Displaying publications 1 - 20 of 37 in total

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  1. Tan YA, Ng KC, Cheo SW, Low QJ, Chia YK
    QJM, 2020 07 01;113(7):517-518.
    PMID: 32191336 DOI: 10.1093/qjmed/hcaa099
    Matched MeSH terms: Endocarditis, Bacterial*
  2. Zamasry MS, Hilmi Z, Mohd Yusof MYP, Razali HSA, Nawawi H, Mahmood MS
    Trop Biomed, 2019 Dec 01;36(4):845-849.
    PMID: 33597456
    Infective endocarditis (IE) is a relatively uncommon disease, but has been challenging to diagnose over the years. With the increasing incidence, variety of causative agents and the resistance of microorganisms towards antibiotics, there is still an occurrence of sudden death due to undiagnosed IE. The most common microorganism causing IE is Staphylococcus aureus. However, there is increasing prevalence of other microorganisms causing IE. This case report highlights a case of sudden death due to IE caused by a rare pathogen, Streptococcus constellatus which belongs to the Streptococcus anginosus group (Milleri group). A study noted the crude incidence of IE in 6 world regions ranged between 1.5 and 11.6 cases per 100,000 people. To date, there has been no previous report on sudden death due to IE caused by Streptococcus constellatus in Malaysia, neither in the forensic nor clinical setting. This case report underlined the characteristics and pathological features of this microorganism. The increasing incidence and variety of causative organisms in IE are important public health issues. It is vital for future studies to examine the risk factors of IE related to Streptococcus constellatus, to enhance better understanding, insight and awareness regarding the course of this disease. This in turn may facilitate preventive measures to avoid morbidity and mortality from this condition.
    Matched MeSH terms: Endocarditis, Bacterial/diagnosis*; Endocarditis, Bacterial/microbiology
  3. Kareem BA, Kamarulzaman H, Koh GT
    Ann Thorac Surg, 2010 Nov;90(5):1703-5.
    PMID: 20971300 DOI: 10.1016/j.athoracsur.2010.04.105
    A 9-year-old boy with patent ductus arteriosus complicated by infective endocarditis had not responded to antibiotic therapy and was referred to our institution. He had persistent fever and a chest roentgenogram demonstrated the presence of left lung pneumonic consolidation. An echocardiogram showed the presence of large vegetation in the pulmonary artery at the ductal opening. We successfully performed an open ductal ligation with the aid of cardiopulmonary bypass through a sternotomy and proceeded to resect the vegetation. We completed the procedure with reconstruction of the pulmonary artery. The postoperative course was uneventful. The patient was discharged after a week.
    Matched MeSH terms: Endocarditis, Bacterial/surgery*
  4. Ng WH
    Med J Malaysia, 1981 Dec;36(4):205-8.
    PMID: 7334953
    The ability to visualise valvular vegetations by echocardiography is a significant advantage in the management oj patients with infective endocarditis. In this report the M-Mode and Cross-Sectional echocardiographic appearances oj infective endocarditis affecting the aortic valve are described. The uses and limitations of echocardiography are discussed.
    Matched MeSH terms: Endocarditis, Bacterial/diagnosis*
  5. Sharif JM, Raja Shahardin RZ, Sockalingam G
    J Indian Soc Pedod Prev Dent, 2020 7 3;38(2):126-131.
    PMID: 32611857 DOI: 10.4103/JISPPD.JISPPD_235_18
    Background: Various antibiotic prophylaxis guidelines have been published such as the American Heart Association 2007, British Society for Antimicrobial Chemotherapy 2006, National Institute for Health and Clinical Excellence 2008, European Society of Cardiology 2015, and in Malaysia, the National Antibiotic Guideline 2014 and Clinical Practice Guidelines for the Prevention, Diagnosis and Management of Infective Endocarditis 2017. The aim of the study is to determine the pattern of antibiotic prophylaxis practice for dental procedure in children with congenital heart disease (CHD) at the Department of Paediatric Dentistry, Kuala Lumpur Hospital.

    Materials and Methods: A comparative cross-sectional study of dental records from 2010 to 2015 was done by collecting data on the source and reason of referral, types of heart condition, dental procedure, and antibiotic given.

    Results: There were 210 patients; 69.5% had acyanotic CHD, 21.9% cyanotic CHD, 6.7% repaired CHD with residual defects, and 1.9% with previous infective endocarditis. Slightly more than 58% were referred from government doctors (pediatric cardiologist and National Heart Institute). The common cause for referral was dental assessment (47.6%). Antibiotics were prescribed to 23.3% (49/210) patients, of which, 34.7% was given ampicillin or amoxicillin/clavulanic acid. About 96% of cyanotic heart cases undergoing invasive dental procedures were prescribed antibiotic prophylaxis. Almost 31% were prescribed with antibiotic prophylaxis even though it was not indicated.

    Conclusion: This study shows that there is variability in prescribing antibiotic prophylaxis, and it is important for dental clinicians to standardize the practice of giving antibiotic prophylaxis.

    Matched MeSH terms: Endocarditis, Bacterial*
  6. Mohd Nazrin Mohd Isa, Nor Azura Ahmad Tarmidzi, Norzalina Ghazali, Nalisha Mohamed Ramli, Ammar Yaseer Abdul Hakim@Abdul Khakin
    MyJurnal
    Antibiotic prophylaxis guidelines for infective endocarditis have been regularly
    revised and modified based on current scientific evidence. These guidelines commonly regarded as
    standard of care and determine the medicolegal standards. The aim of this study was to elicit the
    current practice of prophylaxis antibiotic for Infective endocarditis among general dental
    practitioner in Klang Valley. (Copied from article).
    Matched MeSH terms: Endocarditis, Bacterial
  7. Rajadurai J, Rajadurai P, Pasamanickam K
    Aust N Z J Med, 1993 Jun;23(3):311-2.
    PMID: 8352712
    Matched MeSH terms: Endocarditis, Bacterial/complications*
  8. Ho YH, Lim CT, Chua CZF, Chow HB, Chua HH, Fong AYY
    Med J Malaysia, 2023 Nov;78(6):743-750.
    PMID: 38031215
    INTRODUCTION: Despite recent advancements in the diagnosis and management of infective endocarditis (IE), it is associated with substantial morbidity and mortality. Our study objective is to determine the factors associated with in-hospital mortality in IE patients among the local population.

    MATERIALS AND METHODS: All IE patients who were diagnosed with definite or possible IE and were treated at Sarawak Heart Centre from 1st January 2020 to 31st December 2022 were recruited. We examined the demographic features of the subjects and the factors that contributed to in-hospital mortality. Multivariate logistic regression was used to analyse the associated factors and in-hospital mortality.

    RESULTS: Our study population comprised a total of 37 patients with a mean age of 46.4 years and male predominance. The in-hospital mortality rate of IE in this study was 44.4%. Haemodynamic instability and anaemia were found to be strong predictors of IE survival outcome, with an odds ratio of 51.5 and 35.7 respectively. Patients with vascular phenomenon and heart failure were at 10.5- and 6.0-times higher odds of dying, however, these two associations were found to be not statistically significant.

    CONCLUSION: The in-hospital mortality due to IE in our study was among the highest in developing countries. Factors of hypotension and optimal response to individual hemodynamic parameters may confer lower mortality. While anaemia is demonstrable as a risk factor for inpatient mortality, a target has yet to be reasonably established.

    Matched MeSH terms: Endocarditis, Bacterial*
  9. Jeyamalar R, Sivanesaratnam V
    Aust N Z J Obstet Gynaecol, 1991 May;31(2):123-4.
    PMID: 1930032
    Matched MeSH terms: Endocarditis, Bacterial/blood; Endocarditis, Bacterial/diagnosis; Endocarditis, Bacterial/drug therapy*
  10. Ngow HA, Wan Khairina WM
    J Infect Chemother, 2013 Feb;19(1):154-7.
    PMID: 22627887 DOI: 10.1007/s10156-012-0427-2
    Bacillus cereus endocarditis is rare. It has been implicated in immunocompromised individuals, especially in intravenous drug users as well as in those with a cardiac prosthesis. The patient was a 31-year-old ex-intravenous drug addict with a past history of staphylococcal pulmonary valve endocarditis, who presented with symptoms of decompensated cardiac failure. Echocardiography showed severe aortic regurgitation with an oscillating vegetation seen on the right coronary cusp of the aortic valve. The blood cultures grew Bacillus cereus. We report this as a rare case of Bacillus cereus endocarditis affecting a native aortic valve.
    Matched MeSH terms: Endocarditis, Bacterial/diagnosis*; Endocarditis, Bacterial/microbiology*; Endocarditis, Bacterial/pathology
  11. Andy Tang SO, Leong TS, Ruixin T, Chua HH, Chew LP
    Med J Malaysia, 2018 10;73(5):344-346.
    PMID: 30350823 MyJurnal
    Systemic Arcanobacterium pyogenes is a rare bacterial infection in humans.1The diagnosis of thrombotic thrombocytopenic purpura (TTP)-like syndrome and infective endocarditis (IE) is often elusive. We report a case of TTP-like syndrome associated with A. pyogenes endocarditis in a post-allogenic transplant patient.
    Matched MeSH terms: Endocarditis, Bacterial
  12. Pennie RA, Malik AS, Wilcox L
    J Clin Microbiol, 1996 May;34(5):1275-6.
    PMID: 8727917
    A 6-year-old boy presented to a university hospital in Malaysia with infective endocarditis complicating cyanotic congenital heart disease. Blood cultures showed a gram-positive, aerobic, coryneform-like bacillus identified by the hospital laboratory as Corynebacterium xerosis, but a reference laboratory identified the organism as a toxigenic strain of Corynebacterium diphtheriae. The two laboratories concurred on all biochemical test results except for sucrose fermentation.
    Matched MeSH terms: Endocarditis, Bacterial/complications; Endocarditis, Bacterial/diagnosis*; Endocarditis, Bacterial/microbiology*
  13. Malik AS
    Infection, 1995 9 1;23(5):306-8.
    PMID: 8557392
    Acinetobacter calcoaceticus, a gram-negative bacterium ubiquitous in soil, water and sewage, is a rare cause of endocarditis in children. The first case of Acinetobacter endocarditis in an infant is described. This patient had underlying tetralogy of Fallot with absent pulmonary valve. A review of the literature in English revealed only four other cases of Acinetobacter endocarditis in children; three of whom had underlying congenital heart disease. Like the other reported cases, this patient responded well to antibiotic treatment. Subsequently this patient underwent corrective cardiac surgery but died of post-operative complications.
    Matched MeSH terms: Endocarditis, Bacterial/drug therapy; Endocarditis, Bacterial/microbiology*
  14. Malik AS
    Ann Trop Paediatr, 1995 Sep;15(3):193-5.
    PMID: 8534036
    Haemophilus influenzae type b (Hib) endocarditis is a rare but potentially lethal condition. Only ten cases have been reported in the English literature. This report describes an 8-month-old Malay child with a ventricular septal defect who developed Hib endocarditis and died after 4 weeks of hospitalization. The literature is reviewed and previously reported cases summarized.
    Matched MeSH terms: Endocarditis, Bacterial/diagnosis*; Endocarditis, Bacterial/drug therapy
  15. Ong ML
    Br Heart J, 1993 Sep;70(3):276-7; discussion 277-8.
    PMID: 8398501
    A 17 year old girl with a congenital right coronary artery to coronary sinus fistula presented with recurrent septic pulmonary embolism secondary to tricuspid valve endocarditis. The diagnosis was made on the basis of echocardiography and cardiac angiography.
    Matched MeSH terms: Endocarditis, Bacterial/complications*; Endocarditis, Bacterial/ultrasonography
  16. Tan YA, Ng KC, Cheo SW, Low QJ, Chia YK
    QJM, 2020 07 01;113(7):485-487.
    PMID: 32053172 DOI: 10.1093/qjmed/hcaa025
    Matched MeSH terms: Endocarditis, Bacterial/diagnosis*; Endocarditis, Bacterial/microbiology
  17. Pairan MS, Mohammad N, Abdul Halim S, Wan Ghazali WS
    BMJ Case Rep, 2018 Sep 10;2018.
    PMID: 30206067 DOI: 10.1136/bcr-2018-225265
    We present an interesting case of late-onset intracranial bleeding (ICB) as a complication of Streptococcus gordonii causing infective endocarditis. A previously healthy young woman was diagnosed with infective endocarditis. While she was already on treatment for 2 weeks, she had developed seizures with a localising neurological sign. An urgent non-contrasted CT brain showed massive left frontoparietal intraparenchymal bleeding. Although CT angiogram showed no evidence of active bleeding or contrast blush, massive ICB secondary to vascular complication of infective endocarditis was very likely. An urgent decompressive craniectomy with clot evacuation was done immediately to release the mass effect. She completed total 6 weeks of antibiotics and had postoperative uneventful hospital stay despite having a permanent global aphasia as a sequel of the ICB.
    Matched MeSH terms: Endocarditis, Bacterial/complications*; Endocarditis, Bacterial/drug therapy
  18. Khoo PLZ, Poon JS, Tan GJS, Yahya A, Chan KMJ
    Med J Malaysia, 2020 11;75(6):722-730.
    PMID: 33219184
    INTRODUCTION: Heart valve disease comprises a cluster of conditions affecting the aortic, mitral, pulmonary and tricuspid valves. This paper reviews all the research on heart valve disease in Malaysia published between the years 2000- 2016.

    METHODS: The methodology was based on the search process described in the paper, "Bibliography of clinical research in Malaysia: methods and brief results". The search databases included PubMed, Scopus and several Malaysian journals such as MyJurnal and UKM Journal Repository, by using the following keywords: (heart valve disease OR infective endocarditis OR rheumatic heart disease) and (Malaysia).

    RESULTS: In all 94 papers were identified of which 39 papers were selected and reviewed on the basis of their relevance. The local studies contributed to the knowledge and understanding of the epidemiology, aetiology, pathophysiology, clinical presentations, investigations, treatment, and outcomes of heart valve disease in the country.

    DISCUSSION: The clinical relevance of the studies performed in the country is discussed along with recommendations for future research.

    Matched MeSH terms: Endocarditis, Bacterial
  19. Loong YY, Fadzli A, Lim PH, Rakhi G
    We describe a patient who had fever and bilateral cortical blindness and was later found to have leaking intracerebral mycotic aneurysm secondary to Staphylococcus aureus endocarditis. He had a vegetation at the .tricuspid valve with evidence of systemic embolisation, however, chest radiograph did not reveal any evidence of pulmonary emboli.
    Keywords: Endocarditis, cortical blindness, mycotic aneurysm, Staphylococcus
    Matched MeSH terms: Endocarditis, Bacterial
  20. Yew KL, Razali F
    Acute Card Care, 2015;17(2):32.
    PMID: 26458028 DOI: 10.3109/17482941.2015.1066822
    Matched MeSH terms: Endocarditis, Bacterial/pathology*
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