MyMedR

Huge uterine fibroid in a postmenopausal woman associated with polycythaemia: a case report

Abdul Ghaffar NA, Ismail MP, Nik Mahmood NM, Daud K, Abu Dzarr GA

Maturitas, 2008 Jun 20;60(2):177-9.

PMID: 18482807 DOI: 10.1016/j.maturitas.2008.03.013

Uterine fibroid or leiomyoma is the commonest benign uterine tumour. Its occurrence in the postmenopausal age group is rare and if enlargement of the fibroid noted during this time, the diagnosis of leiomyosarcoma is provisional until proven otherwise. A case of a postmenopausal woman with a huge uterine fibroid associated with polycythaemia is presented whereby the mass was noted to increase in size within 2 years. The patient was otherwise well except for the growing uterine mass. She had venesection done to treat her polycythaemia and later underwent surgery for total abdominal hysterectomy and bilateral salpingoophoorectomy. The histopathology report confirmed leiomyoma of uterus with no evidence of sarcomatous changes. It was suggested that large uterine myoma may cause secondary polycythaemia by three postulated mechanisms, i.e. presence of hypoxia suggesting shunting within the tumour, second, the uterine fibroid was compressing the ureters resulting in inappropriate excessive production of erythropoietin by the kidneys, and third, the tumour itself may have been producing the erythropoietin.

Matched MeSH terms: Leiomyoma/complications*

Fulltext Magnetic resonance-guided focused ultrasound surgery (MRgFUS) treatment for uterine fibroids

Abdullah B, Subramaniam R, Omar S, Wragg P, Ramli N, Wui A, et al.

Biomed Imaging Interv J, 2010 Apr-Jun;6(2):e15.

PMID: 21611036 MyJurnal DOI: 10.2349/biij.6.2.e15

Magnetic Resonance-guided focused Ultrasound Surgery (MRgFUS) is gaining popularity as an alternative to medical and surgical interventions in the management of symptomatic uterine fibroids. Studies have shown that it is an effective non-invasive treatment with minimal associated risks as compared to myomectomy and hysterectomy. MRgFUS can be offered to a majority of patients suffering from symptomatic uterine fibroids. It has been suggested that the use of broader inclusion criteria as well as the mitigation techniques makes it possible to offer MRgFUS to a much larger subset of patients than previously believed. This paper will describe how MRgFUS treatment for uterine fibroids is performed at the University of Malaya Medical Centre, Kuala Lumpur, Malaysia.

Matched MeSH terms: Leiomyoma

Laparoscopic versus abdominal myomectomy: trend and pattern of practice among reproductive age population in Kedah, Malaysia

Ahmad MF, Sheng KL, Kathirgamanathan S, Kannaiah K

Minerva Ginecol, 2018 10;70(5):644-645.

PMID: 29464941 DOI: 10.23736/S0026-4784.18.04183-7

Matched MeSH terms: Leiomyoma/pathology; Leiomyoma/surgery*

Fulltext Inadvertent posterior lower segment caesarean section in a sacculated uterus

Choong KH, Sivanesaratnam V, Sinnathuray TA

Med J Malaysia, 1981 Dec;36(4):250-3.

PMID: 7334964

Matched MeSH terms: Leiomyoma/diagnosis*; Leiomyoma/surgery

Fulltext The role of abdominal angiography in difficult gastrointestinal bleeding

Ding PH, Wong TJ

Med J Malaysia, 1994 Sep;49(3):306-9.

PMID: 7845288

Two cases of leiomyomas of the jejunum presenting with gastrointestinal bleeding of uncertain origin are described. Diagnosis was finally established by selective angiography. Laparotomy and resection of the tumour were successfully performed. The approach and management of this rare tumour are outlined.

Matched MeSH terms: Leiomyoma/complications; Leiomyoma/radiography*; Leiomyoma/surgery

Fulltext Improvement in Quality of Life after Myomectomy

Ehab Helmy Abdel Malek Fahmy, Constance Liew Sat Lin, Alvin Oliver Payus, Rhanye Mac Guad, May Zaw Soe, Satishratnam Nagaratnam, et al.

Borneo Journal of Medical Sciences, 2020;14(1):55-59.

MyJurnal

Dysmenorrhea is one of the leading causes of pelvic pain and menstrual disorder among women during childbearing age. The burden of dysmenorrhea is greater than any other gynaecological complaint. Some women have severe dysmenorrhea which renders them incapacitated for days each menstrual cycle requiring absence from study or duty, frequently requiring pain killer, restriction of daily performance, poor sleep, negative moods such as anxiety and depression. A 31-year-old female presented with severe dysmenorrhea and heavy menstrual bleeding (HMB) as a cause of multiple uterine fibroids, underwent surgeries to remove 100 fibroids from her uterus which has improved her quality of life, eliminating her dysmenorrhea and menstrual abnormalities

Matched MeSH terms: Leiomyoma

Fulltext Case report: Leiomyoma of the anterior abdominal wall

Ernest Ong CW, Siow SL

Med J Malaysia, 2016 04;71(2):81-2.

PMID: 27326950 MyJurnal

Leiomyomas are benign soft tissue swellings of smooth muscle origin, most commonly found in the uterus. Extra uterine leiomyomas presenting as an abdominal mass is often a diagnostic challenge as such occurrence is rare. We present a rare case of primary abdominal wall leiomyoma, and highlight the importance of laparoscopic approach in the diagnosis and treatment of such tumour.

Matched MeSH terms: Leiomyoma/diagnosis*

Congenital Midline Tongue Base Mass in An Infant: Lingual Hamartoma

Fadzilah N, Azman M, See GB

J Clin Diagn Res, 2016 Sep;10(9):MD01-MD03.

PMID: 27790477

Lingual hamartoma is a rare finding of congenital midline posterior tongue mass. The lesion may be seen as a single anomaly or maybe associated with syndrome especially the Oral Facial Digital Syndrome (OFDS). Here, we report an otherwise normal and healthy two-month-old boy with a congenital midline base of tongue mass presented with snoring and episodic vomiting since the age of 1 month. Tumour excision from the area of foramen of caecum recovered a pinkish pedunculated tumour. Histopathology examination confirmed the diagnosis of leiomyomatous lingual hamartoma. Differential diagnosis, especially for midline tongue mass and other paediatric tongue lesions are discussed. We also discuss the epidemiology, histopathologic features, treatment and prognosis of lingual hamartoma based on the literature review.

Matched MeSH terms: Leiomyoma

A case of Stein-Leventhal syndrome complicated by large multiple fibromyomas

Fook CW

Med J Malaya, 1970 Jun;24(4):314-6.

PMID: 4248357

Matched MeSH terms: Leiomyoma/complications*

Concordance between hysteroscopic impression and endometrial histopathological diagnosis

Gan DE, Jawan RA, Moy FM

Prev Med, 2013;57 Suppl:S21-3.

PMID: 23313791 DOI: 10.1016/j.ypmed.2012.12.026

The aim of this study was to evaluate the accuracy of hysteroscopic impression for diagnosing benign and malignant endometrial pathology.

Matched MeSH terms: Leiomyoma/diagnosis; Leiomyoma/pathology

Uterine arteriovenous malformation - Possible association to uterine fibroids?

Gan F, Vikneswaran V, Yu KK

Med J Malaysia, 2021 03;76(2):273-274.

PMID: 33742646

A 32-year-old, gravida 2 para 0+1, was managed in Selayang Hospital, Selangor for uterine fibroids in pregnancy and placenta previa major. The lady went into preterm labour at 33 weeks, requiring emergency Caesarean section. Intraoperatively, we found a thinned-out bulge between the intramural uterine fibroids at the posterior uterine wall, which then perforated and was repaired. Persistent bleeding post operatively led to relaparotomy and hysterectomy. Histology of the uterus reported arteriovenous malformation (AVM). We postulate the possibility of these lesions coexisting with uterine fibroids. Screening for uterine AVMs in patients with fibroids may lead to early detection with option of embolization; deferring the need for hysterectomy.

Matched MeSH terms: Leiomyoma

Uterine leiomyomata in pregnancy

Hasan F, Arumugam K, Sivanesaratnam V

Int J Gynaecol Obstet, 1991 Jan;34(1):45-8.

PMID: 1671020

Sixty cases with uterine leiomyomata in pregnancy are presented. The incidence was 1 in 1033 deliveries. The median age of the patients was 33.4 years. The majority were primigravidae (60%). A significant number of patients gave a history of infertility (43%) and spontaneous abortions (25%). The commonest antenatal complication was malpresentation and in all these patients the myomata were larger than 6 cm. Typical features of red degeneration occurred in 10% of cases. The cesarean section rate was 73%, the commonest indication being obstructed labor. Severe hemorrhage was encountered at cesarean section in 10 patients, 3 of whom needed hysterectomy. There were no perinatal deaths.

Matched MeSH terms: Leiomyoma/complications; Leiomyoma/epidemiology*; Leiomyoma/surgery

Fulltext Recurrent glossal leiomyoma

Idayu MY, Irfan M, Othman NH

Med J Malaysia, 2012 Jun;67(3):329-30.

PMID: 23082428 MyJurnal

Oral leiomyomas are rare benign tumour of smooth muscle. The first case of oral leiomyoma was reported by Blanc in 1884 and since then more cases has been published following advancement in immunohistochemical study. This tumour has an excellent prognosis and recurrences are extremely rare. We report a case of a recurrent glossal leiomyoma in a patient with HIV infection and the lesion recurred one year after the first excision.

Matched MeSH terms: Leiomyoma/pathology; Leiomyoma/surgery*

Fulltext Lipoleiomyoma: a rare benign tumour of the uterus

Johari B, Koshy M, Sidek S, Hanafiah M

BMJ Case Rep, 2014 Oct 19;2014.

PMID: 25331147 DOI: 10.1136/bcr-2014-205814

Matched MeSH terms: Leiomyoma/diagnosis*

Fulltext Lipoleiomyoma of the uterus

Karikalan B, Pasupathi T

Indian J Pathol Microbiol, 2017 Jan-Mar;60(1):128-129.

PMID: 28195112 DOI: 10.4103/0377-4929.200052

Matched MeSH terms: Leiomyoma/complications*; Leiomyoma/diagnosis*; Leiomyoma/pathology

Fulltext Volumetric MRI-guided, high-intensity focused ultrasound ablation of uterine leiomyomas: ASEAN preliminary experience

Keserci B, Duc NM, Nadarajan C, Huy HQ, Saizan A, Wan Ahmed WA, et al.

Diagn Interv Radiol, 2020 May;26(3):207-215.

PMID: 32209511 DOI: 10.5152/dir.2019.19157

PURPOSE: We sought to present our preliminary experience on the effectiveness and safety of magnetic resonance imaging (MRI)-guided, high-intensity focused ultrasound (HIFU) therapy using a volumetric ablation technique in the treatment of Association of Asian Nations (ASEAN) patients with symptomatic uterine leiomyomas.

METHODS: This study included 33 women who underwent HIFU treatment. Tissue characteristics of leiomyomas were assessed based on T2- and T1-weighted MRI. The immediate nonperfused volume (NPV) ratio and the treatment effectiveness of MRI-guided HIFU on the basis of the degrees of volume reduction and improvement in transformed symptom severity score (SSS) were assessed.

RESULTS: The median immediate NPV ratio was 89.8%. Additionally, the median acoustic sonication power and HIFU treatment durations were 150 W and 125 min, respectively. At six-month follow-up, the median leiomyoma volume had decreased from 139 mL at baseline to 84 mL and the median transformed SSS had decreased from 56.2 at baseline to 18.8. No major adverse events were observed.

CONCLUSION: The preliminary results demonstrated that volumetric MRI-guided HIFU therapy for the treatment of symptomatic leiomyomas in ASEAN patients appears to be clinically acceptable with regard to treatment effectiveness and safety.

Matched MeSH terms: Leiomyoma/therapy*

Pharmacists' viewpoint on the care for patients with uterine fibroids during the COVID-19 pandemic

Kow CS, Ramachandram DS, Hasan SS

BJOG, 2024 Jun;131(7):1018.

PMID: 37016474 DOI: 10.1111/1471-0528.17477

Matched MeSH terms: Leiomyoma*

Recurrent uterine myomata in three sisters--an uncommon occurrence

Kulenthran A, Sivanesaratnam V

Int J Gynaecol Obstet, 1988 Oct;27(2):289-91.

PMID: 2903099

Three sisters who developed recurrent uterine myomata from a very young age are presented. Despite repeated attempts at myomectomy, all three cases had hysterectomies ultimately. Complications encountered during surgery were severe hemorrhage, inadvertent injury to bladder and bowel in two patients and a rare complication of colonic-uteric-cutaneous fistula occurring post-operatively in one patient. Histology of the final hysterectomy specimens in two cases showed low grade leiomyosarcoma and cellular myoma, respectively.

Matched MeSH terms: Leiomyoma/genetics*

Utero-cutaneous fistula after caesarean section secondary to red degeneration of intramural fibroid

Lim PS, Shafiee MN, Ahmad S, Hashim Omar M

Sex Reprod Healthc, 2012 Jun;3(2):95-6.

PMID: 22578758 DOI: 10.1016/j.srhc.2012.03.002

A 33 year-old woman had an emergency caesarean section for retained second twin which was complicated by utero-cutaneous fistula due to red degeneration of intramural fibroid. The utero-cutaneous communication was demonstrated by an examination under anaesthesia using dye test. She then underwent excision of the fistula tract and myomectomy. She recovered well following the surgery. This is the first case of utero-cutaneous fistula where the communication is between the endometrial cavity and skin lesion via a necrotic intramural fibroid following caesarean section. Fistulogram might fail to demonstrate the communication. In highly suspected case, other modalities of investigations could be utilised.

Matched MeSH terms: Leiomyoma/pathology*

Goserelin versus leuprolide before hysterectomy for uterine fibroids

Lim SS, Sockalingam JK, Tan PC

Int J Gynaecol Obstet, 2008 May;101(2):178-83.

PMID: 18164303 DOI: 10.1016/j.ijgo.2007.10.020

To compare goserelin and leuprolide given before hysterectomy for symptomatic large fibroid uteri.

Matched MeSH terms: Leiomyoma/pathology; Leiomyoma/therapy*

Displaying publications 1 - 20 of 39 in total