Displaying publications 1 - 20 of 145 in total

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  1. Antu UB, Roy TK, Roshid MM, Mitu PR, Barman MK, Tazry J, et al.
    Int J Biol Macromol, 2025 Apr;303:140570.
    PMID: 39904432 DOI: 10.1016/j.ijbiomac.2025.140570
    Nanocellulose, a promising green material derived from various bio-sources, has potentiality on and off-site in the agricultural sector. Due to its special qualities, which include high strength, hydrophilicity, and biocompatibility, it is a material that may be used in a variety of industries, especially agriculture. This review explores in this article production processes, post-processing procedures, and uses of nanocellulose in soil fertility increment and sustainable agriculture. A variety of plant materials, agricultural waste, and even microbes can be used to isolate nanocellulose. Nanocellulose is produced using both top-down and bottom-up methods, each of which has benefits and limitations of its own. It can be applied as nano-biofertilizer in agriculture to enhance beneficial microbial activity, increase nutrient availability, and improve soil health. Moreover, nanocellulose can be used in fertilizer and pesticide formulations with controlled releases to increase efficacy and lessen environmental effects. Innovative approaches to sustainable agriculture are provided by nanocellulose technologies, which also support the UN's Sustainable Development Goals (SDGs), especially those pertaining to eradicating hunger and encouraging responsible consumption. Nanocellulose promotes climate action and ecosystem preservation by increasing resource efficiency and decreasing dependency on hazardous chemicals, ultimately leading to the development of a circular bioeconomy. Nonetheless, there are still issues with the high cost of production and the energy-intensive isolation procedures. Despite its various potentialities, challenges such as high production costs, environmental concerns, and regulatory issues must be addressed for nanocellulose to be widely adopted and effectively integrated into farming practices.
    Matched MeSH terms: Nanostructures/chemistry
  2. Yaghoubi A, Mélinon P
    Sci Rep, 2013;3:1083.
    PMID: 23330064 DOI: 10.1038/srep01083
    In recent years, plasma-assisted synthesis has been extensively used in large scale production of functional nano- and micro-scale materials for numerous applications in optoelectronics, photonics, plasmonics, magnetism and drug delivery, however systematic formation of these minuscule structures has remained a challenge. Here we demonstrate a new method to closely manipulate mesostructures in terms of size, composition and morphology by controlling permeability at the boundaries of an impermeable plasma surrounded by a blanket of neutrals. In situ and rapid growth of thin films in the core region due to ion screening is among other benefits of our method. Similarly we can take advantage of exceptional properties of plasma to control the morphology of the as deposited nanostructures. Probing the plasma at boundaries by means of observing the nanostructures, further provides interesting insights into the behaviour of gas-insulated plasmas with possible implications on efficacy of viscous heating and non-magnetic confinement.
    Matched MeSH terms: Nanostructures/chemistry*
  3. Zhen Y, Peng C, Gao H, Bai L, Song Y, Gao P, et al.
    Biomacromolecules, 2024 Dec 09;25(12):7767-7776.
    PMID: 39526987 DOI: 10.1021/acs.biomac.4c01082
    This study found that the sources of cellulose have a significant effect on the parameters related to the kinks present in nanocellulose. During nanocellulose preparation, 2,2,6,6-tetramethylpiperidinyl-1-oxyl (TEMPO)-mediated oxidation induced partial depolymerization on whole cellulose and made the amorphous regions more susceptible to consequent mechanical treatment irrespective of cellulose sources. However, plant cellulose microfibrils were prone to break into shorter nanocellulose with fewer kinks, while bacterial and tunicate cellulose were more likely to bend rather than break, thus leading to the generation of more kinks. The kinks did not show significant effects on the size, crystallinity index, and thermal properties of nanocellulose for each cellulose source, though the kink numbers were positively related to the mechanical performance of nanocellulose. Collectively, this study elucidated the kink formation mechanisms and clarified the effects of kinks on nanocellulose performance, thus providing new insights into understanding the source and behaviors of microdefects present in nanocellulose.
    Matched MeSH terms: Nanostructures/chemistry
  4. Yusuf J, Firdaus AHM, Sapuan SM, Rashid U, Ilyas RA, Hassan MR, et al.
    Int J Biol Macromol, 2024 Dec;282(Pt 5):137244.
    PMID: 39505165 DOI: 10.1016/j.ijbiomac.2024.137244
    Nanocellulose-graphene hybrid composites for high-performance uses have been the focus of recent research. In contrast to graphene, which has great conductivity and mechanical strength, nanocellulose possesses special qualities like renewability and biocompatibility but lacks electrical conductivity. Since graphene-nanocellulose has such promising features, efforts to make flexible electronic composites employing them have accelerated. However, the environmental impacts are needed to be addressed prior to the applications of these hybrid composites. This review article explores environmental aspects for nanocellulose-graphene hybrid composites because of their sustainability, which is a major step in the right direction. The article also emphasizes how these composites have the potential to transform several industries and open the door to a more environmentally friendly future. This paper explores into the most recent developments in nanocellulose-graphene hybrid composites, highlighting its environmental benefits and adaptability. These composites offer remarkable performance by combining the strength and conductivity of graphene with the mechanical, electrical, and thermal capabilities of nanocellulose.
    Matched MeSH terms: Nanostructures/chemistry
  5. Ahmed S, Islam MS, Antu UB, Islam MM, Rajput VD, Mahiddin NA, et al.
    Int J Biol Macromol, 2025 Jan;285:137979.
    PMID: 39592042 DOI: 10.1016/j.ijbiomac.2024.137979
    Nanocellulose, obtained from natural cellulose, has attracted considerable interest for its distinctive properties and wide-ranging potential applications. Studies suggest that nanocellulose improves the thermal, mechanical, and barrier properties of conventional cellulose. This review investigates the production, properties, approach, and application of nanocellulose from various sources in agriculture. The main role play of cellulose-nanocomposite is discussed as a seed coating agent to improve seed dispersal, germination, protection against fungi and insects, plant growth promoter, adsorption of targeted pollutants, providing water and nutrient retention, and other advantages. As a nobility, we included all mechanical, chemical, and static culture approaches to the production procedure of nanocellulose and its application as a nanocarrier in soil, including the unique properties of nanocellulose, such as its high surface area, inherent hydrophilicity, and ease of surface modification. Here, methods such as melt compounding, solution casting, and in situ polymerization were evaluated to incorporate nanoparticles into cellulose materials and produce nanocellulose and cellulose-nanocomposites with improved strength, stability, water resistance, and reduced gas permeability. The commercialization faces challenges such as high production costs, scalability issues, and the need for more research on environmental impacts and plant interactions. Despite these hurdles, this field is promising, with ongoing advancements likely to yield new and improved agricultural materials. This review thoroughly examines the innovative application of nanocellulose in slow and controlled-release fertilizers and pesticides, to transform nutrient management, boost crop productivity, and minimize the environmental impact.
    Matched MeSH terms: Nanostructures/chemistry
  6. Chutturi M, Kelkar BU, Yadav SM, Wibowo ES, Bhuyar P, Naik BP, et al.
    Int J Biol Macromol, 2025 Apr;304(Pt 2):140881.
    PMID: 39947566 DOI: 10.1016/j.ijbiomac.2025.140881
    Nanolignin is a biomacromolecule nanomaterial obtained from lignin, a natural plant polymer. It has attracted considerable attention as a potential nanofiller for polymer composites owing to its remarkable properties, such as biodegradability, antioxidant activity, and high specific surface area. However, the development of biological macromolecule nano lignin-based polymer composites faces several challenges, mainly due to the complex structure and poor chemical compatibility of lignin with most polymers. A comprehensive summary of the functionalization strategies and synthesis techniques for nanolignin is provided in this article. The morphological, structural, and thermal characterization of nanolignin is also reviewed. Furthermore, this review summarizes the recent progress of nanolignin and its composites prepared using various polymers, such as polyvinyl alcohol, poly (methyl methacrylate), polylactic acid, phenol formaldehyde, and natural rubber. This study concludes by outlining the possible uses of nanolignin-reinforced polymer composites and the potential opportunities and disadvantages of using nanolignin as a reinforcement in polymer composites for several value-added applications.
    Matched MeSH terms: Nanostructures/chemistry
  7. Karimi S, Tahir PM, Karimi A, Dufresne A, Abdulkhani A
    Carbohydr Polym, 2014 Jan 30;101:878-85.
    PMID: 24299851 DOI: 10.1016/j.carbpol.2013.09.106
    Cellulosic fibers from kenaf bast were isolated in three distinct stages. Initially raw kenaf bast fibers were subjected to an alkali pulping process. Then pulped fibers undergone a bleaching process and finally both pulped and bleached fibers were separated into their constituent nanoscale cellulosic fibers by mechanical shearing. The influence of each treatment on the chemical composition of fibers was investigated. Moreover morphology, functional groups, crystallinity, and thermal behavior of fiber hierarchy at different stages of purification were studied using scanning and transmission electron microscopies, Fourier transform infrared spectroscopy (FTIR), X-ray diffraction (XRD) and thermogravimetric analysis (TGA), respectively. Microscopy studies revealed that applied procedures successfully isolated nanoscale cellulosic fibers from both unbleached and bleached pulps. Chemical composition analysis and FTIR spectroscopy showed that lignin and hemicellulose were almost entirely removed by the applied treatments. XRD and TGA analyses demonstrated progressive enhancement of properties in fibers, hierarchically, in going from micro to nano scale. Interestingly no significant evolution was observed between obtained data of characterized ubnleached and bleached nanofibers.
    Matched MeSH terms: Nanostructures/chemistry*
  8. Ngo TA, Dinh H, Nguyen TM, Liew FF, Nakata E, Morii T
    Chem Commun (Camb), 2019 Oct 15;55(83):12428-12446.
    PMID: 31576822 DOI: 10.1039/c9cc04661e
    DNA is an attractive molecular building block to construct nanoscale structures for a variety of applications. In addition to their structure and function, modification the DNA nanostructures by other molecules opens almost unlimited possibilities for producing functional DNA-based architectures. Among the molecules to functionalize DNA nanostructures, proteins are one of the most attractive candidates due to their vast functional variations. DNA nanostructures loaded with various types of proteins hold promise for applications in the life and material sciences. When loading proteins of interest on DNA nanostructures, the nanostructures by themselves act as scaffolds to specifically control the location and number of protein molecules. The methods to arrange proteins of interest on DNA scaffolds at high yields while retaining their activity are still the most demanding task in constructing usable protein-modified DNA nanostructures. Here, we provide an overview of the existing methods applied for assembling proteins of interest on DNA scaffolds. The assembling methods were categorized into two main classes, noncovalent and covalent conjugation, with both showing pros and cons. The recent advance of DNA-binding adaptor mediated assembly of proteins on the DNA scaffolds is highlighted and discussed in connection with the future perspectives of protein assembled DNA nanoarchitectures.
    Matched MeSH terms: Nanostructures/chemistry
  9. Khalid K, Tan X, Mohd Zaid HF, Tao Y, Lye Chew C, Chu DT, et al.
    Bioengineered, 2020 12;11(1):328-355.
    PMID: 32138595 DOI: 10.1080/21655979.2020.1736240
    With the unique properties such as high surface area to volume ratio, stability, inertness, ease of functionalization, as well as novel optical, electrical, and magnetic behaviors, nanomaterials have a wide range of applications in various fields with the common types including nanotubes, dendrimers, quantum dots, and fullerenes. With the aim of providing useful insights to help future development of efficient and commercially viable technology for large-scale production, this review focused on the science and applications of inorganic and organic nanomaterials, emphasizing on their synthesis, processing, characterization, and applications on different fields. The applications of nanomaterials on imaging, cell and gene delivery, biosensor, cancer treatment, therapy, and others were discussed in depth. Last but not least, the future prospects and challenges in nanoscience and nanotechnology were also explored.
    Matched MeSH terms: Nanostructures/chemistry*
  10. Bakhsheshi-Rad HR, Hamzah E, Kasiri-Asgarani M, Jabbarzare S, Iqbal N, Abdul Kadir MR
    Mater Sci Eng C Mater Biol Appl, 2016 Mar;60:526-537.
    PMID: 26706560 DOI: 10.1016/j.msec.2015.11.057
    The present study addressed the synthesis of a bi-layered nanostructured fluorine-doped hydroxyapatite (nFHA)/polycaprolactone (PCL) coating on Mg-2Zn-3Ce alloy via a combination of electrodeposition (ED) and dip-coating methods. The nFHA/PCL composite coating is composed of a thick (70-80 μm) and porous layer of PCL that uniformly covered the thin nFHA film (8-10 μm) with nanoneedle-like microstructure and crystallite size of around 70-90 nm. Electrochemical measurements showed that the nFHA/PCL composite coating presented a high corrosion resistance (R(p)=2.9×10(3) kΩ cm(2)) and provided sufficient protection for a Mg substrate against galvanic corrosion. The mechanical integrity of the nFHA/PCL composite coatings immersed in SBF for 10 days showed higher compressive strength (34% higher) compared with the uncoated samples, indicating that composite coatings can delay the loss of compressive strength of the Mg alloy. The nFHA/PCL coating indicted better bonding strength (6.9 MPa) compared to PCL coating (2.2 MPa). Immersion tests showed that nFHA/PCL composite-coated alloy experienced much milder corrosion attack and more nucleation sites for apatite compared with the PCL coated and uncoated samples. The bi-layered nFHA/PCL coating can be a good alternative method for the control of corrosion degradation of biodegradable Mg alloy for implant applications.
    Matched MeSH terms: Nanostructures/chemistry*
  11. Danial WH, Abdul Majid Z, Mohd Muhid MN, Triwahyono S, Bakar MB, Ramli Z
    Carbohydr Polym, 2015 Mar 15;118:165-9.
    PMID: 25542122 DOI: 10.1016/j.carbpol.2014.10.072
    The study reports on the preparation of cellulose nanocrystals (CNCs) from wastepaper, as an environmental friendly approach of source material, which can be a high availability and low-cost precursor for cellulose nanomaterial processing. Alkali and bleaching treatments were employed for the extraction of cellulose particles followed by controlled-conditions of acid hydrolysis for the isolation of CNCs. Attenuated total reflectance Fourier Transform Infrared (ATR FTIR) spectroscopy was used to analyze the cellulose particles extracted while Transmission electron microscopy images confirmed the presence of CNCs. The diameters of CNCs are in the range of 3-10nm with a length of 100-300nm while a crystallinity index of 75.9% was determined from X-ray diffraction analysis. The synthesis of this high aspect ratio of CNCs paves the way toward alternative reuse of wastepaper in the production of CNCs.
    Matched MeSH terms: Nanostructures/chemistry*
  12. Qi H, Huang G, Han Y, Zhang X, Li Y, Pingguan-Murphy B, et al.
    Tissue Eng Part B Rev, 2015 Jun;21(3):288-97.
    PMID: 25547514 DOI: 10.1089/ten.TEB.2014.0494
    Deoxyribonucleic acid (DNA) emerges as building bricks for the fabrication of nanostructure with complete artificial architecture and geometry. The amazing ability of DNA in building two- and three-dimensional structures raises the possibility of developing smart nanomachines with versatile controllability for various applications. Here, we overviewed the recent progresses in engineering DNA machines for specific bioengineering and biomedical applications.
    Matched MeSH terms: Nanostructures/chemistry*
  13. Zhu T, Chong MN, Chan ES
    ChemSusChem, 2014 Nov;7(11):2974-97.
    PMID: 25274424 DOI: 10.1002/cssc.201402089
    The recent developments of nanostructured WO3 thin films synthesized through the electrochemical route of electrochemical anodization and cathodic electrodeposition for the application in photoelectrochemical (PEC) water splitting are reviewed. The key fundamental reaction mechanisms of electrochemical anodization and cathodic electrodeposition methods for synthesizing nanostructured WO3 thin films are explained. In addition, the effects of metal oxide precursors, electrode substrates, applied potentials and current densities, and annealing temperatures on size, composition, and thickness of the electrochemically synthesized nanostructured WO3 thin films are elucidated in detail. Finally, a summary is given for the general evaluation practices used to calculate the energy conversion efficiency of nanostructured WO3 thin films and a recommendation is provided to standardize the presentation of research results in the field to allow for easy comparison of reported PEC efficiencies in the near future.
    Matched MeSH terms: Nanostructures/chemistry*
  14. H P S AK, Saurabh CK, A S A, Nurul Fazita MR, Syakir MI, Davoudpour Y, et al.
    Carbohydr Polym, 2016 Oct 05;150:216-26.
    PMID: 27312632 DOI: 10.1016/j.carbpol.2016.05.028
    Chitin is one of the most abundant natural polymers in world and it is used for the production of chitosan by deacetylation. Chitosan is antibacterial in nature, non-toxic, and biodegradable thus it can be used for the production of biodegradable film which is a green alternative to commercially available synthetic counterparts. However, their poor mechanical and thermal properties restricted its wide spread applications. Chitosan is highly compatible with other biopolymers thus its blending with cellulose and/or incorporation of nanofiber isolated from cellulose namely cellulose nanofiber and cellulose nanowhiskers are generally useful. Cellulosic fibers in nano scale are attractive reinforcement in chitosan to produce environmental friendly composite films with improved physical properties. Thus chitosan based composites have wide applicability and potential in the field of biomedical, packaging and water treatment. This review summarises properties and preparation procedure of chitosan-cellulose blends and nano size cellulose reinforcement in chitosan bionanocomposites for different applications.
    Matched MeSH terms: Nanostructures/chemistry*
  15. Ong HS, Rahim MS, Firdaus-Raih M, Ramlan EI
    PLoS One, 2015;10(8):e0134520.
    PMID: 26258940 DOI: 10.1371/journal.pone.0134520
    The unique programmability of nucleic acids offers alternative in constructing excitable and functional nanostructures. This work introduces an autonomous protocol to construct DNA Tetris shapes (L-Shape, B-Shape, T-Shape and I-Shape) using modular DNA blocks. The protocol exploits the rich number of sequence combinations available from the nucleic acid alphabets, thus allowing for diversity to be applied in designing various DNA nanostructures. Instead of a deterministic set of sequences corresponding to a particular design, the protocol promotes a large pool of DNA shapes that can assemble to conform to any desired structures. By utilising evolutionary programming in the design stage, DNA blocks are subjected to processes such as sequence insertion, deletion and base shifting in order to enrich the diversity of the resulting shapes based on a set of cascading filters. The optimisation algorithm allows mutation to be exerted indefinitely on the candidate sequences until these sequences complied with all the four fitness criteria. Generated candidates from the protocol are in agreement with the filter cascades and thermodynamic simulation. Further validation using gel electrophoresis indicated the formation of the designed shapes. Thus, supporting the plausibility of constructing DNA nanostructures in a more hierarchical, modular, and interchangeable manner.
    Matched MeSH terms: Nanostructures/chemistry*
  16. Chen YW, Lee HV, Juan JC, Phang SM
    Carbohydr Polym, 2016 Oct 20;151:1210-1219.
    PMID: 27474672 DOI: 10.1016/j.carbpol.2016.06.083
    Nanocellulose was successfully isolated from Gelidium elegans red algae marine biomass. The red algae fiber was treated in three stages namely alkalization, bleaching treatment and acid hydrolysis treatment. Morphological analysis was performed by field emission scanning electron microscopy (FESEM) and transmission electron microscopy (TEM). TEM results revealed that the isolated nanocellulose had the average diameter and length of 21.8±11.1nm and of 547.3±23.7nm, respectively. Fourier transform infrared (FTIR) spectroscopy proved that the non-cellulosic polysaccharides components were progressively removed during the chemically treatment, and the final derived materials composed of cellulose parent molecular structure. X-ray diffraction (XRD) study showed that the crystallinity of yielded product had been improved after each successive treatments subjected to the treated fiber. The prepared nano-dimensional cellulose demonstrated a network-like structure with higher crystallinity (73%) than that of untreated fiber (33%), and possessed of good thermal stability which is suitable for nanocomposite material.
    Matched MeSH terms: Nanostructures/chemistry*
  17. Mohd Bakhori SK, Mahmud S, Ling CA, Sirelkhatim AH, Hasan H, Mohamad D, et al.
    Mater Sci Eng C Mater Biol Appl, 2017 Sep 01;78:868-877.
    PMID: 28576061 DOI: 10.1016/j.msec.2017.04.085
    ZnO with two different morphologies were used to study the inhibition of Streptococcus sobrinus and Streptococcus mutans which are closely associated with tooth cavity. Rod-like shaped ZnO-A and plate-like shaped ZnO-B were produced using a zinc boiling furnace. The nanopowders were characterized using energy filtered transmission electron microscopy (EFTEM), X-ray diffraction (XRD), photoluminescence (PL) spectroscopy, Raman spectroscopy and dynamic light scattering (DLS) to confirm the properties of the ZnO polycrystalline wurtzite structures. XRD results show that the calculated crystallite sizes of ZnO-A and ZnO-B were 36.6 and 39.4nm, respectively, whereas DLS revealed particle size distributions of 21.82nm (ZnO-A) and 52.21nm (ZnO-B). PL spectra showed ion vacancy defects related to green and red luminescence for both ZnO particles. These defects evolved during the generation of reactive oxygen species which contributed to the antibacterial activity. Antibacterial activity was investigated using microdilution technique towards S. sobrinus and S. mutans at different nanopowder concentrations. Results showed that ZnO-A exhibited higher inhibition on both bacteria compared with ZnO-B. Moreover, S. mutans was more sensitive compared with S. sobrinus because of its higher inhibition rate.
    Matched MeSH terms: Nanostructures/chemistry*
  18. Soon G, Pingguan-Murphy B, Akbar SA
    J Mech Behav Biomed Mater, 2017 04;68:26-31.
    PMID: 28135639 DOI: 10.1016/j.jmbbm.2017.01.028
    This study utilizes the technique of self-assembly to fabricate arrays of nanoislands on (001)-oriented yttria-stabilized zirconia single crystal substrates with miscut of 10° toward <110> direction. These self-assembled nanostructures were annealed at 1100°C for 5h upon doping with 10mol% gadolinium-doped ceria (GDC) by powder-suspension based method. X-Ray diffraction result showed that the miscut substrate after doping GDC was in the cubic phase. Energy dispersive X-ray (EDX) illustrates that the nanopatterned material contains all the elements from the GDC source and yttria-stabilized zirconia (YSZ) substrate. It also demonstrates a higher surface roughness and a more hydrophilic surface. The nanostructured materials were subsequently used for an in vitro study using a human fetal osteoblastic cell line (hFOB). An improved spreading, enhanced cell proliferation and up-regulated alkaline phosphatase activity (ALP) were observed on the nanopatterned substrates compared to the control substrates. Calcium deposits, which were stained positively by Alizarin Red S, appeared to be more abundant on the nanopatterned surfaces on day 7. The overall findings suggest that post fabrication treatment with surface modification such as creating a nanostructure (e.g. nanopatterns) can improve biocompatibility.
    Matched MeSH terms: Nanostructures/chemistry*
  19. Khan SS, Kour D, Kaur T, Sharma A, Kumar S, Kumari S, et al.
    Curr Microbiol, 2024 Jul 01;81(8):251.
    PMID: 38954017 DOI: 10.1007/s00284-024-03772-z
    A new area of biotechnology is nanotechnology. Nanotechnology is an emerging field that aims to develope various substances with nano-dimensions that have utilization in the various sectors of pharmaceuticals, bio prospecting, human activities and biomedical applications. An essential stage in the development of nanotechnology is the creation of nanoparticles. To increase their biological uses, eco-friendly material synthesis processes are becoming increasingly important. Recent years have shown a lot of interest in nanostructured materials due to their beneficial and unique characteristics compared to their polycrystalline counterparts. The fascinating performance of nanomaterials in electronics, optics, and photonics has generated a lot of interest. An eco-friendly approach of creating nanoparticles has emerged in order to get around the drawbacks of conventional techniques. Today, a wide range of nanoparticles have been created by employing various microbes, and their potential in numerous cutting-edge technological fields have been investigated. These particles have well-defined chemical compositions, sizes, and morphologies. The green production of nanoparticles mostly uses plants and microbes. Hence, the use of microbial nanotechnology in agriculture and plant science is the main emphasis of this review. The present review highlights the methods of biological synthesis of nanoparticles available with a major focus on microbially synthesized nanoparticles, parameters and biochemistry involved. Further, it takes into account the genetic engineering and synthetic biology involved in microbial nanobiosynthesis to the construction of microbial nanofactories.
    Matched MeSH terms: Nanostructures/chemistry
  20. Muthoosamy K, Bai RG, Abubakar IB, Sudheer SM, Lim HN, Loh HS, et al.
    Int J Nanomedicine, 2015;10:1505-19.
    PMID: 25759577 DOI: 10.2147/IJN.S75213
    PURPOSE: A simple, one-pot strategy was used to synthesize reduced graphene oxide (RGO) nanosheets by utilizing an easily available over-the-counter medicinal and edible mushroom, Ganoderma lucidum.

    METHODS: The mushroom was boiled in hot water to liberate the polysaccharides, the extract of which was then used directly for the reduction of graphene oxide. The abundance of polysaccharides present in the mushroom serves as a good reducing agent. The proposed strategy evades the use of harmful and expensive chemicals and avoids the typical tedious reaction methods.

    RESULTS: More importantly, the mushroom extract can be easily separated from the product without generating any residual byproducts and can be reused at least three times with good conversion efficiency (75%). It was readily dispersible in water without the need of ultrasonication or any surfactants; whereas 5 minutes of ultrasonication with various solvents produced RGO which was stable for the tested period of 1 year. Based on electrochemical measurements, the followed method did not jeopardize RGO's electrical conductivity. Moreover, the obtained RGO was highly biocompatible to not only colon (HT-29) and brain (U87MG) cancer cells, but was also viable towards normal cells (MRC-5).

    CONCLUSION: Besides being eco-friendly, this mushroom based approach is easily scalable and demonstrates remarkable RGO stability and biocompatibility, even without any form of functionalization.

    Matched MeSH terms: Nanostructures/chemistry*
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