Displaying all 15 publications

  1. Chapter of Rheumatologists, Singapore Society of Rheumatology, Chapter of Infectious Disease Physicians, Society of Infectious Disease Singapore
    Singapore Med J, 2016 Feb;57(2):98-100.
    PMID: 27326437
    Matched MeSH terms: Rheumatology/history*
  2. Mok TM
    Int J Rheum Dis, 2015 Jun;18(5):583-6.
    PMID: 26082351 DOI: 10.1111/1756-185X.12676
    Matched MeSH terms: Rheumatology*
  3. Lau CS, Chia F, Harrison A, Hsieh TY, Jain R, Jung SM, et al.
    Int J Rheum Dis, 2015 Sep;18(7):685-713.
    PMID: 26334449 DOI: 10.1111/1756-185X.12754
    Rheumatoid arthritis is a chronic inflammatory condition that affects approximately 1% of the world's population. There are a wide number of guidelines and recommendations available to support the treatment of rheumatoid arthritis; however, the evidence used for these guidelines is predominantly based on studies in Caucasian subjects and may not be relevant for rheumatoid arthritis patients in the Asia-Pacific region. Therefore, the Asia Pacific League of Associations for Rheumatology established a Steering Committee in 2013 to address this issue.
    Matched MeSH terms: Rheumatology/standards*
  4. Arshad A, Kong KO, Ooi KK
    J Clin Rheumatol, 2007 Apr;13(2):59-62.
    PMID: 17414529
    Fibromyalgia syndrome (FMS) is a common but controversial condition. There appears to be different level of belief of its existence and awareness. We set out to explore the variations of perceptions and awareness of this condition among rheumatologists from the Southeast Asia (SEA) region.
    Matched MeSH terms: Rheumatology/standards*
  5. Arshad A, Kong KO
    Singapore Med J, 2007 Jan;48(1):25-30.
    PMID: 17245512
    Fibromyalgia syndrome (FMS) is a common but controversial condition. There appears to be different levels of belief of its existence and awareness. We set out to explore the variations of perceptions and awareness of this condition among rheumatologists from Malaysia and Singapore.
    Matched MeSH terms: Rheumatology*
  6. Chai, Win Lin, Phang, Yuen Hoong, Chong, Hwee Cheng
    Tumoral calcinosis is an uncommon condition which
    has been described to exist in primary and secondary
    forms. A lack of awareness of this entity can lead to
    unnecessary procedures and incorrect management.
    We report a case of a patient on peritoneal dialysis who
    presented with multiple painful joint swellings to the
    orthopaedic department. An initial diagnosis of septic
    arthritis was made, then revised to chronic tophaceous
    gout and referred to the rheumatology unit.
    Matched MeSH terms: Rheumatology
  7. Gupta ED, Goh EM, Gun SC, Hussein H, Shahril NS, Yeap SS, et al.
    EXCLI J, 2013;12:521-2.
    PMID: 27034635
    Matched MeSH terms: Rheumatology
  8. Hilmi Abdullah
    Febuxostat is a non-purine-selective oral xanthine oxidase inhibitor drug,
    and is an alternative to Allopurinol to lower serum uric acid in gout patients. It is
    probably more effective than Allopurinol, however, its use is limited because of its cost
    and availability. Allopurinol has been the mainstay treatment for gout for about 50
    years. However, its use has been associated with allergic reactions especially in patients
    with renal impairment.The objective of this study was to describe HTAA Rheumatology
    Unit experiences with Febuxostat in the management of gout. (Copied from article).
    Matched MeSH terms: Rheumatology
  9. Ong SG
    Malays Fam Physician, 2013;8(3):31-33.
    PMID: 25893055 MyJurnal
    Tendon rupture is a rare complication that occurs in patients receiving corticosteroid therapy. We report a case of a middle-aged man with mixed connective tissue disease who presented with spontaneous biceps tendon rupture 5 weeks after initiation of high-dose corticosteroid therapy. Musculoskeletal ultrasonography was performed at the clinic and helped to confirm the diagnosis. It is a new imaging modality that is increasingly used in rheumatology clinics in Malaysia as it serves as an extension to physical examination. Musculoskeletal ultrasonography is preferred by patients as it is noninvasive, does not involve ionising radiation, painless, relatively inexpensive and can be performed readily at the clinic.
    Matched MeSH terms: Rheumatology
  10. Teh CL, Wong JS
    Clin. Rheumatol., 2011 May;30(5):615-21.
    PMID: 20886247 DOI: 10.1007/s10067-010-1583-3
    The aim of our study is to describe the impact of tight control strategy on the care of RA patients in Sarawak General Hospital. We performed a prospective study of all patients with a diagnosis of RA who received treatment at the Rheumatology Clinic in Sarawak General Hospital over a 1-year period. Systematic DAS-driven treatment adjustments aimed to achieve low disease activity (DAS 28-ESR <2.6) were carried out in the clinic over the 1-year period. Disease activity and treatment regimes of all 142 patients were collected for at baseline and 1 year later for statistical analysis. Our patients have a significantly lower DAS 28 with a mean of 2.99 ± 0.95 compared with baseline of 4.31 ± 1.34 (p < 0.000). More patients were in remission 1 year later compared to baseline (36.6% vs 11.3%). Tight control strategy has a positive impact on the care of RA patients in our centre. By optimising the care of RA through tight control strategy, RA can be better controlled in our centre.
    Matched MeSH terms: Rheumatology/methods*
  11. Devaraj NK
    Ethiop J Health Sci, 2018 Jan;28(1):101-102.
    PMID: 29622913
    Background: Rheumatoid arthritis is a devastating condition. More so, the diagnosis of seronegative rheumatoid arthritis is often fraught off with much uncertainty and that leads to further suffering to the unfortunate patient.

    Case Details: This is a case of Madam A, who presented with many non-specific symptoms and signs involving many systems which was finally diagnosed as seronegative rheumatoid arthritis. This case explores the challenges in reaching this uncommon diagnosis and how anti-inflammatory drugs can bring a miraculous relief to the patient's suffering.

    Conclusion: The diagnosis of seronegative rheumatoid arthritis often presents a real challenge to the medical practitioner and often requires multiple visits and/or shared multidisciplinary care for confirmation of the diagnosis. Once diagnosed and treated with disease modifying anti- rheumatic drugs, often there is a miraculous relief to the patient's suffering.

    Matched MeSH terms: Rheumatology
  12. Ruhaila AR, Chong HC
    Med. J. Malaysia, 2018 Aug;73(4):226-232.
    PMID: 30121685 MyJurnal
    OBJECTIVE: To determine the prevalence, correlates and independent predictors of self-reported depression, anxiety and stress in Rheumatoid arthritis (RA) patients in Hospital Melaka.

    METHODS: This was a cross-sectional survey using convenient sampling of 192 RA patients who attended the Rheumatology Clinic outpatient appointment, Hospital Melaka from June 2013 to December 2013. Depression, Anxiety and Stress Scale (DASS21) questionnaire was used to evaluate symptoms of depression, anxiety and stress. RA disease activity was assessed using the DAS28-ESR formula. Functional status was assessed via the Health Assessment Questionnaire Disability Index (HAQ-DI).

    RESULTS: Out of 189 completed questionnaires, 46%(n=86) patients reported psychological distress symptoms, and 25%(n=48) experienced more than one negative emotional states. The prevalence of depression, anxiety and stress among our patients were 23.3%(n=44), 42.3%(n=80) and 20.1%(n=38) respectively. There were significant positive correlations (p<0.05) between these psychological symptoms with disease activity, number of tender joints, general health, pain and HAQ score. Age was inversely correlated with depression, anxiety and stress. Higher number of swollen joints correlated positively with depression but not with anxiety and stress. HAQ was the only independent predictor for depression (Odds Ratio [OR]=2.07; 95%CI: 1.19 to 3.61) and anxiety (OR=1.81; 95%CI: 1.1 to 3.0) whilst pain was found to be independent predictor for stress (OR=1.04; 95%CI: 1.0 to 1.1).

    CONCLUSION: The incidence of depression and anxiety in our Malaysian sample of RA patient was comparable to that observed in Caucasian populations. Functional status was an independent predictor of depression and anxiety, whereas pain was an independent predictor of stress.

    Matched MeSH terms: Rheumatology
  13. Martin JL, Vlachou PA
    Radiology, 2018 Nov;289(2):568-571.
    PMID: 30332363 DOI: 10.1148/radiol.2018162112
    History A 58-year-old woman was seen in the rheumatology clinic for bilateral wrist and knee pain that was unresponsive to physiotherapy and intra-articular steroid injections. Remote fracture of the left tibia from a motor vehicle collision was reported and was previously treated with conservative management. Serologic work-up for inflammatory disease was negative. The patient reported no prior surgical or medical history. Social history revealed remote immigration from Malaysia. Radiographs of the hands and knees were obtained ( Figs 1 - 4 ). [Figure: see text][Figure: see text][Figure: see text][Figure: see text].
    Matched MeSH terms: Rheumatology
  14. Arkachaisri T, Tang SP, Daengsuwan T, Phongsamart G, Vilaiyuk S, Charuvanij S, et al.
    Rheumatology (Oxford), 2017 03 01;56(3):390-398.
    PMID: 27994096 DOI: 10.1093/rheumatology/kew446
    Objectives: To examine the descriptive epidemiology of the patient population referred to paediatric rheumatology centres (PRCs) in Southeast Asia (SEA) and to compare the frequency of conditions encountered with other PRC populations.

    Methods: A web-based Registry for Childhood Onset Paediatric Rheumatic Diseases was established in 2009 and seven PRCs in four SEA countries, where paediatric rheumatologists are available, participated in a prospective 24 month data collection (43 months for Singapore).

    Results: The number of patients analysed was 4038 (788 from Malaysia, 711 from the Philippines, 1943 from Singapore and 596 from Thailand). Over 70% of patients evaluated in PRCs in Malaysia, the Philippines and Thailand had rheumatic diseases (RDs), as compared with one-half of the proportion seen in Singaporean PRCs, which was similar to the Western PRC experience. Among RDs diagnosed (n = 2602), JIA was the most common disease encountered in Malaysia (41%) and Thailand (61%) as compared with systemic vasculitides in the Philippines (37%) and Singapore (35%) among which Henoch-Schönlein purpura was the most prevalent. SLE and related diseases were more common, but idiopathic pain syndrome and abnormal immunological laboratory tests were rarer than those seen in the West. JIA subtype distributions were different among countries. Among non-RDs (n = 1436), orthopaedic and related conditions predominated (21.7-59.4%).

    Conclusion: The frequencies of RDs seen by SEA PRCs were different from those in the West. Systemic vasculitides and SLE were common in addition to JIA. Paediatric rheumatologist availability and healthcare accessibility partially explain these observed discrepancies.

    Matched MeSH terms: Rheumatology
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