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Deterioration of left ventricular systolic function in extended Pacing to Avoid Cardiac Enlargement (PACE) trial: the predictive value of early systolic dyssynchrony

Fang F 1 , Luo XX 1 , Zhang Q 2 , Azlan H 3 , Razali O 3 , Ma Z 4 Show all authors , Gan SF 5 , Xie JM 1 , Yu CM 6

Affiliations 

  • 1 Division of Cardiology, Department of Medicine and Therapeutics, Institute of Vascular Medicine, Institute of Innovative Medicine, Heart Education And Research Training (HEART) Center, and Li Ka Shing Institute of Health Sciences, Prince of Wales Hospital, The Chinese University of Hong Kong, Shatin, N.T., Hong Kong SAR
  • 2 Department of Cardiology, West China Hospital, Sichuan University, Chengdu, China
  • 3 Department of Cardiology, National Heart Institute, Kuala Lumpur, Malaysia
  • 4 Department of Cardiology, Beijing Jishuitan Hospital, Peking University, Beijing, China
  • 5 Department of Ultrasound, Xiamen Zhongshan Hospital, Xiamen, China
  • 6 Division of Cardiology, Department of Medicine and Therapeutics, Institute of Vascular Medicine, Institute of Innovative Medicine, Heart Education And Research Training (HEART) Center, and Li Ka Shing Institute of Health Sciences, Prince of Wales Hospital, The Chinese University of Hong Kong, Shatin, N.T., Hong Kong SAR professorcmyu@gmail.com
Europace, 2015 Oct;17 Suppl 2:ii47-53.
PMID: 26842115 DOI: 10.1093/europace/euv130

Abstract

Biventricular (BiV) pacing was superior to right ventricular apical (RVA) pacing at extended follow-up in the Pacing to Avoid Cardiac Enlargement (PACE) trial. Early pacing-induced systolic dyssynchrony (DYS) might be related to mid-term result. However, it remains unknown whether early pacing-induced DYS can predict long-term reduction of left ventricular (LV) systolic function.

* Title and MeSH Headings from MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.

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