MyMedR

Fulltext Congenital diaphragmatic hernia in a post-partum woman

Abdullah M

Med J Malaysia, 2003 Mar;58(1):99-101.

Congenital diaphragmatic hernia (CDH) is rare in adults. We report a 24 year old woman presenting with shortness of breath, chest pain and nausea after the birth of her first baby. Clinical examination, plain radiography and a CT scan revealed herniation of abdominal contents into her left chest. Via a midline laparotomy, the contents were reduced and the defect repaired, using a mesh. She remains symptom-free three years since her surgery and even after a second childbirth. A brief review of the literature reporting adult diaphragmatic hernia of congenital origin accompanies this case report. We conclude that symptomatic CDH in adults usually presents as an emergency with gastrointestinal and occasionally respiratory complications. Early diagnosis and repair is essential to avoid subsequent morbidity and mortality.

Matched MeSH terms: Hernia, Diaphragmatic/diagnosis*; Hernia, Diaphragmatic/surgery

The Utility of Diagnostic Laparoscopy in Post-Bariatric Surgery Patients with Chronic Abdominal Pain of Unknown Etiology

Alsulaimy M, Punchai S, Ali FA, Kroh M, Schauer PR, Brethauer SA, et al.

Obes Surg, 2017 Aug;27(8):1924-1928.

PMID: 28229315 DOI: 10.1007/s11695-017-2590-0

PURPOSE: Chronic abdominal pain after bariatric surgery is associated with diagnostic and therapeutic challenges. The aim of this study was to evaluate the yield of laparoscopy as a diagnostic and therapeutic tool in post-bariatric surgery patients with chronic abdominal pain who had negative imaging and endoscopic studies.

METHODS: A retrospective analysis was performed on post-bariatric surgery patients who underwent laparoscopy for diagnosis and treatment of chronic abdominal pain at a single academic center. Only patients with both negative preoperative CT scan and upper endoscopy were included.

RESULTS: Total of 35 post-bariatric surgery patients met the inclusion criteria, and all had history of Roux-en-Y gastric bypass. Twenty out of 35 patients (57%) had positive findings on diagnostic laparoscopy including presence of adhesions (n = 12), chronic cholecystitis (n = 4), mesenteric defect (n = 2), internal hernia (n = 1), and necrotic omentum (n = 1). Two patients developed post-operative complications including a pelvic abscess and an abdominal wall abscess. Overall, 15 patients (43%) had symptomatic improvement after laparoscopy; 14 of these patients had positive laparoscopic findings requiring intervention (70% of the patients with positive laparoscopy). Conversely, 20 (57%) patients required long-term medical treatment for management of chronic abdominal pain.

CONCLUSION: Diagnostic laparoscopy, which is a safe procedure, can detect pathological findings in more than half of post-bariatric surgery patients with chronic abdominal pain of unknown etiology. About 40% of patients who undergo diagnostic laparoscopy and 70% of patients with positive findings on laparoscopy experience significant symptom improvement. Patients should be informed that diagnostic laparoscopy is associated with no symptom improvement in about half of cases.

Matched MeSH terms: Hernia, Abdominal/diagnosis; Hernia, Abdominal/etiology; Hernia, Abdominal/surgery

Fulltext Factors affecting decision for hysterectomy: experience in a tertiary teaching hospital in Malaysia: a cross-sectional study

Alzergany, Maha Makluf, Noor Azmi Mat Adenan, Aizura Syafinaz Ahmad Adlan

Malaysian Journal of Public Health Medicine, 2014;14(3):0-0.

MyJurnal

Hysterectomy is one of the most common non-obstetric surgical procedures performed on women. Little is known about the factors affecting decision making process regarding hysterectomy in Malaysia. The study aimed to explore factors affecting women decision regarding hysterectomy among Malaysian women. This study has enrolled 100 women eligible for hysterectomy in the department of general gynecology ward in the university of Malaya hospital, Malaysia. A structured questionnaire was administered by interview. Descriptive analysis was used to obtain the frequencies. Chi square test and simple logistic regression test were performed to assess the association between variables. The majority of participants aged 41-50 years (52%) and married (74%). Twenty seven out of 100 participants made their decision on the operation within one month while 73 women decided after one month. Some complications were only known by the minority of patients such as injury to ureter (47%), injury to nerve (8%), incision hernia (18%), vault prolapse (21 %), and deep vein thrombosis (43%). Most of women delay their decision on the surgery (73%). Factors associated significantly with decision were ethnicity, religion, knowledge on complication, discussion with spouse and doctor.. Cultural factors, opinion of husband and doctors and knowledge of the complication play an important role in the decision of women. It is important to provide suitable information and social support for patients to help them in their decision-making. Participation and support from spouses and doctors should also be encouraged.

Matched MeSH terms: Hernia

Reply to comment to Meta-analysis and systematic review of laparoscopic versus open mesh repair for elective incisional hernia. Jensen K, Jorgensen LN

Awaiz A, Rahman F, Hossain MB, Yunus RM, Khan S, Memon B, et al.

Hernia, 2015 Dec;19(6):1027-9.

PMID: 26496998 DOI: 10.1007/s10029-015-1432-z

Matched MeSH terms: Hernia, Ventral/surgery*

Case of spontaneous hernia through the transverse mesocolon

BALASEGARAM M

Med J Malaya, 1963 Mar;17:187-90.

PMID: 13969251

Matched MeSH terms: Hernia*

Fabrication of green composite hand knitted silk mesh reinforced with silk hydrogel

Bokhari N, Ali A, Yasmeen A, Khalid H, Safi SZ, Sharif F

Int J Biol Macromol, 2023 Dec 31;253(Pt 6):127284.

PMID: 37806415 DOI: 10.1016/j.ijbiomac.2023.127284

Soft tissue defects like hernia and post-surgical fistula formation can be resolved with modern biomaterials in the form of meshes without post-operative complications. In the present study hand knitted silk meshes were surface coated with regenerated silk fibroin hydrogel and pure natural extracts. Two phytochemicals (Licorice extract (LE) and Bearberry extract (BE)) and the two honeybee products (royal jelly (RJ) and honey (HE)) were incorporated separately to induce antibacterial, anti-inflammatory, and wound healing ability to the silk hydrogel coated knitted silk meshes. Meshes were dip coated with a blend of 4 % silk hydrogel (w/v) and 5 % extracts. Dried modified meshes were characterized using SEM, DMA, GC-MS and FTIR. Antimicrobial testing, in-vitro cytotoxicity, in-vitro wound healing and Q-RT-PCR were also performed. SEM analysis concluded that presence of coating reduced the pore size up to 47.7 % whereas, fiber diameter was increased up to 17.9 % as compared to the control. The presence of coating on the mesh improved the mechanical strength/Young's modulus by 1602.8 %, UTS by 451.7 % and reduced the % strain by 51.12 %. Sustained release of extracts from MHRJ (62.9 % up to 72 h) confirmed that it can induce antibacterial activity against surgical infections. Cytocompatibility testing and gene expression results suggest that out of four variables MHRJ presented best cell viability, % wound closure and expression of wound healing marker genes. In-vivo analyses in rat hernia model were carried out using only MHRJ variant, which also confirmed the non- toxic nature and wound healing characteristics of the modified mesh. The improved cell proliferation and activated wound healing in vitro and in vivo suggested that MHRJ could be a valuable candidate to promote cell infiltration and activate soft tissue and hernia repair as a biomedical implant.

Matched MeSH terms: Hernia

Clinical course of gastroesophageal reflux disease and impact of treatment in symptomatic young patients

Bonavina L, Fisichella PM, Gavini S, Lee YY, Tatum RP

Ann N Y Acad Sci, 2020 12;1481(1):117-126.

PMID: 32266986 DOI: 10.1111/nyas.14350

In symptomatic young patients with gastroesophageal reflux symptoms, early identification of progressive gastroesophageal reflux disease (GERD) is critical to prevent long-term complications associated with hiatal hernia, increased esophageal acid and nonacid exposure, release of proinflammatory cytokines, and development of intestinal metaplasia, endoscopically visible Barrett's esophagus, and dysplasia leading to esophageal adenocarcinoma. Progression of GERD may occur in asymptomatic patients and in those under continuous acid-suppressive medication. The long-term side effects of proton-pump inhibitors, chemopreventive agents, and radiofrequency ablation are contentious. In patients with early-stage disease, when the lower esophageal sphincter function is still preserved and before endoscopically visible Barrett's esophagus develops, novel laparoscopic procedures, such as magnetic and electric sphincter augmentation, may have a greater role than conventional surgical therapy. A multidisciplinary approach to GERD by a dedicated team of gastroenterologists and surgeons might impact the patients' lifestyle, the therapeutic choices, and the course of the disease. Biological markers are needed to precisely assess the risk of disease progression and to tailor surveillance, ablation, and management.

Matched MeSH terms: Hernia, Hiatal

Fulltext Mutations in KEOPS-complex genes cause nephrotic syndrome with primary microcephaly

Braun DA, Rao J, Mollet G, Schapiro D, Daugeron MC, Tan W, et al.

Nat Genet, 2017 Oct;49(10):1529-1538.

PMID: 28805828 DOI: 10.1038/ng.3933

Galloway-Mowat syndrome (GAMOS) is an autosomal-recessive disease characterized by the combination of early-onset nephrotic syndrome (SRNS) and microcephaly with brain anomalies. Here we identified recessive mutations in OSGEP, TP53RK, TPRKB, and LAGE3, genes encoding the four subunits of the KEOPS complex, in 37 individuals from 32 families with GAMOS. CRISPR-Cas9 knockout in zebrafish and mice recapitulated the human phenotype of primary microcephaly and resulted in early lethality. Knockdown of OSGEP, TP53RK, or TPRKB inhibited cell proliferation, which human mutations did not rescue. Furthermore, knockdown of these genes impaired protein translation, caused endoplasmic reticulum stress, activated DNA-damage-response signaling, and ultimately induced apoptosis. Knockdown of OSGEP or TP53RK induced defects in the actin cytoskeleton and decreased the migration rate of human podocytes, an established intermediate phenotype of SRNS. We thus identified four new monogenic causes of GAMOS, describe a link between KEOPS function and human disease, and delineate potential pathogenic mechanisms.

Matched MeSH terms: Hernia, Hiatal/genetics*

The "Best" Inguinal Hernia Repair Technique

Chai FY

World J Surg, 2020 10;44(10):3322-3323.

PMID: 32524160 DOI: 10.1007/s00268-020-05636-6

Matched MeSH terms: Hernia, Inguinal/surgery*

Fulltext Inguinal hernia repair by surgical trainees at a Malaysian teaching hospital

Chan KY, Rohaizak M, Sukumar N, Shaharuddin S, Jasmi AY

Asian J Surg, 2004 Oct;27(4):306-12.

PMID: 15564185

To assess the outcome of inguinal hernia repaired by surgical trainees at Universiti Kebangsaan Malaysia Hospital.

Matched MeSH terms: Hernia, Inguinal/surgery*

Fulltext Handlebar herniation: a case of near missed abdominal injury

Chew KS, Amin NM

Med J Malaysia, 2009 Jun;64(2):170-1.

PMID: 20058582 MyJurnal

Timely identification of specific injuries in a polytrauma case is of paramount importance in order to reduce morbidity and mortality. Unfortunately, some of these injuries are subtle and can be missed on initial primary and secondary assessments. In this paper, we report one such injury in a case of a 16-year old motorcyclist who complained of abdominal pain over the right lumbar region after the motorcycle handlebar hit his abdomen. Although initial assessment was uneventful, he was subsequently diagnosed to have a traumatic abdominal wall herniation on abdominal computed tomography after more than 24 hours of observation in the ward.

Matched MeSH terms: Hernia, Abdominal/etiology*; Hernia, Abdominal/radiography

Vaginal inguinal hernia with loose bodies

Chong ATS

Journal of the Malaya Branch of the British Medical Association, 1939;3:104-6.

Matched MeSH terms: Hernia, Inguinal

An unusual type of inguinal hernia

Chong TS

Journal of the Malaya Branch of the British Medical Association, 1937;1:76-7.

Matched MeSH terms: Hernia, Inguinal

Fulltext Does mesh augmentation of the hiatal repair with gore bio-A® improve symptomatic outcomes in laparoscopic fundoplication?

Christodoulidou, M., Kosai, N.R., Rajan, R., Hassan, S., Dac, S., Sutton, P.A., et al.

International Medical Journal Malaysia, 2015;14(1):43-48.

MyJurnal

Introduction: Laparoscopic fundoplication is performed for the management of symptomatic hiatus hernias and gastro-oesophageal reflux disease (GORD) refractory to medical therapy. We adopted the use of Gore Bio-A® for selected laparoscopic hiatus hernia repairs in 2011 and with this case series aimed to establish whether mesh augmentation affects symptomatic outcomes. Methods: A retrospective review of prospectively collected data from all laparoscopic fundoplications performed by a single surgeon between October 2011 and January 2013 was performed. Patient specific data were entered into a proforma and analysed using Microsoft ExcelTM. Patient reported outcomes were assessed with a system specific quality of life questionnaire (GORD-HRQL) both pre and post-operatively. Results: Twenty-three patients underwent laparoscopic fundoplication during the study period. Gore Bio-A® re-enforcement of the hiatal repair was used in 14 patients and was the preferred option for those with pre-operative evidence of a large hiatus hernia. Whilst overall there was a statistically significant difference between pre and post-operative scores (21 vs 0, p=

Matched MeSH terms: Hernia, Hiatal

Fulltext Imaging modalities for an uncommon inguinal scrotal pathology: A case report and literature review

Chun KH, Inn FX, Hing EY, Hong GE

Urol Ann, 2017 11 10;9(4):387-389.

PMID: 29118545 DOI: 10.4103/UA.UA_69_17

Inguinal scrotal swelling is a common presentation to surgical clinic with various differential diagnoses. In most circumstances, a good clinical assessment is sufficient to identify the diagnosis. Imaging is necessary when diagnostic difficulty was encountered. The choice of imaging study could affect the management and outcome. A 60-year-old male presented with an enlarging right inguinal scrotal swelling for 5 years. Clinical examination showed a swelling extended from the right inguinal region down to the right scrotum, firm, not reducible, and not separable from the right testis. Differential diagnoses range from the malignant testicular tumor, irreducible inguinal hernia to the soft-tissue tumor. Ultrasonography and computed tomography scan were unable to conclude the origin of the tumor and involvement of the right testis. Inguinal exploration with potential radical orchiectomy was planned and caused much distress to the patient, resulted in delay in surgery. Intraoperatively, the mass was separated from the testis and spermatic cord, and thus, excision biopsy was performed sparing the testis and spermatic cord. Histopathological examination showed cellular angiofibroma. The right choice of imaging modality is important to provide a precise diagnosis and better treatment plan. This could avoid the unnecessary distress to the patient for potential organ lost. A review through the literature showed the ability of magnetic resonance imaging to better delineate the anatomy of inguinal scrotal soft-tissue mass and thus should have been the imaging modality of choice.

Matched MeSH terms: Hernia, Inguinal

Congenital diaphragmatic hernia: a case report

Damodaran A, Nair S, Somasundram R

Med J Malaysia, 1973 Dec;28(2):99-102.

PMID: 4276265

Matched MeSH terms: Hernia, Diaphragmatic/radiography; Hernia, Diaphragmatic/surgery

Notes on the radical cure of hernia

Dick W

Journal of the Malaya Branch of the British Medical Association, 1903.

Matched MeSH terms: Hernia

Fulltext Adult Bochadalek hernia complicated with perforated gastric ulcer: preoperative diagnosis with multiplanar CT

Faizah MZ, Sharifah MI, Johoruddin K, Juliana AL

Med J Malaysia, 2011 Oct;66(4):367-8.

PMID: 22299562 MyJurnal

Matched MeSH terms: Hernia, Diaphragmatic/complications*; Hernia, Diaphragmatic/radiography

Fulltext Obturator hernia: a rare condition with common surgical symptoms

Fitreena A.A., Shahidah C.A., Mohd. Nizam M.H., Wan Zainira W.Z., Wong, M.P.K.

Journal of Biomedical and Clinical Sciences, 2018;3(1):35-38.

MyJurnal

Hernia is a common surgical problem. However, worldwide
incidence of obturator hernia is

Matched MeSH terms: Hernia, Obturator

Fulltext [Intractable intraoperative brain herniation secondary to tension pneumocephalus: a rare life-threatening complication during drainage of subdural empyema]

Foo LL, Chaw SH, Chan L, Ganesan D, Karuppiah R

Rev Bras Anestesiol, 2016 09 28;67(6):655-658.

PMID: 27692367 DOI: 10.1016/j.bjan.2015.09.006

Tension pneumocephalus is rare but has been well documented following trauma and neurosurgical procedures. It is a surgical emergency as it can lead to neurological deterioration, brainstem herniation and death. Unlike previous cases where tension pneumocephalus developed postoperatively, we describe a case of intraoperative tension pneumocephalus leading to sudden, massive open brain herniation out of the craniotomy site. The possible causative factors are outlined. It is imperative to rapidly identify possible causes of acute intraoperative brain herniation, including tension pneumocephalus, and institute appropriate measures to minimize neurological damage.

Matched MeSH terms: Hernia/etiology*

Displaying publications 1 - 20 of 98 in total