Affiliations 

  • 1 Department of Physiology, Melaka Manipal Medical College (Manipal Campus), Manipal University , Manipal 576104 , India
Acta. Biol. Hung., 2018 Dec;69(4):371-384.
PMID: 30587025 DOI: 10.1556/018.69.2018.4.1

Abstract

In the behavioral science field, many of the oldest tests have still most frequently been used almost in the same way for decades. The subjective influence of human observer and the large inter-observer and interlab differences are substantial among these tests. This necessitates the possibility of using technological innovations for behavioral science to obtain new parameters, results and insights as well. The light-dark box (LDB) test is a characteristic tool used to assess anxiety in rodents. A complete behavioral analysis (including both anxiety and locomotion parameters) is not possible by performing traditional LDB test protocol, as it lacks the usage of a real-time video recording of the test. In the current report, we describe an improved approach to conduct LDB test using a real-time video tracking system.

* Title and MeSH Headings from MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.