MyMedR

Fulltext Validation of The Malay Version Of Fagerstrom Test For Nicotine Dependence (FTND-M) Among a Group of Male Staffs in a University Hospital

Ng, C.G., Rusdi, A.R., Anne Yee, H.A.

Malaysian Journal of Psychiatry, 2011;20(1):1-7.

MyJurnal

Objective: The aim of this study was to evaluate the validity and reliability of the Malay version of the Fagerstrom Test for Nicotine Dependence (FTND-M) based on a group of male staffs in the hospital. This study will also determine whether an abbreviated version of the FTND-M can be used as a screening tool for nicotine dependence. Method: 107 male staffs participated in the study. They were given the FTND-M and Malay version of Mini-International Neuropsychiatric Interview (M.I.N.I.)-L component. Their carbon monoxide level measured in their breath by using exhaled air. One week later, these participants were again given FTND-M. Results: The discriminatory ability of FTND-M was good with AUC 0.74 (P2 with the sensitivity of 70.1%, specificity of 70%, PPV of 79.7% and NPV of 58.3%. The FTND-M had moderate internal consistency with a Cronbach’s alpha of 0.67. The testretest reliability after 1 week was fair (Spearman’s rho=0.5, p)

Fulltext Factorial validity and reliability of the simplified-Chinese version of Snaith-Hamilton pleasure scale: a study among depressed patients at an out-patient clinic in Malaysia

Anne, Yee, Huai, Seng Loh, Chong, Guan Ng

ASEAN Journal of Psychiatry, 2014;15(1):66-71.

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Objective: The Snaith-Hamilton Pleasure Scale (SHAPS) is a self-assessment scale designed to evaluate anhedonia in various psychiatric disorders. To facilitate its use in Malaysian settings, our current study aimed to examine the validity of the Simplified-Chinese translated version of the SHAPS (SHAPS-SC) in a group of subjects at a university out-patient clinic. Method: A total of 40 depressed patients were recruited in this cross sectional study. They were given both the Simplified Chinese and Malay versions of SHAPS, General Health Questionnaire 12 (GHQ-12) and Beck Depression Inventory (BDI) to assess their hedonic state, general mental health condition and level of depression. Results: Our study showed that SHAPS-SC had impressive internal consistency (Cronbach’s alpha 0.84) and concurrent validity, and fair parallel-forms reliability (Pearson’s correlation 0.39). Conclusion: SHAPS-SC demonstrated good psychometric properties in the evaluation of hedonic state among a group of Chinese speaking depressed patients in an out-patient setting. It is easy to administer and suitable as a valid and reliable questionnaire in assessing anhedonia among depressed patients in Malaysia. ASEAN Journal of Psychiatry, Vol. 15 (1): January - June 2014: 66-71.

Study site: psychiatric out-patient clinic, University
Malaya Medical Centre (UMMC)

Exhaled carbon monoxide levels among Malaysian male smokers with nicotine dependence

Guan NC, Ann AY

Southeast Asian J. Trop. Med. Public Health, 2012 Jan;43(1):212-8.

PMID: 23082572

We studied the use of exhaled carbon monoxide (CO) to identify nicotine dependence among adult Malaysian male smokers. We conducted a cross-sectional study among 107 male smoking staff at a university hospital. We measured their exhaled CO using a piCO+ Smokerlyzer and diagnosed nicotine dependence using a Mini-International Neuropsychiatric Interview (MINI). The optimal cut-off value for exhaled CO was determined. The correlation between exhaled CO level and the Fagerstrom Test for Nicotine Dependence (FTND) was also assessed. The mean exhaled CO level among subjects with nicotine dependence (15.78 ppm) was significantly higher than subjects without nicotine dependence (9.62 ppm). The cut-off value used to identify smokers with nicotine dependence was set at 10 ppm (specificity = 0.721, sensitivity = 0.731, positive predictive value = 0.817 and negative predictive value = 0.617). Psychometric properties were stable with various durations of smoking. Exhaled CO correlated positively with FTND scores (Pearson's rho = 0.398, p = 0.01). Our findings show exhaled CO can be used to identify nicotine dependence among adult Malaysian male smokers.

Fulltext Antidepressant induced Mania and Steroid Psychosis in a Patient with Bell’s Palsy

Tan, C.L., Anne Yee, H.A., Majid, S.M., Koh, O.H., Ng, C.G.

Malaysian Journal of Psychiatry, 2010;19(2):1-5.

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Steroid is commonly used for various connective tissue diseases and immunological related disorders. Psychiatric side effects are common in patient with systematic treatment of steroid. The reported prevalence ranges from 6% to 28%. Antidepressant-induced mania occurs when the mood of a patient switches to manic or hypomanic from depression after the use of antidepressant. We reported a case of a 55 year old lady, who presented with agitation and grandiosity after the treatment with antidepressant. She was initially diagnosed as having Bell’s palsy with unilateral facial muscle weakness. Oral prednisolone was prescribed for seven days where she became depressed, having auditory hallucination and delusion of guilt. She was then started on antidepressant where she became irritable, agitated and developed grandiose delusion. The antidepressant was withheld and she was started on atypical antipsychotic. Her condition improved and discharged well after three days of stay in the ward.

Factorial validity and reliability of the Malaysian simplified Chinese version of Multidimensional Scale of Perceived Social Support (MSPSS-SCV) among a group of university students

Guan NC, Seng LH, Hway Ann AY, Hui KO

Asia Pac J Public Health, 2015 Mar;27(2):225-31.

PMID: 23449622 DOI: 10.1177/1010539513477684

This study was aimed at validating the simplified Chinese version of the Multidimensional Scale of Perceived Support (MSPSS-SCV) among a group of medical and dental students in University Malaya. Two hundred and two students who took part in this study were given the MSPSS-SCV, the Medical Outcome Study social support survey, the Malay version of the Beck Depression Inventory, the Malay version of the General Health Questionnaire, and the English version of the MSPSS. After 1 week, these students were again required to complete the MSPSS-SCV but with the item sequences shuffled. This scale displayed excellent internal consistency (Cronbach's α = .924), high test-retest reliability (.71), parallel form reliability (.92; Spearman's ρ, P < .01), and validity. In conclusion, the MSPSS-SCV demonstrated sound psychometric properties in measuring social support among a group of medical and dental students. It could therefore be used as a simple screening tool among young educated Malaysian adolescents.

Social anhedonia in Malaysian schizophrenia patients and healthy participants

Balasingam K, Kanagasundram S, Ann AYH, Kasmuri K, Gooding DC

Asian J Psychiatr, 2023 Jan;79:103350.

PMID: 36462388 DOI: 10.1016/j.ajp.2022.103350

The reduced capacity for social and interpersonal interactions, social anhedonia, is an important aspect of various psychiatric disorders, especially schizophrenia-spectrum disorders. The goal of the present study was to validate a Malay translation of the adult version of the Anticipatory and Consummatory Interpersonal Pleasure Scale (ACIPS; Gooding and Pflum, 2014), a relatively short and easy to administer indirect measure of social anhedonia. This cross-sectional study included 95 (47 male, 48 female) schizophrenia patients and 300 (77 male, 223 female) healthy subjects. Participants were given Malay versions of the ACIPS, Snaith Hamilton Pleasure Scale (SHAPS-M), and Beck Depression Inventory (BDI-M). The ACIPS exhibited good internal consistency (Ordinal alpha = 0.966). Total ACIPS scores were inversely correlated with the BDI-M scores, and positively correlated with total SHAPS-M scores. Factor analysis yielded a three-factor solution which accounted for 52.06% of the variance. As expected, the schizophrenia patients scored significantly lower than the healthy community participants on the ACIPS, t(130) = 4.26, p

Fulltext Factorial validity and reliability of the Tamil version of multidimensional scale of perceived social support among a group of participants in university malaya medical centre, malaysia

Guan NC, Sulaiman AR, Seng LH, Ann AY, Wahab S, Pillai SK

Indian J Psychol Med, 2013 Oct;35(4):385-8.

PMID: 24379500 DOI: 10.4103/0253-7176.122234

This study was done to validate the Tamil version of Multidimensional Scale of Perceived Social Support (MSPSS-TV) among a group of Indian participants in University Malaya.

Duration of hypertension and antihypertensive agents in correlation with the phases of female sexual response cycle

Latif RA, Muhamad R, Ann AY, Sidi H, Nik Jaafar NR, Midin M, et al.

Compr Psychiatry, 2014 Jan;55 Suppl 1:S7-12.

PMID: 23206495 DOI: 10.1016/j.comppsych.2012.10.008

This cross-sectional study aimed to determine the construct of the phases of the female sexual response cycle (SRC) in women with hypertension and their association with the duration of hypertension and types of antihypertensive agents.

Association of brain-derived neurotrophic factor valine to methionine polymorphism with sexual dysfunction following selective serotonin reuptake inhibitor treatment in female patients with major depressive disorder

Nazree NE, Mohamed Z, Reynolds GP, Mohd Zain S, Masiran R, Sidi H, et al.

Asia Pac Psychiatry, 2016 Dec;8(4):260-268.

PMID: 27787964 DOI: 10.1111/appy.12210

INTRODUCTION: The occurrence of female sexual dysfunction (FSD) in patients with major depressive disorder (MDD) receiving selective serotonin reuptake inhibitors (SSRIs) treatment gives negative impacts on patients' quality of life and causes treatment discontinuation. We aimed to investigate whether genetic polymorphism of identified candidate gene is associated with FSD in our study population.

METHODS: This is a cross-sectional study. A total of 95 female patients with MDD who met the criteria of the study were recruited and were specifically assessed on the sexual function by trained psychiatrists. Patients' DNA was genotyped for BDNF Val66Met polymorphism using real-time polymerase chain reaction.

RESULTS: The prevalence of FSD in this study is 31.6%. In the FSD group, patients with problematic marriage were significantly more frequent compared with patients who did not have problematic marriage (P = 0.009). Significant association was detected in the lubrication domain with BDNF Val66Met polymorphism (P = 0.030) using additive genetic model, with even stronger association when using the recessive model (P = 0.013).

DISCUSSION: This study suggested that there was no significant association between BDNF Val66Met with FSD. However, this polymorphism is significantly associated with lubrication disorder in patients treated with SSRIs.

Fulltext Responding to COVID-19: Emerging Practices in Addiction Medicine in 17 Countries

Scheibein F, Stowe MJ, Arya S, Morgan N, Shirasaka T, Grandinetti P, et al.

Front Psychiatry, 2021;12:634309.

PMID: 33796034 DOI: 10.3389/fpsyt.2021.634309

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