Affiliations 

  • 1 S Subramaniam, MS (ORL). Department of Otorhinolaryngology, Faculty of Medicine and Health Sciences, University Putra Malaysia, Serdang
  • 2 A H R Abduallah, MCh. Department of Otorhinolaryngolgy, Hospital Kuala Lumpur
  • 3 I Hairuzah, MPath. Department of Pathology, Faculty of Medicine and Health Sciences, University Putra Malaysia, 43400 Serdang
Med J Malaysia, 2005 Aug;60(3):386-8.
PMID: 16379201

Abstract

Primary histoplasmosis of the larynx is not a common disease. Most cases of laryngeal histoplasmosis results from hematogenous spread of disseminated histoplasmosis usually originating from pulmonary infection by Histoplasma capsulatum. We report a 52-year-old male chronic smoker who had prolonged hoarseness and was initially diagnosed with laryngeal carcinoma. However, biopsy of the laryngeal mucosa confirmed the diagnosis of histoplasmosis. There were no signs of pulmonary or systemic involvement. Treatment with intravenous amphotericin B was given for a week and oral ketaconazole was given for a month with complete resolution of symptoms.

* Title and MeSH Headings from MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.