Affiliations 

  • 1 1Metabolomics Laboratory, Biotechnology Centre, Malaysian Agriculture Research and Development Institute (MARDI), Serdang, Selangor Malaysia
  • 2 2China-ASEAN College of Marine Sciences, Xiamen University Malaysia, Sepang, Selangor Malaysia
  • 3 Advanced Chemistry Solutions, Damansara Perdana, Petaling Jaya, Selangor Malaysia
BMC Chem, 2019 Dec;13(1):134.
PMID: 31891160 DOI: 10.1186/s13065-019-0653-0

Abstract

Background: Safety, environmental and economic setbacks are driving industries to find greener approaches to extract bioactive compounds from natural resources. Pressurized hot water extraction (PHWE) is among the solvent free and efficient methods for extracting bioactive compounds.

Experimental: In this study, the suitability of PHWE for extracting bioactive compounds such as phenolics, hydrolysable tannins and flavonoids from Phyllanthus tenellus was investigated by UPLC-qTOF-MS.

Results: Solvent properties of water are significantly increased through imposing temperature at 121 °C and pressure at 15 p.s.i. Pressurized hot water extraction obtained 991-folds higher hydrolysable tannins than methanol extraction.

Conclusion: The extraction yields of hydrolysable tannins with PHWE was almost double of absolute methanol extraction.

* Title and MeSH Headings from MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.