MyMedR

Fulltext Retinoblastoma in an older child: a case report

Ong, Wu Zhuan, Jamalia Rahmat, Ramasamy, Sunder, Amir Samsudin

Malaysian Journal of Medicine and Health Sciences, 2018;14(2):93-96.

MyJurnal

Retinoblastoma is a rare intraocular malignant tumour more commonly seen in children below five years of age. We presented a rare case of retinoblastoma in an older child. A nine-year-old girl noticed that she had loss of vision OS following a fall at home. Her vision was 6/6 OD and only light perception OS. Examination of the left eye revealed an extensive exudative retinal detachment. Her right eye examination was unremarkable. CT scan showed a left eye intraocular mass with calcification. EUA revealed a mixed endophytic and exophytic mass with extensive exudative retinal detachment. Family members consented to left eye enucleation and histopathological report confirmed the diagnosis of retinoblastoma. Post enucleation, patient is doing well with a prosthetic eye. In conclusion, any unexplained visual loss in children regardless of age warrants a full ophthalmological examination as the possibility of retinoblastoma cannot be ruled out.

Matched MeSH terms: Retinal Detachment

Fulltext Bilateral Giant Retinal Tear and Sequential Vitrectomy

Mustapha M, Roufail Franzco E

Case Rep Ophthalmol, 2017 08 17;8(2):436-439.

PMID: 28924443 DOI: 10.1159/000479728

PURPOSE: To describe the excellent outcome of surgery for bilateral giant retinal tears (GRTs) with better options of endotamponade.

METHODS: This is a case report of a 62-year-old man who presented with bilateral GRTs and associated retinal detachment. The tear in the right eye was supero-temporal and silicone oil was used as an endotamponade. The tear in the left eye was infero-temporal and perfluorocarbon liquid was used as an endotamponade.

RESULTS: The outcome at 6 months after surgery was excellent with visual acuities of 6/6 in both eyes.

CONCLUSION: Improved availability of endotamponade agents allows repair of bilateral GRTs to be done at the same time, with good surgical outcomes.

Matched MeSH terms: Retinal Detachment

Fulltext Familial exudative vitreoretinopathy presenting with unilateral rhegmatogenous retinal detachment in a Malay teenager

Leow SN, Bastion ML

BMJ Case Rep, 2013;2013.

PMID: 23645703 DOI: 10.1136/bcr-2013-009664

To describe a case of familial exudative vitreoretinopathy presenting with unilateral rhegmatogenous retinal detachment in a Malay teenager.

Matched MeSH terms: Retinal Detachment/diagnosis*; Retinal Detachment/surgery

Fulltext Surgical management of unilateral rhegmatogenous retinal detachment associated with ocular coloboma in a 7-year-old child with Noonan syndrome

Bastion ML, Qader AM

BMJ Case Rep, 2011;2011.

PMID: 22696753 DOI: 10.1136/bcr.02.2011.3889

The authors would like to present an unusual case of unilateral retinal detachment, phacodonesis, dense cataract and ocular coloboma in a 7-year-old Indian Muslim boy with Noonan syndrome. He underwent lensectomy, 23G pars planar vitrectomy, air fluid exchange, endolaser and silicone oil injection which successfully reattached the retina. His best corrected visual acuity was 6/24 6 months after the surgery and oil removal.

Matched MeSH terms: Retinal Detachment/etiology; Retinal Detachment/surgery*

Fulltext Saved by the buckle: primary buckle vitrectomy for macular hole detachment due to rapid progression of premacular fibrosis in acute retinal necrosis

Bastion ML

BMJ Case Rep, 2010;2010.

PMID: 22736756 DOI: 10.1136/bcr.11.2009.2488

This report describes the rapid progress of a case of unilateral acute retinal necrosis (ARN) that led to formation of a macular hole rhegmatogenous retinal detachment with advanced proliferative vitreo-retinopathy (PVR) changes over the space of 2 weeks. This necessitated primary vitrectomy with circumferential scleral buckle placement, which facilitated reattachment of the retina.

Matched MeSH terms: Retinal Detachment/etiology*; Retinal Detachment/surgery*

Fulltext Central serous choroidopathy in pregnancy

Normalina M, Zainal M, Alias D

Med J Malaysia, 1998 Dec;53(4):439-41.

PMID: 10971992

Central serous choroidopathy is a spontaneous serous detachment of the sensory retina, usually affecting adults between 20 to 50 years of age but is also found in patients older than 60 years of age. This disease usually affects males with a male to female ratio of 8-10 to 1. Many aetiological or associated factors have been described. Here we report a 39-year-old pregnant lady presented with left central serous chorioretinopathy preceded by an unusual emotional disturbance. She was not given any photocoagulative treatment to avoid possible photocoagulative complications. Post delivery, she presented with resolution of the CSC.

Matched MeSH terms: Retinal Detachment/pathology; Retinal Detachment/psychology*

Bilateral Norrie's disease in identical twins

Sukumaran K

Br J Ophthalmol, 1991 Mar;75(3):179-80.

PMID: 2012789

A case of Norrie's disease in an identical twins is reported. No positive family history was obtained. The couple had no other children. The older of the twins died at the age of 9 months of uncertain cause. To the best of my knowledge this is the first case of Norrie's disease reported in Malaysia. And its occurrence in an identical twins is very rare.

Matched MeSH terms: Retinal Detachment/congenital; Retinal Detachment/pathology

Surgery of aphakic retinal detachment

Singh M

Br J Ophthalmol, 1988 Nov;72(11):820-2.

PMID: 3207656

In a prospective study 84 patients with aphakic retinal detachment were treated either by local scleral buckling alone or combined with an encirclement. The rate of surgical reattachment of the retina was found to be similar with either technique over a minimum follow-up period of one year. Simplicity and a low incidence of serious complications of the local procedure merit its application as the initial method of repairing aphakic detachments.

Matched MeSH terms: Retinal Detachment/etiology; Retinal Detachment/surgery*

Fulltext Pneumatic retinopexy for treatment of posterior pole detachment following vitreoretinal surgery for diabetic tractional retinal detachment threatening the fovea

Bastion ML

BMJ Case Rep, 2012;2012.

PMID: 22878988 DOI: 10.1136/bcr-2012-006303

To describe the usage of 100% perfluoropropane and subsequent laser retinopexy for the repair of posterior pole retinal detachment in a previously vitrectomised patient with diabetic tractional detachment.

Matched MeSH terms: Retinal Detachment/etiology; Retinal Detachment/physiopathology; Retinal Detachment/surgery*

Fulltext A novel de novo mutation in COL2A1 gene associated with fetal skeletal dysplasia

Chu FC, Hii LY, Hung TH, Lo LM, Hsieh TT, Shaw SW

Taiwan J Obstet Gynecol, 2021 Mar;60(2):359-362.

PMID: 33678343 DOI: 10.1016/j.tjog.2021.01.017

OBJECTIVE: Skeletal dysplasias, caused by genetic mutations, are a heterogenous group of heritable disorders affecting bone development during fetal life. Stickler syndrome, one of the skeletal dysplasias, is an autosomal dominant connective tissue disorder caused by abnormal collagen synthesis owing to a genetic mutation in COL2A1.

CASE REPORT: We present the case of a 38-year-old multipara woman whose first trimester screening showed a normal karyotype. However, the bilateral femur and humerus length symmetrically shortened after 20 weeks. Next-generation sequencing for mutations in potential genes leading to skeletal dysplasia detected a novel de novo mutation (c.1438G > A, p.Gly480Arg) in COL2A1, causing Stickler syndrome type 1. This pathogenic mutation might impair or destabilize the collagen structure, leading to collagen type II, IX, and XI dysfunction.

CONCLUSION: We identified a novel de novo mutation in COL2A1 related to the STL1 syndrome and delineated the extent of the skeletal dysplasia disease spectrum.

Matched MeSH terms: Retinal Detachment/diagnosis*; Retinal Detachment/embryology; Retinal Detachment/genetics*

Fulltext Retinal redetachment after pneumatic retinopexy – the importance of case selection

Muhammad Najmi, K., Aida Zairani, M.Z., Mushawiahti, M., Bastion, M.L.C., Amin, A.

Journal of Surgical Academia, 2017;7(2):18-20.

MyJurnal

Pneumatic retinopexy is known as one of the treatment options for a specific type of retinal detachment. It is done in
an office setting and may be the most cost-effective means of retinal reattachment surgery. Location and size of the
retinal break remain as the major criteria for a successful outcome. We describe a case that fulfilled all except one
major criteria for pneumatic retinopexy and underwent multiple procedures but failed. Fluctuation in the resolution
of the retinal detachment such as in this particular case suggested possibility of early treatment failure.

Matched MeSH terms: Retinal Detachment

Ocular presentations and toxoplasma serology

Zurainee MN, Khairul Anuar A, Fong MY, Hoh HB, Choon J, Rahmah N

JUMMEC, 2000;5:98-102.

During the period 1996-1998, 134 patients suspected of having ocular toxoplasmosis were seen in the Ophthalmology Clinic of the University Hospital, Kuala Lumpur. Clinical presentations in these patients ranged from poor vision to severe retinal detachment. Of these patients, 72% were confirmed positive for Toxoplasma gondii infection by serological methods. Chorioretinjtis and vitritis were found to be the most apparent symptoms, both having 100%correlation with serological positivity, This was followed by uveitis, floaters, and retinal detachment with correlation at 78%, 75%and 75%, respectively. However, there was no correlation between level of serotitre and ocular presentations. KEYWORDS: Toxoplasmosis, serology, chorioretinitis, uveitis

Matched MeSH terms: Retinal Detachment

Fulltext Retinal break adjacent to the optic disc causing retinal detachment in a pathological myopia

Noor Aniah, A., Bastion, M.L.C., Mushawiahti, M.

Journal of Surgical Academia, 2017;7(2):21-23.

MyJurnal

Retinal detachment is one of the common complications of pathological myopia due to presence of retinal break.
However, retinal break commonly occurs in the peripheral retina. This case report illustrates the rare incidence of
retinal break adjacent to the optic disc, highlights the possible causes of poor visual outcome following surgical
repair as well as the possible measures to treat the complications.

Matched MeSH terms: Retinal Detachment

Fulltext Hidden Choroidal Melanoma Presented with Bullous Non-rhegmatogenous Retinal Detachment in a Myopic Asian Lady: A Rare Manifestation

Ibrahim N, Sakinah Z, Abdul Ghani Z, Ibrahim M

Cureus, 2019 Mar 27;11(3):e4335.

PMID: 31187000 DOI: 10.7759/cureus.4335

Choroidal melanoma is an uncommon malignant melanoma among non-Caucasians. We report here a case of a high myope patient who presented with symptoms of acute retinal detachment, which had been diagnosed as possible rhegmatogenous retinal detachment from the initial assessment. A detailed vitreoretinal evaluation revealed a glimpse of an obscured intraocular mass underneath the detached retina, which later proved to be a choroidal melanoma. This is an unexpected cause of retinal detachment in a myopic eye. Furthermore, the rare nature of choroidal melanoma in this particular region of the world makes this an ignored diagnosis at presentation.

Matched MeSH terms: Retinal Detachment

Treatment of macular hole retinal detachment

Lai YK

Br J Ophthalmol, 1990 Apr;74(4):201-2.

PMID: 2337542

Seven patients with macular hole retinal detachment were treated by intravitreal gas injection with or without release of subretinal fluid. Macular buckling, diathermy, cryopexy, or vitrectomy were not used. The patients were placed prone for eight hours a day until the gas had absorbed. In five of the seven patients the retina became reattached within three days and remained reattached with follow-up periods of three to 22 months (average nine months). It is believed that such detachments are due to vitreoretinal traction and the intravitreal gas bubble relieves this traction. This technique is simple, safe, and does not require costly or sophisticated instruments. It has an added advantage in preserving macular function.

Matched MeSH terms: Retinal Detachment/etiology; Retinal Detachment/pathology; Retinal Detachment/therapy*

Fulltext "Miotic-induced retinal detachment": a case report

Singh M

Med J Malaysia, 1985 Jun;40(2):136-8.

PMID: 3834285

A rare case of pilocarpine-induced retinal detachment occurring in the only useful myopic eye of a young Chinese woman is described. Problems of treating raised intraocular pressure in high-risk cases of retinal detachment are discussed.

Matched MeSH terms: Retinal Detachment/chemically induced*

Fulltext Images in clinical medicine. Retinal detachment in malignant hypertension

Tajunisah I, Patel DK

N Engl J Med, 2009 Aug 27;361(9):899.

PMID: 19710488 DOI: 10.1056/NEJMicm0802683

Matched MeSH terms: Retinal Detachment/etiology*; Retinal Detachment/pathology

Bilateral Exudative Retinal Detachment in Septo-Optic Dysplasia

Addenan M, May CM

Indian Pediatr, 2017 12 15;54(12):1058-1059.

PMID: 29317570

Matched MeSH terms: Retinal Detachment*