Affiliations 

  • 1 Institut Pediatrik, Hospital Kuala Lumpur
  • 2 Paediatric Department, Hospital Umum Kuching, Sarawak
  • 3 Paediatric Unit, Universiti Putra Malaysia, Kuala Lumpur, Malaysia
Med J Malaysia, 2009 Dec;64(4):325-6.
PMID: 20954561 MyJurnal

Abstract

We describe a 5 1/2 year old boy who was diagnosed with mild autosomal recessive osteopetrosis based on the presence of bony sclerosis, extramedullary haematopoeisis, leukoerythroblastosis and visual impairment who had an allogeneic bone marrow transplant from a matched sibling donor. Conditioning regime was busulphan 16 mg/kg and cyclophosphamide 200 mg/kg. Apart from transient hypercalcaemia, there were no major post transplant complications. Four years post transplant, the extramedullary haematopoeisis has resolved completely with normal blood counts. Apart from a fracture after a trivial fall two months after transplant, he has not suffered any fracture related limb deformities.

* Title and MeSH Headings from MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.