Displaying publications 141 - 160 of 293 in total

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  1. Cervical lipoblastoma: An uncommon presentation
    Jaafar R, Tang IP, Jong DE, Narihan MZ
    Ear Nose Throat J, 2015 Jul;94(7):E8-10.
    PMID: 26214680
    Lipoblastoma is extremely rare and mainly occurs in children younger than 3 years old. It is predominantly found in the extremities and trunk. Head and neck region occurrences are rare; only 4 such cases involving patients who presented with stridor have been previously reported. We report the fifth case of lipoblastoma of the neck with stridor in a 9-year-old girl, which had gradually worsened over the previous year. Imaging showed a retrotracheal mass extending superiorly to the thyroid level and inferiorly to below the carina of the trachea. Total resection of the tumor was performed, and the histopathologic findings were consistent with lipoblastoma. Postoperatively, the patient was well with no complications.
    Matched MeSH terms: Head
  2. The opposing roles of NOTCH signalling in head and neck cancer: a mini review
    Yap LF, Lee D, Khairuddin A, Pairan MF, Puspita B, Siar CH, et al.
    Oral Dis, 2015 Oct;21(7):850-7.
    PMID: 25580884 DOI: 10.1111/odi.12309
    NOTCH signalling can exert oncogenic or tumour suppressive effects in both solid and haematological malignancies. Similar to T-cell acute lymphoblastic leukaemia (T-ALL), early studies suggested a pro-tumorigenic role of NOTCH in head and neck squamous cell carcinoma (HNSCC), mainly based on the increased expression levels of the genes within the pathway. Recently, data from exome sequencing analyses unexpectedly pointed to a tumour suppressor role for NOTCH in HNSCC by identifying loss-of-function mutations in the NOTCH1 gene in a significant proportion of patients. These data have questioned the accepted role of NOTCH in HNSCC and the possible rationale of targeting NOTCH in this disease. This review summarises the current information on NOTCH signalling in HNSCC and discusses how this pathway can apparently exert opposing effects within the same disease.
    Matched MeSH terms: Head and Neck Neoplasms
  3. 3 Tesla magnetic resonance imaging noise in standard head and neck sequence does not cause temporary threshold shift in high frequency
    Lim EY, Tang IP, Peyman M, Ramli N, Narayanan P, Rajagopalan R
    Eur Arch Otorhinolaryngol, 2015 Nov;272(11):3109-13.
    PMID: 25205300 DOI: 10.1007/s00405-014-3232-y
    High acoustic noise level is one of the unavoidable side effects of 3 T magnetic resonance imaging (MRI). A case of hearing loss after 3 T MRI has been reported in this institution and hence this study. The objective of this study was to determine whether temporary threshold shift (TTS) in high frequency hearing occurs in patients undergoing 3 T MRI scans of the head and neck. A total of 35 patients undergoing head and neck 3 T MRI for various clinical indications were tested with pure tone audiometry in different frequencies including high frequencies, before and after the MRI scan. Any threshold change from the recorded baseline of 10 dB was considered significant. All patients were fitted with foamed 3 M earplugs before the procedure following the safety guidelines for 3 T MRI. The mean time for MRI procedure was 1,672 s (range 1,040-2,810). The noise dose received by each patient amounted to an average of 3,906.29% (1,415-9,170%). The noise dose was derived from a normograph used by Occupational Noise Surveys. This was calculated using the nomograph of L eq, L EX, noise dose and time. There was no statistically significant difference between the hearing threshold before and after the MRI procedures for all the frequencies (paired t test, P > 0.05). For patients using 3 M foamed earplugs, noise level generated by 3 T MRI during routine clinical sequence did not cause any TTS in high frequency hearing.
    Matched MeSH terms: Head and Neck Neoplasms/pathology*
  4. Anterolateral corridor approach to the infratemporal fossa and central skull base in maxillectomy: rationale and technical aspects
    McMahon JD, Crowther J, Taylor WM, Wong LS, Paterson T, Devine J, et al.
    Br J Oral Maxillofac Surg, 2015 Nov;53(9):814-9.
    PMID: 26212419 DOI: 10.1016/j.bjoms.2015.06.006
    We describe the technical aspects and report our clinical experience of a surgical approach to the infratemporal fossa that aims to reduce local recurrence after operations for cancer of the posterior maxilla. We tested the technique by operating on 3 cadavers and then used the approach in 16 patients who had posterolateral maxillectomy for disease that arose on the maxillary alveolus or junction of the hard and soft palate (maxillary group), and in 19 who had resection of the masticatory compartment and central skull base for advanced sinonasal cancer (sinonasal group). Early proximal ligation of the maxillary artery was achieved in all but one of the 35 patients. Access to the infratemporal fossa enabled division of the pterygoid muscles and pterygoid processes under direct vision in all cases. No patient in the maxillary group had local recurrence at median follow up of 36 months. Four patients (21%) in the sinonasal group had local recurrence at median follow up of 27 months. Secondary haemorrhage from the cavernous segment of the internal carotid artery resulted in the only perioperative death. The anterolateral corridor approach enables controlled resection of tumours that extend into the masticatory compartment.
    Matched MeSH terms: Head
  5. Analysis on the effect of the distances and inclination angles between human head and mobile phone on SAR
    Hossain MI, Faruque MR, Islam MT
    Prog Biophys Mol Biol, 2015 Nov;119(2):103-10.
    PMID: 25863147 DOI: 10.1016/j.pbiomolbio.2015.03.008
    The aim of this paper is to investigate the effects of the distances between the human head and internal cellular device antenna on the specific absorption rate (SAR). This paper also analyzes the effects of inclination angles between user head and mobile terminal antenna on SAR values. The effects of the metal-glass casing of mobile phone on the SAR values were observed in the vicinity of the human head model. Moreover, the return losses were investigated in all cases to mark antenna performance. This analysis was performed by adopting finite-difference time-domain (FDTD) method on Computer Simulation Technology (CST) Microwave Studio. The results indicate that by increasing the distance between the user head and antenna, SAR values are decreased. But the increase in inclination angle does not reduce SAR values in all cases. Additionally, this investigation provides some useful indication for future design of low SAR mobile terminal antenna.
    Matched MeSH terms: Head/radiation effects*
  6. Enteral glutamine supplementation in surgical patients with head and neck malignancy: A randomized controlled trial
    Azman M, Mohd Yunus MR, Sulaiman S, Syed Omar SN
    Head Neck, 2015 Dec;37(12):1799-807.
    PMID: 24992652 DOI: 10.1002/hed.23839
    Glutamine supplementation is a novel approach to perioperative nutritional management.
    Matched MeSH terms: Head and Neck Neoplasms/blood; Head and Neck Neoplasms/surgery*
  7. Fulltext Nasal Septal Angiofibroma in a Post-Menopausal Woman: A Rare Entity
    Ewe S, Dayana F, Fadzilah FM, Gendeh BS
    J Clin Diagn Res, 2015 Dec;9(12):MD03-5.
    PMID: 26816925 DOI: 10.7860/JCDR/2015/14921.6947
    Juvenile angiofibromas (JAs) are well-characterised in literature, arising typically in the posterolateral wall of the nasal cavity of young males. Numerous theories have been proposed to explain the occurrence of this unique and rare tumour. Angiofibromas originating in other sites within the head and neck have been described but this is exceedingly rare, constituting less than 2% of all diagnosed cases. Extranasopharyngeal angiofibroma is a rare lesion, and more importantly, controversial. It is not known whether it is actually a relative of the well-known JA that is seen exclusively in adolescent males. We present the case of a post-menopausal woman with unilateral nasal obstruction who was unexpectedly diagnosed as nasal septal angiofibroma.
    Matched MeSH terms: Head
  8. Fulltext Sound signatures and production mechanisms of three species of pipefishes (Family: Syngnathidae)
    Lim AC, Chong VC, Wong CS, Muniandy SV
    PeerJ, 2015;3:e1471.
    PMID: 26734507 DOI: 10.7717/peerj.1471
    Background. Syngnathid fishes produce three kinds of sounds, named click, growl and purr. These sounds are generated by different mechanisms to give a consistent signal pattern or signature which is believed to play a role in intraspecific and interspecific communication. Commonly known sounds are produced when the fish feeds (click, purr) or is under duress (growl). While there are more acoustic studies on seahorses, pipefishes have not received much attention. Here we document the differences in feeding click signals between three species of pipefishes and relate them to cranial morphology and kinesis, or the sound-producing mechanism. Methods. The feeding clicks of two species of freshwater pipefishes, Doryichthys martensii and Doryichthys deokhathoides and one species of estuarine pipefish, Syngnathoides biaculeatus, were recorded by a hydrophone in acoustic dampened tanks. The acoustic signals were analysed using time-scale distribution (or scalogram) based on wavelet transform. A detailed time-varying analysis of the spectral contents of the localized acoustic signal was obtained by jointly interpreting the oscillogram, scalogram and power spectrum. The heads of both Doryichthys species were prepared for microtomographical scans which were analysed using a 3D imaging software. Additionally, the cranial bones of all three species were examined using a clearing and double-staining method for histological studies. Results. The sound characteristics of the feeding click of the pipefish is species-specific, appearing to be dependent on three bones: the supraoccipital, 1st postcranial plate and 2nd postcranial plate. The sounds are generated when the head of the Dorichthyes pipefishes flexes backward during the feeding strike, as the supraoccipital slides backwards, striking and pushing the 1st postcranial plate against (and striking) the 2nd postcranial plate. In the Syngnathoides pipefish, in the absence of the 1st postcranial plate, the supraoccipital rubs against the 2nd postcranial plate twice as it is pulled backward and released on the return. Cranial morphology and kinesis produce acoustic signals consistent with the bone strikes that produce sharp energy spikes (discrete or merged), or stridulations between bones that produce repeated or multimodal sinusoidal waveforms. Discussion. The variable structure of the sound-producing mechanism explains the unique acoustic signatures of the three species of pipefish. The differences in cranial bone morphology, cranial kinesis and acoustic signatures among pipefishes (and seahorses) could be attributed to independent evolution within the Syngnathidae, which warrants further investigation.
    Matched MeSH terms: Head
  9. Fulltext Metamaterial-Embedded Low SAR PIFA for Cellular Phone
    Faruque MR, Hossain MI, Misran N, Singh M, Islam MT
    PLoS One, 2015;10(11):e0142663.
    PMID: 26599584 DOI: 10.1371/journal.pone.0142663
    A metamaterial-embedded planar inverted-F antenna (PIFA) is proposed in this study for cellular phone applications. A dual-band PIFA is designed to operate both GSM 900 MHz and DCS 1800 MHz. The ground plane of a conventional PIFA is modified using a planar one-dimensional metamaterial array. The investigation is performed using the Finite Integration Technique (FIT) of CST Microwave Studio. The performance of the developed antenna was measured in an anechoic chamber. The specific absorption rate (SAR) values are calculated considering two different holding positions: cheek and tilt. The SAR values are measured using COMOSAR measurement system. Good agreement is observed between the simulated and measured data. The results indicate that the proposed metamaterial-embedded antenna produces significantly lower SAR in the human head compared to the conventional PIFA. Moreover, the modified antenna substrate leads to slight improvement of the antenna performances.
    Matched MeSH terms: Head/radiation effects*
  10. A new species of moray eel (Anguilliformes: Muraenidae) from Taiwan, with comments on related elongate unpatterned species
    Loh KH, Shao KT, Ho HC, Lim PE, Chen HM
    Zootaxa, 2015;4060:30-40.
    PMID: 26701587 DOI: 10.11646/zootaxa.4060.1.5
    The following nine elongate unpatterned muraenid species of the subfamily Muraeninae, including one new species, are recognized from Taiwan and adjacent waters: Gymnothorax albimarginatus (Temminck & Schlegel), G. dorsalis Seale, G. melanosomatus Loh, Shao & Chen, G. phasmatodes (Smith), G. prolatus Sasaki & Amaoka, G. sagmacephalus Böhlke, Pseudechidna brummeri (Bleeker), Strophidon sathete (Hamilton) and G. pseudomelanosomatus new species, described from two specimens. This new moray eel is distinguished from its similar species, G. melanosomatus, by the following features: grey brown body (vs. black), snout length 20.5% (vs. 17.8%) of head length, smaller eye diameter 8.2% (vs. 10.0%) of head length; preanal length 49.5% (vs. 58.5%) total length, and preanal vertebrae 89-89 (vs. 105-109). Phylogenetic relationships of the nine species were examined using nucleotide sequence data from partial sequences of mitochondrial ND5 gene (600 bp), and seven species form COI (600 bp). The genetic analyses suggest that G. pseudomelanosomatus is distinct from G. melanosomatus and the other six species of Gymnothorax. Morphological features and mitogenetic affinities strongly suggest that "G." dorsalis should be placed in Strophidon rather than in Gymnothorax. The results also suggest that employment of ND5 and COI gene sequences are rather useful for identification of species and for obtaining reasonable insights into the phylogeny of the muraenid species.
    Matched MeSH terms: Head
  11. Comparison of Serum Fucose Levels in Leukoplakia and Oral Cancer Patients
    Rai NP, Anekar J, Shivaraja Shankara YM, Divakar DD, Al Kheraif AA, Ramakrishnaiah R, et al.
    Asian Pac J Cancer Prev, 2015;16(17):7497-500.
    PMID: 26625751
    BACKGROUND: Tumor markers, designated as a broad group of substances produced by malignancies, could be in the form of biochemical substances, immunological substances, cell surface changes and genetic alterations. Cancer, a disorder of cellular behavior is characterized by alteration of serum glycoproteins. L-fucose, a hexose, which is the terminal sugar in most of the plasma glycoproteins, may be useful as a tumor marker for the detection, monitoring and prognostic assessment of malignancies. The aim of the study was to ascertain the role of serum fucose as a biomarker for early detection of oral cancer and to compare serum fucose levels in healthy controls, leukoplakia and oral cancer patients.

    MATERIALS AND METHODS: The study included 60 (100.0%) subjects, who were grouped as 20 (33.3%) control subjects, 20 (33.3%) squamous cell carcinoma patients and 20 (33.3%) leukoplakia patients. Fucose estimation was done using UV-visible spectrophotometry based on the method as adopted by Winzler using cysteine reagent. The results were analyzed statistically using ANOVA with Bonferroni post hoc tests.

    RESULTS: Results showed a high significance in serum fucose in oral squamous cell carcinoma (OSCC) and leukoplakia subjects compared to normal controls. There was a gradual increase in the values noted from control to leukoplakia and to squamous cell carcinoma.

    CONCLUSIONS: Estimation of serum fucose may be a reliable marker and can be used as an effective diagnostic biomarker in oral squamous cell carcinoma patients.

    Matched MeSH terms: Head and Neck Neoplasms/blood*; Head and Neck Neoplasms/diagnosis
  12. Fulltext The aerodynamic cost of head morphology in bats: maybe not as bad as it seems
    Vanderelst D, Peremans H, Razak NA, Verstraelen E, Dimitriadis G, Dimitriadis G
    PLoS One, 2015;10(3):e0118545.
    PMID: 25739038 DOI: 10.1371/journal.pone.0118545
    At first sight, echolocating bats face a difficult trade-off. As flying animals, they would benefit from a streamlined geometric shape to reduce aerodynamic drag and increase flight efficiency. However, as echolocating animals, their pinnae generate the acoustic cues necessary for navigation and foraging. Moreover, species emitting sound through their nostrils often feature elaborate noseleaves that help in focussing the emitted echolocation pulses. Both pinnae and noseleaves reduce the streamlined character of a bat's morphology. It is generally assumed that by compromising the streamlined charactered of the geometry, the head morphology generates substantial drag, thereby reducing flight efficiency. In contrast, it has also been suggested that the pinnae of bats generate lift forces counteracting the detrimental effect of the increased drag. However, very little data exist on the aerodynamic properties of bat pinnae and noseleaves. In this work, the aerodynamic forces generated by the heads of seven species of bats, including noseleaved bats, are measured by testing detailed 3D models in a wind tunnel. Models of Myotis daubentonii, Macrophyllum macrophyllum, Micronycteris microtis, Eptesicus fuscus, Rhinolophus formosae, Rhinolophus rouxi and Phyllostomus discolor are tested. The results confirm that non-streamlined facial morphologies yield considerable drag forces but also generate substantial lift. The net effect is a slight increase in the lift-to-drag ratio. Therefore, there is no evidence of high aerodynamic costs associated with the morphology of bat heads.
    Matched MeSH terms: Head/anatomy & histology*
  13. Fulltext Fatal motorcycle crashes: a growing public health problem in Cambodia
    Roehler DR, Ear C, Parker EM, Sem P, Ballesteros MF
    Int J Inj Contr Saf Promot, 2015;22(2):165-71.
    PMID: 24499413 DOI: 10.1080/17457300.2013.876050
    This study examines the risk characteristics of fatal motorcycle crashes in Cambodia over a 5-year period (2007-2011). Secondary data analyses were conducted using the Cambodia Road Crash and Victim Information System, the only comprehensive and integrated road crash surveillance system in the country. Researchers from the Centers for Disease Control and Prevention and Handicap International found that (1) males are dying in motorcycle crashes roughly seven times more frequently than females; (2) motorcyclist fatalities increased by about 30% from 2007 to 2011; (3) the motorcyclist death rates per 100,000 population increased from 7.4 to 8.7 deaths from 2007 to 2011; and (4) speed-related crashes and not wearing motorcycle helmet were commonly reported for motorcyclist fatalities at approximately 50% and over 80% through the study years, respectively. Additionally, this study highlights that Cambodia has the highest motorcycle death rate in South-East Asia, far surpassing Thailand, Malaysia, and Myanmar. By recognising the patterns of fatal motorcycle crashes in Cambodia, local road-safety champions and stakeholders can design targeted interventions and preventative measures to improve road safety among motorcyclists.
    Matched MeSH terms: Head Protective Devices/trends; Head Protective Devices/utilization*
  14. Fulltext Three squamous cell carcinomas of different sites in three years: A mere coincidence?
    Azman M, Mohd Yunus MR
    Indian J Cancer, 2015 Apr-Jun;52(2):201-2.
    PMID: 26853404 DOI: 10.4103/0019-509X.175817
    Matched MeSH terms: Head and Neck Neoplasms/pathology*; Head and Neck Neoplasms/radiography*; Head and Neck Neoplasms/therapy
  15. Treatment outcome for head and neck squamous cell carcinoma in a developing country: University Malaya Medical Centre, Malaysia from 2003-2010
    Wong YF, Yusof MM, Wan Ishak WZ, Alip A, Phua VC
    Asian Pac J Cancer Prev, 2015;16(7):2903-8.
    PMID: 25854381
    BACKGROUND: Head and neck cancer (HNC) is the eighth most common cancer as estimated from worldwide data. The incidence of HNC in Peninsular Malaysia was reported as 8.5 per 100,000 population. This study was aimed to determine the treatment outcomes for HNC patients treated in the Oncology Unit of University Malaya Medical Centre (UMMC).

    MATERIALS AND METHODS: All newly diagnosed patients with squamous cell carcinoma of head and neck (HNSCC) referred for treatment to the Oncology Unit at UMMC from 2003-2010 were retrospectively analyzed. Treatment outcomes were 5-year overall survival (OS), cause specific survival (CSS), loco-regional control (LRC) and radiotherapy (RT) related side effects. Kaplan-Meier and log rank analyses were used to determine survival outcomes, stratified according to American Joint Committee on Cancer (AJCC) stage.

    RESULTS: A total of 130 cases were analysed. Most cases (81.5%) were at late stage (AJCC III-IVB) at presentation. The 5-year OS for the whole study population was 34.4% with a median follow up of 24 months. The 5-year OS according to AJCC stage was 100%, 48.2%, 41.4% and 22.0% for stage I, II, III and IVA-B, respectively. The 5-year overall CSS and LCR were 45.4% and 55.4%, respectively. Late effects of RT were documented in 41.4% of patients. The most common late effect was xerostomia.

    CONCLUSIONS: The treatment outcome of HNSCC at our centre is lagging behind those of developed nations. Efforts to increase the number of patients presenting in earlier stages, increase in the use of combined modality treatment, especially concurrent chemoradiotherapy and implementation of intensity modulated radiotherapy, may lead to better outcomes for our HNC patients.

    Matched MeSH terms: Head and Neck Neoplasms/mortality; Head and Neck Neoplasms/pathology; Head and Neck Neoplasms/therapy*
  16. A review of Billaea Robineau-Desvoidy of the eastern Palearctic and Oriental regions (Diptera: Tachinidae)
    Zhang CT, Shima H, Wang Q, Tschorsnig HP
    Zootaxa, 2015;3949(1):1-40.
    PMID: 25947790 DOI: 10.11646/zootaxa.3949.1.1
    The species of Billaea Robineau-Desvoidy (Diptera, Tachinidae) from the eastern Palearctic and Oriental regions are        revised. Ten described species are recognized, viz. B. atkinsoni (Baranov) (new records for Japan, Laos, Malaysia, Pakistan and Thailand), B. ficorum (Townsend), B. fortis (Rondani), B. impigra Kolomiets (new record for China), B. kolomyetzi Mesnil, B. malayana Malloch, B. morosa Mesnil, B. robusta Malloch, B. steini (Brauer et Bergenstamm) and B. triangulifera (Zetterstedt) and nine species are described as new to science, B. brevicauda Zhang et Shima sp. nov.       (China), B. carinata Zhang et Shima sp. nov. (China), B. chinensis Zhang et Shima sp. nov. (China and Vietnam), B. flava Zhang et Wang sp. nov. (China), B. kurahashii Zhang et Shima sp. nov. (Laos and Thailand), B. micronychia Zhang et Shima sp. nov. (China and Japan; previously misidentified from China as B. irrorata (Meigen)), B. papei Zhang et Shima sp. nov. (Malaysia), B. setigera Zhang et Shima sp. nov. (China) and B. verticalis Shima et Zhang sp. nov. (China). Billaea fasciata (Townsend, 1928) is treated as a junior synonym of B. ficorum (Townsend, 1916), syn. nov. Billaea irrorata is no longer recorded from the eastern Palearctic. A key to 19 species of Billaea from the eastern Palearctic and Oriental regions and 101 figures of male terminalia, bodies, heads and abdomens are given.
    Matched MeSH terms: Head
  17. Fulltext Simulating bio-composite cycling helmet performance through FEA and CFD approaches
    Mohd Naim Abdullah, Mustapha, F., Muda, M.K.H., Arrifin, M.K.A., Rafie, A.S.M., Shamsudin, M.A.
    Movement Health & Exercise, 2015;4(1):77-91.
    MyJurnal
    Finite Element Analysis (FEA) and Computational Fluid Dynamics (CFD) analysis were performed in this work in order to obtain the best design for safety and aerodynamic performance of the bicycle cycling helmet. FEA analysis was computed on two different helmet designs to determine the critical area subjected to impact. A pressure load was applied on the helmets’ outer surface to simulate oblique loading. The critical areas of the helmets were then highlighted and identified, enabling design improvements to be made on both designs. CFD analysis was then executed in order to obtain the lowest drag coefficient number in reducing the air resistance induced by both of the helmet designs, inherently increasing cyclist performance and ensuring competition success.
    Matched MeSH terms: Head Protective Devices
  18. Fulltext Prevalence of dysphagia in patients with head and neck cancer at dental clinic, Hospital USM
    Linn, Lynn Ko Wei, Nor Fatiyah Che M. Nasir, Norsila Abdul Wahab
    Archives of Orofacial Sciences, 2015;10(1):10-16.
    MyJurnal
    Prevalence of dysphagia is one of the important epidemiological data which will contribute to the proper planning and support the setting up of a swallowing rehabilitation clinic at this hospital. The present study aimed to determine the prevalence of dysphagia in patients with head and neck cancer (HNC) at Hospital Universiti Sains Malaysia (Hospital USM) from 2001-2010. In this institutional retrospective study, a total of 66 records were obtained comprising of 86.4% Malay patients, 9.1% Chinese, 1.5% Indians, and 3% other ethnic groups. These data were taken from the database of HNC patients seen at the dental clinic, Hospital USM between 2001 and 2010. Difficulty swallowing, frequent coughing during meal, choking, diet modification, and non-oral nutritional support were identified as signs and symptoms associated with dysphagia. Results showed that 59.1% of patients have had dysphagia before, during, or after the treatment of HNC. Data from the present study would be instrumental in increasing awareness among clinicians involved in patient care and it may help in planning the outline of management of dysphagia. Furthermore, it is anticipated to have implications for further research in swallowing and dysphagia.
    Study site: Dental clinics, Hospital Universiti Sains Malaysia (HUSM), Kelantan, Malaysia
    Matched MeSH terms: Head and Neck Neoplasms
  19. Fulltext Research and design of ergonomics rostrum
    Mohamad Norashraf Mohd Noh, Hari Krishnan, Roseni Abd Aziz, Raemy Md Zein, Noorul Azreen Azis
    Journal of Occupational Safety and Health, 2015;12(1):183-186.
    MyJurnal
    This invention is more on ergonomics scope. This ergonomics rostrum fulfills the ergonomics criteria especially
    when used while standing. The important parts in this invention are rostrum head and platform. The rostrum head is
    adjustable so the users can set the height of rostrum head for their suitability and comfort. Another important part in
    this invention is platform. The purpose of the platform is to help users reach the rostrum head. The platform can flip
    into the rostrum body. This invention can be used by anyone especially for Malaysian people because its designed was
    based on the Malaysian height.
    Matched MeSH terms: Head
  20. Fulltext A mouse model of weight-drop closed head injury: emphasis on cognitive and neurological deficiency
    Khalin I, Jamari NL, Razak NB, Hasain ZB, Nor MA, Zainudin MH, et al.
    Neural Regen Res, 2016 Apr;11(4):630-5.
    PMID: 27212925 DOI: 10.4103/1673-5374.180749
    Traumatic brain injury (TBI) is a leading cause of death and disability in individuals worldwide. Producing a clinically relevant TBI model in small-sized animals remains fairly challenging. For good screening of potential therapeutics, which are effective in the treatment of TBI, animal models of TBI should be established and standardized. In this study, we established mouse models of closed head injury using the Shohami weight-drop method with some modifications concerning cognitive deficiency assessment and provided a detailed description of the severe TBI animal model. We found that 250 g falling weight from 2 cm height produced severe closed head injury in C57BL/6 male mice. Cognitive disorders in mice with severe closed head injury could be detected using passive avoidance test on day 7 after injury. Findings from this study indicate that weight-drop injury animal models are suitable for further screening of brain neuroprotectants and potentially are similar to those seen in human TBI.
    Matched MeSH terms: Head Injuries, Closed
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