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Neutron Activated Samarium-153 Microparticles for Transarterial Radioembolization of Liver Tumour with Post-Procedure Imaging Capabilities

Hashikin NA 1 , Yeong CH 1 , Abdullah BJ 1 , Ng KH 1 , Chung LY 2 , Dahalan R 3 Show all authors , Perkins AC 4

Affiliations 

  • 1 University of Malaya Research Imaging Centre, Faculty of Medicine, University of Malaya, Kuala Lumpur, Malaysia; Department of Biomedical Imaging, Faculty of Medicine, University of Malaya, Kuala Lumpur, Malaysia
  • 2 Department of Pharmacy, Faculty of Medicine, University of Malaya, Kuala Lumpur, Malaysia
  • 3 Medical Technology Division, Malaysian Nuclear Agency, Kajang, Selangor, Malaysia
  • 4 Radiological and Imaging Sciences, Medical Physics and Clinical Engineering, Medical School, University of Nottingham, Nottingham, United Kingdom
PLoS One, 2015;10(9):e0138106.
PMID: 26382059 DOI: 10.1371/journal.pone.0138106

Abstract

Samarium-153 (153Sm) styrene divinylbenzene microparticles were developed as a surrogate for Yttrium-90 (90Y) microspheres in liver radioembolization therapy. Unlike the pure beta emitter 90Y, 153Sm possess both therapeutic beta and diagnostic gamma radiations, making it possible for post-procedure imaging following therapy.

* Title and MeSH Headings from MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.

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