The Lembah Bujang archeological complex near Sungai Petani, Kedah consists of various structures constructed at different times and spread over a wide area. This paper reports on the thermoluminescence (TL) dating of one of these structures. The structure was found to be 350 ± 90 yrs old. This is very young as compared with other structures that are from the 4th to the 16th centuries. This structure is suspected to be remnant of a Muslim Mosque whereas the other structures were Hindu and Buddist temples.
The recovery of uranium from non-conventional sources has its importance in the security of nuclear fuel supply as well as producing a more value-added product to the contaminated source. In this paper, uranium is recovered both by developing a hydrothermal process as well as using the removal method. Developing hydrothermal process involves using high uranium concentrated starting material such as xenotime and thorium hydroxide waste produced from the monazite cracking process. Oxalate separation enable to produce a better uranium and thorium separation from the yttrium in xenotime as compared to the hydroxide precipitation. Also, a solvent extraction stage was included to separate the uranium from the thorium in the process using thorium hydroxide waste. The removal method involves using selective leaching for minerals with lower uranium content such as zircon. A better removal for uranium and thorium in zircon is achieved when a heat treatment process was done prior to the leaching stage. White zircon mineral was produced after this treatment and its quality meets the requirement for white ceramic opacifier and glaze.
Taman Negara is a famous tourism destination for nature lover in Malaysia. The area is well kept from human activities and disturbances. Since there is no data for human exposure to natural radiation, there is a need to do this study. It will give a baseline data for surface dose and radionuclide concentrations and one can estimate the external hazards index for the visitor to this unexplored area, i.e. UiTM-Perhilitan research station, Kuala Keniam, Taman Negara, Malaysia. The surface dose rate measurements were done in-situ using portable radiation survey meter at the surface and 1 m above the surface. The top soil samples were taken using hand auger up to 15 cm depth at nine locations around research station. Samples were brought back to the UiTM laboratory in Shah Alam, dried, ground to powder form, and sieved using 250 μm sieve. Then the uranium and thorium concentrations were analyzed using Energy Dispersive X-Ray Fluorescence (EDXRF).The mean value for surface dose rates on surface were 0.164 μSv/hr while the mean value for surface dose rates on 1m above the surface were 0.161 μSv/hr. The mean concentration of thorium was 2.62μg/g while the mean concentration of uranium was 0.61μg/g.
MeSH terms: Background Radiation; Fluorescence; Humans; Human Activities; Laboratories; Malaysia; Surveys and Questionnaires; Radioisotopes; Research; Soil; Thorium; Uranium; X-Rays
UV-curable hyperbranched urethane acrylate (HBPUA) from oleic acid of palm oil has been synthesized through a medium aided by p-toluene sulfonic acid as a catalyst. This mixture was then used as the core (HBP) and reacted with palm oil oleic acid to form the hyperbranched polyol (HBP-1). HBPUA was prepared by reacting HBP-1 resin with diisocyanate and hydroxyl-containing acrylate monomer with the presence of 0.1-2 wt% dibutyltin dilaurate as a catalyst. The reaction was confirmed by several analytical data i.e. hydroxyl value (OHV), Fourier Transform infrared (FTIR) spectroscopy, gel permeation chromatography (GPC) and nuclear magnetic resonance (NMR) spectroscopy analyses. The HBPUA was easily curable when subjected to ultraviolet (UV) radiation.
The presence of 226 Ra in water is a great concern in human life since it can cause health risk to a certain extent. In the state of Kelantan, being known of its granitic area, there is a lack measurement of 226 Ra content in river water, since water is the major source of water supply. According to the INTERIM National Water Quality Standards for Malaysia (INWQS), 226 Ra activity concentration in water cannot exceed 0.1 Bq/L. For this reasons, this research was planned to carry out a systematic measurement of water along Sungai Kelantan. Liquid Scintillation Counting was used for measurement of 226 Ra in water samples from Sungai Kelantan mainly in district of Kuala Krai. In this paper, the results obtained is about 26 water samples, filtered and unfiltered, collected along Sungai Lebir, Sungai Sok and Bukit Sabah. Thus, the assessment activity concentration of 226 Ra in river water was obtained as well as annual effective dose for consumption of drinking water.
MeSH terms: Fresh Water; Humans; Malaysia; Scintillation Counting; Water Supply; Rivers; Biological Processes; Physiological Processes; Water Quality; Drinking Water
Over 114 countries in the world grow rice and more than 50 countries have an annual rice production of 100,000 tonnes or more. Asian farmers produce about 90% of the global total rice production. Generally, there are two most common varieties of rice; cultivated and hill rice. Nowadays a lot of agriculture land is contaminated with toxic elements owing to the use of sludge or municipal compost, pesticides, fertilizers and emissions from municipal waste incinerators, car exhausts, residues from metalliferous mines, and smelting industries. The distribution and concentration of several toxic elements in grains particularly rice has lately become a big concern. A study to determine the concentrations of some elements in a few varieties of rice in our local market using Instrumental Neutron Activation Analysis has been performed by Waste and Environmental Technology Division, Malaysian Nuclear Agency. A total of 15 elements were measured. The method was validated by analysing the Standard Reference Material SRM-1568a (Rice Flour) and SRM-1573a (Tomato Leaves) of NIST. The measured concentrations of major and minor elements were analysed in terms of the average intake of nutrient content and comparison of several toxic elements to other studied values.
Since the world’s first nuclear reactor major breakthrough in December 02, 1942, the nuclear power industry has undergone tremendous development and evolution for more than half a century. After surpassing moratorium of nuclear power plant construction caused by catastrophic accidents at Three-Mile Island (1979) and Chernobyl (1986), today, nuclear energy is back on the policy agendas of many states, both developed and developing nations, signaling nuclear revival or nuclear renaissance. Selection of suitable nuclear power technology has thus been subjected to primary attention. This short paper attempts to draw preliminary technology assessment for the first nuclear power reactor technology for Malaysia. Methodology employed is qualitative analysis collating recent finding of TNB-KEPCO Preliminary Feasibility Study for Nuclear Power Program in Peninsular Malaysia and other published presentations and/or papers by multiple experts.
The results suggested that the pressurized water reactor (PWR) is the prevailing technology in terms of numbers and plant performances, and while the commercialization of Gen IV reactors is remote (e.g. not until 2030), Generation III/III+ NPP models are commercially available on the market today. Five (5) major steps involved in reactor technology selection were introduced with a focus on introducing important aspects of selection criteria. Three (3) categories for the of reactor technology selection were used for the cursory evaluation. The outcome of these analyses shall constitute deeper and full review analyses of the recommended reactor technologies for the intended full feasibility study in the near future. Recommendations for reactor technology option were also provided for both strategic and technical recommendations. The paper shall also postulate or rather implore what could be the best way for Malaysian and also other aspiring new entrant nations to select systematically their first civilian nuclear power reactor.
The aim of this study is to design radon irradiation technique in the field of hematology for an invitro study. In addition, deposit of alpha particles into the human blood surface and its effects on the thrombocytopenia estimated using nuclear track detectors (NTDs). In this technique, amount of radon gas (2210±5.1Bq/m 3 ) collected in a tight PVC container with the appropriate engineering dimension using two sources of radium (5μCi). Blood samples (10 male and 10 female) and CR-39NTDs (40 pieces) are exposed to radon gas at various exposure time. Complete blood test and the computer scanning for each piece of CR-39NTDs before and after exposure has done. The results show that the present technique has a good efficiency (96%) to the invitro exposure of human blood. When the radon gas moved on the surface of blood sample, alpha tracks registered into CR-39NTDs. Thus, this technique improved that the comparative method to evaluate alpha particle density into exposure blood samples is an effective way; this depended on the geometry of design and the sensitivity of CR-39NTDs to track registration. Radon detector version 7 (RAD7) used to make a certain suitability of CR- 39NTDs. Amount of radon concentration losses during the exposure process, in the present work it was variable from 0.41% to 1.4%. Radon concentration effected on the thrombocytopenia; this depended on time of exposure and alpha energy loss into the blood and CR-39 through the atomic displacements. At the time of exposure of 10 minutes, rate of absorption dose was 2.255±0.11μSv (39%), and the platelet (PLT) cont reduced rapidly (high effected on reduce PLT, this makes thrombocytopenia.
Objective: To determine the construct validity and the internal consistency of the Postgraduate Stressor Questionnaire (PSQ) among postgraduate medical trainees hence it could be used as a valid and reliable instrument to identify stressors among them.
Methods: Items of the PSQ were derived from a review of literature on the subject and a discussion with experts in the field. It comprised of 28 items with seven hypothetical groups. The content and face validity was established through discussion with experts from field of Medical Education and Psychiatry. It was administered to all participants (N = 34) of postgraduate personal and professional development programme in a Malaysian university. Data was analysed using Statistical Package Social Sciences (SPSS) version 18. Factor analysis was applied to test construct validity whereas reliability analysis was applied to test internal consistency of the PSQ.
Results: Thirty three postgraduate medical trainees participated in this study. Factor analysis found that the 28 items of the PSQ were loaded nicely into the seven pre-determined groups as their factor loading values were more than 0.3. The reliability analysis showed that the Cronbach's alpha value for The PSQ was 0.95. Whereas, The Cronbach's alpha values for academic, poor relationship with superior, bureaucratic constraints, work-family conflicts, poor relationship with colleagues, performance pressure, and poor job prospect domains were 0.63, 0.84, 0.81, 0.65, 0.73, 0.78, and 0.70 respectively.
Conclusion: This study showed that the PSQ is a reliable and valid instrument to identify stressors of postgraduate medical trainees. It is a promising instrument that can be used in future to explore further on this area.
MeSH terms: Education, Medical; Factor Analysis, Statistical; Psychiatry; Surveys and Questionnaires; Social Sciences; Universities; Reproducibility of Results; Family Conflict
Objective: To determine the sensitivity, specificity and internal consistency of the Malay version GHQ-30 among medical student population. This study also determined the level of agreement between GHQ-30 and M-BDI.
Methods: The Malay version GHQ-30 and Malay version Beck Depression Inventory (M-BDI) were administered to 190 medical students. ROC curve analysis was applied to determine the sensitivity and specificity of the GHQ-30 by testing against the M-BDI diagnoses. Reliability and Kappa analysis were applied to test internal consistency of the GHQ and to determine the level of agreement between GHQ-30 and M-BDI respectively.
Results: 141 (74.2%) medical students participated in this study. The GHQ-30 sensitivity and specificity at cut-off point of 5/6 was 87.5% and 80.6% respectively with positive predictive value (PPV) of 70% as well as area under ROC curve was 0.84. The Cronbach’s alpha value of the GHQ-30 was 0.93. The Kappa coefficient was 0.64 (p<0.001).
Conclusion: This study showed the Malay version GHQ-30 is a valid and reliable screening tool in detecting distressed medical students. The GHQ-30 score equal to or more than 6 was considered as significant distress. The GHQ-30 showed a good level of agreement with M-BDI in detecting distressed medical students.
Keywords: Kelantan; Malaysia; medical student
MeSH terms: Depression; Humans; Personality Inventory; Psychiatric Status Rating Scales; ROC Curve; Sensitivity and Specificity; Students, Medical; Universities; Reproducibility of Results
Objective: BigSib Students' Peer-Group Mentoring Programme was implemented as an innovative, interactive and integrated instructional method in the Universiti Sains Malaysia medical school curriculum designed to enhance and strengthen medical students training in soft skills and professional development. This study was conducted to evaluate first- and second-year medical students’ perceptions of and attitudes towards the Programme.
Methodology: A cross sectional study was carried on 314 medical students. Questionnaires assessing medical students' perceptions and attitudes towards the Programme were administered. Data were analysed by using SPSS version 12.
Results: 45.9 % of the students perceived the BigSib Students' Peer-Group Mentoring Programme as successful. More than 50% of the students are willing to participate in the Programme. About 60% of the students perceived it as an effective Programme in developing their soft skills and professionalism.
Conclusion: Medical students have positive attitudes toward the Programme and it is perceived as a successful and effective Programme in developing students' personal attributes. Similar peer-group mentoring programme may be considered relevant to be incorporated into the medical curriculum in the future.
MeSH terms: Professionalism; Attitude; Cross-Sectional Studies; Curriculum; Malaysia; Mentors; Peer Group; Surveys and Questionnaires; Schools, Medical; Students, Medical
Objective: This study aims to report on the process of standard settings (SS) and to compare the passing rates between the norm-reference and SS methods, for OSCE in psychiatry undergraduate examination at UKM for 2009/2010 session. Methods: In the SS method, examiners were asked to imagine the performance of a minimally competent student and gave marks using a standardized check-list. The marks in particular outliers were discussed. After the first round, the examiners went through the same process again, to rate the minimally competent students independently. The median of the marks was taken as the passing mark for the particular question. The passing rate using the passing mark of 50% in the normreference method was compared to the passing rate from the passing mark obtained from the settings method. Results: For question 1, the passing rate with the norm-reference method (i.e. passing mark of 50%) was 93% (106/114) and that by the SS method was 72.8% (83/114). For question 2, the pass rate with the norm-reference method was 92% (105/114) and that by the SS method was 67.5% (77/114). Conclusion: The passing rates between the two methods showed significant differences. Although OSCE is an improvement to the undergraduate psychiatry examination in Universiti Kebangsaan Malaysia, there were few limitations and challenges that need to be tackled for further improvement.
MeSH terms: Educational Measurement; Malaysia; Psychiatry; Students
This paper discusses the evolution of PSR development for people with severe mental illness since the early 20th century in Malaysia. The various aspects of PSR include the activities, service target, the treatment settings, factors contributed to the development and the challenges that have been faced are also described along with the evolution, comparing the past and
present. It is learned that despite of many challenges, PSR in Malaysia has now continued to progress with increasing supports from the stakeholders and is in keeping with the current PSR concept.
MeSH terms: Mental Disorders; Biological Evolution; Face; Learning; Malaysia
Objective: This case report highlights the abuse and dependence potential of Zolpidem and the risk of life-threatening withdrawal symptoms upon abrupt discontinuation. Method: We report a case of Zolpidem dependence which presented with withdrawal symptoms upon abrupt discontinuation. Results: A 32 year old male, who had abused non-benzodiazepine Zolpidem for 6 years presented to the accident and emergency unit with generalized seizures upon stopping Zolpidem ‘cold turkey’. He required admission to the neurology high dependency unit for stabilization of the seizures and was later managed by the addiction team where a tapering dose of benzodiazepine was prescribed. Conclusion: This case demonstrates that non-benzodiazepine agents can cause tolerance and dependence, and thus produce withdrawal symptoms upon discontinuation.
Objective: This case report highlights the risk of Torsade de Pointes (TdP), a life threatening cardiac arrhythmia in a heroin dependent patient receiving methadone substitution therapy who was prescribed erythromycin for upper respiratory tract infection. Method: We report a case of a 35-year-old Malay man on methadone maintenance treatment who developed TdP possibly due to drug interaction between methadone and erythromycin. Results: The
patient reported feeling unwell, chest pain and feeling dizzy after consuming 2 doses of erythromycin. ECG monitoring showed prolonged rate-corrected QT interval leading to TdP. The patient was admitted to the ward where the cardiac arrhythmia ceased following methadone discontinuation. This cardiac arrhythmia was most likely due to drug interaction between methadone and erythromycin (an enzyme inhibitor) which led to an increase in methadone concentration and potentiated the adverse effects. Conclusion: As methadone is a beneficial treatment for heroin dependent patients, the risk of cardiac arrhythmia is of great concern. To avoid complications of drug interaction, patients on methadone therapy should be advised to seek medical assessment before taking other drugs. As TdP is life threatening, it is thus important that physicians and psychiatrists involved in the treatment of
heroin dependent patients on methadone substitution therapy be made aware of this risk.
Objective: This review paper will be discussing on mental health of children and adolescents in Malaysia. Behavioural problems, academic failure and underachievement in school are common reasons for referral of children to the medical services. Epidemiological research has substantiated a possible seriously mismatch between the rates of child mental health problems across a broad spectrum and the number of children actually referred to existing services. These data suggest it is imperative in Malaysia to empirically investigate the present realities in the schools in regard to special education needs and their neglect. Methods: The present preliminary study is based on a literature review of epidemiological features of learning disorders and comorbidities using the Cochran library key word search. Available statistics for learning disorders from the WHO are compared with records for the
year 2007 from the Ministry of Education in Malaysia. Results: Findings of this comparison with international prevalence rates of learning disorders and related diseases show a sizable gap between real existing needs in Malaysia, and their perception. Based on quantitative estimates, the findings suggest that some 1.4 million children in Malaysia have mental health difficulties that interfere with normal functioning and development, but adequate services for intervention are largely not available. Conclusion: The present undersupply of adequate service for children with learning difficulties is aggravated by the lack of systematic developmental screening in early childhood in Malaysia. This status affects the outcomes and development of the general education system in efforts to meet challenges in the new century.
Objective: School bullying in Malaysia is on the rise. While efforts are put together to combat the problem, the psychiatric aspect has been neglected. This is a cross-sectional study aimed to determine the association between the symptoms of ADHD and bully/victim problems among Malaysian sixthgraders attending primary schools in Kuala Lumpur.
Methods: A total of 410 sixth-graders from seven randomly selected schools were assessed with regards to bully/victim problems and ADHD symptoms using self-reported questionnaires. Malaysian Bullying Questionnaire was used to rate bully/victim problems while ADHD symptoms were assessed using ConnersWells’ Adolescent Self-report Scale (CASS). Teachers and parents also assessed students’ ADHD symptoms using Conner’s Teachers Rating Scale (CTRS) and Conner’s Parents Rating Scale (CPRS), respectively.
Results: Self-reported questionnaires showed that 61.2% of the children were involved in bully/victim problems. The ADHD symptoms were found significant in relation to bully/victim problems as tested by multiple logistic regression. Only students and parents reported significant ADHD symptoms among the bully/victim groups. The ADHD symptoms reported by students were significant among bullies(OR=0.59,CI=0.42-0.83, p
MeSH terms: Adolescent; Attention Deficit Disorder with Hyperactivity; Child; Cross-Sectional Studies; Humans; Malaysia; Parents; Surveys and Questionnaires; Schools; Students; Logistic Models; Self Report; Bullying; School Teachers
Objectives: The objective of the study is to determine the prevalence of substance abuse for alcohol, cannabis, opiates, stimulants, solvent and other substances among patients with schizophrenia in Hospital Bahagia Ulu Kinta (HBUK), Perak , Central Peninsular of Malaysia. This study also aims to determine the association of substance abuse with aggression, the demographic characteristics and total duration of hospitalization.
Methods: This was a retrospective cross-sectional study whereby the first 194 subjects diagnosed to have schizophrenia based on International Classification of Disease, 10th edition (ICD-10) criteria were taken from data registry of patients admitted to HBUK from January until February 2004. The subjects’ medical files were examined for documentation of substances abuse, aggression and accumulative duration of hospitalization.
Results: The results showed the prevalence of substances misuse among patients with schizophrenia in general (including alcohol) was 24.7%. Cannabis 16.7%, alcohol 13.4%, opiates(heroin) 6.7%, Amphetamine type stimulants (amphetamine, metamphetamine, ecstacy) 5.7%, and other substances (benzodiazepine, solvents) 1.5%.
Conclusion: There is higher prevalence of substance misuse in patients with schizophrenia as compared to general population. Male patients with history of substance misuse are more likely to have aggression than female. This group needs special precaution and probably in need of specialist help.
MeSH terms: Aggression; Alcohols; Amphetamine; Central Nervous System Stimulants; Benzodiazepines; Cannabis; Cross-Sectional Studies; Heroin; Female; Hospitalization; Hospitals, Psychiatric; Humans; Malaysia; Male; Methamphetamine; Registries; Retrospective Studies; Schizophrenia; Solvents; Prevalence; Substance-Related Disorders; International Classification of Diseases
Objective: Female sexual dysfunction is a known complication of diabetes mellitus. The aims of this study is to estimate the prevalence of sexual dysfunction and the types of sexual dysfunction experienced by Malay women with type 2 diabetes mellitus.
Methods: Cross sectional study was conducted on married Malay women with type 2 diabetes mellitus, receiving treatment from two community clinics in Selangor, Malaysia. Female sexual function was assessed using Malay version of Female Sexual Function Index.
Results: This study found that sexual dysfunction was present among 18.2% women. Lack of libido was the commonest symptom among these women and was observed in 40.9% of women followed by sexual dissatisfaction (36.4%). Sexual arousal disorder was observed in 22.7%, 18.2% complained of lack of lubrication, and 22.7% had vaginal discomfort. Orgasmic dysfunction was found in only 4.5% of these women.
Conclusion: This preliminary research showed sexual desire disorder was the commonest type of sexual disorder among diabetic women.
MeSH terms: Ambulatory Care Facilities; Cross-Sectional Studies; Diabetes Mellitus, Type 2; Female; Humans; Libido; Lubrication; Malaysia; Marriage; Sexual Behavior; Prevalence; Sexual Dysfunctions, Psychological
Objective: Medical training has always been regarded as a highly stressful environment to students. This article described a preliminary data on impact of a stress-management programme on medical students’ stress level. Methods: This is a quasi-experimental before after comparison study design. The programme was run over half-day and convenient sampling method was applied. Sample size as calculated for this preliminary study was 38. The 12 items General Health Questionnaire (GHQ-12) was administered prior to the
programme and four months later. Data was analysed using SPSS version 12. Results: 34 participants were involved in this study. This study found that there was a significant difference in participants’ GHQ-12 scores before and after the programme (p
MeSH terms: Counseling; Humans; Psychotherapy; Surveys and Questionnaires; Research Design; Students, Medical; Sample Size