MyMedR

Fulltext Ambulatory carbon dioxide laser haemorrhoidectomy without disability

Yap CM

Med J Malaysia, 1997 Mar;52(1):97-8.

PMID: 10968064

Matched MeSH terms: Laser Therapy*

980-nm laser therapy versus varicose vein surgery in racially diverse Penang, Malaysia

Lakhwani MN, Dadlani NI, Wong YC

ANZ J Surg, 2009 May;79(5):352-7.

PMID: 19566516 DOI: 10.1111/j.1445-2197.2009.04888.x

Chronic venous disorders are conditions of increasing prevalence in the developing world, and venous ulceration is the terminal sequel. Currently there are only limited data on all aspects of this from Southeast Asia. The aim of the present study was to assess differences in the demography and outcome between varicose vein surgery (VVS) and the relatively new endovenous laser therapy (EVT) in patients from Penang, Malaysia.

Matched MeSH terms: Laser Therapy/methods*

Fulltext Outpatient procedures for cervical dysplasia: a 3 year review of laser vaporisation and LEEP

Lee KE, Koh CF, Watt WF

Med J Malaysia, 1999 Mar;54(1):47-51.

PMID: 10972004

A 3 year retrospective review (1995 to 1997) of 127 patients with cervical dysplasia who underwent Laser Vaporisation of the cervix and LEEP at the Gynaecological Cancer Centre, KK Women's & Children's Hospital, Singapore, was undertaken. Amongst the patients in the Laser Vaporisation group, the mean age was 37.7 years (SD 8.8), the mean operating time was 14.8 minutes (SD 8.5), 63.6% were given prophylactic antibiotics and the mean follow up period was 15.3 months (SD 12.0), whilst in the LEEP group, mean age was 40.3 years (SD 8.4), mean operating time, 11.8 minutes (SD 4.9), prophylactic antibiotic rate, 53.8% and mean follow up period was 19.1 months (SD 9.3). Mild and moderate haemorrhage post procedure were the only complications encountered, 10.2% (5/49) in the Laser group and 3.8% (3/78) in the LEEP group. 98% (48/49) and 97.4% (76/78) of the Laser and LEEP groups, respectively, were free of disease on follow up. None of the 3 patients with persistent or recurrent disease were diagnosed as having invasive cancer. Overall, there were no significant differences in the patient characteristics, histopathology, operating times, follow up period, the use of prophylactic antibiotics, and complications in the 2 groups. The low complication rate, high disease-free rate and the relatively short operating time of Laser Vaporisation and LEEP in our study suggests that, indeed, both the procedures can be done safely and efficiently in the outpatient setting. However the discrepancy between the histology of colposcopically directed biopsy and that of LEEP specimens suggests that colposcopically directed biopsy may not be as accurate as one might believe, and further studies analysing the concordance between colposcopically directed biopsy and LEEP biopsy histologies are needed.

Matched MeSH terms: Laser Therapy*

Retinopathy of prematurity in extremely low birth weight infants in Malaysia

Choo MM, Martin FJ, Theam LC, U-Teng C

J AAPOS, 2009 Oct;13(5):446-9.

PMID: 19840721 DOI: 10.1016/j.jaapos.2009.06.008

To identify differences in incidence, risk factors, and outcomes of retinopathy of prematurity (ROP) between 2 birth weight categories within a cohort of extremely low birth weight (ELBW) infants in Malaysia.

Matched MeSH terms: Laser Therapy

Interventional laser surgery for oral potentially malignant disorders: a longitudinal patient cohort study

Thomson PJ, Goodson ML, Cocks K, Turner JE

Int J Oral Maxillofac Surg, 2017 Mar;46(3):337-342.

PMID: 27866683 DOI: 10.1016/j.ijom.2016.11.001

Oral squamous cell carcinoma (OSCC) is a lethal disease, with rising incidence. There were 6767 new OSCC cases and 2056 deaths in the UK in 2011. Cancers are preceded by oral potentially malignant disorders (PMDs), recognizable mucosal diseases harbouring increased SCC risk, offering clinicians a 'therapeutic window' to intervene. Contemporary practice remains unable to predict lesion behaviour or quantify malignant transformation risk. No clear management guidelines exist and it is unclear from the literature whether early diagnosis and intervention prevents cancer. Between 1996 and 2014, 773 laser treatments were performed on 590 PMD patients in Newcastle maxillofacial surgery departments. The efficacy of the intervention was examined by review of the clinicopathological details and clinical outcomes of the patients (mean follow-up 7.3 years). Histopathology required up-grading in 36.1% on examining excision specimens. Seventy-five percent of patients were disease-free, mostly younger patients with low-grade dysplasia; 9% exhibited persistent disease and were generally older with proliferative verrucous leukoplakia. Disease-free status was less likely for erythroleukoplakia (P=0.022), 'high-grade' dysplasia (P<0.0001), and with lichenoid inflammation (P=0.028). Unexpected OSCC was identified in 12.0%, whilst 4.8% transformed to malignancy. Interventional laser surgery facilitates definitive diagnosis and treatment, allows early diagnosis of OSCC, identifies progressive disease, and defines outcome categories. Evidence is lacking that intervention halts carcinogenesis. Multicentre, prospective, randomized controlled trials are needed to confirm the efficacy of surgery.

Matched MeSH terms: Laser Therapy

Letter to Editor re: 'Mechanochemical endovenous ablation of saphenous veins using the ClariVein: A systematic review' - MOCA data reporting needs to be tighter and standardized!

Saravana K, Tang TY

Phlebology, 2017 12;32(10):679-681.

PMID: 28764596 DOI: 10.1177/0268355517724618

Matched MeSH terms: Laser Therapy

Valsalva haemorrhagic retinopathy after push-ups

Hassan M, Tajunisah I

Lancet, 2011 Feb 5;377(9764):504.

PMID: 21255827 DOI: 10.1016/S0140-6736(10)60677-0

Matched MeSH terms: Laser Therapy

Fulltext Laser versus dissection technique of tonsillectomy

Wan Ishlah L, Fahmi AM, Srinovianti N

Med J Malaysia, 2005 Mar;60(1):76-80.

PMID: 16250284

Tonsillectomy is the single most common operation performed in Ear Nose and Throat Department. Various methods of tonsillectomy have been practiced over the century aimed at reducing or eliminating intraoperative and postoperative morbidity. Due to various blood supplies received, intraoperative bleeding is the most difficult problem and securing it is time-consuming. The time taken to control the bleeding would invariably determine the length of operation. Common postoperative complications are bleeding and pain. This study evaluated the operative time, intraoperative blood loss, postoperative pain and other postoperative complications of tonsillectomy performed by laser as compared to conventional dissection technique. This is a prospective randomized study whereby sixty patients were divided into two groups of equal number. In one group, the tonsillectomy performed by laser and in the other group the tonsillectomy performed by conventional dissection technique. Operative time and amount of blood loss is significantly reduced in the laser group. Total postoperative pain and post operative complications were not significantly different between the two groups. Tonsillectomy by using laser have shown less intraoperative bleeding and shortened the operative time. In the hospital where laser machine and expertise are available, it is justifiable to use this technique as effective method of performing tonsillectomy.

Matched MeSH terms: Laser Therapy*

Potentially malignant disorders revisited-The lichenoid lesion/proliferative verrucous leukoplakia conundrum

Thomson PJ, Goodson ML, Smith DR

J Oral Pathol Med, 2018 Jul;47(6):557-565.

PMID: 29663518 DOI: 10.1111/jop.12716

BACKGROUND: Clinically identifiable potentially malignant disorders (PMD) precede oral squamous cell carcinoma development. Oral lichenoid lesions (OLL) and proliferative verrucous leukoplakia (PVL) are specific precursor lesions believed to exhibit both treatment resistance and a high risk of malignant transformation (MT).

METHODS: A retrospective review of 590 PMD patients treated in Northern England by CO2 laser surgery between 1996 and 2014 was carried out. Lesions exhibiting lichenoid or proliferative verrucous features were identified from the patient database and their clinicopathological features and outcome post-treatment determined at the study census date of 31 December 2014.

RESULTS: One hundred and 98 patients were identified as follows: 118 OLL and 80 PVL, most frequently leukoplakia at ventrolateral tongue and floor of mouth sites, equally distributed between males and females. Most exhibited dysplasia on incision biopsy (72% OLL; 85% PVL) and were treated by laser excision rather than ablation (88.1% OLL; 86.25% PVL). OLL were more common in younger patients (OLL 57.1 year; PVL 62.25 years; P = .008) and more likely than PVL to present as erythroleukoplakia (OLL 15.3%; PVL 2.5%; P = .003). Whilst no significant difference was seen between OLL and PVL achieving disease-free status (69.5% and 65%, respectively; P = .55), this was less than the overall PMD cohort (74.2%). MT was identified in 2 OLL (1.7%) and 2 PVL (2.5%) during follow-up.

CONCLUSION: One-third of PMD cases showed features of OLL or PVL, probably representing a disease presentation continuum. Post-treatment disease-free status was less common in OLL and PVL, although MT was infrequent.

Matched MeSH terms: Laser Therapy

Fulltext Haemangioma of the uvula causing loud habitual snoring--a rare entity

Thong JF, Pang KP, Siow JK

Med J Malaysia, 2008 Dec;63(5):408-9.

PMID: 19803302

Mucosal haemangiomas are unusual and typically involve frequently traumatised areas such as the lip, buccal mucosa and lateral borders of the tongue. Uvular haemangioma is rare and to our knowledge, has never been reported to cause obstructive sleep apnoea (OSA). We report an unusual case of uvular haemangioma causing loud habitual snoring and symptoms suggestive of OSA. This case report illustrates a rare cause of OSA and demonstrates the efficacy of surgery for obvious obstructive lesions of the pharynx.

Matched MeSH terms: Laser Therapy/methods

Recurrent respiratory papillomatosis

Long YT, Sani A

Asian J Surg, 2003 Apr;26(2):112-6.

PMID: 12732496

A 6-year-review of patients who presented with recurrent respiratory papillomatosis (RRP) to our hospital from January 1996 to December 2001 was carried out. Ten cases were identified, of which six were juvenile-onset RRP. Hoarseness was the most common symptom, noted in nine (90%) patients. Other clinical presentations included cough, stridor and aphonia. All patients had glottic papillomas; two had multiple sites of involvement. One patient underwent a tracheostomy that revealed papillomas over the trachea, bronchus and lung parenchyma. Half of the patients were Chinese. Of the six cases of juvenile-onset RRP, three patients were Malay, two Chinese and one Indian. Three Chinese and one German patient had adult-onset RRP. Among the juvenile-onset RRP cases, the mean age at presentation was 2 years, while for adult-onset RRP, it was 42 years. Juvenile-onset RRP was more common in females. There were more papillomas over more sites in patients with juvenile-onset RRP than with adult-onset disease. Subglottic involvement was noted in the juvenile-onset RRP cases. All patients were treated with CO2 laser therapy, but there was complete remission of the papillomas in only two cases.

Matched MeSH terms: Laser Therapy

Carbon dioxide laser stomaplasty for tracheostomal stenosis

Sani A

J Laryngol Otol, 1998 May;112(5):467-8.

PMID: 9747477

A method of treating tracheostomal stenosis post-laryngectomy is described. The carbon dioxide (CO2) laser is used to fashion and ablate two triangular areas lateral to the stenosed stoma to provide an immediate enlarged stoma for comfortable breathing. This simple procedure is done under local anaesthesia, is almost bloodless, safe and takes just 10 minutes. Over the last five years eight patients underwent this procedure and seven had a satisfactory stoma without the need to use a tracheostomy tube.

Matched MeSH terms: Laser Therapy*

Lip adhesion: unusual complication of Stevens-Johnson syndrome

Royan SJ

J Oral Maxillofac Surg, 2010 Apr;68(4):901-3.

PMID: 19926381 DOI: 10.1016/j.joms.2009.02.011

Matched MeSH terms: Laser Therapy

Late closure of argon laser iridotomies following regrowth of iris pigment epithelium

Teoh LO, Ishikawa H, Liebmann JM, Ritch R

Arch. Ophthalmol., 2000 Jul;118(7):989-90.

PMID: 10900117

Matched MeSH terms: Laser Therapy*

Fulltext Laser tonsillotomy in children with tonsillar hyperplasia

Baharudin A, Shahid H, Rhendra MZ

Med J Malaysia, 2006 Aug;61(3):377-9.

PMID: 17240597 MyJurnal

Tonsillectomy in children is performed on a regular basis in ENT. The indications are chronic tonsillitis, sleep apnea to deeper structures. The natural history of tonsillar hyperplasia is regression when a child is six years beyond. In children with bilateral tonsillar hyperplasia we studied the use of laser as an alternative procedure to reduce the bulk of the tonsillar mass. Children with symptoms of bilateral tonsillar hyperplasia underwent laser tonsillotomy. The tonsils were dissected using carbon dioxide (CO2) laser. The tonsillar bed was left untouched. Intraoperative and postoperative conditions were noted.

Matched MeSH terms: Laser Therapy/methods*

Fulltext Swiftlase assisted CO2 laser ablation in the treatment of nasal obstruction due to hypertrophy of the inferior turbinates

Sani A, Primuharsa P

Med J Malaysia, 2001 Jun;56(2):174-9.

PMID: 11771077

Hypertrophy of the inferior turbinates are the major cause of nasal obstruction. CO2 lasers have been used to reduce the size of the inferior turbinates over the last 20 years. However, the many techniques of delivery of the laser show that there is no one standard method reducing the size of the turbinates. We now describe how the laser can be applied directly to the turbinates using a handpiece with a special nasal tip, thus overcoming the disadvantages delivery via arthroscopic devices, microscopes and fibers. This technique is further enhanced by coupling it with Swiftlase which swirls the focused beam in a 3 mm spot thus ablating tissue more quickly. This procedure is done under local anaesthesia. The ablation of the anterior third of the inferior turbinates effectively overcomes nasal obstruction. This new method was compared to the more traditional submucus diathermy. 22 patients were subjected to laser treatment whilst 20 patients were subjected to diathermy. The outcome was evaluated subjectively by the patients themselves at 2 weeks, 3 months and 6 months. At the end of the study, the laser group reported a more significantly improved nasal airway (91% against 75%) and decreased rhinorrhea (72.7% against 35%) when compared to the diathermy group.

Matched MeSH terms: Laser Therapy/instrumentation; Laser Therapy/methods*

Chemoreduction for intraocular retinoblastoma in Malaysia

Menon BS, Juraida E, Alagaratnam J, Mohammad M, Ibrahim H, George TM, et al.

J Pediatr Hematol Oncol, 2007 Jan;29(1):2-4.

PMID: 17230058

In the last decade, chemotherapy in combination with focal therapy (chemoreduction) has been increasingly used in intraocular retinoblastoma to avoid enucleation and radiotherapy. The aim of this study was to assess the feasibility and outcome of chemoreduction in Malaysian children with retinoblastoma. This was a prospective study from August 2001 to January 2006. Twenty children (25 eyes) were given 4 cycles of chemoreduction, after which the response was assessed. Fourteen eyes showed a complete response, 10 eyes showed a partial response, and 1 eye had progressive disease. Twelve eyes developed progressive disease later, 9 after an initial complete response and 3 after a partial response. Overall, progressive disease occurred in 52%. There were 2 treatment failures, in Reese-Elsworth groups 3 and 4. Both eyes required enucleation. One eye in group 5 required second line chemotherapy to achieve a complete response. No eyes were irradiated. Five children (25%) defaulted follow-up, one of whom returned with disseminated disease. In conclusion, 4 cycles of chemoreduction achieved a durable complete response in only 12% of eyes. Chemoreduction is feasible in Malaysia but requires good patient compliance and close follow-up.

Matched MeSH terms: Laser Therapy

Fulltext The Effects Of CO2 Laser On Oral Lichen Planus And Lichenoid Lesions

Kok, T.C., Ong, S.T.

Ann Dent, 2001;8(1):-.

MyJurnal

The purpose of this study is to assess the effectiveness of C02 laser in relieving symptoms associated with Oral lichen planus (aLP) and lichenoid lesions (aLL) and the event of healing. Six patients were selected for this study with 13 sites treated. Each lesion was ablated with C02 laser and the wound allowed to heal undisturbed. Prior to treatment, 4 patients had both unprovoked and provoked pain and 2 patients rated for provoked pain only. After laser ablation, five out of six patients treated recorded no pain / 0 pain score. One month post-laser, the treated area was almost the same colour as the surrounding normal mucosa and soft in texture in all but one patient in which there was some fibrosis and residual plaque-like patch. Weconclude that the use of C02 laser in the treatment of aLP and aLL shows positive results in relieving symptoms associated with these lesions.

Matched MeSH terms: Laser Therapy

Fulltext Hydrocarbon sources for the carbon nanotubes production by chemical vapour deposition: A review

Hayder Baqer Abdullah, Irmawati Ramli, Ismayadi Ismail, Nor Azah Yusof

Pertanika Journal of Science & Technology, 2017;25(2):379-396.

MyJurnal

The synthesis of carbon nanotubes (CNTs) using a chemical vapour deposition (CVD) method requires the use of hydrocarbon as the carbon precursor. Among the commonly used hydrocarbons are methane and acetylene, which are both light gas-phase substances. Besides that, other carbon-rich sources, such as carbon monoxide and coal, have also been reportedly used. Nowadays, researches have also been conducted into utilising heavier hydrocarbons and petrochemical products for the production of CNTs, such as kerosene and diesel oil. Therefore, this article reviews the different kind of hydrocarbon sources for CNTs production using a CVD method. The method is used for it allows the decomposition of the carbon-rich source with the aid of a catalyst at a temperature in the range 600-1200°C. This synthesis technique gives an advantage as a high yield and high-quality CNTs can be produced at a relatively low cost process. As compared to other processes for CNTs production such as arc discharge and laser ablation, they may produce high quality CNTs but has a disadvantage for use as large scale synthesis routes.

Matched MeSH terms: Laser Therapy

Recurrent gigantic pyogenic granuloma disturbing speech and mastication: a case report and literature review

Ong MA, Chai WL, Ngeow WC

Ann Acad Med Singap, 1998 Mar;27(2):258-61.

PMID: 9663321

A case of gigantic pyogenic granuloma with three recurrences in the lower anterior gingiva is presented. Surgical wide excision of the lesion is the treatment of choice. The tumour must be excised down to the periosteum and the irritants around it removed to avoid recurrence. A contributing factor to the gigantic lesion is hormonal changes during pregnancy. Long-term review for 18 months after the third surgery showed no evidence of recurrence at the surgical site.

Matched MeSH terms: Laser Therapy

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