MyMedR

Bul Keluarga, 1977 Sep;89:1-2.

Matched MeSH terms: Contraceptives, Oral*

Fulltext Oral contraceptives postdatism as a complication

Teo MYK, Teo BSE

Med J Malaysia, 1982 Dec;37(4):338-43.

Women who conceived within 4 months of cessation of oral contraceptives have five times more postdatism (term plus 14 days or more) compared to the non pal users. Also postdatism is severe if they conceive within 4 months of cessation of oral contraceptives. In pill users, routine induction. at term plus 14 days would result in unacceptably high induction rate, iatrogenic prematurity and possibly high caesarean rates. This is the conclusion of a prospective study of 186 pill users of which 37 were postdate out of 1496 pregnancies.

Matched MeSH terms: Contraceptives, Oral/adverse effects*

A case of thrombophlebitis in a woman on oral contraceptive

Rajakumar MK

Med J Malaya, 1970 Sep;25(1):68-9.

PMID: 4249501

Matched MeSH terms: Contraceptives, Oral/adverse effects*

TRENDS IN EDUCATION IN OBSTETRICS AND GYNAECOLOGY: A FORUM

MACAFEE CH, MCKELVEY JL, CHESTERMAN JN, MEARES SD, BROWNE AD

Med J Malaysia, 1963 Jun;17:244-52.

PMID: 14060501

Matched MeSH terms: Contraceptives, Oral*

The use of combined hormonal contraceptives amid the COVID-19 pandemic

Kow CS, Mustafa ZU, Hasan SS

Eur J Contracept Reprod Health Care, 2021 02;26(1):85-86.

PMID: 33245006 DOI: 10.1080/13625187.2020.1849618

Matched MeSH terms: Contraceptives, Oral, Hormonal

A prospective study of a monophasic oral contraceptive containing 30 mcg ethinyl oestradiol and 150 mcg desogestrel (Marvelon)

Ismail MT

Malays J Reprod Health, 1994 Jun;12(1):43-8.

PMID: 12320338

PIP: Marvelon, a monophasic oral contraceptive (OC) containing 30 mcg of ethinyl estradiol and 150 mcg of desogestrel, has been available to Malaysian women through the national family planning program since 1982. To assess the safety, effectiveness, and side effects associated with this OC, 247 women who requested the pill were enrolled in a multicenter prospective study that included follow-up after the first, third, and sixth cycles of use. 81% of participants had never used any form of contraception before Marvelon. 194 women (79%) completed the 6-month study. There were no pregnancies recorded. Although women reported a slightly increased incidence of nausea, breast tenderness, and headache in the first treatment cycle, these side effects had abated by the end of the third cycle. After six cycles, mean body weight had decreased by an average of 0.4 kg. Both systolic and diastolic blood pressure were unaffected. An unexpected finding was a decrease in the severity of acne with continuous use of Marvelon. Although both spotting and breakthrough bleeding increased slightly in the first two cycles, irregular bleeding returned to pretreatment levels by the third cycle. The length of the withdrawal bleed in the pill-free week was reduced. The incidence of irregular bleeding and other side effects was substantially lower in this sample of Malaysian women than in Asian and Caucasian Marvelon users surveyed in other studies.

Matched MeSH terms: Contraceptives, Oral; Contraceptives, Oral, Combined*; Contraceptives, Oral, Hormonal

Fulltext The return of fertility after discontinuation of oral contraception in Malaysian women

Hassan J, Kulenthran A, Thum YS

Med J Malaysia, 1994 Dec;49(4):348-50.

PMID: 7674970

The return of fertility after discontinuation of oral contraception was studied in a cross-sectional survey of 61 patients who were desirous of a further pregnancy. For controls, 380 women who did not take any oral contraception were used. Cumulative conception rates in the pill users were reduced but not significantly during the first three (p = 0.15) and six months (p = 0.20). By 12 months this difference was negligible (p = 0.28). We conclude that there is no significant delay in return of fertility following cessation of oral contraception in our group of Malaysian women.

Matched MeSH terms: Contraceptives, Oral/administration & dosage*; Contraceptives, Oral/pharmacology

Fulltext Coagulation profile in women on low-dose oral contraceptive pills

Roshidah I, Khalid H, Baharum Y

Malays J Reprod Health, 1990 Dec;8(2):97-100.

PMID: 12343152

A cross-sectional study looking at the coagulation system was carried out involving 175 women attending the National Population and Family Development Board's Clinic at the Maternity Clinic, General Hospital, Kuala Lumpur. Study subjects comprise of 50 combined low-dose estrogen/progestrogen oral contraceptive (DC) pill users and 75 non-DC users, acting as controls. The subjects were on the pill for a period of one year or more. There were significant shortening of the prothrombin time (PT) and partial thromboplastin time (PIT) in the DC group as compared to the control group. However, the activities of factors II, Vand VIII assayed were not significantly different between the two groups, suggesting that the changes in the PT and PIT were not significant clinically. The effect of long term usage of combined 10w..cJose DC pills does not seem to indicate changes in the coagulation profile of the women in our study.
PIP: The effect of low dose combined oral contraceptives containing 30 mcg ethinyl estradiol and either 150 mcg levonorgestrel or 150 mcg desogestrel on coagulation indices in Malaysian women was examined. 50 women who had been using the pills for 1 year or more, were compared to 75 non-users. All were attending the Maternity Clinic of the General Hospital, Kuala Lumpur. Pill users registered shorter prothrombin time, 11.5 vs. 11.1 seconds (p=0.016), and partial thromboplastin time, 40.1 vs 35.1 seconds (p=0.000). Since there were no significant differences in Factors II, V, VII, or VIII, the overall effects of low-dose pills on coagulation is probably not clinically significant.

Matched MeSH terms: Contraceptives, Oral*; Contraceptives, Oral, Hormonal

A randomised comparative study of Triquilar versus Marvelon: the Malaysian experience

Ismail MT

Malays J Reprod Health, 1991 Jun;9(1):9-17.

PMID: 12317444

PIP:
Health workers in Malaysia randomly assigned either a low-dose triphasic or a low-dose monophasic oral contraceptive (Triquilar and Marvelon, respectively) to 198 women to examine discontinuation rates and reasons for discontinuation. 15.3% of Triquilar women and 9.1% of Marvelon women forgot to take 1 pill at some time during the study while 6.1% and 3% forgot to take at least 3 consecutive pills. There were more complaints and/or complications among Triquilar women than among Marvelon women. The most serious complication was severe headaches (only 1 woman from each group). 2 women in the Marvelon group complained of either generalized itchiness or digestion impairment. Complaints of women in the Triquilar group included localized and generalized itchiness, weight gain, digestion impairment, dryness of vagina, and numbness of extremities. Women in the Triquilar group were more likely to have menstrual complaints than those in the Marvelon group (14.3% vs. 9.1%). The leading menstrual complaint in both groups was spotting (6.1% vs. 4%). No Marvelon women reported menorrhagia, scanty menses, or intermenstrual pelvic pain or discomfort while at least 1 woman did from the Triquilar group. The percentage of women with changes in complaints since admission were the same for both groups. Total discontinuation rates which included lost to follow ups were 46.9% and 40%, respectively. The most common reason for discontinuation for both groups was desired method change (11.2% Triquilar and 14.1% Marvelon). Method unrelated reasons (unable to return to clinic, moving/travel, and not interested in the study) were the next most common reason for discontinuation. 3 women conceived while taking Triquilar. These pregnancies were attributed to method failure, perhaps due to incomplete pituitary suppression. There were no accidental pregnancies in the Marvelon group.

Matched MeSH terms: Contraceptives, Oral*; Contraceptives, Oral, Combined

Effect of the oral contraceptive pill on protein S and antithrombin-III levels in Malaysian women

Wong KK, Ng SC, Koong PL

Med Sci Res, 1992 Jun;20(12):439-40.

PMID: 12288974

Matched MeSH terms: Contraceptives, Oral*; Contraceptives, Oral, Combined*; Contraceptives, Oral, Hormonal

Fulltext Reproduction research and health: part III: fertility health

Sinnathuray TA

Med J Malaysia, 1980 Mar;34(3):307-13.

PMID: 7412671

The tremendous research advances in recent decades in the three widely used methods of fertility regulation (family planning), namely hormonal steroidal contraception, sterilisation and legal abortion, have been presented and discussed. The considerable health benefits accruing to the woman, in particular, and to the society, in general, from the practice of these fertility regulation methods. especially in the context of developing countries, have been reviewed. Recent research advances in the area of fertility augmentation (infertility management) have been presented and discussed. The manner in which some of the future trends in fertility regulation are likely to develop has been briefly stated.

Matched MeSH terms: Contraceptives, Oral, Hormonal

Effect of combined low-dose oral contraceptives on blood viscosity and haematocrit

Ishak R, Loh Chooi Khim

Malays J Reprod Health, 1991 Jun;9(1):5-8.

PMID: 12317443

Matched MeSH terms: Contraceptives, Oral; Contraceptives, Oral, Combined*; Contraceptives, Oral, Hormonal

Fibrinolytic response in women on low-dose oral contraceptive

Ishak R, Ahmad R, Gudum HR, Hassan K, Ang ES

Malays J Reprod Health, 1992 Jun;10(1):7-11.

PMID: 12345026

PIP: Long term use of low doses of combination oral contraceptives appears to increase plasminogen level, thereby increasing fibrinolytic activity and reducing the risk of thromboembolism. Blood levels of plasminogen, tissue plasminogen activator (tPA), and plasminogen activator inhibitor (PAI), were measured before and after stress (5 minutes of stair climbing) in a group of 30 women, 23-40 years old, who had taken 30 mcg of ethinyl estradiol with 150 mcg of desogestrel or levonorgestrel for at least 1 year. Similar measurements were taken from a control group of 30 women matched for age, height, and weight. Plasminogen and tPA levels in both groups increased significantly after exercise. The level of PAI did not change significantly with stress in either group. The level of plasminogen was significantly higher in the group taking contraceptives, whether before or after exercise, when compared to the control group. Levels of tPA and PAI, although slightly increased in the oral contraceptive group, were not significantly different between the two groups. The increase in plasminogen may be due to the estrogen component of the contraceptives. Stress seems to increase fibrinolytic response.

Matched MeSH terms: Contraceptives, Oral*; Contraceptives, Oral, Combined*

Fulltext Unilateral superior ophthalmic vein thrombosis in a user of oral contraceptives

Jaais F, Habib ZA

Med J Malaysia, 1994 Dec;49(4):416-8.

PMID: 7674980

A patient on oral contraceptives over several years developed unilateral proptosis, haemorrhagic retinopathy and increase in intraocular pressure. An orbital vein venogram confirmed the diagnosis of right superior ophthalmic vein thrombosis. There was complete resolution of thrombosis and eye signs and symptoms with discontinuation of the oral contraceptive.

Matched MeSH terms: Contraceptives, Oral/adverse effects*

Fulltext A preliminary report on the relationship between serum anti-thrombin III concentration in pre- and post-operative patients and in women on oral contraceptives

Ton SH, Lopez CG, Thiruselvam A, Lyou YT

Med J Malaysia, 1981 Dec;36(4):212-4.

PMID: 7334955

A T III values in patients undergoing surgery were found to be lower post-operatively but the fall in value was not significant while women on oral contraceptives were found to have similar AT III values as that of women not on oral contraceptives. The observed values are discussed.

Matched MeSH terms: Contraceptives, Oral/pharmacology*

Fertility control and the risk of gynecological malignancies

Sivanesaratnam V

Obstet Gynecol Surv, 1991 Mar;46(3):131-7.

PMID: 1849623

Matched MeSH terms: Contraceptives, Oral, Hormonal/adverse effects*

Singapore: a study of clinic continuation rates

Kee WF, Tee QS

Stud Fam Plann, 1971 Dec;2(12):257-8.

PMID: 5164393 DOI: 10.2307/1965081

Matched MeSH terms: Contraceptives, Oral*

Role of hormonal fluctuations in temporomandibular disorder pain: facts to ponder

Das S, Rajalingham S

Pain, 2012 Jan;153(1):250-251.

PMID: 22119339 DOI: 10.1016/j.pain.2011.10.039

Matched MeSH terms: Contraceptives, Oral, Hormonal/administration & dosage*

The demand for abortion in an urban Malaysian population

Ooi OS

Med J Malaya, 1971 Mar;25(3):175-81.

PMID: 4253243

Matched MeSH terms: Contraceptives, Oral/adverse effects

Management of bleeding irregularities among etonogestrel implant users: Is combined oral contraceptives pills or nonsteroidal anti-inflammatory drugs the better option?

Upawi SN, Ahmad MF, Abu MA, Ahmad S

J Obstet Gynaecol Res, 2020 Mar;46(3):479-484.

PMID: 31958877 DOI: 10.1111/jog.14195

AIM: This study is to evaluate whether unacceptable bleeding among the etonogestrel implant user could be better alleviated using combined oral contraceptive pills (COCP) or nonsteroidal anti-inflammation drugs (NSAID).

METHODS: This is a prospective randomized study for evaluation of 84 etonogestrel implant (Implanon) users with prolonged or frequent bleeding. They were assigned to either receiving a COCP containing 20 mcg ethinyl estradiol/150 mg desogestrel for two continuous cycle or NSAID; mefenamic acid 500 mg TDS for 5 days, 21 days apart for two cycles. Bleeding pattern during the treatment was recorded and analyzed.

RESULTS: A total of 32 women (76.2%) in COCP group and 15 women (35.7%) in NSAID group stop bleeding within 7 days after the initiation of treatment which was statistically significant (P

Matched MeSH terms: Contraceptives, Oral, Combined/therapeutic use*

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