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An international retrospective study for tolerability of 6-mercaptopurine on NUDT15 bi-allelic variants in children with acute lymphoblastic leukemia

Tanaka Y 1 , Yeoh AEJ 2 , Moriyama T 3 , Li CK 4 , Kudo K 5 , Arakawa Y 6 Show all authors , Buaboonnam J 7 , Zhang H 8 , Liu HC 9 , Ariffin H 10 , Chen Z 2 , Kham SKY 2 , Nishii R 3 , Hasegawa D 11 , Fujimura J 12 , Keino D 13 , Kondoh K 13 , Sato A 14 , Ueda T 15 , Yamamoto M 16 , Taneyama Y 17 , Hino M 18 , Takagi M 19 , Ohara A 20 , Ito E 5 , Koh K 7 , Hori H 21 , Manabe A 22 , Yang JJ 3 , Kato M 23

Affiliations 

  • 1 Division of Medicinal Safety Science, National Institute of Health Sciences, Kawasaki
  • 2 VIVA-NUS Centre of Translational Research in Acute Leukaemia (Molecular), Department of Pediatrics, Yong Loo Lin School of Medicine, National University of Singapore
  • 3 Department of Pharmaceutical Sciences, St. Jude Children's Research Hospital, Memphis, TN
  • 4 Hong Kong Children's Hospital, The Chinese University of Hong Kong, Shatin, Hong Kong, Special Administrative Region
  • 5 Department of Pediatrics, Hirosaki University Graduate School of Medicine, Hirosaki
  • 6 Department of Hematology/Oncology, Saitama Children's Medical Center, Saitama
  • 7 Hematology/Oncology Division, Department of Pediatrics Faculty of Medicine, Siriraj Hospital Mahidol University
  • 8 Department of Hematology and Oncology, Guangzhou Women and Children's Medical Center
  • 9 Division of Pediatric Hematology-Oncology, Mackay Children's Hospital and Mackay Memorial Hospital, Taipei
  • 10 Department of Paediatrics, University of Malaya Medical Centre, Kuala Lumpur
  • 11 Department of Pediatrics, St. Luke's International Hospital, Tokyo
  • 12 Department of Pediatrics, Juntendo University, School of Medicine, Tokyo
  • 13 Department of Pediatrics, St. Marianna University School of Medicine Hospital, Kawasaki
  • 14 Department of Hematology and Oncology, Miyagi Children's Hospital, Sendai
  • 15 Department of Pediatrics, Nippon Medical School, Tokyo
  • 16 Department of Pediatrics, Sapporo Medical University School of Medicine, Sapporo
  • 17 Department of Hematology/Oncology, Chiba Children's Hospital, Chiba
  • 18 Department of Pediatrics, Chiba University Graduate School of Medicine, Chiba
  • 19 Department of Pediatrics, Tokyo Medical and Dental University, Tokyo
  • 20 Department of Pediatrics, Toho University School of Medicine, Tokyo
  • 21 Department of Pediatrics, Mie University, Tsu, Mie
  • 22 Department of Pediatrics, Hokkaido University Graduate School of Medicine, Sapporo
  • 23 Department of Transplantation and Cell Therapy, Children's Cancer Center, National Center for Child Health and Development, Tokyo, Japan; Department of Pediatric Hematology and Oncology Research, National Center for Child Health and Development, Tokyo, Japan; Department of Pediatrics, the University of Tokyo, Tokyo. katom-tky@umin.ac.jp
Haematologica, 2021 07 01;106(7):2026-2029.
PMID: 33504140 DOI: 10.3324/haematol.2020.266320

* Title and MeSH Headings from MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.

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