Leucoridines A-D, cytotoxic Strychnos-Strychnos bisindole alkaloids from Leuconotis

Gan CY 1 , Etoh T , Hayashi M , Komiyama K , Kam TS

Affiliations 

  • 1 Department of Chemistry, University of Malaya, 50603 Kuala Lumpur, Malaysia
J Nat Prod, 2010 Jun 25;73(6):1107-11.
PMID: 20515042 DOI: 10.1021/np1001187

Abstract

Four new bisindole alkaloids of the Strychnos-Strychnos type, leucoridines A-D (1-4), were isolated from the stem-bark extract of Leuconotis griffithii. Alkaloids 1-4 showed moderate cytotoxicity against drug-sensitive and vincristine-resistant human KB cells.

* Title and MeSH Headings from MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.

MeSH terms
Similar publications