Affiliations 

  • 1 NYU Langone Health, NYU Langone Orthopedic Hospital, New York, New York, USA
  • 2 Hospital Kuala Lumpur, Malaysia
  • 3 Department of Orthopaedic Surgery, School of Medicine, Teikyo University, Tokyo, Japan
  • 4 Liverpool Football Club, Liverpool, UK
Am J Sports Med, 2021 02;49(2):529-537.
PMID: 32427520 DOI: 10.1177/0363546520916729

Abstract

BACKGROUND: Hamstring injuries are common and account for considerable time lost to play in athletes. Platelet-rich plasma has potential as a means to accelerate healing of these injuries.

PURPOSE: (1) To present the evidence of platelet-rich plasma injection in the treatment of hamstring injuries, (2) evaluate the "best-case scenario" in dichotomous outcomes, and (3) evaluate the "worst-case scenario" in dichotomous outcomes.

STUDY DESIGN: Systematic review and meta-analysis.

METHODS: Two authors systematically reviewed the PubMed, Embase, and Cochrane Library databases according to the PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-Analyses) guidelines, with any discrepancies resolved by mutual consensus. The level of evidence was assessed per the criteria of the Oxford Centre for Evidence-Based Medicine and the quality of evidence by the Coleman Methodology Score. Meta-analysis by fixed effects models was used if heterogeneity was low (I2 < 25%) and random effects models if heterogeneity was moderate to high (I2≥ 25%). P values

* Title and MeSH Headings from MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.