Affiliations 

  • 1 Faculty of Medicine, Taibah University, Almadinah Almunawwarah, Kingdom of Saudi Arabia. Electronic address: consultprofsheikh@gmail.com
  • 2 Department of Pharmacology, Faculty of Pharmacy, Lincoln University College, 47301 Petaling Jaya, Selangor Darul Ehsan, Malaysia; Department of Pharmacy, State University of Bangladesh, 77 Satmasjid Road, Dhanmondi, Dhaka 1205, Bangladesh. Electronic address: moklesur2002@yahoo.com
  • 3 Department of Pharmacology, Faculty of Pharmacy, Lincoln University College, 47301 Petaling Jaya, Selangor Darul Ehsan, Malaysia; Biochemistry Program, Institute of Biological Sciences, Faculty of Science, University of Malaya, 50603 Kuala Lumpur, Malaysia
  • 4 Department of Nutrition and Dietetics, Faculty of Medicine and Health Sciences, Universiti Putra Malaysia, 43400 UPM, Serdang, Selangor, Malaysia
Biomed Pharmacother, 2017 Nov;95:614-648.
PMID: 28888208 DOI: 10.1016/j.biopha.2017.08.043

Abstract

Amounting scientific evidences have revealed the antitumor, antimetastatic, antiangiogenic, antiproliferative, chemopreventive and neo-adjuvant efficacy of Prophetic Medicine in various in vitro, in vivo and clinical cancer models. Prophetic Medicine includes plants, dietary materials or spices that were used as remedy recipes and nutrition by the great Prophet Mohammed (peace be upon him) to treat various ailments. Prophetic medicine is the total authentic Hadith narrated by the Prophet (PBUH) in relation to medicine, whether Qur'anic verses or honourable Prophetic Hadith. The ability of functional foods from Prophetic Medicine to modulate various signalling pathways and multidrug resistance conferring proteins with low side-effects exemplify their great potential as neo-adjuvants and/or chemotherapeutics. The present review aims to provide the collective in vitro, in vivo, clinical and epidemiology information of Prophetic Medicines, and their bioactive constituents and molecular mechanisms as potential functional foods for the management of cancer.

* Title and MeSH Headings from MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.