Hospital Mortality and Adverse Events Following Repair of Congenital Heart Defects in Developing Countries

Bateson BP 1 , Deng L 2 , Ange B 1 , Austin E 3 , Dabal R 2 , Broser T 4 Show all authors , Pennington J 4 , Sivakumar S 5 , Lee C 6 , Truong NLT 7 , Jacobs JP 8 , Cervantes J 9 , Kirklin JK 4 , St Louis J 1

Affiliations 

  • 1 Department of Surgery, Augusta University, Augusta, GA, USA
  • 2 Department of Surgery, University of Alabama at Birmingham, Birmingham, AL, USA
  • 3 Department of Cardiovascular and Thoracic Surgery, University of Louisville, Louisville, KY, USA
  • 4 Kirklin Solutions Inc. Birmingham, AL, USA
  • 5 Department of Cardiothoracic Surgery, National Heart Institute, Kuala Lumpur, Malaysia
  • 6 Department of Thoracic and Cardiovascular Surgery, Seoul St.Mary's Hospital, Seoul, Republic of Korea
  • 7 Department of Cardiovascular Surgery, National Children Hospital, Hanoi, Vietnam
  • 8 Department of Surgery, University of Florida, Gainesville, FL, USA
  • 9 Department of Surgery, Instituto Nacional de Cardiologia, Mexico City, Mexico
World J Pediatr Congenit Heart Surg, 2023 Nov;14(6):701-707.
PMID: 37386780 DOI: 10.1177/21501351231176189

Abstract

BACKGROUND: Mortality associated with the correction of congenital heart disease has decreased to approximately 2% in developed countries and major adverse events are uncommon. Outcomes in developing countries are less well defined. The World Database for Pediatric and Congenital Heart Surgery was utilized to compare mortality and adverse events in developed and developing countries.

METHODS: A total of 16,040 primary procedures were identified over a two-year period. Centers that submitted procedures were dichotomized to low/middle income (LMI) and high income (HI) by the Gross National Income per capita categorization. Mortality was defined as any death following the primary procedure to discharge or 90 days inpatient. Multiple logistic regression models were utilized to identify independent predictors of mortality.

RESULTS: Of the total number of procedures analyzed, 83% (n  =  13,294) were from LMI centers. Among all centers, the mean age at operation was 2.2 years, with 36% (n  =  5,743) less than six months; 85% (n  =  11,307) of procedures were STAT I/II for LMI centers compared with 77% (n = 2127) for HI centers (P 

* Title and MeSH Headings from MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.

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