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A retrospective review comparing the use of Gonal-F and Metrodin-HP for in-vitro fertilisation (IVF)

Lee C 1 , Mak FS 2 , Keith J 3 , Welsh D 4 , Yapp P 4 , Chin R 5

Affiliations 

  • 1 Colin Lee, MRCOG. Damansara Fertility Centre, 55 Jalan SS21/56B, Damansara Utama, Petaling Jaya, Selangor
  • 2 F S Mak, MRCOG. Damansara Fertility Centre, 55 Jalan SS21/56B, Damansara Utama, Petaling Jaya, Selangor
  • 3 J Keith, PhD. Damansara Fertility Centre, 55 Jalan SS21/56B, Damansara Utama, Petaling Jaya, Selangor
  • 4 Damansara Fertility Centre, 55 Jalan SS21/56B, Damansara Utama, Petaling Jaya, Selangor
  • 5 Rachel Chin, MCE. Damansara Fertility Centre, 55 Jalan SS21/56B, Damansara Utama, Petaling Jaya, Selangor
Med J Malaysia, 2003 Mar;58(1):94-8.
PMID: 14556331

Abstract

All cycles of IVF with pituitary down-regulation (n = 57) done at the Damansara Fertility Centre in the year 2000 were studied. All the 57 patients had controlled ovarian hyperstimulation, either using Metrodin HP (n = 27) or Gonal-F (n = 30). Of these, 53 patients reached oocyte pick-up, 26 patients in Metrodin HP group and 27 patients in Gonal-F group. Gonal-F resulted in a higher clinical pregnancy rate of 66.6% compared to Metrodin HP 38.5% (p < 0.05). The live birth rate tends to be higher in Gonal-F group (40.7%) compared to Metrodin HP (30.8%), (p > 0.05).

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