Affiliations 

  • 1 Department of Pharmacy, School of Medical and Allied Sciences, Galgotias University, Greater Noida, U.P., India
  • 2 School of Pharmacy, KPJ Healthcare University College, Nilai, Malaysia
  • 3 Department of Clinical Laboratory Sciences, College of Applied Medical Science, King Khalid University, Abha, Saudi Arabia
  • 4 School of Pharmacy, Graphic Era Hill University, Dehradun, India
  • 5 Department of Law, Sharda University, Greater Noida, U.P., India
Curr Protein Pept Sci, 2025;26(3):185-200.
PMID: 39350425 DOI: 10.2174/0113892037323136240910052119

Abstract

One of the most well-known instances of an interdisciplinary subject is tissue engineering, where experts from many backgrounds collaborate to address important health issues and improve people's quality of life. Many researchers are interested in using chitosan and its derivatives as an alternative to fabricating scaffold engineering and skin grafts in tissue because of its natural abundance, affordability, biodegradability, biocompatibility, and wound healing properties. Nanomaterials based on peptides can provide cells with the essential biological cues required to promote cellular adhesion and are easily fabricated. Due to such worthy properties of chitosan and peptide, they find their application in tissue engineering and regeneration processes. The implementation of hybrids of chitosan and peptide is increasing in the field of tissue engineering and scaffolding for improved cellular adherence and bioactivity. This review covers the individual applications of peptide and chitosan in tissue engineering and further discusses the role of their conjugates in the same. Here, the recent findings are also discussed, along with studies involving the use of these hybrids in tissue engineering applications.

* Title and MeSH Headings from MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.