Browse publications by year: 2012

  1. Wong JE, Poh BK, Nik Shanita S, Izham MM, Chan KQ, Tai MD, et al.
    Singapore Med J, 2012 Nov;53(11):744-9.
    PMID: 23192502
    This study aimed to measure the basal metabolic rate (BMR) of elite athletes and develop a gender specific predictive equation to estimate their energy requirements.
    MeSH terms: Adolescent; Adult; Basal Metabolism*; Body Composition; Body Weight; Calorimetry, Indirect; Energy Metabolism; Female; Humans; Malaysia; Male; Regression Analysis; Sports; Asian Continental Ancestry Group; Young Adult; Athletes*
  2. Lee WS, Chai PF, Ismail Z
    Singapore Med J, 2012 Nov;53(11):755-9.
    PMID: 23192504
    This study aimed to determine the emotional impact on parents of young children who require hospitalisation for acute diarrhoea (AD), and the disruption of daily activities experienced and costs incurred by them.
    MeSH terms: Diarrhea/psychology*; Diarrhea/therapy*; Female; Hospitalization; Humans; Infant; Malaysia; Male; Parents/psychology*; Prospective Studies; Surveys and Questionnaires; Stress, Psychological; Urban Population; Health Care Costs
  3. Kaur S, Rahmat K, Chandran PA, Alli K, Aziz YF
    Singapore Med J, 2012 Nov;53(11):e240-3.
    PMID: 23192514
    The incidence of synchronous bilateral infiltrating breast cancer has been reported to be 2%. However, synchronous unilateral infiltrating ductal carcinoma and infiltrating lobular carcinoma (ILC) are very rarely reported. We present a woman with palpable ILC who was later found to have synchronous well-circumscribed ductal carcinoma on further imaging. We also discuss the use of diagnostic approaches such as ultrasonography, mammography and histopathology. This case highlights the importance of careful assessment of concurrent lesions in the breast in the presence of an existing carcinoma.
    MeSH terms: Breast Neoplasms/complications; Breast Neoplasms/diagnosis*; Female; Humans; Mammography; Middle Aged; Neoplasms, Second Primary/diagnosis; Carcinoma, Ductal, Breast/complications*; Carcinoma, Ductal, Breast/diagnosis*; Carcinoma, Lobular/complications*; Carcinoma, Lobular/diagnosis*
  4. Shanita NS, Norimah AK, Abu Hanifah S
    Malays J Nutr, 2012 Dec;18(3):283-93.
    PMID: 24568069 MyJurnal
    The aim of this study was to develop and validate a semiquantitative food frequency questionnaire (FFQ) for assessing habitual added sugar consumption of adults in the Klang Valley.
    MeSH terms: Adolescent; Adult; Energy Intake; China/ethnology; Cross-Sectional Studies; Diet*; Female; Food*; Food Habits; Humans; India/ethnology; Malaysia/ethnology; Male; Surveys and Questionnaires*; Mental Recall; Diet Records; Body Mass Index; Dietary Sucrose/administration & dosage*; Young Adult
  5. Gan WY, Mohd NM, Siti AH, Zalilah MS
    Malays J Nutr, 2012 Dec;18(3):295-306.
    PMID: 24568070 MyJurnal
    This study aimed to evaluate the validity and reliability of the Multidimensional Body Image Scale (MBIS), a seven-factor, 62-item scale developed for Malaysian female adolescents. This scale was evaluated among male and female Malaysian university students.
    MeSH terms: Adolescent; Feeding and Eating Disorders; Body Image/psychology*; China/ethnology; Cross-Sectional Studies; Diet, Reducing; Female; Humans; India/ethnology; Malaysia/ethnology; Male; Self Concept; Sex Factors; Students/psychology*; Universities*; Reproducibility of Results; Body Mass Index; Young Adult
  6. Roseline YW, Shidoji Y, Hon WM, Masaki M
    Malays J Nutr, 2012 Dec;18(3):307-17.
    PMID: 24568071 MyJurnal
    INTRODUCTION: Gout and hyperuricaemia attributed to genetic and lifestyle factors have been associated with several chronic diseases. This study aimed to determine the association and interaction effects between vascular endothelial growth factor receptor-2 (VEGFR-2) gene polymorphisms (rs1870377 and rs2071559) and dietary patterns on blood uric acid in Malay and Indian adults.
    METHODS: Dietary intakes of 153 Malays and 177 Indians were obtained using a food frequency questionnaire for the construction of dietary patterns using factor analysis. Genotyping of rs1870377 and rs2071559 was performed by real-time PCR using TaqMan probes. Anthropometric measurements, body mass index (BMI) and blood pressure and biomarkers, uric acid, glycated haemoglobin A1c (HbA1c), and blood lipids were determined.
    RESULTS: There were significant differences in the mean values for HbA1c (41±-12 vs 45±-8 mmol/mol, p<0.001) and blood lipids levels (p<0.05) between Malays and Indians. Significant correlations were obtained between uric acid with selected blood lipids (p<0.05) and BMI in Malays (r=0.362, p<0.001) and Indians (r=0.212, p<0.01). Four dietary patterns were extracted from dietary intakes of all subjects: ‘Vegetables diet’; ‘Fruits diet’ (FD); ‘Animal protein and rice diet’; and ‘Fast foods and preserved foods diet’. There were no significant associations between dietary patterns (p=0.054-0.609) and VEGFR-2 gene polymorphisms (p=0.348-0.778) with uric acid. In Malay subjects, the interaction of rs2071559 and FD had a borderline effect (p=0.05) on blood uric acid after adjusting for potential confounders.
    CONCLUSION: The associations and gene-diet interactions involving VEGFR-2 gene polymorphisms and FD on uric acid provide new information on gout and hyperuricaemia risks in Malays.
    Keywords: Gene-diet interaction, VEGFR-2 gene polymorphisms, dietary pattern, uric acid, Malaysians
    MeSH terms: Adult; Animals; Diet*; Dietary Proteins; Female; Food; Fruit; Genotype; Gout/etiology; Gout/genetics; Hemoglobin A, Glycosylated/analysis; Humans; India/ethnology; Lipids/blood; Malaysia; Malaysia/ethnology; Male; Middle Aged; Polymorphism, Genetic*; Surveys and Questionnaires; Uric Acid/blood*; Vegetables; Body Mass Index; Polymorphism, Single Nucleotide/genetics; Hyperuricemia/etiology; Hyperuricemia/genetics; Vascular Endothelial Growth Factor Receptor-2/genetics*; Fast Foods; Real-Time Polymerase Chain Reaction
  7. Lim SH, Fan SH, Say YH
    Malays J Nutr, 2012 Dec;18(3):345-54.
    PMID: 24568075 MyJurnal
    INTRODUCTION: There is a pressing need to better understand the complex biochemical pathways that lead to the pathogenesis of obesity. Increased oxidative stress and decreased antioxidant capacity have been identified to be associated with obesity. Therefore, the objectives of this study were to determine the plasma total antioxidant capacity (TAC) levels of Malaysian subjects and to evaluate its potential association with obesity and related anthropometric measurements.
    METHODS: Plasma TAC of 362 multi-ethnic Malaysian subjects from the Kampar Health Clinic (138 males, 224 females; 124 ethnic Malays, 152 Chinese, 86 Indians; 192 non-obese, 170 obese) was measured using Trolox equivalent antioxidant capacity (TEAC) 96-well plate assay.
    RESULTS: Plasma TAC was significantly lower in obese subjects (M +/- SE = 292 +/- 10.4 micromol/L) compared to non-obese subjects (397 +/- 8.58 micromol/L), whereas it was significantly higher in males and those in the 21-30 age group. Those with salty food preference and practising a strict vegetarian diet also had significantly higher plasma TAC. However, no association was found for other dietary habits (coffee intake) and lifestyle factors (physical activity, smoking). Plasma TAC was also significantly negatively correlated with diastolic blood pressure, waist and hip circumferences, weight, body mass index, total body fat, % subcutaneous fat, visceral fat level, resting metabolism and % skeletal muscle.
    CONCLUSION: Plasma TAC was found to be associated with obesity, strict vegetarian practice, salty food preference and all obesity anthropometric indicators, except systolic blood pressure and pulse rate. Obese people have decreased plasma TAC indicating a compromised systemic antioxidant defence and increased oxidative stress.
    MeSH terms: Adult; Age Factors; Aged; Aged, 80 and over; Ambulatory Care Facilities; Antioxidants/analysis*; Blood Pressure; Body Composition; Body Weight; China/ethnology; Chromans; Cross-Sectional Studies; Ethnic Groups; Female; Food Habits; Humans; India/ethnology; Life Style; Malaysia/ethnology; Male; Middle Aged; Obesity/blood*; Sex Factors; Sodium, Dietary; Diet, Vegetarian; Body Mass Index; Oxidative Stress
  8. Nursakinah I, Zulkhairi HA, Norhafizah M, Hasnah B, Zamree MS, Farrah SI, et al.
    Malays J Nutr, 2012 Dec;18(3):363-71.
    PMID: 24568077 MyJurnal
    The objective of this study was to determine antioxidant potential of Garcinia atroviridis leaves and fruits extracts in vitro.
    MeSH terms: Antioxidants/analysis*; Biphenyl Compounds/chemistry; Ferric Compounds/chemistry; Fruit/chemistry*; Gallic Acid/analysis; Minerals/analysis; Nutritive Value*; Phenols/analysis*; Picrates/chemistry; Plant Extracts/chemistry; Plant Leaves/chemistry*; Garcinia*
  9. Chew SC, Khor GL, Loh SP
    Malays J Nutr, 2012 Dec;18(3):383-91.
    PMID: 24568079 MyJurnal
    Data on folate availability of Malaysian cooked foods would be useful for estimation of dietary folate intake; however such information is scarce.
    MeSH terms: Biological Availability; Chromatography, High Pressure Liquid; Cooking; Folic Acid/analysis*; Folic Acid/pharmacokinetics; Food; Food Analysis*; Hot Temperature*; Humans; Malaysia; Oryza/chemistry
  10. Ng TK, Low CX, Kong JP, Cho YL
    Malays J Nutr, 2012 Dec;18(3):393-7.
    PMID: 24568080 MyJurnal
    Carotenoid-rich red palm oil (RPO)-based snacks have been provided to children in impoverished communities to improve their vitamin A status. The non-availabilty of information on the acceptability of RPO-based snacks by Malaysian aborigines (Orang Asli) children forms the basis of this study.
    MeSH terms: Carotenoids/administration & dosage*; Child Nutritional Physiological Phenomena; Child, Preschool; Diet*; Female; Food; Food Preferences; Humans; Malaysia; Male; Plant Oils/administration & dosage*; Surveys and Questionnaires; Vitamin A/administration & dosage*; Body Mass Index; Snacks*
  11. Manshor N, Rosli H, Ismail NA, Salleh B, Zakaria L
    Trop Life Sci Res, 2012 Dec;23(2):1-15.
    PMID: 24575229 MyJurnal
    Fusarium is a cosmopolitan and highly diversified genus of saprophytic, phytopathogenic and toxigenic fungi. However, the existence and diversity of a few species of Fusarium are restricted to a certain area or climatic condition. The present study was conducted to determine the occurrence and diversity of Fusarium species in tropical highland areas in Malaysia and to compare with those in temperate and subtropical regions. A series of sampling was carried out in 2005 to 2009 at several tropical highland areas in Malaysia that is: Cameron Highlands, Fraser Hills and Genting Highlands in Pahang; Penang Hill in Penang; Gunung Jerai in Kedah; Kundasang and Kinabalu Park in Sabah; Kubah National Park and Begunan Hill in Sarawak. Sampling was done randomly from various hosts and substrates. Isolation of Fusarium isolates was done by using pentachloronitrobenzene (PCNB) agar and 1449 isolates of Fusarium were successfully recovered. Based on morphological characteristics, 20 species of Fusarium were identified. The most prevalent species occurring on the highlands areas was F. solani (66.1%) followed by F. graminearum (8.5%), F. oxysporum (7.8%), F. semitectum (5.7%), F. subglutinans (3.5%) and F. proliferatum (3.4%). Other Fusarium species, namely F. avenaceum, F. camptoceras, F. chlamydosporum, F. compactum, F. crookwellense, F. culmorum, F. decemcellulare, F. equiseti, F. nygamai, F. poae, F. proliferatum, F. sacchari, F. sporotrichioides, F. sterilihyphosum and F. verticillioides accounted for 1% recoveries. The present study was the first report on the occurrences of Fusarium species on highland areas in Malaysia.
  12. Ahmed QN, Hussain PZ, Othman AS
    Trop Life Sci Res, 2012 Dec;23(2):17-25.
    PMID: 24575230
    This study was conducted to examine the variabilities in the chronology of vegetative and reproductive development of weedy rice (Oryza spp.) in comparison with commercial varieties. Data at different growth stages of 14 weedy rice morphotypes and 4 commercial rice varieties were recorded and analysed. Plant height of all weedy rice morphotypes were observed to be significantly higher compared to the commercial varieties at every growth stages; increase in height was between 10-37 cm for weedy rice morphotype, for every 2 weeks. Initial tillering ability at 14 days after planting (DAP) was higher in weedy morphotypes, however all the commercial rice varieties produced significantly higher number of tillers throughout the rest of the vegetative phases. Correlation between plant height and tiller number detected that taller plants produce fewer tillers than shorter plants. Higher leaf area index (LAI) of all weedy morphotypes except PWR01 at early growth stages indicated the vigorous growth of the morphotypes. Weedy rice morphotypes showed a wide range of anthesis and maturity duration. Accessions from the same weedy rice morphotypes were more heterogeneous in the flowering, anthesis and maturity period than the commercial varieties. These traits enables identification of weedy rice morphotypes at their different growth stages in the field.
    MeSH terms: Phenotype; Oryza; Plant Leaves; Plant Weeds
  13. Yin SA, Ismail A, Zulkifli SZ
    Trop Life Sci Res, 2012 Dec;23(2):27-38.
    PMID: 24575231 MyJurnal
    Swamp eel, Monopterus albus is one of the common fish in paddy fields, thus it is suitable to be a bio-monitor for heavy metals pollution studies in paddy fields. This study was conducted to assess heavy metals levels in swamp eels collected from paddy fields in Kelantan, Malaysia. The results showed zinc [Zn (86.40 μg/g dry weight)] was the highest accumulated metal in the kidney, liver, bone, gill, muscle and skin. Among the selected organs, gill had the highest concentrations of lead (Pb), cadmium (Cd) and nickel (Ni) whereas muscle showed the lowest total metal accumulation of Zn, Pb, copper (Cu), Cd and Ni. Based on the Malaysian Food Regulation, the levels of Zn and Cu in edible parts (muscle and skin) were within the safety limits. However, Cd, Pb and Ni exceeded the permissible limits. By comparing with the maximum level intake (MLI), Pb, Ni and Cd in edible parts can still be consumed. This investigation indicated that M. albus from paddy fields of Kelantan are safe for human consumption with little precaution.
  14. Shahrudin S, Jaafar I
    Trop Life Sci Res, 2012 Dec;23(2):49-57.
    PMID: 24575233 MyJurnal
    The study on the amphibian fauna of Bukit Jana, Taiping, Perak was carried out from January 2009 until December 2010 with a total of 12 nights of observation. Twenty four species of frogs from 14 genera and 6 families were recorded to inhabit the Bukit Jana areas. Seven commensal species were found around human habitations near the foothill whereas the others are typical forest frogs found mostly near the rivers, streams and forest floor. This is the first amphibian checklist of Bukit Jana, Perak and it contributed 22% out of 107 species of frogs that are recorded to inhabit Peninsular Malaysia.
    MeSH terms: Animals; Anura; Humans; Malaysia; Ranidae; Rivers; Checklist; Forests
  15. Rosli NA, Isa MM
    Trop Life Sci Res, 2012 Dec;23(2):59-65.
    PMID: 24575234 MyJurnal
    Scanty information exists pertaining to the length-weight relationship (LWR) and length-length relationship (LLR) parameters of longsnouted catfish, Plicofollis argyropleuron in lotic systems throughout the northern part of Peninsular Malaysia. It is vital to reveal these biological properties of P. argyropleuron in Kuala Muda and Merbok estuary for future management and to increase knowledge about this fish stocks. The fish samples were randomly collected in the estuary area of Kuala Muda and Merbok, Kedah for 10 months from March 2009 to December 2009. The values of the exponent b in the LWR equations (W = aL(b) ) were approximately 3, indicating an isometric growth with high correlation coefficient (r(2)). The value of LLR (r(2)>0.9) indicated that they are highly significant and highly correlated. These parameters are essential for evaluating the relative condition of fish and species managements as well as their fisheries and stock assessment.
    MeSH terms: Animals; Biological Phenomena; Body Weight; Catfishes; Fisheries; Malaysia; Estuaries
  16. Roethlisberger M, Wuerstlein R, Majores M, Müller-Stöver I, Seitz HM, Rhiem K, et al.
    Breast care (Basel, Switzerland), 2012 Dec;7(6):487-9.
    PMID: 24715832 DOI: 10.1159/000345471
    BACKGROUND: The term filariasis comprises a group of parasitic infections caused by helminths belonging to different genera in the superfamily Filaroidea. The human parasites occur mainly in tropical and subtropical regions, but filariae are also found in temperate climates, where they can infect wild and domestic animals. Humans are rarely infected by these zoonotic parasites.

    PATIENTS AND METHODS: A 55-year-old patient presented with a new-onset, subcutaneous, non-tender palpable mass in the right axilla. Ultrasonography showed a 1.3-cm, solid, singular encapsulated node. Sonography of the breast on both sides, axilla and lymphatic drainage on the left side, lymphatic drainage on the right side, and mammography on both sides were without pathological findings. The node was excised under local anesthesia as the patient refused minimal invasive biopsy.

    RESULTS: On histopathological examination, the tail of a parasite of the group of filariae was found. The patient revealed that she had stayed in Africa and Malaysia for professional reasons. 6 months before the time of diagnosis, she had also suffered from a fever and poor general condition after a trip abroad. The patient was referred for further treatment to the Institute for Tropical Medicine at the University of Dusseldorf, where a treatment with ivermectin was conducted on the basis of positive staining with antibodies against filariae.

    CONCLUSION: Our case demonstrates the importance of interdisciplinary collaboration between breast center, pathology, and other specialties such as microbiology and tropical medicine.

    MeSH terms: Africa; Anesthesia, Local; Animals; Animals, Domestic; Axilla; Biopsy; Breast; Climate; Drainage; Female; Filariasis; Filarioidea; Humans; Ivermectin; Malaysia; Mammography; Parasites; Staining and Labeling; Tropical Medicine; Ultrasonography
  17. Chin CK, Abdullah A, Sugita-Konishi Y
    PMID: 24786411 DOI: 10.1080/19393210.2012.713028
    Exposure to aflatoxins in the adult Malaysian diet was estimated by analysing aflatoxins in 236 food composites prepared as "ready for consumption". Dietary exposure to aflatoxin B1 (AFB1) ranged from 24.3 to 34.00 ng/kg b.w./day (lower to upper bound), with peanuts being the main contributor. Estimated liver cancer risk from this exposure was 0.61-0.85 cancers/100,000 population/year, contributing 12.4%-17.3% of the liver cancer cases. Excluding AFB1 occurrence data higher than 15 µg/kg reduced exposure by 65%-91% to 2.27-11.99 ng/kg b.w./day, reducing the cancer risk to 0.06-0.30 cancers/100,000 population/year (contributing 1.2%-6.1% liver cancer cases). Reducing further the ML of AFB1 from 15 to 5 µg/kg yielded 3%-7% greater drop in the exposure to 0.47-10.26 ng/kg b.w./day with an estimated risk of 0.01-0.26 cancers/100,000 population/year (0.2%-5.1% liver cancer cases attributed to dietary AFB1). These findings indicate that current MLs are adequate in protecting Malaysians' health.
    MeSH terms: Adult; Diet*; Environmental Exposure/adverse effects; Environmental Exposure/analysis*; Food Contamination/analysis*; Fungi; Humans; Liver Neoplasms/chemically induced*; Malaysia; Risk Factors; Aflatoxin B1/adverse effects; Aflatoxin B1/analysis*; Risk Assessment
  18. Tan TH, Lee BN, Amir Hassan SZ, Ch'ng ES, Hussein Z
    Nucl Med Mol Imaging, 2012 Dec;46(4):300-3.
    PMID: 24900078 DOI: 10.1007/s13139-012-0160-x
    Ectopic thyroid or thyroid ectopia is a rare developmental anomaly with the prevalence of 1 per 100,000-300,000 population. Even rarer, such an anomaly manifests as dual thyroid ectopia. To our best knowledge, only one case has been reported on dual thyroid ectopia with Graves' disease in the English literature. We present here a case of dual thyroid ectopia complicated by Graves' disease, whereby the diagnosis was rendered through judicious use of various diagnostic modalities coupled with a close clinical follow-up. In this case, therapeutic consideration should be personalized with proper informed consent of the patient.
    MeSH terms: Adult; Case Reports; Female; Graves Disease*; Hospitals; Humans; Hyperthyroidism*; Malaysia; Thyroid Gland/abnormalities*
  19. Huck-Soo L, Richardson S
    J Hum Ergol (Tokyo), 2012 Dec;41(1-2):1-16.
    PMID: 25665194 DOI: 10.11183/jhe.41.1
    The two final decades of the 20th century saw a significant increase in ergonomics activity (and resulting publications) in industrially developing countries (IDCs). However, a few ergonomics papers from Singapore, for example, were published in 1969 and 1970. This paper reviews developments in ergonomics in industrially developing countries from 1969 relying heavily on published papers although their quality varies considerably. Some criticism of these papers is offered. Most were concerned with the use of work tools, workstation operations, material handling and working environments especially in tropical climates. The similar problems encountered in a variety of countries are discussed, and the importance of low-cost solutions stressed. This study presents an overview of er gonomics research in IDCs. It concentrates on ASEAN countries whilst recognising the valuable work done in other areas.
    MeSH terms: Asia; Developing Countries; Environmental Health/organization & administration*; Humans; Occupational Health/standards*; Cost Savings; Technology Transfer; Needs Assessment
  20. Gibson RS, Cavalli-Sforza T
    Food Nutr Bull, 2012 Sep;33(3 Suppl):S214-20.
    PMID: 23193773
    Collection of nationwide food consumption data at the individual level is the preferred option for planning fortification programs. However, such data are seldom collected in low-income countries. In contrast, Food Balance Sheets (FBS), published annually for approximately 180 countries, may provide a source of national data for program planning.
    MeSH terms: Adolescent; Asia, Southeastern; Energy Intake*; Child; Child, Preschool; Diet; Diet Surveys*; Energy Metabolism*; Family Characteristics; Female; Food Habits; Food Supply; Food, Fortified*; Humans; Male; Pacific Islands; Poverty; Nutrition Policy; Micronutrients/administration & dosage; Micronutrients/deficiency*; Young Adult
External Links