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Microfluidic systems and ultrasonics for emulsion-based biopolymers: A comprehensive review of techniques, challenges, and future directions

Yu LJ 1 , Koh KS 2 , Tarawneh MA 3 , Tan MC 4 , Guo Y 5 , Wang J 6 Show all authors , Ren Y 7

Affiliations 

  • 1 Faculty of Engineering, Technology and Built Environment, UCSI University 56100 Kuala Lumpur, Malaysia; UCSI-Cheras Low Carbon Innovation Hub Research Consortium 56100 Kuala Lumpur, Malaysia. Electronic address: yulj@ucsiuniversity.edu.my
  • 2 School of Engineering and Physical Sciences, Heriot-Watt University Malaysia, Putrajaya 62200 Malaysia. Electronic address: k.koh@hw.ac.uk
  • 3 Department of Physics, College of Science, Al-Hussein Bin Talal University, P.O. Box 20, Ma'an, Jordan
  • 4 School of Energy and Chemical Engineering, Xiamen University Malaysia, Selangor Darul Ehsan 43900 Sepang, Malaysia. Electronic address: meiching.tan@xmu.edu.my
  • 5 Department of Mechanical, Materials and Manufacturing Engineering, University of Nottingham Ningbo China, Ningbo, China; Research Group for Fluids and Thermal Engineering, University of Nottingham Ningbo China, Ningbo, China. Electronic address: yanhong.guo@nottingham.edu.cn
  • 6 Nottingham Ningbo China Beacons of Excellence Research and Innovation Institute, University of Nottingham Ningbo China, Ningbo, China; Department of Electrical and Electronic Engineering, University of Nottingham Ningbo China, Ningbo, China. Electronic address: jing.wang@nottingham.edu.cn
  • 7 Department of Mechanical, Materials and Manufacturing Engineering, University of Nottingham Ningbo China, Ningbo, China; Research Group for Fluids and Thermal Engineering, University of Nottingham Ningbo China, Ningbo, China; Nottingham Ningbo China Beacons of Excellence Research and Innovation Institute, University of Nottingham Ningbo China, Ningbo, China; Key Laboratory of Carbonaceous Wastes Processing and Process Intensification Research of Zhejiang Province, University of Nottingham Ningbo China, Ningbo, China. Electronic address: yong.ren@nottingham.edu.cn
Ultrason Sonochem, 2024 Dec 31;114:107217.
PMID: 39952167 DOI: 10.1016/j.ultsonch.2024.107217

Abstract

Over the past decade, the advancement of microfluidic technology associated with ultrasonics had received a considerate impact across the field, especially in biomedical and polymer synthesis applications. Nevertheless, there are much hindrance remained unsolved, to achieve simple processing, high scalability and high yield biopolymer products that stabilize during the process. In this review, we discuss the underlying physics for both microfluidic and ultrasonic integration in the synthesis of emulsion-based biopolymer and application. The current progress was outlined, focus on its related applications. We also summarized the current strengths and weakness of the microfluidic-ultrasonic integrated technology, aiming to contribute into SDG 12 for responsible consumption and production.

* Title and MeSH Headings from MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.

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