MyMedR

Fulltext Endonasal endoscopic resection of intranasal haemangioma

Ahmad R, Norie A

Med J Malaysia, 2006 Dec;61(5):644-6.

Intranasal haemangioma is quite rare. This tumor may be confused with other intranasal vascular tumor such as juvenile nasopharyngeal angiofibroma (JNA), glomus tumors as well as other tumor such as angiosarcoma and leiomyoma. Juvenile nasopharyngeal angiofibroma is the most common vascular tumor encountered in nasal cavity. A definitive histology diagnosis pre-operatively is difficult to be obtained as the biopsy may lead into severe uncontrolled bleeding. The final diagnosis very much depends on histology after the tumor excision. Complete surgical resection of the tumor is the standard approach. In this report we describe our surgical management in approaching intranasal haemangioma endoscopically and this pathology can be considered as one of differential diagnosis for unilateral nasal mass.

Matched MeSH terms: Paranasal Sinus Neoplasms/pathology; Paranasal Sinus Neoplasms/surgery*

Fulltext Endoscopic management of sinonasal inverted papilloma

Bathma S, Harvinder S, Philip R, Rosalind S, Gurdeep S

Med J Malaysia, 2011 Mar;66(1):15-8.

PMID: 23765136 MyJurnal

Inverted papillomas (IPs) are benign sinonasal epithelial tumors that are locally aggressive and has a preponderance to recur if incompletely excised. This is a retrospective report describing 13 patients who underwent endoscopic excison from March 2004 to December 2010. Data was summarized into age, sex, location of tumor, surgical outcome and disease free status. Majority of the patients were males with the remaining 3 females, with a mean age of 50.9 years (range 24-76 years). Two patients needed an additional procedure of endoscopic dacrocystorhinostomy (EDCR) for epiphora. Out of the 13 patients surveyed, three patients underwent revision surgery for recurrences, of which one was a referred from another instituition. All patients are currently disease free. The mean follow-up period is 40 months.

Matched MeSH terms: Paranasal Sinus Neoplasms*

Fulltext An extensive sinonasal osteosarcoma mimicking chondrosarcoma

Shahid H, Baharudin A, Halim AS, Biswal BM, Jihan WS

Med J Malaysia, 2007 Jun;62(2):171-2.

PMID: 18705458 MyJurnal

Osteosarcoma is a rare tumour in the sinonasal region. Early diagnosis is essential for adequate management and better prognosis and this requires a meticulous histopathological examination. Reported is a case of osteosarcoma misdiagnosed as chondrosarcoma and treated by surgery followed by radiotherapy. However, appropriate diagnosis and pre-operative chemotherapy would have been significant in the prognosis. The pitfall of accurate diagnosis and the subsequent treatment is discussed in order to find the ways to maximize five years survival which is not more than 25% in this type of lesions.

Matched MeSH terms: Paranasal Sinus Neoplasms/diagnosis*; Paranasal Sinus Neoplasms/pathology; Paranasal Sinus Neoplasms/therapy

Fulltext Challenges in the treatment of sinonasal undifferentiated carcinoma: a ray of hope

Norleza AN, Gendeh BS

Med J Malaysia, 2005 Aug;60(3):281-5.

PMID: 16379180 MyJurnal

We studied nine cases of SNUCs presented to the Department of Otorhinolaryngology, Hospital University Kebangsaan Malaysia from 1999 to 2003. There were 8 males and 1 female with ages ranging from 24 to 78 years (mean 46.5y). The racial distribution consisted of 5 Chinese (55.5%), 3 Malays (33.3%) and 1 Indian (11.1%). Three patients were Kadish B (33.3%) and six were Kadish C (66.6%) by classification. In our series 2 years survival was 26.3% and median survival time was 14.2 months.

Matched MeSH terms: Paranasal Sinus Neoplasms/mortality; Paranasal Sinus Neoplasms/pathology; Paranasal Sinus Neoplasms/surgery*

Fulltext Transnasal endoscopic medial maxillectomy: Changing trend in the management of sinonasal inverted papilloma – report of two Case

Zamzil Amin Ashaari, Shamim Ahmed Khan

International Medical Journal Malaysia, 2007;6(1):1-7.

MyJurnal

The current advents of endoscopic techniques have enabled rhinologists to treat inverted papilloma of the nose with a more favourable surgical morbidity. However the supposed changing trend in surgical management of sinonasal inverted papilloma from external approach to endoscopic technique has to come with caution as certain guidelines must be made to ensure its effectiveness. Since the introduction of purely transnasal endoscopic medial maxillectomy in 1981, many authors have published their experiences in this field. This article reviews some of the literatures regarding the management aspect of inverted papilloma particularly focusing on the endoscopic medial maxillectomy and relate with our own experience in management of this tumour endoscopically.

Matched MeSH terms: Paranasal Sinus Neoplasms

Metastasis to the sinonasal tract from sigmoid colon adenocarcinoma

bin Sabir Husin Athar PP, bte Ahmad Norhan N, bin Saim L, bin Md Rose I, bte Ramli R

Ann Acad Med Singap, 2008 Sep;37(9):788-3.

PMID: 18989497

INTRODUCTION: Metastatic adenocarcinoma from the gastrointestinal tract to the sinonasal tract is rare. The histological morphology of this lesion is indistinguishable from the colonic variant of primary sinus adenocarcinoma or intestinal-type adenocarcinoma (ITAC).

CLINICAL PICTURE: This is a report of a case of metastatic adenocarcinoma of colorectal origin to the paranasal sinuses in a 52-year-old female who was previously treated for adenocarcinoma of the sigmoid colon. A histologic study of the surgical specimen from the sinonasal cavity demonstrated a tumour identical to the patient's prior primary tumour of the colon. The sinonasal neoplastic tissue showed marked positivity for carcinoembryonic antigen and expressed cytokeratin 20, which differentiates metastatic colonic adenocarcinoma from ITAC.

TREATMENT/OUTCOME: The patient received palliative radiation but died 3 months after the diagnosis.

CONCLUSION: Distinguishing metastatic adenocarcinoma from gastrointestinal tract from ITAC can be difficult. In view of the resemblance, immunohistochemical staining can help in differentiating them. It is important to recognise these as metastatic lesions as the treatment is mainly palliative.

Matched MeSH terms: Paranasal Sinus Neoplasms/metabolism; Paranasal Sinus Neoplasms/radiotherapy; Paranasal Sinus Neoplasms/secondary*

Undifferentiated carcinoma of the sinuses and cranial basis successfully treated with radiochemotherapy. A case report

Chandrasekaran S, Baba AA, Othman N, Jayakumar CR

Chemotherapy, 1994 Sep-Oct;40(5):357-61.

PMID: 7956460

The frustration and disappointment in managing advanced cancers of the nose and paranasal sinuses are well known. We report a case of a successful treatment of such a tumour in a 37-year-old soldier, using a combination of therapy including surgery, chemotherapy and radiation. Each mode of treatment is discussed.

Matched MeSH terms: Paranasal Sinus Neoplasms/drug therapy; Paranasal Sinus Neoplasms/radiotherapy; Paranasal Sinus Neoplasms/surgery; Paranasal Sinus Neoplasms/therapy*

Fulltext Management of sinonasal inverted papillomas: endoscopic medial maxillectomy

Harvinder S, Rosalind S, Mallina S, Gurdeep S

Med J Malaysia, 2008 Mar;63(1):58-60.

PMID: 18935736

Inverted papillomas (IPs), although histologically benign, are aggressive lesions that may recur after excision. They usually present as unilateral firm, bulky, red and vascular masses. The objective of this case series is to discuss the surgical treatment options for IPs and to review the literature with a special emphasis on our experience with endoscopic medial maxillectomy. A retrospective review of the data of patients with IP treated by endoscopic medial maxillectomy was performed. This report describes the surgical experience with five patients with IP arising from various sites on the lateral nasal wall. Data points collected included age, sex, location(s) and histopathological diagnosis (benign IP vs IP with dysplasia or carcinoma). The surgical treatment strategy, need for adjunct approaches, complications, recurrence rates and length of follow-up were determined. The average age was 51.2 years (range, 35-62 years), with four males and one female. All cases were managed with endoscopic medial maxillectomy as the primary surgical modality. Adjunctive approaches included endoscopic dacryocystorhinostomy (EDCR) in two patients who presented with epiphora post-operatively. Intra-operative frozen section was performed in all cases to ensure complete tumor removal. No intra-operative complications were encountered. No recurrences were noted in these patients, with a mean follow-up period of 23 months.

Matched MeSH terms: Paranasal Sinus Neoplasms/surgery*

Teratocarcinosarcoma of the nasal cavity and ethmoid

Sharma HS, Abdullah JM, Othman NH, Muhamad M

J Laryngol Otol, 1998 Jul;112(7):682-6.

PMID: 9775307

Sinonasal teratocarcinosarcoma is very unusual malignant neoplasm histologically consisting of an epithelial element and one or more mesenchymal components. This is a report of teratocarcinosarcoma, in a 74-year-old male, involving the right nasal cavity and ethmoids with intracranial extension. The tumour was totally resected via the craniofacial approach and the patient was given post-operative chemotherapy. Extensive tumour necrosis, rapid growth and local destruction are the prominent features of this tumour. The clinical presentation, pathological features and clinical course of this rare malignancy are discussed with a review of the literature.

Matched MeSH terms: Paranasal Sinus Neoplasms/pathology*

Fulltext Intermittent respiratory obstruction secondary to a solitary fibrous tumour

Shashinder S, Kuljit S, Rahmat O, Usha DA, Gopala GK

Med J Malaysia, 2006 Oct;61(4):501-2.

PMID: 17243534 MyJurnal

There have been fourteen cases of solitary fibrous tumour reported as originating from the paranasal sinuses. Here we report a case of solitary fibrous tumour that involved the right nasal cavity with extension into the oropharynx causing stertor and intermittent respiratory obtruction. Histopathology examination revealed the tumuor cells expressed CD34 turnout marker.

Matched MeSH terms: Paranasal Sinus Neoplasms/complications*; Paranasal Sinus Neoplasms/pathology

Fulltext Sino-nasal hemangiopericytoma--a rare tumor

Vikneswaran T, Gendeh BS, Tan VES, Phang KS, Saravanan K

Med J Malaysia, 2005 Oct;60(4):485-8.

PMID: 16570712

Hemangiopericytoma is a very rare angiogenic tumor. In the nasal cavity, it can be considered malignant. It occurs in various parts of the body but those in the nasal cavity account for only 5% of total cases. Less than 200 cases have been reported worldwide involving the nose and paranasal sinuses. Due to its rarity a proper line of management has not been established to tackle this tumour. This article highlights two cases of hemangiopericytoma (HPC), one in an adult and the other in a child, presenting as an intranasal mass.

Matched MeSH terms: Paranasal Sinus Neoplasms/diagnosis; Paranasal Sinus Neoplasms/surgery

Malignant paraganglioma of frontoethmoidal region

Sharma HS, Madhavan M, Othman NH, Muhamad M, Abdullah JM

Auris Nasus Larynx, 1999 Oct;26(4):487-93.

PMID: 10530746

Nonchromaffin paragangliomas are unusual tumours arising from widely distributed paraganglionic tissues probably of neural crest origin. In the head and neck region they are usually seen as carotid body or jugulotympanic tumours. Other rarely reported sites in the head and neck region are the orbit, nose and larynx. This report deals with a case of sinonasal paraganglioma which was initially treated with surgery and radiotherapy. Twenty two years later the tumour recurred and showed a rapid growth due to malignant transformation which we believe is late effect of radiotherapy. The clinical features, histopathology and role of radiotherapy in sinonasal paragangliomas together with a review of the medical literature have been discussed.

Matched MeSH terms: Paranasal Sinus Neoplasms/pathology*; Paranasal Sinus Neoplasms/surgery

Tumefactive fibroinflammatory lesion of the head and neck

Said H, Razi Hadi A, Akmal SN, Lokman S

J Laryngol Otol, 1988 Nov;102(11):1064-7.

PMID: 3209947 DOI: 10.1017/s0022215100107297

The term tumefactive fibroinflammatory lesion is used to describe an unusual fibrosclerosing disorder that behaves in a malignant way clinically but is histologically benign. Lesions in the head and neck are believed to be part of the broader fibrosclerosing syndrome which include pseudotumour of the orbit, Reidel's thyroiditis, sclerosing cholangitis and mediastinal fibrosis. Clinical diagnosis is often difficult and relies heavily on histopathology. Steroid therapy is suggested as the first line of management, while surgery or radiation therapy is reserved for failures.

Matched MeSH terms: Paranasal Sinus Neoplasms/pathology; Paranasal Sinus Neoplasms/surgery*

Fulltext Malignant non-Hodgkin's lymphomas of the nose and paranasal sinuses

Tan J, Said H, Chong SM

Med J Malaysia, 1988 Mar;43(1):49-54.

PMID: 3244320

Matched MeSH terms: Paranasal Sinus Neoplasms/diagnosis; Paranasal Sinus Neoplasms/pathology*

Orbital rhabdomyosarcoma in an HIV positive child

Khairy-Shamel ST, Shatriah I, Adil H, Zunaina E, Bakiah S, Rohaizan Y, et al.

Orbit, 2008;27(5):388-90.

PMID: 18836940 DOI: 10.1080/01676830802336629

We reported a case of orbital rhabdomyosarcoma with an intracranial extension in an HIV-infected child. It was an uncommon sarcoma in a retroviral-positive patient that resulted in a diagnostic and therapeutic dilemma. The child is currently asymptomatic following surgery, chemotherapy, and reinstitution of highly active retroviral therapy (HAART).

Matched MeSH terms: Paranasal Sinus Neoplasms/pathology*; Paranasal Sinus Neoplasms/radiography; Paranasal Sinus Neoplasms/surgery

A rare case of large sphenoethmoidal osteoma

Nazli Z, Abdul Fattah AW

Med J Malaysia, 2017 02;72(1):60-61.

PMID: 28255144 MyJurnal

Osteoma is the most common benign tumour of the nose and paranasal sinuses. However, involvement of the sphenoid sinus by osteoma is rare. Most of the time, patients with paranasal sinus osteoma are asymptomatic. However, symptoms may present, depending on the location and extension of the tumour. We report a case of a patient with sphenoethmoidal osteoma found incidentally on imaging, with evidence of impingement onto the optic nerve at the optic canal. However, the patient was asymptomatic. He was surgically treated using the endoscopic transnasal approach.

Matched MeSH terms: Paranasal Sinus Neoplasms

Metastatic hepatocellular carcinoma presenting as a sphenoid sinus mass and meningeal carcinomatosis

Hashim H, Rahmat K, Abdul Aziz YF, Chandran PA

Ear Nose Throat J, 2014 Jun;93(6):E20-3.

PMID: 24932824

We report the case of a 30-year-old woman who was referred to us for evaluation of a 2-week history of fever, headache, vomiting, bilateral ptosis, and blurred vision. Imaging obtained by the referring institution had identified a sphenoid sinus mass and diffuse meningeal infiltration, which was thought to represent an infective process. We subsequently identified the mass as a metastatic hepatocellular carcinoma (HCC). The patient was placed under palliative care, and she died 1 month later. Metastases to the sphenoid sinus from any primary source are very rare, and they are generally not considered in the radiologic differential diagnosis. HCC is known to metastasize to the lung, lymph nodes, and musculoskeletal system; again, reported cases of metastasis to the sphenoid sinus are rare. Indeed, our review of the English-language literature found only 6 previously reported cases of sinonasal metastasis of a primary HCC. A diagnosis of a sinonasal metastasis is more difficult in a patient who has no previous diagnosis of a primary malignancy. In presenting this case, our aim is to remind readers of this possibility.

Matched MeSH terms: Paranasal Sinus Neoplasms/secondary*

A case of chronic subdural hematoma following lumbar drainage for the management of iatrogenic cerebrospinal fluid rhinorrhea: pitfalls and lessons

Tan VE, Liew D

Ear Nose Throat J, 2013 Oct-Nov;92(10-11):513-5.

PMID: 24170465

Chronic subdural hematoma as a complication of lumbar drain placement for the management of iatrogenic cerebrospinal fluid (CSF) leak has not been previously documented in the literature. We describe such a case in a 69-year-old man who presented with right nasal obstruction secondary to an inverted papilloma involving the paranasal sinuses. The patient underwent endoscopic sinus surgery, which included a medial maxillectomy. Surgery was complicated by a small CSF leak, which was repaired intraoperatively. Five days later, the patient experienced CSF rhinorrhea, and a lumbar drain was inserted. He developed overdrainage symptoms but was well when he was discharged. However, 22 days later he returned with right hemiparesis. Computed tomography of the brain showed a left frontoparietal subdural hematoma with a mass effect. The neurosurgical team performed an emergency drainage procedure, and the patient experienced a complete neurologic recovery. We discuss the pitfalls of lumbar drainage, the possible pathophysiology of overdrainage, and the lessons learned from this case.

Matched MeSH terms: Paranasal Sinus Neoplasms/surgery*

Adenoid cystic carcinoma of the sinonasal tract: outcome of endonasal endoscopic surgery at five-year follow up

Gendeh BS, Zahedi FD, Ahmad H, Kew TY

J Laryngol Otol, 2013 May;127(5):511-5.

PMID: 23570560 DOI: 10.1017/S0022215113000480

To study the outcome of endonasal endoscopic surgery for adenoid cystic carcinoma of the sinonasal tract over a five-year follow-up period.

Matched MeSH terms: Paranasal Sinus Neoplasms/surgery*

Fulltext Endoscopic-assisted craniofacial resection: a case series and post-operative outcome

Gendeh BS, Salina H, Selladurai B, Jegan T

Med J Malaysia, 2007 Aug;62(3):234-7.

PMID: 18246914 MyJurnal

Craniofacial resection is commonly performed in the surgical resection of sinonasal tumours involving anterior skull base. It entails a bicoronal scalp flap with lateral rhinotomy or an extended lateral rhinotomy to expose the anterior skull base. Transfacial approach is necessary in the resection of the nasal part of the tumour. The choice of surgical approach is based heavily on the surgeon's experience and training. The results of endoscopic-assisted craniofacial resection for sinonasal tumours performed in our center in eight patients from 1998 to 2005 were reviewed. There were seven males and one female with age ranging from 18 to 62 years (mean 42.4 years). There was each a case of mature teratoma, poorly differentiated squamous cell carcinoma, undifferentiated squamous cell carcinoma, olfactory neuroblastoma, fibrous dysplasia, inverted papilloma and two cases of sinonasal neuroendocrine carcinoma. The mean follow up duration for these eight patients post surgery was 21.4 months. Out of eight patients, five underwent surgery with no adverse complications. The complications encountered were a cerebrospinal leak and a postoperative transient V and VI cranial nerve palsy. One patient with sinonasal undifferentiated carcinoma died of lung metastasis at 11 months post-surgery. The endoscopic-assisted craniofacial resection is a highly useful surgical technique to avoid the unsightly facial scar of the lateral rhinotomy or the Weber-Ferguson incision, postoperative paranasal sinuses infection and avoidance of tracheostomy in selected cases. We found that this approach has lower morbidity rate in selected cases.

Matched MeSH terms: Paranasal Sinus Neoplasms/surgery*

Displaying publications 1 - 20 of 23 in total