STUDY DESIGN: Secondary analysis of a large dataset multi-country observational study.
METHODS: We used a four-pronged analysis approach to investigate whether personal history of infectious and parasitic diseases is related to self-reported health, measured with a single item.
RESULTS: Three of the four analyses found a small positive effect on self-reported health among those reporting a history of pathogen exposure. The meta-analysis found no support but large heterogeneity that was not reduced by two classifications of countries.
CONCLUSION: Personal history of infectious and parasitic diseases does not reduce self-reported health across a global sample.