Displaying publications 141 - 160 of 1053 in total

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  1. Ismail AH, Munro KJ, Armitage CJ, Dawes PD
    Int J Audiol, 2019 02;58(2):63-76.
    PMID: 30646766 DOI: 10.1080/14992027.2018.1531154
    OBJECTIVE: To conduct a systematic review of the evidence in relation to what hearing healthcare professionals do during hearing aid consultations and identifying which behaviours promote hearing aid use and benefit among adult patients.

    DESIGN: Searches were performed in electronic databases MEDLINE, EMBASE, CINAHL, PsycInfo, Web of Science, PubMed and Google Scholar. The Crowe Critical Appraisal Tool and Melnyk Levels of Evidence were used to assess quality and level of evidence of eligible studies. Behaviours of hearing healthcare professionals were summarised descriptively.

    STUDY SAMPLE: 17 studies met the inclusion criteria.

    RESULTS: Twelve studies described behaviours of audiologists and five studies were intervention studies. Audiologists were typically task- or technically-oriented and/or dominated the interaction during hearing aid consultations. Two intervention studies suggested that use of motivational interviewing techniques by audiologists may increase hearing aid use in patients.

    CONCLUSIONS: Most studies of clinicians' behaviours were descriptive, with very little research linking clinician behaviour to patient outcomes. The present review sets the research agenda for better-controlled intervention studies to identify which clinician behaviours better promote patient hearing aid outcomes and develop an evidence base for best clinical practice.

  2. Nissapatorn V, Lee C, Quek KF, Abdullah KA
    Jpn J Infect Dis, 2003 Oct-Dec;56(5-6):187-92.
    PMID: 14695428
    We retrospectively reviewed 419 HIV/AIDS patients in Hospital Kuala Lumpur from 1994 to 2001. In the male group, the age range was 20-74, with a mean age 37 years, while in the female group it was 17-63, with a mean age of 33 years. With regard to age group, it was found that the preponderant age group was 25-34 years. The majority of male subjects were Chinese (52.5%), single (56.3%), and unemployed (55.1%), whereas the females were Malay (42.3%), married (79.5%), and non-laborer (64.1%). Also, both groups resided in Kuala Lumpur and had heterosexual contact as the leading cause of HIV transmission. More than half of the patients had CD4 cell counts of <200 cells/cumm. We found that the acquisition of HIV infection via intravenous drug use (IDU) was directly related to the incidence of tuberculosis infection (P < 0.05). Further analysis showed HIV-related tuberculosis with IDU was also dependently correlated with occupational status (unemployed) (P < 0.05). The four main AIDS-defining diseases include tuberculosis (48%), Pneumocystis carinii pneumonia (13%), toxoplasmic encephalitis (11%), and cryptococcal meningitis (7%); in addition, 53% of these patients were found to have CD4 cell counts of less than 200 cells/cumm at the time of diagnosis.
  3. Faudzi FNM, Armitage CJ, Bryant C, Brown LJE
    Res Aging, 2019 07;41(6):549-574.
    PMID: 30700233 DOI: 10.1177/0164027518825117
    The aim of this study was to describe and systematically evaluate the psychometric properties of attitudes to aging measures that have been validated in adults younger than 60 years. Studies were assessed for methodological quality using the COnsensus-based Standards for the selection of health Measurement INstruments. Best evidence synthesis was performed to summarize the levels of evidence. Systematic searching yielded 21 articles, relating to 10 different measures. Some instruments were validated only in middle-aged and older people, while others were validated in a wider age range. Measures differed in whether their items related to participants' own experiences of aging, their anticipated future aging, and/or aging in general. None of the measures had had all of its psychometric properties assessed. The Expectations Regarding Ageing-12 and the Anxiety About Ageing Scale received positive ratings for the greatest number of psychometric properties, but capture different constructs, and may be differentially suited to different age groups of younger adults.
  4. Ho CC, Singam P, Hong GE, Zainuddin ZM
    Asian J Androl, 2011 Jul;13(4):537-42.
    PMID: 21643001 DOI: 10.1038/aja.2010.135
    Sex has always been a taboo subject in Asian society. However, over the past few years, awareness in the field of men's sexual health has improved, and interest in sexual health research has recently increased. The epidemiology and prevalence of erectile dysfunction, hypogonadism and premature ejaculation in Asia are similar in the West. However, several issues are specific to Asian males, including culture and beliefs, awareness, compliance and the availability of traditional/complementary medicine. In Asia, sexual medicine is still in its infancy, and a concerted effort from the government, relevant societies, physicians and the media is required to propel sexual medicine to the forefront of health care.
  5. Voo CLY, Yeo DET, Chong KP, Rodrigues KF
    Microbiol Resour Announc, 2020 Jan 02;9(1).
    PMID: 31896636 DOI: 10.1128/MRA.01240-19
    Basal stem rot (BSR) disease on Elaeis guineens is known to be caused by members of the pathogenic fungal genus Ganoderma, especially the species Ganoderma boninense This species affects oil palm plantation in Sabah, Malaysia. The genome sequence (52.28 Mbp) will add to the representation of this genus, especially in regard to BSR disease.
  6. Mohamed R, Bullen C, Hairi FM, Nordin ASA
    Tob Induc Dis, 2021;19:63.
    PMID: 34413718 DOI: 10.18332/tid/140089
    INTRODUCTION: Tobacco causes more than 8 million deaths each year. Behavioral interventions such as group therapy, which provides counselling for smoking cessation, can be delivered in group form and smokers who receive cessation counselling are more likely to quit smoking compared to no assistance. We review the evidence of group-based counselling for smoking cessation for smokers in Asian countries.

    METHODS: The review aims to determine the availability of group-based therapy for smoking cessation in Asian countries. The outcome measured was abstinence from smoking following group therapy. Electronic database searches in PubMed, OVID Medline, SCOPUS, Google Scholar, and PsycINFO, using keywords such as: 'smoking', 'cigarette', 'tobacco', 'nicotine', 'group therapy' and 'cessation' (smok*, *cigarette*, tobacco, nicotine, group therap*, cessation) were used. The results were reported following PRISMA and PROSPERO guidelines. Review Manager was used for data analysis.

    RESULTS: A total of 21251 records were retrieved for screening the abstracts. In all, 300 articles for review were identified and assessed for eligibility. Nine articles, including Cochrane reviews, randomized control trials, cohort, observational and cross-sectional studies, were included in the final review. There were three observational qualitative studies, two prospective cohort studies, two crosssectional studies, one non-randomized quasi-experimental study and a single cluster-randomized, controlled trial. Group therapy was found to significantly increase the abstinence rate. Group therapy provided at the workplace, smoking cessation services, availability of pharmacotherapy, and socioeconomic status, appear to be key factors determining success.

    CONCLUSIONS: Evidence of the use of group therapy for smoking cessation in Asian countries is still lacking despite publications in the Western population showed that group therapy was effective. Further research on group-based interventions for smoking cessation in Asian countries is required and direct one-to-one comparisons between group therapy and individual therapy for smokers who want to quit smoking, are needed.

  7. Faudzi FNM, Armitage CJ, Bryant C, Brown LJE
    Aging Ment Health, 2020 10;24(10):1620-1626.
    PMID: 31099260 DOI: 10.1080/13607863.2019.1619167
    Objectives: More positive attitudes to aging are associated with better health and wellbeing outcomes. This study examined whether chronological age moderated relationships between attitudes to aging and wellbeing outcomes, and whether these relationships differ according to the specific attitudinal construct measured.Method: Participants were 911 adults aged 18-60 years (mean = 36.63 years). Attitudes to ageing were measured using the Malay Reactions to Ageing Questionnaire (M-RAQ), which focuses on respondents' anticipated reactions to being aged over 65 years, and the Malay Anxiety about Ageing Scale (M-AAS), which additionally captures respondents' fears and anxieties about current aging and older people. Wellbeing outcomes were measured using the Warwick- Edinburgh Mental Well-being Scale (WEMWBS) and the Satisfaction with Life Scale (SWLS).Results: More positive attitudes to ageing were associated with higher levels of wellbeing and life satisfaction after controlling for age, gender, education, and self-rated health. Age moderated the relationships between the M-AAS and wellbeing and life satisfaction, with stronger relationships in younger adults. No moderating effects of age were found for the M-RAQ.Conclusion: The difference in the moderating effects of age between measures suggests that the two attitudinal constructs captured by these two measures operate in different ways. In particular, the current emotional/anxiety components of attitudes to ageing may differentially affect wellbeing at different ages. This suggests that interventions aimed at the promotion of wellbeing through coping with aging-related anxieties might be particularly well-suited to younger adults, who may be less able to respond effectively to the anxieties they experience.
  8. Bush JT, Chan MC, Mohammed S, Schofield CJ
    Chembiochem, 2020 06 02;21(11):1647-1655.
    PMID: 31919953 DOI: 10.1002/cbic.201900719
    The hypoxia-inducible factors (HIFs) are key transcription factors in determining cellular responses involving alterations in protein levels in response to limited oxygen availability in animal cells. 2-Oxoglutarate-dependent oxygenases play key roles in regulating levels of HIF and its transcriptional activity. We describe MS-based proteomics studies in which we compared the results of subjecting human breast cancer MCF-7 cells to hypoxia or treating them with a cell-penetrating derivative (dimethyl N-oxalylglycine; DMOG) of the stable 2OG analogue N-oxalylglycine. The proteomic results are consistent with reported transcriptomic analyses and support the proposed key roles of 2OG-dependent HIF prolyl- and asparaginyl-hydroxylases in the hypoxic response. Differences between the data sets for hypoxia and DMOG might reflect context-dependent effects or HIF-independent effects of DMOG.
  9. Chen HL, Gibbins CN, Selvam SB, Ting KN
    Environ Pollut, 2021 Nov 15;289:117895.
    PMID: 34364115 DOI: 10.1016/j.envpol.2021.117895
    Microplastic pollution is widely recognised as a global issue, posing risks to natural ecosystems and human health. The combination of rapid industrial and urban development and relatively limited environmental regulation in many tropical countries may increase the amount of microplastic entering rivers, but basic data on contamination levels are lacking. This is especially the case in tropical South East Asian countries. In this paper, the abundance, composition and spatio-temporal variation of microplastic in the Langat River, Malaysia, were assessed, and the relationship between microplastic concentration and river discharge was investigated. Water samples were collected over a 12-month period from 8 sampling sites on the Langat, extending from forested to heavily urbanised and industrial areas. All 508 water samples collected over this period contained microplastic; mean concentration across all sites and times was 4.39 particles/L but extended up to 90.00 particles/L in some urban tributaries. Most microplastics were secondary in origin, and dominated by fibres. Microplastic counts correlated directly with river discharge, and counts increased and decreased in response to changes in flow. A time-integrated assessment of the microplastic load conveyed by the Langat suggested that the river is typically (50 % of the time) delivering around 5 billion particles per day to the ocean. The positive correlation between the concentration of microplastics and suspended sediments in the Langat suggested that continuously logging turbidity sensors could be used to provide better estimates of microplastic loads and improve assessment of human and ecological health risks.
  10. Olanrewaju A, AbdulAziz A, Preece CN, Shobowale K
    Clean Eng Technol, 2021 Dec;5:100277.
    PMID: 34604830 DOI: 10.1016/j.clet.2021.100277
    COVID-19 is the most critical health and safety risk facing the global construction sector. The COVID-19 crisis leads to a reduction in site productivity, has increased compliance costs, delayed projects and increased construction workers' exposure to risk and infections. However, as countries begin to ease lockdowns and restrictions, there is a need to examine the measures that the construction companies can take to ensure workers are "Covid-safe". This research developed a questionnaire instrument that included 24 Covid-preventive measures on construction sites. Isolating sick workers, conducting daily checks for COVID-19 symptoms, preventing hugging/handshaking at the site, displaying health advisory posters and info-graphics, and providing face masks to workers are seen to be the main measures towards keeping sites "Covid-safe". The Principal Component Analysis structured the 24 measures into 4 components. The 4 components explained about 73% of the model, namely hygiene and control, equipment and monitoring, awareness, and incentives. The results found that compliance costs of health and safety regulations to prevent COVID-19 will increase project cost by more than 20%, site productivity will be reduced by up to 50%, and the pandemic will have caused a 40% increase in skill shortages. Cluster analysis was performed to cluster the sites in terms of their exposure to COVID-19 risk. In order to examine the practicability of the findings, the model was validated with 4 case studies. It is asserted that the research findings have the potential to keep sites "Covid-safe", which helps construction companies increase productivity, reduce project costs, reduce claims, and deliver projects on schedule. This research is the first to examine measures to prevent the spread of COVID-19 on construction sites, and the findings hold critical theoretical and practical implications for future research on health and safety management.
  11. Das S, Suhaimi F, Ho C, Ho SE
    MyJurnal
    Diabetes mellitus (DM) is a metabolic disease which is characterized by hyperglycemia. There is either disturbance in insulin secretion or defective insulin action or even a combination of both. Usually, there are few confounding factors like genetic, obesity, sedentary life style, atherosclerosis, and even faulty dietary habits which lead or aggravate DM. Usually, the individual does not care and often the complications resulting from hyperglycaemia are fatal. Complications in DM involve the cardiovascular, musculoskeletal, endocrine, renal and neurological systems in the body. Treatment of diabetic complications is not only costly but it is also a burden on the affected families. The present review discusses the challenges faced in DM with special concern on diet and food habits. Knowledge of proper food consumption may also help an individual combat complication in DM and reduce the mortality and morbidity.
    Keywords: Diabetes mellitus; complications; food; habits; mortality; morbidity
  12. Yousef Kalafi E, Tan WB, Town C, Dhillon SK
    BMC Bioinformatics, 2016 Dec 22;17(Suppl 19):511.
    PMID: 28155722 DOI: 10.1186/s12859-016-1376-z
    BACKGROUND: Monogeneans are flatworms (Platyhelminthes) that are primarily found on gills and skin of fishes. Monogenean parasites have attachment appendages at their haptoral regions that help them to move about the body surface and feed on skin and gill debris. Haptoral attachment organs consist of sclerotized hard parts such as hooks, anchors and marginal hooks. Monogenean species are differentiated based on their haptoral bars, anchors, marginal hooks, reproductive parts' (male and female copulatory organs) morphological characters and soft anatomical parts. The complex structure of these diagnostic organs and also their overlapping in microscopic digital images are impediments for developing fully automated identification system for monogeneans (LNCS 7666:256-263, 2012), (ISDA; 457-462, 2011), (J Zoolog Syst Evol Res 52(2): 95-99. 2013;). In this study images of hard parts of the haptoral organs such as bars and anchors are used to develop a fully automated identification technique for monogenean species identification by implementing image processing techniques and machine learning methods.

    RESULT: Images of four monogenean species namely Sinodiplectanotrema malayanus, Trianchoratus pahangensis, Metahaliotrema mizellei and Metahaliotrema sp. (undescribed) were used to develop an automated technique for identification. K-nearest neighbour (KNN) was applied to classify the monogenean specimens based on the extracted features. 50% of the dataset was used for training and the other 50% was used as testing for system evaluation. Our approach demonstrated overall classification accuracy of 90%. In this study Leave One Out (LOO) cross validation is used for validation of our system and the accuracy is 91.25%.

    CONCLUSIONS: The methods presented in this study facilitate fast and accurate fully automated classification of monogeneans at the species level. In future studies more classes will be included in the model, the time to capture the monogenean images will be reduced and improvements in extraction and selection of features will be implemented.

  13. Wijedasa LS, Page SE, Evans CD, Osaki M
    Science, 2016 11 04;354(6312):562.
    PMID: 27811262
  14. Showen R, Dunson C, Woodman GH, Christopher S, Lim T, Wilson SC
    Mar Pollut Bull, 2018 Mar;128:496-507.
    PMID: 29571401 DOI: 10.1016/j.marpolbul.2018.01.029
    Results are presented of a demonstration of real-time fish blast location in Sabah, Malaysia using a networked hydroacoustic array based on the ShotSpotter gunshot location system. A total of six acoustic sensors - some fixed and others mobile - were deployed at ranges from 1 to 9 km to detect signals from controlled test blasts. This allowed the blast locations to be determined to within 60 m accuracy, and for the calculated locations to be displayed on a map on designated internet-connected computers within 10 s. A smaller three-sensor system was then installed near Semporna in Eastern Sabah that determined the locations of uncontrolled blasts set off by local fishermen. The success of these demonstrations shows that existing technology can be used to protect reefs and permit more effective management of blast fishing activity through improved detection and enforcement measures and enhanced community engagement.
  15. Lim CTS, Kalaiselvam T, Kitan N, Goh BL
    Clin Kidney J, 2018 Apr;11(2):265-269.
    PMID: 29644069 DOI: 10.1093/ckj/sfx086
    Background: Parathyroidectomy (PTX) is done in cases of secondary hyperparathyroidism from chronic kidney disease to improve renal osteodystrophy. Despite this widespread practice, clinical outcomes regarding the benefits of this procedure are still lacking. Most studies in the literature have opted to report the laboratory outcome instead. Our study aimed to evaluate the postoperative clinical course for patients who had undergone total PTX without autoimplantation.

    Methods and results: All patients who underwent PTX between January 2010 and February 2014 in a tertiary referral center were included in this study and followed up for 12 months. Laboratory outcome parameters include various preoperative and postoperative serial measurements of laboratory parameters. Patients' hospitalizations and mortality records post-PTX were also retrieved and recorded. In all, 90 patients were included in this study. The mean age was 48 ± 18 years. The majority of the patients (54.4%) were male and 90% were on hemodialysis. The mean duration of dialysis was 8.0 ± 5.0 years. Indications for PTX were symptomatic bone pain (95.6%), fractures (3.3%) and calciphylaxis (1.1%). Mean preoperative values for serum calcium, phosphate, alkaline phosphatase and intact parathyroid hormone (iPTH) were 2.40 ± 0.23mmol/L, 1.92 ± 0.51 mmol/L, 689.60 ± 708.50 U/L and 311.90 ± 171.94 pmol/L, respectively. The majority (92.2%) had all four glands removed and 92.2% of the glands showed hyperplasic changes. One year after PTX, 90 patients (100%) had serum iPTH <8 pmol/L and 28 patients (31%) had unmeasurable iPTH levels. A total of 15% of patients had hospitalizations for various reasons and of these, 50% were within 90 days. The mean hospital stay was 14.4 ± 18.6 days. The mortality rate was 4.4% and of these, 25% were in first 30 days. Causes of death were mainly from sepsis (75%) and acute coronary syndrome (25%). One patient (1.1%) had a relapse.

    Conclusions: Even though PTX markedly reduces postoperative serum iPTH levels, it carries with it significant risk of morbidity and mortality.

  16. Faudzi FNM, Armitage CJ, Bryant C, Brown LJE
    Assessment, 2020 09;27(6):1272-1284.
    PMID: 29649886 DOI: 10.1177/1073191118766400
    The aims of this study were to culturally adapt the Reactions to Ageing Questionnaire (RAQ) for a non-Western (Malay) population, and explore attitudes to ageing in relation to age, gender, and education. Eight new culturally relevant items were generated by asking Malay-speaking participants about their reactions to ageing. A Malay version of the extended 35-item RAQ was then administered to 911 Malaysian participants aged 18 to 60 years. Exploratory factor analysis revealed four factors. Three of the factors were similar to those identified in the original RAQ, while "Family and Religion" emerged as a new factor. More negative attitudes to ageing were observed in younger and female respondents. There were no effects of education. This culturally adapted RAQ exhibits robust psychometric properties, and could be used to assess attitudes to ageing in Malaysia and other Southeast Asian countries. Moreover, we have identified a "core set" of RAQ items that could be applicable worldwide.
  17. Lim TS, Shanmuganathan M, Wong I, Goh BL
    BMC Nephrol, 2017 Mar 29;18(1):108.
    PMID: 28356062 DOI: 10.1186/s12882-017-0540-7
    BACKGROUND: For peritoneal dialysis patients, the likelihood of conception is low and the probability of getting through the pregnancy successfully is even lower. Almost 60 years after the first reported case of a successful pregnancy in a dialysis patient, many issues concerning pregnancy in dialysis patients remain unresolved. Our patient's pregnancy is considered high risk as she has end stage renal failure and falls in the category of advance maternal age for pregnancy. We describe here the course of her uneventful pregnancy which we hope will contribute to the overall knowledge and management of pregnancy in elderly patients receiving peritoneal dialysis.

    CASE PRESENTATION: We report a successful elderly multigravid pregnancy, in a patient undergoing continuous ambulatory peritoneal dialysis (CAPD). Her pregnancy was detected early and she was closely managed by the nephrologist and obstetrician. She tolerated the same PD prescription throughout 36 weeks of pregnancy with daily ultrafiltration of 500-1500mls. Her blood pressure remained well controlled without the need of any antihypertensive medication. Her total Kt/V ranged from 1.93 to 2.73. Her blood parameters remained stable and she was electively admitted at 36 weeks for a trans-peritoneal lower segment caesarian section and bilateral tubal ligation.

    CONCLUSIONS: At the age of 42, our case is the oldest reported successful pregnancy in a patient on peritoneal dialysis. With careful counselling and meticulous follow up, we have shown that woman in the early stage of end stage renal failure can successfully deliver a full term baby without any complications. Therefore, these women should not be discourage from conceiving even if they are in advanced maternal age for pregnancy.

  18. Lu L, Dietrich CH, Webb MD, Zhang Y
    Zootaxa, 2019 May 13;4604(1):zootaxa.4604.1.7.
    PMID: 31717206 DOI: 10.11646/zootaxa.4604.1.7
    Two new genera, Malaysiapona gen. nov. and Chandrapona gen. nov. of Paraboloponina leafhoppers (Cicadellidae: Deltocephalinae: Drabescini) with their unusally developed aedeagal base are described from the Pacific (Malaysia). The following new species are also described with the new genera: Malaysiapona brevipenis sp. nov. from Sabah, M. filamenta sp. nov., from Sarawak and Chandrapona vespertilis sp. nov. from Sabah.
  19. Bello Tambawal A, Md Noor R, Salleh R, Chembe C, Oche M
    PLoS One, 2019;14(4):e0214664.
    PMID: 30946766 DOI: 10.1371/journal.pone.0214664
    A vehicular ad hoc network (VANET) is an emerging and promising wireless technology aimed to improve traffic safety and provide comfort to road users. However, the high mobility of vehicles and frequent topology changes pose a considerable challenge to the reliable delivery of safety applications. Clustering is one of the control techniques used in VANET to make the frequent topology changes less dynamic. Nevertheless, research has shown that most of the existing clustering algorithms focus on cluster head (CH) election with very few addressing other critical issues such as cluster formation and maintenance. This has led to unstable clusters which could affect the timely delivery of safety applications. In this study, enhanced weight-based clustering algorithm (EWCA) was developed to address these challenges. We considered any vehicle moving on the same road segment with the same road ID and within the transmission range of its neighbour to be suitable for the cluster formation process. This was attributed to the fact that all safety messages are expected to be shared among the vehicles within the vicinity irrespective of their relative speedto avoid any hazardous situation. To elect a CH, we identified some metrics on the basis of the vehicle mobility information. Each vehicle was associated with a predefined weight value based on its relevance. A vehicle with the highest weight value was elected as the primary cluster head (PCH). We also introduced a secondary cluster head (SeCH) as a backup to the PCH to improve the cluster stability. SeCH took over the leadership whenever the PCH was not suitable for continuing with the leadership. The simulation results of the proposed approach showed a better performance with an increase of approximately40%- 45% in the cluster stability when compared with the existing approaches. Similarly, cluster formation messages were significantly minimized, hence reducing the communication overhead to the system and improving the reliable delivery of the safety applications.
  20. Ahmad B, Serpell CJ, Fong IL, Wong EH
    Front Mol Biosci, 2020;7:76.
    PMID: 32457917 DOI: 10.3389/fmolb.2020.00076
    Obesity is now a widespread disorder, and its prevalence has become a critical concern worldwide, due to its association with common co-morbidities like cancer, cardiovascular diseases and diabetes. Adipose tissue is an endocrine organ and therefore plays a critical role in the survival of an individual, but its dysfunction or excess is directly linked to obesity. The journey from multipotent mesenchymal stem cells to the formation of mature adipocytes is a well-orchestrated program which requires the expression of several genes, their transcriptional factors, and signaling intermediates from numerous pathways. Understanding all the intricacies of adipogenesis is vital if we are to counter the current epidemic of obesity because the limited understanding of these intricacies is the main barrier to the development of potent therapeutic strategies against obesity. In particular, AMP-Activated Protein Kinase (AMPK) plays a crucial role in regulating adipogenesis - it is arguably the central cellular energy regulation protein of the body. Since AMPK promotes the development of brown adipose tissue over that of white adipose tissue, special attention has been given to its role in adipose tissue development in recent years. In this review, we describe the molecular mechanisms involved in adipogenesis, the role of signaling pathways and the substantial role of activated AMPK in the inhibition of adiposity, concluding with observations which will support the development of novel chemotherapies against obesity epidemics.
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