction in risk (Odds ratio = 0.73, 95% C.I. 0.57-0.92).

    CONCLUSIONS: Change in self-reported body size throughout early to mid-adulthood in males is not a significant risk factor for the development of prostate cancer. Body shape indicative of body fat distribution suggested that an 'apple' body shape was protective and inversely associated with prostate cancer risk when compared with 'symmetrical' shape. Further studies which investigate prostate cancer risk and possible relationships with genetic factors known to influence body shape may shed further light on any underlying associations.

    Matched MeSH terms: Great Britain/epidemiology
  19. Head MG, Fitchett JR, Newell ML, Scott JAG, Clarke SC, Atun R
    Lancet Infect Dis, 2014 Nov;14(11):1037-1038.
    PMID: 25444398 DOI: 10.1016/S1473-3099(14)70949-1
    Matched MeSH terms: Great Britain/epidemiology
  20. Lee JK, Gregson C, Janssen SM, Estudillo AJ
    Q J Exp Psychol (Hove), 2023 Aug;76(8):1724-1739.
    PMID: 36394361 DOI: 10.1177/17470218221142158
    The self-face advantage (SFA) is reflected through a faster recognition of a self-face compared with familiar and unfamiliar faces. Nevertheless, as Westerners and East Asians tend to present differences in self-concept styles, it is possible that the SFA is modulated by culture. The present study explored this possibility using a visual search task. British Caucasians and Malaysian Chinese participants were asked to search for frontal view images of self, friend, and unfamiliar faces among an array of unfamiliar faces. Regardless of race, participants were more accurate and faster in searching for the own face and friend's face compared with an unfamiliar face, with no differences in the search between the own and friend's face, and these findings could not be accounted by the cultural differences in self-concept (i.e., operationalised by scores from the Independent and Interdependent Self-Concept Scale and the Horizontal and Vertical Individualism and Collectivism Scale). Altogether our results suggest that culture does not modulate the SFA and that this effect is better explained by a familiar face advantage.
    Matched MeSH terms: Great Britain/ethnology
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