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Population expansion and gene flow in Giardia duodenalis as revealed by triosephosphate isomerase gene

Choy SH 1 , Mahdy MA 2 , Al-Mekhlafi HM 3 , Low VL 4 , Surin J 5

Affiliations 

  • 1 Department of Parasitology, Faculty of Medicine, University of Malaya, 50603, Kuala Lumpur, Malaysia. seow33huey@gmail.com
  • 2 Department of Parasitology, Faculty of Medicine and Health Science, Sana'a University, Sana'a, Yemen. alsharaby9@yahoo.com
  • 3 Department of Parasitology, Faculty of Medicine, University of Malaya, 50603, Kuala Lumpur, Malaysia. halmekhlafi@yahoo.com
  • 4 Institute of Biological Sciences, Faculty of Science, University of Malaya, 50603, Kuala Lumpur, Malaysia. lucaslow24@gmail.com
  • 5 Department of Parasitology, Faculty of Medicine, University of Malaya, 50603, Kuala Lumpur, Malaysia. joharis@ummc.edu.my
Parasit Vectors, 2015;8:454.
PMID: 26373536 DOI: 10.1186/s13071-015-1084-y

Abstract

Giardia duodenalis is a protozoan parasite that can cause significant diarrhoeal diseases. Knowledge of population genetics is a prerequisite for ascertaining the invasion patterns of this parasite. In order to infer evolutionary patterns that could not be uncovered based on the morphological features, a population genetic study with the incorporation of molecular marker was carried out to access the genetic structure of G. duodenalis isolated from the Malaysian population and the global populations.

* Title and MeSH Headings from MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.

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