Lumusidines A-D and villalstonidine F, macroline-macroline and macroline-pleiocarpamine bisindole alkaloids from Alstonia macrophylla

Lim SH 1 , Low YY , Subramaniam G , Abdullah Z , Thomas NF , Kam TS

Affiliations 

  • 1 Department of Chemistry, University of Malaya, 50603 Kuala Lumpur, Malaysia
Phytochemistry, 2013 Mar;87:148-56.
PMID: 23200029 DOI: 10.1016/j.phytochem.2012.11.005

Abstract

Lumusidines A-D, bisindole alkaloids of the macroline-macroline type, and one of the macroline-pleiocarpamine type, villalstonidine F, were isolated from the stem-bark extract of Alstonia macrophylla (Apocynaceae). The structures and absolute configurations of these alkaloids were established using NMR, MS, and X-ray diffraction analyses.

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