Affiliations 

  • 1 Department of Nephrology, Serdang Hospital, Selangor, Malaysia
  • 2 Department of Medicine, Bintulu Hospital, Sarawak, Malaysia
Saudi J Kidney Dis Transpl, 2018 2 20;29(1):207-209.
PMID: 29456232 DOI: 10.4103/1319-2442.225177

Abstract

Tranexamic acid (TXA) is an antifibrinolytic agent commonly used to achieve hemostasis. However, there have been a few case reports suggesting that high-dose intravenous TXA has epileptogenic property. In patients with renal impairment, even administering the usual recommended dose of TXA can induce seizure episodes. We present here a patient on hemodialysis who developed seizures after receiving two doses of TXA over 5 h period.

* Title and MeSH Headings from MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.