Affiliations 

  • 1 Department of Medicine and Therapeutics, Faculty of Medicine, The Chinese University of Hong Kong (CUHK), Hong Kong Special Administrative Region; Asia Diabetes Foundation, Hong Kong Special Administrative Region; Department of Medicine, Faculty of Medicine, University of Malaya, Kuala Lumpur, Malaysia
  • 2 Asia Diabetes Foundation, Hong Kong Special Administrative Region
  • 3 Department of Medicine and Therapeutics, Faculty of Medicine, The Chinese University of Hong Kong (CUHK), Hong Kong Special Administrative Region
  • 4 Department of Medicine and Therapeutics, Faculty of Medicine, The Chinese University of Hong Kong (CUHK), Hong Kong Special Administrative Region; Li Ka Shing Institute of Health Sciences, Faculty of Medicine, CUHK, Hong Kong Special Administrative Region
  • 5 Department of Medicine and Therapeutics, Faculty of Medicine, The Chinese University of Hong Kong (CUHK), Hong Kong Special Administrative Region; Asia Diabetes Foundation, Hong Kong Special Administrative Region; Li Ka Shing Institute of Health Sciences, Faculty of Medicine, CUHK, Hong Kong Special Administrative Region
  • 6 Department of Medicine and Therapeutics, Faculty of Medicine, The Chinese University of Hong Kong (CUHK), Hong Kong Special Administrative Region; Li Ka Shing Institute of Health Sciences, Faculty of Medicine, CUHK, Hong Kong Special Administrative Region. Electronic address: alicekong@cuhk.edu.hk
Diabetes Res Clin Pract, 2022 Dec;194:110138.
PMID: 36328212 DOI: 10.1016/j.diabres.2022.110138

Abstract

OBJECTIVE: To evaluate the effect of a team-based multi-component intervention care (MIC) program in obese patients with type 2 diabetes (T2D) and poor glycemic control.

METHODS: Patients with T2D and HbA1c ≥ 8 % and body mass index (BMI) ≥ 27 kg/m2 and/or waist circumference ≥ 80 cm in women and ≥90 cm in men were recruited. The intervention in Diabetes Centre included 1) nurse-led, group-based workshops; 2) review by endocrinologists; 3) telephone reminders by healthcare assistants and 4) peer support during visits. The usual care (UC) group received consultations at outpatient clinic without workshops or peer support. The MIC group received UC after 1-year of intervention. The primary outcome was change of HbA1c from baseline at 1- and 3-year.

RESULTS: Of 207 eligible patients [age (mean ± standard deviation): 56.9 ± 8.8 years, 47.4 % men, disease duration: 13.5 ± 8.2 years, HbA1c: 9.6 ± 1.3 %, BMI: 28.8 ± 4.3 kg/m2, waist circumference: 101.5 ± 9.9 cm (men), 95.3 ± 9.8 cm (women)], 104 received MIC and 103 received UC. 95 % patients had repeat assessments at 1- and 3-year. After adjustment for confounders, MIC had greater HbA1c reduction (β -0.51, 95 % confidence interval [CI] -1.00 to -0.01; P = 0.045) than UC at 1-year, with sustained improvement at 3-year (β -0.56, CI -1.10 to -0.02; P = 0.044).

CONCLUSION: Team-based MIC for 1 year improved glycemic control in obese T2D which was sustained at 3-year.

* Title and MeSH Headings from MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.

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