Estimation of patient effective doses in PET/CT- 18F-Sodium Fluoride examinations

Alnaaimi M 1 , Sulieman A 2 , Tamam N 3 , Alkhorayef M 4 , Alduaij M 5 , Mohammedzein T 5 Show all authors , Alomair OI 6 , Alashban Y 6 , Salah H 7 , Abd-Elghany AA 8 , Omer H 9 , Bradley DA 10

Affiliations 

  • 1 Radiation Physics Department, Kuwait Cancer Control Center, Shwiekh, Kuwait. Electronic address: m.alnaaimi@gmail.com
  • 2 Radiology and Medical Imaging Department, College of Applied Medical Sciences, Prince Sattam Bin Abdulaziz University, P.O.Box 422, Alkharj, 11942, Saudi Arabia; College of Medical Radiologic Science, Sudan University of Science and Technology, P.O.Box 1908, Khartoum, 11111, Sudan
  • 3 Physics Department, College of Sciences, Princess Nourah Bint Abdulrahman University, P.O Box 84428, Riyadh, 11671, Saudi Arabia
  • 4 Department of Radiological Sciences, College of Applied Medical Sciences, King Saud University, PO Box 10219, Riyadh, 11433, Saudi Arabia; Centre for Nuclear and Radiation Physics, Department of Physics, University of Surrey, Guildford, Surrey, GU2 7XH, UK
  • 5 Radiation Physics Department, Kuwait Cancer Control Center, Shwiekh, Kuwait
  • 6 Department of Radiological Sciences, College of Applied Medical Sciences, King Saud University, PO Box 10219, Riyadh, 11433, Saudi Arabia
  • 7 INAYA Medical Collage, Nuclear Medicine Department, Riyadh, Saudi Arabia
  • 8 Radiology and Medical Imaging Department, College of Applied Medical Sciences, Prince Sattam Bin Abdulaziz University, P.O.Box 422, Alkharj, 11942, Saudi Arabia; Biophysics Department, Faculty of Science, Cairo University, Egypt
  • 9 Department of Basic Sciences, Deanship of Preparatory Year and Supporting Studies, Imam Abdulrahman Bin Faisal University P.O.Box 1982, Dammam, 34212, Saudi Arabia
  • 10 Centre for Nuclear and Radiation Physics, Department of Physics, University of Surrey, Guildford, Surrey, GU2 7XH, UK; Centre for Applied Physics and Radiation Technologies, School of Engineering and Technology, Sunway University, 47500, Bandar Sunway, Selangor, Malaysia
Appl Radiat Isot, 2021 Dec;178:109965.
PMID: 34688024 DOI: 10.1016/j.apradiso.2021.109965

Abstract

The positron emitters (18F-Sodium Fluoride (NaF)) and X-rays used in Positron emission tomography (PET) combined with computed tomography (PET/CT) imaging have a high radiation dose, which results in a high patient dose. The present research intends to determine the radiation dose and risks associated with PET/CT- 18F-Sodium fluoride examinations in patients. The 18F-NaF PET/CT was used to investigate the doses of 86 patients. Patient exposure parameters and ImPACT software were used to calculate mean effective doses. The administered activity of 185 MBq (5.0 mCi) per procedure has a mean and range based on the patient's BMI (BMI). The range of patient effective doses per procedure was found to be 4-10 mSv, with a radiation risk of 1 × 10-5 per procedure. Patient doses are determined by the patient's size, scanner type, imaging protocol, and reconstruction method. For further dose reduction, proper justification and radiation dose optimization is required.

* Title and MeSH Headings from MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.

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