Displaying publications 1 - 20 of 22 in total

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  1. Kah TA, Annuar FH
    N Engl J Med, 2012 Jul 19;367(3):258.
    PMID: 22808961 DOI: 10.1056/NEJMicm1112964
    Matched MeSH terms: Eye Neoplasms/diagnosis*; Eye Neoplasms/radiography
  2. Sukumaran DO
    Med J Malaysia, 1991 Jun;46(2):129-35.
    PMID: 1839416
    Retinoblastoma was clinically diagnosed in 38 patients in the University Hospital between 1968 to 1988. White pupil or cat's eye reflex, found in 25 patients, was the most common symptom. Four patients refused any form of treatment. Of the 27 histopathologically confirmed cases, 16 were males and 11 were females. There was no ethnic group predominance, although a male preponderance was observed among Malay patients (M:F 3:1, p less than 0.05). Treatment in cases with unilateral disease, without extra ocular extension consisted of enucleation of the involved eye, with close examination of the contralateral eye in follow-up. In cases presenting with bilateral tumour the worse eye was removed. Of 20 cases of histopathologically proven unilateral retinoblastoma treated surgically, 12 patients survived for a mean period of 4.5 years (Range: 1-19 years). The defaulter rate for this group of patients was 55%. None of the 7 cases of bilateral retinoblastoma survived beyond 5 years (Mean survival 2.5 years).
    Matched MeSH terms: Eye Neoplasms/diagnosis*; Eye Neoplasms/surgery
  3. Lau LL, Lung CK, Ahmad SS
    Indian J Ophthalmol, 2015 Nov;63(11):856-8.
    PMID: 26669339 DOI: 10.4103/0301-4738.171969
    A 34-year-old patient with a swelling over the upper eyelid for nearly 1 year was seen in our clinic. The history, examination and investigations were suggestive of a benign lacrimal gland tumor. The tumor and lacrimal gland were resected. Subsequent histopathological examination revealed the tumor was a primary ductal adenocarcinoma of the lacrimal gland. This is a very rare tumor with less than half a dozen cases reported so far. This case report is being presented to highlight an unusual presentation of this rare malignancy.
    Matched MeSH terms: Eye Neoplasms
  4. Soong T, Soong V, Salvi SM, Raynor M, Mudhar H, Goel S, et al.
    Cornea, 2008 Dec;27(10):1186-8.
    PMID: 19034139 DOI: 10.1097/ICO.0b013e31817a5d0b
    Primary corneal myxoma is extremely rare. It has only been reported on 2 previous occasions. Secondary corneal myxomas are more common, arising from corneal diseases such as infective keratitis, keratoconus, and bullous keratopathy. Myxomas occur commonly in other soft tissues such as the heart, paranasal sinuses, and muscles but can rarely present in periocular structures including the conjunctiva, orbit, and eyelid. Ours is only the third case of primary corneal myxoma reported in the literature and illustrates several unusual features. These include an inferonasal location between the corneal epithelium and Bowman layer and with no relationship to the corneal stroma, rapid tumor growth over a 3-month period, and no previous ocular trauma or conjunctival pathology. The histology of this lesion has an important part to play in the management of this condition as it determines the cellular origin, establishes a benign or malignant state, and helps with treatment and prognosis. One reported case of primary corneal myxoma recurred within 2 months after local resection. This was treated with bandage soft contact lens, and no recurrence had been reported since. Our case is now 12 months post op and has had no recurrence.
    Matched MeSH terms: Eye Neoplasms/pathology*; Eye Neoplasms/surgery*; Eye Neoplasms/ultrasonography
  5. Wahab NA, Ramasamy U, George J, Madhavan M, Arif AR, Abdullah J
    Med J Malaysia, 2006 Dec;61(5):641-3.
    PMID: 17623971 MyJurnal
    We report a case of an adult who presented with progressive swelling in the right eye with suggestive of intracranial lesion on imaging. Histopathological revealed a lacrimal gland malignant mixed tumour.
    Matched MeSH terms: Eye Neoplasms/diagnosis; Eye Neoplasms/pathology; Eye Neoplasms/surgery*
  6. Hisham RB, Thuaibah H, Gul YA
    Asian J Surg, 2006 Apr;29(2):95-7.
    PMID: 16644510
    We present the case of a 32-year-old woman who, 10 months after abdominoperineal resection and total mesorectal excision for a locally advanced mucinous adenocarcinoma of the rectum, presented with local recurrence and metastases to the breast, spine, the left eye and orbit. Following surgery, due to the patient's personal reasons, adjuvant chemoradiation was not given. The patient died 2 months later, with disseminated cancer. To the best of our knowledge, breast as well as ocular metastasis in a patient with mucinous adenocarcinoma of the rectum has never been reported and, therefore, needs to be documented.
    Matched MeSH terms: Eye Neoplasms/secondary*
  7. Vickers PG, Shue CL, Ahmad H
    Med J Malaysia, 1999 Jun;54(2):277-9.
    PMID: 10972044
    Naso-lacrimal duct tumours are uncommon and present with epiphora and swelling. Since the naso-lacrimal duct is embedded in bone for the majority of its anatomical length, the late presentation of proptosis is due to orbital extension of the tumour. Radical surgical treatment is necessary to establish clear margins and facilitate reconstruction.
    Matched MeSH terms: Eye Neoplasms/surgery*
  8. Sivanesan S, Chandran S
    Med J Malaysia, 1982 Sep;37(3):257-60.
    PMID: 6294490
    Three consecutive cases of lacrimal gland carcinoma seen at the University Hospital during a twelve-year period are presented. One case was unusual, presenting at the age of sixteen years and developing metastases to the lungs. Adenoid cystic carcinoma is the commonest type of lacrimal malignancy and its clinico-pathological features and surgical management are discussed.
    Matched MeSH terms: Eye Neoplasms/pathology*
  9. Fong HC, Vijendran M, Chandran S, Ng KK
    Med J Malaysia, 1976 Jun;30(4):299-303.
    PMID: 979732
    Matched MeSH terms: Eye Neoplasms*
  10. Maharajah KR, Hussein A, Mohamad H, Khan SA, At LS
    Orbit, 2009;28(5):306-8.
    PMID: 19874126 DOI: 10.3109/01676830903044346
    We report a case of primary non-Hodgkins lymphoma of the lacrimal sac in a 60-year-old Asian lady, who presented with persistent epiphora and recurrent medial canthal swelling. Primary lymphoma of the lacrimal sac is rare and it can be easily misdiagnosed. Delayed in diagnosis may be related to mortality. To minimize the risk of overlooking specific pathology it is important to assess the appearance of the lacrimal sac and its surrounding structures intraoperatively. Biopsy of the lacrimal sac is required in cases where specific pathology is suspected.
    Matched MeSH terms: Eye Neoplasms/complications; Eye Neoplasms/diagnosis*; Eye Neoplasms/therapy
  11. Reddy SC, Das PK
    Malays J Pathol, 1996 Dec;18(2):113-20.
    PMID: 10879232
    A total of 89 histopathologically proven ocular tumours and tumour-like lesions treated in Hospital University Sains Malaysia, Kubang Kerian, Kelantan over a period of nine years were reviewed for their age distribution, site of lesion and histological type. The tumours were observed in all age groups with a maximum prevalence in the first decade. Twenty lesions were malignant and 69 were benign. The eyelid was the most frequent location (51%), followed by the conjunctiva (32%). Retinoblastoma was the most common malignant tumour (10 cases) and dermoid cyst was the most common tumour-like lesion (16 cases).
    Matched MeSH terms: Eye Neoplasms/epidemiology*; Eye Neoplasms/pathology; Eye Neoplasms/surgery
  12. Ramlee N, Ramli N, Tajudin LS
    Orbit, 2007 Jun;26(2):137-9.
    PMID: 17613864
    We reported a case of pleomorphic adenoma of the lacrimal gland involving the palpebral lobe in young teenage girl of Asian origin. The presentation at young age group is rare, which initially misdiagnosed as a large chalazion. The benign tumor with its intact pseudocapsule was removed through lateral orbitotomy together with the suspicious looking orbital lobe.
    Matched MeSH terms: Eye Neoplasms/diagnosis*; Eye Neoplasms/surgery
  13. Sinniah D, Narasimha G, Prathap K
    Acta Ophthalmol, 1980 Oct;58(5):819-24.
    PMID: 7211270
    Twenty children with retinoblastoma are reviewed who were treated at the University Hospital, Kuala Lumpur over a 10-year-period. They constitute 6.6% of childhood malignancies and without exception all presented with advanced disease. Hereditary cases were notably absent in the the series probably because past cases have almost invariably succumbed without an opportunity to transmit the gene. With enucleation and radiotherapy six of the patients have survived from 2 to 12 years. The addition of vincristine and cyclophosphamide has not been associated with improved survival.
    Matched MeSH terms: Eye Neoplasms/epidemiology*; Eye Neoplasms/therapy
  14. Reddy SC, Madhavan M, Mutum SS
    Ophthalmologica, 2000 Sep-Oct;214(5):368-72.
    PMID: 10965254 DOI: 10.1159/000027523
    Breast carcinoma is the most common primary tumor producing intraocular metastasis. Metastases to the iris and ciliary body are relatively rare. The authors report a case of a 61-year-old lady, operated for carcinoma of the left breast 3 years back, who presented with symptoms and signs of acute narrow-angle glaucoma in the right eye. A diffuse whitish plaque-like mass in the upper nasal quadrant of the iris with an episcleral nodule on the limbus in the corresponding area and all the signs of acute narrow-angle glaucoma were present in the right eye. Intraocular pressure was controlled medically. Fine-needle aspiration cytology from the episcleral nodule showed malignant cells. Histopathology of the excised nodule showed metastatic poorly differentiated carcinoma, and the cellular pattern was similar to the carcinoma of the breast. There was no other metastasis anywhere in the body. Fine-needle aspiration cytology from an external lesion of the eye is a less invasive and easier procedure than paracentesis to diagnose the metastatic nature of the lesions. The rare features in our case are the clinical presentation as acute glaucoma and the ocular structures being the first and only site of metastasis.
    Matched MeSH terms: Eye Neoplasms/complications; Eye Neoplasms/pathology; Eye Neoplasms/secondary; Eye Neoplasms/therapy
  15. Tang IP, Periyannan P, Prepageran N, Shashinder S, Singh A, Bhagubhai PN
    Eur J Cancer Care (Engl), 2011 Jan;20(1):93-5.
    PMID: 20088917 DOI: 10.1111/j.1365-2354.2009.01147.x
    We report a very rare case of recurrent nasopharyngeal carcinoma with local involvement of lacrimal sac. The patient was treated with chemotherapy and there was no recurrence noted after 1 year of follow-up.
    Matched MeSH terms: Eye Neoplasms/pathology*; Eye Neoplasms/therapy
  16. Tengku-Fatishah A, Abdullah B, Sanjeevan N, Nurul-Shuhada AH, Sharifah-Emilia TS, Haron J, et al.
    Can J Ophthalmol, 2019 08;54(4):e196-e199.
    PMID: 31358169 DOI: 10.1016/j.jcjo.2018.10.006
    Matched MeSH terms: Eye Neoplasms/diagnosis*; Eye Neoplasms/surgery
  17. Abdulhadi LM
    Chin J Dent Res, 2010;13(1):61-6.
    PMID: 20936194
    A 70-year-old man who suffered from extensive extra and intraoral defects was rehabilitated with a prosthesis using multiple retaining means. The treatment was performed in two parts: externally involving the construction of an episthesis supported only by the remaining intact boundaries of the defect and retained by mini-dental implants and spectacle frame with a modified ear hook; and intraorally by an acrylic resin obturator to restore the function of the hemi-sectioned hard and soft palate. The episthesis was securely retained with minimal movement and/or dislodgment of the prosthesis during function. Multiple retentive techniques may be used to fix heavy external prostheses as an alternative to conventional implants or biological adhesives.
    Matched MeSH terms: Eye Neoplasms/rehabilitation
  18. Chandran S
    Singapore Med J, 1973 Dec;14(4):497-500.
    PMID: 4788120
    The primary cause of 68 enucleations in the University Hospital, Kuala Lumpur, are reviewed and compared with those from Uganda and Jerusalem. Trauma 25% especially in the 20 - 29 age group was the most important cause, followed by corneal diseases 22% seen largely over the age of 50. Malignant tumours 16% consisting nearly all of retinoblastoma and a very low incidence of malignant melanoma when compared with the Caucasians. Glaucoma 12% was mainly of the narrow angle type. Males predominate nearly all age groups with an overall ratio of 2:1 and a peak of 5:1 in trauma.
    Matched MeSH terms: Eye Neoplasms/surgery*
  19. Farrah-Hani Imran, Muthukumaran, Guhan, Enda, Kelly, Jegan Thanabalan, Farizal Fadzil, Faridah Hanum
    MyJurnal
    This was a case of a young lady presenting with 10 year history of a mass in the right eye. It was found to be an adenocarcinoma of the lacrimal gland from histopathological biopsy. She underwent wide excision, orbital exenteration and reconstruction with a free rectus abdominis flap. Unfortunately, she had a tumour recurrence which was not controlled by radiotherapy and a second excision. The behavior of the tumour was aggressive, resulting in widespread metastases. She passed away within a year of her presentation. Of note, the histopathology report from the second excision turned out to be sarcomatoid carcinoma. This is described in the literature as dedifferentiation, or high grade transformation (HGT). Occurrence of dedifferentiation in salivary gland tumours is well-established, but not as well-described in lacrimal gland tumours. In this case, there was a severely delayed presentation of a lacrimal gland adenocarcinoma in a young person, which underwent dedifferentiation into a sarcomatoid carcinoma. This phenomena is associated with aggressive tumour biology behavior and poor prognosis, despite surgery and radiotherapy.
    Matched MeSH terms: Eye Neoplasms
  20. Sherazi ZA, Jayakumar CR
    Singapore Med J, 1992 Oct;33(5):496-9.
    PMID: 1455277
    To assess the importance of Computed Tomography(CT) in the evaluation of retinoblastoma, we reviewed thirteen cases of retinoblastoma which presented at Hospital University Sains Malaysia, Kelantan, Malaysia, from August 1986 to June 1991. High resolution computed tomography of the orbits was performed in all patients prior to therapy. Nine patients (69%) had unilateral and four (31%) had bilateral retinoblastoma. The interesting features were the remarkably high incidence in the right eye (89%) as compared to the left eye (11%) in unilateral retinoblastoma, and overall predominance of the male population (male to female ratio was 2:1). Computed tomography detected intraocular calcification in 82% of the tumourous eyes. All patients presented at late stages when tumours were of large size. The presence of calcification was not related to the size of the tumour. CT detected calcification in a suspected retinoblastoma with a high degree of accuracy. Computed tomographic evidence of intraocular calcification in children under 3 years of age is highly suggestive of retinoblastoma.
    Matched MeSH terms: Eye Neoplasms/radiography*
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