Customised weight-based volume contrast media protocol in CT of chest, abdomen and pelvis examination

Yap LPP 1 , Wong JHD 2 , Muhammad Gowdh NF 3 , Ng WL 3 , Chung E 3 , Eturajulu RC 1 Show all authors , Foo SAMK 4 , Vijayananthan A 3 , Sani FM 3

Affiliations 

  • 1 Department of Biomedical Imaging, Faculty of Medicine, University of Malaya, 50603 Kuala Lumpur, Malaysia; Department of Biomedical Imaging, University of Malaya Medical Centre, Lembah Pantai, 59100 Kuala Lumpur, Malaysia; Research Unit of Biomedical Imaging, University of Malaya Medical Centre, Lembah Pantai, 59100 Kuala Lumpur, Malaysia
  • 2 Department of Biomedical Imaging, Faculty of Medicine, University of Malaya, 50603 Kuala Lumpur, Malaysia. Electronic address: jeannie_wong80@um.edu.my
  • 3 Department of Biomedical Imaging, Faculty of Medicine, University of Malaya, 50603 Kuala Lumpur, Malaysia; Department of Biomedical Imaging, University of Malaya Medical Centre, Lembah Pantai, 59100 Kuala Lumpur, Malaysia
  • 4 Department of Biomedical Imaging, University of Malaya Medical Centre, Lembah Pantai, 59100 Kuala Lumpur, Malaysia; Research Unit of Biomedical Imaging, University of Malaya Medical Centre, Lembah Pantai, 59100 Kuala Lumpur, Malaysia
J Med Imaging Radiat Sci, 2021 06;52(2):257-264.
PMID: 33531272 DOI: 10.1016/j.jmir.2021.01.003

Abstract

INTRODUCTION: Fixed volume (FV) contrast media administration during CT examination is the standard practice in most healthcare institutions. We aim to validate a customised weight-based volume (WBV) method and compare it to the conventional FV methods, introduced in a regional setting.

METHODS: 220 patients underwent CT of the chest, abdomen and pelvis (CAP) using a standard FV protocol, and subsequently, a customised 1.0 mL/kg WBV protocol within one year. Both image sets were assessed for contrast enhancement using CT attenuation at selected regions-of-interest (ROIs). The visual image quality was evaluated by three radiologists using a 4-point Likert scale. Quantitative CT attenuation was correlated with the visual quality assessment to determine the HU's enhancement indicative of the image quality grades. Contrast media usage was calculated to estimate cost-savings from both protocols.

RESULTS: Mean patient age was 61 ± 14 years, and weight was 56.1 ± 8.7 kg. FV protocol produced higher contrast enhancement than WBV, p 

* Title and MeSH Headings from MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.

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