Affiliations 

  • 1 1] James H. Clark Center, Stanford University, Stanford, California, USA. [2] Howard Hughes Medical Institute, Stanford University, Stanford, California, USA. [3] CNC Program, Stanford University, Stanford, California, USA
  • 2 1] James H. Clark Center, Stanford University, Stanford, California, USA. [2] Centre for Intelligent Signal and Imaging Research, Universiti Teknologi Petronas, Perak, Malaysia
  • 3 James H. Clark Center, Stanford University, Stanford, California, USA
  • 4 1] James H. Clark Center, Stanford University, Stanford, California, USA. [2] CNC Program, Stanford University, Stanford, California, USA
Nat. Methods, 2015 Jul;12(7):657-60.
PMID: 26005812 DOI: 10.1038/nmeth.3410

Abstract

We present a robot that enables high-content studies of alert adult Drosophila by combining operations including gentle picking; translations and rotations; characterizations of fly phenotypes and behaviors; microdissection; or release. To illustrate, we assessed fly morphology, tracked odor-evoked locomotion, sorted flies by sex, and dissected the cuticle to image neural activity. The robot's tireless capacity for precise manipulations enables a scalable platform for screening flies' complex attributes and behavioral patterns.

* Title and MeSH Headings from MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.